Best TWAS P=1.72e-99 · Best GWAS P=9.71e-98 conditioned to 0.19
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | LPL | 0.09 | 0.00 | bslmm | 668 | 0.02 | 1.0e-03 | 19.95 | -14.8 | 1.7e-49 | -0.62 | 0.04 | 0.86 | TRUE |
| 2 | NTR | Blood | LPL | 0.08 | 0.05 | bslmm | 667 | 0.06 | 5.5e-20 | 17.17 | 16.9 | 8.1e-64 | 0.91 | 0.02 | 0.98 | FALSE |
| 3 | YFS | Blood | LPL | 0.06 | 0.07 | lasso | 2 | 0.06 | 6.5e-20 | 18.80 | 18.8 | 1.1e-78 | 0.89 | 1.00 | 0.00 | TRUE |
| 4 | YFS | Blood | LZTS1 | 0.06 | 0.03 | enet | 21 | 0.03 | 1.2e-10 | -0.86 | -6.1 | 1.1e-09 | -0.21 | 1.00 | 0.00 | TRUE |
| 5 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | LPL | 0.03 | 0.00 | blup | 88 | 0.00 | 1.3e-01 | 12.61 | 21.2 | 1.7e-99 | 0.67 | 0.07 | 0.14 | TRUE |
| 6 | The Cancer Genome Atlas | Brain Lower Grade Glioma | LPL | 0.09 | 0.12 | lasso | 4 | 0.11 | 3.5e-12 | 19.90 | -19.6 | 2.3e-85 | -0.59 | 1.00 | 0.00 | FALSE |