Best TWAS P=1.85e-50 · Best GWAS P=2.12e-49 conditioned to 0.00405
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | YFS | Blood | DAB2 | 0.20 | 0.20 | lasso | 14 | 0.21 | 3.0e-67 | 13.31 | -13.9 | 1.0e-43 | 0.90 | 1.00 | 0.00 | TRUE |
| 2 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | DAB2 | 0.04 | 0.01 | enet | 9 | 0.02 | 3.3e-03 | -14.08 | -10.6 | 2.4e-26 | 0.29 | 0.07 | 0.03 | TRUE |
| 3 | The Cancer Genome Atlas | Lung Adenocarcinoma | C9 | 0.04 | 0.00 | blup | 89 | 0.03 | 2.8e-04 | -2.56 | -5.5 | 2.8e-08 | 0.22 | 0.02 | 0.06 | FALSE |
| 4 | The Cancer Genome Atlas | Prostate Adenocarcinoma | DAB2 | 0.07 | 0.00 | enet | 6 | 0.02 | 2.1e-03 | -0.13 | -5.6 | 1.7e-08 | 0.42 | 0.03 | 0.05 | FALSE |
| 5 | The Cancer Genome Atlas | Uterine Corpus Endometrial Carcinoma | DAB2 | 0.18 | -0.01 | blup | 83 | 0.05 | 2.0e-02 | 3.40 | -14.9 | 1.9e-50 | 0.59 | 0.02 | 0.17 | TRUE |