[Hub]/) : Traits : Heel T-Score : ← →

chr5:41,032,998-43,577,190

Best TWAS P=4.41e-25 · Best GWAS P=6.59e-26 conditioned to 0.373

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	SEPP1	0.06	0.00	blup	330	0.04	1.9e-05	-0.59	5.6	1.9e-08	0.53	0.26	0.35	FALSE
2	GTEx	Adipose Subcutaneous	CCDC152	0.09	0.04	lasso	4	0.02	6.4e-03	-5.04	-5.3	1.3e-07	-0.38	0.88	0.00	FALSE
3	GTEx	Artery Aorta	CCDC152	0.31	0.24	lasso	8	0.24	2.5e-13	-5.11	-5.5	3.5e-08	-0.39	1.00	0.00	FALSE
4	GTEx	Artery Coronary	CCDC152	0.20	0.13	lasso	2	0.12	7.7e-05	-5.11	-5.1	2.9e-07	-0.36	0.68	0.04	FALSE
5	GTEx	Artery Tibial	CCDC152	0.22	0.17	enet	35	0.18	1.8e-14	-5.11	-5.5	3.3e-08	-0.40	1.00	0.00	FALSE
6	GTEx	Artery Tibial	OXCT1-AS1	0.07	0.04	lasso	3	0.03	1.6e-03	7.34	7.5	6.2e-14	0.37	0.26	0.04	FALSE
7	GTEx	Brain Frontal Cortex BA9	GHR	0.14	0.02	lasso	9	0.06	9.9e-03	-8.79	9.4	4.5e-21	0.46	0.11	0.20	FALSE
8	GTEx	Breast Mammary Tissue (Female)	SEPP1	0.15	0.00	enet	29	0.02	1.0e-01	0.62	6.3	2.6e-10	0.48	0.06	0.19	FALSE
9	GTEx	Cells EBV-transformed lymphocytes	OXCT1	0.22	0.17	lasso	4	0.13	4.7e-05	6.43	6.6	5.2e-11	0.36	0.29	0.05	FALSE
10	GTEx	Esophagus Muscularis	CCDC152	0.13	0.09	lasso	8	0.10	7.9e-07	-4.49	-5.4	6.7e-08	-0.37	0.96	0.00	FALSE
11	GTEx	Muscle Skeletal	OXCT1-AS1	0.10	0.02	enet	25	0.08	2.9e-08	1.76	5.2	2.3e-07	0.28	0.46	0.46	FALSE
12	GTEx	Stomach	SERBP1P6	0.12	0.03	enet	16	0.01	6.7e-02	1.81	-5.4	8.0e-08	-0.37	0.08	0.18	FALSE
13	GTEx	Thyroid	GHR	0.08	0.04	enet	25	0.04	2.5e-04	-4.49	-6.2	4.8e-10	-0.32	0.13	0.07	FALSE
14	GTEx	Thyroid	CCDC152	0.10	0.07	lasso	4	0.04	4.2e-04	-5.10	-5.1	3.1e-07	-0.36	0.82	0.01	FALSE
15	ROSMAP	Brain Pre-frontal Cortex	GHR	0.04	0.02	blup	374	0.03	5.4e-05	6.32	8.0	1.0e-15	0.45	0.73	0.02	FALSE
16	ROSMAP	Brain Pre-frontal Cortex	C5orf51	0.03	0.01	bslmm	298	0.02	1.9e-03	1.71	-5.7	1.6e-08	-0.40	0.15	0.51	FALSE
17	ROSMAP	Brain Pre-frontal Cortex	SEPP1	0.18	0.19	lasso	11	0.21	1.3e-26	-5.06	5.3	8.6e-08	0.40	1.00	0.00	FALSE
18	The Cancer Genome Atlas	Breast Invasive Carcinoma	OXCT1	0.03	0.03	enet	8	0.03	1.4e-06	7.84	8.3	9.2e-17	0.39	0.01	0.99	FALSE
19	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	OXCT1	0.04	0.05	blup	58	0.05	9.4e-07	7.92	7.5	7.3e-14	0.40	0.01	0.99	FALSE
20	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	CCDC152	0.11	0.02	enet	7	0.05	1.3e-03	-5.04	5.2	2.4e-07	0.31	0.06	0.31	FALSE
21	The Cancer Genome Atlas	Prostate Adenocarcinoma	GHR	0.12	0.11	enet	6	0.13	2.5e-13	9.23	10.3	4.4e-25	0.85	0.20	0.80	TRUE
22	The Cancer Genome Atlas	Testicular Germ Cell Tumors	OXCT1	0.12	0.02	blup	58	0.06	4.0e-03	7.92	8.0	9.3e-16	0.42	0.01	0.83	FALSE
23	The Cancer Genome Atlas	Thyroid Carcinoma	OXCT1	0.05	0.04	blup	58	0.04	5.3e-05	7.41	5.9	3.4e-09	0.23	0.14	0.74	TRUE