[Hub]/) : Traits : Heel T-Score : ← →

chr5:148,030,064-150,130,084

Best TWAS P=1.38e-10 · Best GWAS P=2.12e-37 conditioned to 3.85e-28

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex PCYOX1L 0.08 0.07 enet 18 0.07 1.7e-08 -4.9 5.6 2.6e-08 0.11 1.00 0.00 FALSE
2 GTEx Brain Cerebellar Hemisphere HMGXB3 0.26 0.17 lasso 3 0.13 2.6e-04 -6.1 -6.0 1.6e-09 -0.04 0.01 0.94 TRUE
3 GTEx Lung HMGXB3 0.11 0.05 enet 13 0.03 1.2e-03 -5.2 -6.0 1.7e-09 -0.06 0.03 0.97 FALSE
4 GTEx Ovary HMGXB3 0.32 0.20 lasso 16 0.30 3.6e-08 -6.1 -5.8 6.7e-09 -0.09 0.02 0.97 FALSE
5 GTEx Pancreas HMGXB3 0.31 0.13 lasso 4 0.10 4.8e-05 -5.5 -5.5 5.1e-08 -0.06 0.06 0.94 FALSE
6 GTEx Spleen HMGXB3 0.33 0.14 lasso 5 0.10 1.4e-03 -5.3 -5.2 2.2e-07 -0.06 0.07 0.63 FALSE
7 GTEx Thyroid HMGXB3 0.15 0.12 lasso 6 0.11 6.4e-09 -5.4 -5.5 3.4e-08 -0.06 0.10 0.90 FALSE
8 ROSMAP Brain Pre-frontal Cortex GRPEL2 0.15 0.10 lasso 4 0.09 1.9e-11 5.2 -5.3 1.1e-07 -0.12 1.00 0.00 FALSE
9 The Cancer Genome Atlas Pancreatic Adenocarcinoma PCYOX1L 0.08 0.06 blup 57 0.06 2.4e-03 -3.1 -6.4 1.4e-10 -0.34 0.03 0.14 TRUE
10 The Cancer Genome Atlas Prostate Adenocarcinoma TIGD6 0.08 0.00 blup 61 0.02 5.8e-03 1.3 5.5 4.5e-08 0.05 0.03 0.74 FALSE