[Hub]/) : Traits : Heel T-Score : ← →

chr1:74,468,533-75,922,251

Best TWAS P=7.65e-10 · Best GWAS P=4.11e-09 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	CRYZ	0.64	0.31	lasso	13	0.47	3.1e-43	5.4	5.5	4.4e-08	-0.77	0.04	0.96	FALSE
2	GTEx	Adipose Visceral Omentum	CRYZ	0.51	0.21	enet	33	0.24	1.6e-12	5.5	5.1	2.7e-07	-0.58	0.04	0.96	FALSE
3	GTEx	Brain Cerebellar Hemisphere	TYW3	0.32	0.20	lasso	13	0.18	2.2e-05	-5.9	6.2	7.7e-10	-0.97	0.01	0.97	TRUE
4	GTEx	Brain Cerebellar Hemisphere	RP11-17E13.2	0.25	0.12	lasso	6	0.04	4.4e-02	-5.9	5.9	3.1e-09	-0.97	0.01	0.95	FALSE
5	GTEx	Brain Cerebellum	CRYZ	0.49	0.17	enet	20	0.17	1.2e-05	5.5	5.4	8.6e-08	-0.52	0.03	0.88	FALSE
6	GTEx	Brain Cerebellum	TYW3	0.34	0.23	enet	18	0.27	1.4e-08	5.5	5.7	1.0e-08	-0.91	0.01	0.99	FALSE
7	GTEx	Brain Cerebellum	RP11-17E13.2	0.28	0.11	enet	24	0.09	1.6e-03	5.5	5.2	2.2e-07	-0.87	0.02	0.97	FALSE
8	GTEx	Brain Cortex	CRYZ	0.46	0.14	lasso	5	0.14	1.4e-04	5.2	6.0	2.7e-09	-0.45	0.04	0.60	FALSE
9	GTEx	Brain Cortex	TYW3	0.34	0.18	lasso	5	0.15	6.4e-05	4.8	5.5	4.7e-08	-0.73	0.05	0.90	FALSE
10	GTEx	Brain Frontal Cortex BA9	TYW3	0.26	0.20	lasso	13	0.18	1.3e-05	5.5	5.5	3.0e-08	-0.66	0.04	0.92	FALSE
11	GTEx	Brain Hypothalamus	RP11-17E13.2	0.29	0.21	enet	15	0.27	4.6e-07	4.8	5.3	1.0e-07	-0.85	0.02	0.96	FALSE
12	GTEx	Brain Nucleus accumbens basal ganglia	RP11-17E13.2	0.40	0.26	lasso	7	0.31	4.6e-09	5.1	5.6	2.1e-08	-0.71	0.05	0.94	FALSE
13	GTEx	Brain Putamen basal ganglia	RP11-17E13.2	0.43	0.10	lasso	8	0.14	3.5e-04	4.8	5.5	3.5e-08	-0.83	0.04	0.89	FALSE
14	GTEx	Breast Mammary Tissue (Female)	CRYZ	0.27	0.12	lasso	7	0.08	1.6e-03	5.2	5.4	5.5e-08	-0.63	0.03	0.79	FALSE
15	GTEx	Heart Left Ventricle	RP11-17E13.2	0.30	0.20	lasso	5	0.23	2.2e-12	5.5	5.2	2.0e-07	-0.88	0.02	0.98	FALSE
16	GTEx	Nerve Tibial	RP11-17E13.2	0.37	0.24	lasso	5	0.31	4.3e-22	4.8	5.2	2.1e-07	-0.89	0.03	0.97	FALSE
17	GTEx	Ovary	RP11-17E13.2	0.34	0.20	lasso	14	0.18	3.0e-05	4.9	5.9	3.5e-09	-0.88	0.02	0.96	FALSE
18	GTEx	Skin Not Sun Exposed Suprapubic	CRYZ	0.61	0.17	lasso	11	0.43	2.4e-25	5.5	5.2	2.5e-07	-0.75	0.03	0.97	FALSE
19	GTEx	Skin Sun Exposed Lower leg	CRYZ	0.54	0.25	enet	20	0.50	2.0e-46	-5.9	5.2	1.5e-07	-0.79	0.00	1.00	FALSE
20	GTEx	Whole Blood	CRYZ	0.19	0.10	lasso	5	0.13	6.4e-12	4.8	5.2	2.4e-07	-0.72	0.07	0.92	FALSE
21	METSIM	Adipose	CRYZ	0.31	0.17	enet	36	0.24	3.9e-35	5.1	5.9	4.3e-09	-0.72	0.04	0.96	FALSE
22	METSIM	Adipose	RP11-17E13.2	0.14	0.10	lasso	15	0.17	2.9e-24	-3.2	5.4	7.9e-08	-0.84	0.01	0.99	FALSE
23	NTR	Blood	CRYZ	0.07	0.01	lasso	4	0.03	3.1e-09	-5.8	5.9	2.9e-09	-0.85	0.01	0.99	FALSE
24	The Cancer Genome Atlas	Glioblastoma Multiforme	CRYZ	0.55	0.33	lasso	6	0.41	1.6e-13	4.9	5.3	1.2e-07	-0.69	0.02	0.98	FALSE
25	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	CRYZ	0.39	0.29	enet	13	0.38	3.5e-45	4.9	5.3	1.1e-07	-0.79	0.02	0.98	FALSE
26	The Cancer Genome Atlas	Rectum Adenocarcinoma	CRYZ	0.21	0.04	blup	54	0.04	4.9e-02	4.9	5.8	6.8e-09	-0.59	0.01	0.67	FALSE