Best TWAS P=3.03e-10 · Best GWAS P=5.11e-07 conditioned to 0.568
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Adipose Visceral Omentum | AC004166.6 | 0.11 | 0.07 | enet | 18 | 0.09 | 2.9e-05 | -5.0 | -5.4 | 6.0e-08 | 0.76 | 0.00 | 0.81 | FALSE |
2 | GTEx | Brain Cerebellum | PMS2P5 | 0.62 | 0.08 | lasso | 6 | 0.22 | 3.3e-07 | -2.6 | 5.4 | 5.2e-08 | -0.74 | 0.01 | 0.84 | FALSE |
3 | GTEx | Cells EBV-transformed lymphocytes | AC004166.6 | 0.20 | 0.02 | lasso | 4 | 0.09 | 6.5e-04 | -5.0 | -6.3 | 3.0e-10 | 0.74 | 0.00 | 0.36 | TRUE |
4 | GTEx | Esophagus Gastroesophageal Junction | PMS2P5 | 0.23 | 0.19 | lasso | 2 | 0.18 | 5.4e-07 | -5.0 | 5.2 | 1.6e-07 | -0.97 | 0.00 | 0.99 | FALSE |