Best TWAS P=1.43e-20 · Best GWAS P=4.96e-21 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Caudate basal ganglia | BICC1 | 0.27 | 0.16 | lasso | 1 | 0.16 | 2.7e-05 | 9.3 | 9.3 | 1.4e-20 | 0.99 | 0.03 | 0.89 | TRUE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | BICC1 | 0.10 | 0.09 | lasso | 10 | 0.10 | 2.1e-13 | -3.5 | 7.2 | 4.5e-13 | 0.61 | 0.92 | 0.08 | FALSE |
| 3 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | BICC1 | 0.07 | 0.00 | blup | 143 | 0.02 | 1.5e-02 | 9.3 | 7.8 | 4.5e-15 | 0.77 | 0.02 | 0.52 | FALSE |