TWAS hub - BICC1

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.119	0.0330	6.2e-07	0.017	0.085	0.092	0.092	0.090	3.2e-03	1.6e-10	2.5e-11	2.6e-11	4.3e-11
2	GTEx	Adipose Subcutaneous	0.093	0.0400	6.0e-03	0.085	NA	0.075	NA	0.076	1.8e-07	NA	1.0e-06	NA	7.9e-07
3	GTEx	Artery Tibial	0.243	0.0554	2.3e-07	0.154	NA	0.100	NA	0.140	4.0e-12	NA	2.9e-08	NA	4.6e-11
4	GTEx	Brain Caudate basal ganglia	0.268	0.0880	1.7e-03	0.156	NA	0.131	NA	0.158	3.1e-05	NA	1.4e-04	NA	2.7e-05
5	GTEx	Esophagus Muscularis	0.104	0.0490	8.9e-03	0.029	NA	0.029	NA	0.042	6.9e-03	NA	6.8e-03	NA	1.4e-03
6	GTEx	Muscle Skeletal	0.340	0.0516	1.7e-11	0.256	NA	0.254	NA	0.259	5.6e-25	NA	9.0e-25	NA	2.8e-25
7	GTEx	Nerve Tibial	0.231	0.0728	3.3e-04	0.182	NA	0.162	NA	0.171	6.7e-13	NA	1.5e-11	NA	3.3e-12
8	GTEx	Skin Sun Exposed Lower leg	0.083	0.0370	6.1e-03	0.111	NA	0.113	NA	0.117	2.0e-09	NA	1.3e-09	NA	6.7e-10
9	ROSMAP	Brain Pre-frontal Cortex	0.104	0.0296	3.2e-07	0.090	0.059	0.095	0.097	0.105	1.2e-11	4.4e-08	3.4e-12	2.0e-12	2.1e-13
10	TCGA	Kidney Renal Papillary Cell Carcinoma	0.070	0.0390	6.7e-03	0.002	0.024	0.006	NA	0.002	2.4e-01	1.5e-02	1.5e-01	NA	2.3e-01
11	TCGA	Testicular Germ Cell Tumors	0.224	0.1120	4.2e-03	-0.005	0.027	0.092	NA	0.029	5.1e-01	3.8e-02	3.8e-04	NA	3.3e-02

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11
Glaucoma (self-reported)	10.9	12.9	23.3	4.8	3.5	3.8	4.2	3.4	3.3	3.5	3.8	4.7	1.4	0.7
Eye problems/disorders: Glaucoma	7.9	9.4	17.3	4.2	2.9	3.2	3.8	3.0	2.7	2.9	3.2	4.0	1.3	1.0
Loneliness, isolation	7.5	10.3	16.0	3.8	3.9	3.9	0.9	3.8	3.5	4.0	3.2	3.7	-0.9	-0.5
Frequency of unenthusiasm / disinterest in last 2 weeks	6.6	8.8	15.5	2.5	3.7	3.7	0.3	3.7	3.6	3.9	3.3	3.2	-0.2	-0.3
Alzheimer’s Disease (including proxy)	5.5	7.9	11.6	3.1	3.1	3.2	2.0	3.2	3.2	3.2	3.2	3.4	0.5	-1.5
Eye problems/disorders: None of the above	5.2	6.0	15.3	-3.9	-1.9	-2.2	-3.4	-1.8	-1.9	-1.8	-2.3	-3.2	-1.5	-1.6
Had major operations	4.8	5.7	16.4	-2.1	-1.4	-1.7	-3.7	-1.2	-1.4	-1.4	-2.0	-2.7	-4.1	-2.5
Wheeze or whistling in the chest in last year	4.5	8.0	12.5	2.2	3.5	3.5	1.5	3.2	3.3	3.4	2.9	3.5	1.9	0.5
Medication: Co-codamol	4.4	5.1	9.3	1.9	2.8	2.7	0.5	3.0	2.6	2.7	2.1	2.5	1.0	1.6
Illnesses of siblings: Diabetes	4.4	5.4	8.8	2.9	2.2	2.4	2.8	2.3	2.1	2.4	2.2	3.0	1.7	1.2
Unable to work because of sickness or disability	4.3	5.6	9.4	1.8	3.0	2.9	-0.3	3.1	3.0	3.0	2.8	2.3	-0.5	-0.2
HDL Cholesterol	4.2	7.1	11.3	-1.9	-2.6	-2.8	-2.8	-2.7	-2.8	-2.7	-3.1	-3.4	-2.7	-0.9
Frequency of depressed mood in last 2 weeks	4.2	5.9	9.0	3.0	2.8	2.9	1.1	2.8	2.9	3.0	2.5	2.8	0.1	-0.1
Financial difficulties in last 2 years	4.1	5.6	8.8	3.0	2.7	2.8	0.9	2.7	3.0	2.7	2.4	2.6	-0.0	-0.7
Illnesses of father: High blood pressure	4.1	5.1	16.7	-1.9	-0.6	-0.9	-3.9	-0.5	-0.8	-0.6	-1.7	-2.2	-4.1	-3.1
Mouth/teeth dental problems: Loose teeth	4.0	4.8	8.1	1.6	2.7	2.6	-0.2	2.8	2.8	2.8	2.5	2.2	-0.7	0.7
Ulcerative Colitis	3.9	5.6	9.0	1.6	2.1	2.3	2.2	1.9	2.3	2.1	2.7	2.7	3.0	2.7
Ever highly irritable/argumentative for 2 days	3.8	4.6	7.5	2.3	2.4	2.4	0.9	2.4	2.5	2.4	2.7	2.3	1.3	0.5
Medication: Amlodipine	3.7	5.2	9.0	-1.8	-2.3	-2.4	-2.5	-2.0	-2.0	-2.2	-1.8	-3.0	-2.8	-2.0
Ulcerative Colitis (UC)	3.6	6.7	9.8	1.5	2.7	2.8	1.6	2.7	3.0	2.9	3.1	2.8	2.1	2.7
Heel T-Score	3.6	28.6	86.5	5.0	3.7	4.4	9.3	3.4	3.4	3.5	3.9	7.2	7.8	2.2
Systolic blood pressure, automated reading	3.6	10.4	24.5	-2.5	-2.5	-3.0	-5.0	-2.4	-2.3	-2.5	-3.0	-4.3	-4.7	-0.9
Hypertension (Self-reported)	3.6	9.9	37.9	-0.9	-1.2	-1.7	-5.8	-1.1	-1.0	-1.0	-1.9	-3.6	-6.2	-3.4
Alzheimer’s Disease (in father)	3.5	3.7	6.3	2.5	1.9	2.0	1.7	2.0	2.2	1.9	2.4	2.3	1.1	0.3
Supplements: Zinc	3.5	3.8	6.2	-1.7	-2.2	-2.3	-0.5	-2.4	-2.5	-2.4	-2.5	-2.0	-0.2	0.7
Medication: Blood pressure	3.5	6.2	28.9	-1.0	-0.8	-1.1	-4.7	-0.7	-0.6	-0.6	-1.3	-2.6	-5.4	-2.3
Average weekly red wine intake	3.5	5.1	9.5	-0.2	-3.0	-3.0	1.1	-3.1	-3.0	-3.0	-2.5	-1.9	-0.1	-0.0
Systolic Blood Pressure	3.3	16.5	45.4	-3.2	-2.7	-3.2	-6.7	-2.7	-2.5	-2.5	-3.4	-5.3	-6.5	-2.5
Current tobacco smoking	3.3	5.3	8.9	1.1	2.5	2.7	2.0	2.3	2.4	2.5	2.4	3.0	2.6	1.2
Medication: Ventolin 100micrograms inhaler	3.3	4.2	7.8	0.8	2.7	2.5	-1.0	2.6	2.5	2.8	2.1	1.8	-0.6	-1.3
Smoking status: Current	3.3	5.2	8.6	1.3	2.5	2.6	2.0	2.2	2.4	2.4	2.4	2.9	2.6	0.8
Medication: Atenolol	3.2	4.0	12.3	-3.5	-1.8	-2.0	-2.3	-1.6	-1.5	-1.7	-1.5	-2.6	-1.4	-0.3
Ever used hormone-replacement therapy (HRT)	3.1	3.9	6.9	0.4	2.3	2.2	-0.1	2.4	2.3	2.4	2.3	1.7	0.9	2.6
Medication: Metformin	3.1	4.3	7.1	2.7	2.0	2.1	2.2	1.8	2.2	1.9	2.1	2.5	1.6	1.5
Diabetes (self-reported)	3.1	4.8	9.2	2.7	1.7	1.9	3.0	1.6	1.8	1.4	1.8	2.7	2.5	2.1
Overall health rating	3.1	6.6	10.8	2.5	3.3	3.0	-1.1	3.0	3.2	3.3	2.7	2.2	-1.5	1.5
Qualifications: A levels/AS levels or equivalent	3.0	6.6	11.3	-1.0	-3.1	-3.2	-0.7	-3.4	-3.2	-2.9	-3.0	-2.7	-1.7	-1.6
Asthma	2.9	5.7	9.4	2.8	2.8	2.9	1.6	2.6	2.6	2.8	2.2	3.1	0.9	-0.4
Alzheimer’s Disease (in mother)	2.8	3.2	4.5	1.7	2.0	2.1	0.6	1.9	2.1	2.1	1.8	2.1	-0.4	-1.9
Long-standing illness, disability or infirmity	2.7	4.2	7.9	2.8	2.2	2.2	1.0	2.4	2.2	2.1	2.2	2.2	0.4	1.6
Asthma (self-reported)	2.7	5.4	9.0	2.5	2.7	2.8	1.7	2.6	2.5	2.7	2.2	3.0	1.1	-0.2
Type 2 Diabetes (T2D) (2012)	2.6	3.0	9.8	0.4	-1.5	-1.2	3.1	-1.7	-1.5	0.0	-0.8	0.1	3.0	2.2
High blood pressure	2.6	7.1	29.7	-0.3	-0.9	-1.3	-5.1	-0.8	-0.6	-0.7	-1.4	-3.1	-5.5	-2.6
Chronic bronchitis/emphysema (father)	2.6	3.0	4.8	2.2	1.5	1.7	2.0	1.6	1.4	1.8	1.4	2.1	1.2	1.7
Medication: Blood pressure	2.6	4.9	13.6	-1.0	-1.7	-1.9	-3.3	-1.6	-1.4	-1.6	-1.6	-2.9	-3.7	-1.8
Angina	2.5	3.3	10.4	-2.4	-1.1	-1.2	-2.0	-1.2	-1.1	-1.1	-1.2	-1.8	-2.2	-3.2
Time employed in main current job	2.5	2.9	5.7	-1.5	-2.0	-2.0	-0.7	-1.8	-2.1	-1.8	-2.4	-1.9	0.1	-0.9
Breastfed as a baby	2.5	3.1	5.5	-1.5	-2.1	-2.1	0.7	-2.2	-2.0	-2.1	-2.3	-1.4	1.2	0.7
Diabetes diagnosed by doctor	2.5	4.1	7.8	2.8	1.7	1.9	2.5	1.7	1.8	1.5	1.6	2.6	2.0	1.5
Heart disease (siblings)	2.5	3.1	6.0	-1.8	-1.6	-1.8	-1.8	-1.3	-1.6	-1.6	-1.9	-2.0	-1.0	-2.5
Ovarian Cancer	2.4	3.1	8.9	3.0	1.3	1.6	2.7	1.2	1.4	1.1	1.9	2.3	0.7	-0.4
Average weekly spirits intake	2.4	2.9	4.9	1.7	1.6	1.8	2.0	1.3	1.6	1.5	2.0	2.2	1.2	1.6
Happiness	2.4	2.9	12.8	0.1	1.3	0.9	-2.4	1.2	1.1	1.5	1.1	-0.2	-3.6	-2.2
Pack years adult smoking proportion	2.3	3.6	6.4	0.4	2.5	2.5	-0.1	2.1	2.5	2.4	2.1	2.1	0.2	0.6
Townsend deprivation index at recruitment	2.3	3.2	5.9	1.0	2.2	2.2	0.1	2.4	2.2	2.2	2.0	1.8	1.1	0.7
Length of working week for main job	2.3	2.5	3.8	0.8	1.9	2.0	0.9	1.8	1.8	1.9	1.6	1.9	1.3	-0.8
Irritable Bowel Disease (IBD)	2.2	5.2	8.6	1.2	2.5	2.6	1.0	2.6	2.9	2.8	2.9	2.5	1.0	1.8
Allergy or Eczema	2.2	5.8	12.5	2.6	2.2	2.4	3.5	1.9	2.0	2.0	2.2	3.3	2.5	1.1
Type 2 Diabetes (T2D) (2018)	2.2	4.2	6.3	2.5	2.0	2.0	2.1	1.9	2.0	1.8	1.8	2.5	1.5	2.1
Diabetes (mother)	2.2	2.8	6.4	0.9	1.8	1.8	0.7	1.9	1.6	1.6	1.1	1.6	2.2	2.5
Age when periods started (menarche)	2.2	5.3	15.7	4.0	1.7	2.0	3.3	2.0	1.9	1.6	2.0	2.9	1.6	0.0
Illness, injury, bereavement, stress in last 2 years	2.2	2.7	4.6	-1.5	-2.0	-1.8	0.7	-2.0	-2.2	-2.1	-1.9	-1.3	1.2	0.2
Mood swings	2.2	4.0	9.5	3.1	2.0	2.0	1.5	2.0	1.9	2.1	2.1	2.3	0.8	1.4
Vascular/heart problems diagnosed by doctor	2.2	6.1	25.8	-0.1	1.0	1.3	4.2	1.0	0.8	0.8	1.4	2.8	5.1	2.9
Allergy	2.1	4.7	8.9	-2.3	-2.4	-2.6	-2.3	-2.2	-2.0	-2.3	-1.8	-3.0	-1.1	1.0
Medication: Ramipril	2.1	2.7	4.4	-1.0	-1.7	-1.7	-1.7	-1.8	-1.5	-1.7	-1.6	-2.1	-1.8	-1.4
Number of children fathered	2.1	2.3	3.5	-1.4	-1.8	-1.9	-0.3	-1.7	-1.9	-1.9	-1.9	-1.6	-0.7	-0.7
Tinnitus: Yes, now most or all of the time	2.1	2.4	3.8	1.8	1.9	1.9	0.4	1.6	2.0	1.7	1.8	1.7	0.7	-0.3
Fractured/broken bones in last 5 years	2.1	2.7	5.8	-1.6	-1.5	-1.6	-2.3	-1.6	-1.1	-1.4	-1.5	-2.4	-1.9	-0.7
Myopia	2.1	3.1	9.1	2.6	0.8	1.0	3.0	0.5	0.3	0.6	0.4	1.8	2.1	2.8
Eye problems/disorders: Diabetes related eye disease	2.0	2.2	3.3	1.8	1.7	1.6	0.8	1.6	1.8	1.5	1.7	1.7	-0.0	0.9
High blood pressure (siblings)	2.0	2.9	15.3	0.7	0.7	0.4	-3.1	1.1	0.8	0.8	0.0	-0.8	-3.9	-1.7
Angina (self-reported)	2.0	2.6	10.0	-2.1	-0.8	-0.9	-1.9	-0.8	-0.8	-0.8	-1.0	-1.4	-2.1	-3.2
Number of live births	1.9	2.7	4.0	1.5	1.9	1.9	1.3	1.9	1.8	1.8	1.7	2.0	1.0	0.9
Medication: Bendroflumethiazide	1.9	2.8	13.4	-0.7	-0.6	-0.8	-2.8	-0.5	-0.3	-0.5	-0.1	-1.6	-3.7	-2.3
Major Depression (MDD)	1.8	2.2	8.7	3.0	0.8	1.1	2.5	0.4	0.7	0.5	1.1	1.7	1.6	-0.4
Frequency of tenseness / restlessness in last 2 weeks	1.8	2.8	4.8	1.9	2.2	2.0	-0.5	1.8	2.0	2.2	1.5	1.6	-1.1	0.6
Guilty feelings	1.8	2.7	5.3	1.4	1.8	1.6	-1.6	1.8	1.7	1.8	1.7	0.7	-2.3	-1.3
Multivitamins +/- minerals	1.7	2.2	4.2	-0.4	-1.9	-1.8	0.6	-2.0	-2.0	-2.1	-1.9	-1.1	0.1	-0.3
High blood pressure (mother)	1.7	2.4	11.6	0.2	0.5	0.3	-3.4	0.7	0.5	0.5	-0.1	-1.2	-3.0	-1.6
Qualifications: None of the above	1.7	3.7	5.3	2.3	2.1	2.2	0.7	2.2	2.0	2.2	1.9	2.1	1.2	1.7
Hair/balding pattern: Pattern 3	1.7	2.5	4.2	1.8	1.9	1.8	0.0	1.7	2.1	1.9	2.0	1.4	-0.3	0.8
Exposure to tobacco smoke at home	1.7	1.9	3.8	-0.7	-1.9	-1.8	0.2	-1.8	-1.6	-2.0	-1.3	-1.4	0.2	-0.3
Gout (self-reported)	1.7	2.4	8.2	-1.5	-0.4	-0.6	-2.9	-0.3	-0.2	-0.2	-0.8	-1.6	-2.5	-2.4
Financial situation satisfaction	1.7	2.1	11.7	-0.8	-1.2	-1.2	-0.8	-1.1	-1.1	-0.9	-1.0	-1.3	-1.0	-3.4
Pack years of smoking	1.7	2.5	4.5	0.4	2.1	2.1	-0.0	1.8	2.1	2.0	1.7	1.8	0.2	0.6
Taking other prescription medications	1.6	2.4	5.2	2.3	1.6	1.6	1.3	1.4	1.3	1.6	1.4	2.0	0.6	1.3
Hair/balding pattern: Pattern 2	1.6	2.0	4.5	-1.0	-1.7	-1.5	0.3	-1.8	-2.0	-1.6	-2.1	-1.2	0.4	-0.3
Commuting to job workplace: Walk	1.6	1.8	4.3	-1.1	-1.2	-1.3	-1.4	-1.6	-1.2	-1.2	-0.4	-1.5	-2.1	-0.9
Medication: Atorvastatin	1.6	2.0	9.4	-0.2	0.3	0.2	-2.3	0.3	0.3	0.4	-0.2	-0.8	-2.4	-3.1
Average weekly beer plus cider intake	1.6	2.4	4.8	-0.3	2.0	1.9	0.1	2.2	1.9	2.1	1.5	1.5	0.9	0.0
Depression (Nagel 2018)	1.5	2.3	4.1	1.3	1.8	1.8	-0.3	1.8	1.9	2.0	1.6	1.3	-0.8	-0.8
Smoking Status	1.5	3.7	6.5	0.8	2.4	2.4	0.2	2.4	2.5	2.5	2.0	2.1	1.0	-0.3
Ever unenthusiastic/disinterested for a whole week	1.5	1.8	3.6	0.6	1.8	1.6	-0.7	1.6	1.6	1.9	1.5	1.2	-0.4	0.5
Frequency of tiredness / lethargy in last 2 weeks	1.5	2.5	3.8	2.0	1.9	1.8	0.3	1.6	1.9	1.8	1.9	1.6	-0.9	0.2
Ever depressed for a whole week	1.5	1.8	3.7	0.8	1.7	1.7	0.1	1.5	1.7	1.8	1.9	1.4	0.1	0.3
Lupus	1.4	2.1	3.8	-1.1	-1.9	-2.0	-0.2	-1.7	-1.5	-1.6	-1.6	-1.6	0.3	1.3
Cardiovascular Disease	1.4	4.7	22.1	1.3	0.8	0.5	-4.4	1.0	1.0	1.2	0.2	-1.3	-4.7	-1.7
Worrier / anxious feelings	1.4	2.6	4.3	1.9	2.1	1.9	-1.1	2.0	1.7	1.9	1.3	1.2	-1.2	0.8
Illnesses of mother	1.4	1.7	7.3	-0.8	-0.5	-0.3	2.0	-0.7	-0.5	-0.5	-0.3	0.5	2.7	2.2
Medication for cholesterol, blood pressure or diabetes	1.4	2.4	12.2	0.7	0.5	0.6	2.6	0.4	0.4	0.3	0.9	1.4	3.5	1.7
Number of full brothers	1.4	1.7	3.5	1.6	1.5	1.5	-0.8	1.9	1.6	1.4	1.2	0.7	-0.6	0.6
Medication: Allopurinol	1.4	1.9	6.7	-1.6	-0.9	-1.1	-2.6	-0.8	-0.7	-0.5	-1.0	-1.8	-1.7	-1.3
Chest pain or discomfort	1.4	2.0	3.7	0.8	1.9	1.8	-0.5	1.8	1.9	1.9	1.5	1.1	-0.3	-0.7
Family relationship satisfaction	1.4	1.8	7.6	0.3	0.7	0.5	-1.9	0.8	0.8	0.9	0.9	-0.3	-2.8	-2.1
Ever had bowel cancer screening	1.4	1.7	2.7	-0.8	-1.2	-1.3	-1.0	-1.3	-1.4	-1.4	-1.6	-1.4	-1.4	-1.0
Respiratory disease	1.3	3.0	4.7	2.0	2.0	2.1	1.1	1.9	1.8	2.1	1.4	2.2	-0.1	-1.0
Other serious medical condition/disability diagnosed by doctor	1.3	1.7	2.3	1.5	1.4	1.4	-0.1	1.5	1.4	1.5	1.5	1.1	-1.2	-1.1
Heel bone mineral density (BMD) T-score, automated (left)	1.3	3.0	18.2	1.1	-0.3	-0.0	4.3	-0.2	-0.3	-0.4	0.4	1.6	3.3	0.1
Birth weight of first child	1.3	2.3	10.4	2.4	0.6	0.8	3.2	0.5	0.4	0.6	0.2	1.9	2.0	0.0
Peak expiratory flow (PEF)	1.3	2.9	5.0	-1.9	-1.6	-1.8	-1.3	-1.7	-2.0	-1.6	-2.2	-2.0	-0.6	-1.2
Medication: Gliclazide	1.3	1.5	4.0	2.0	1.0	1.1	1.2	0.8	1.0	1.0	0.8	1.3	0.8	1.8
HbA1C	1.2	1.4	4.8	-2.2	-0.8	-0.9	-1.2	-0.7	-0.7	-0.7	-1.0	-1.1	-0.2	-2.0
Supplements: Glucosamine	1.2	1.5	7.8	1.2	0.2	0.5	2.8	0.1	0.1	0.1	0.7	1.5	2.1	0.5
Pulse wave reflection index	1.2	1.4	4.9	1.5	0.8	0.9	2.2	0.4	0.7	0.7	0.5	1.5	1.8	0.8
Emphysema/chronic bronchitis	1.2	1.3	2.2	1.1	1.4	1.4	-0.1	1.4	1.4	1.5	0.7	1.0	-0.7	-1.1
Medication: Seretide 50 evohaler	1.2	1.4	2.0	1.4	1.2	1.2	0.6	1.2	1.4	1.3	1.4	1.3	0.1	-1.0
Sensitivity / hurt feelings	1.1	1.9	3.9	2.0	1.5	1.5	0.4	1.5	1.5	1.6	1.4	1.4	-0.4	-0.9
Heel bone mineral density (BMD) T-score, automated (right)	1.1	2.4	13.5	1.3	0.4	0.6	3.7	0.5	0.3	0.4	0.9	1.9	2.4	-0.5
Illnesses of siblings	1.1	1.5	5.0	-0.9	-1.0	-0.8	1.6	-1.4	-0.8	-1.2	-0.4	-0.1	2.2	1.4
Medication: Lansoprazole	1.1	1.3	1.9	0.8	1.1	1.1	1.3	1.1	1.3	0.8	1.4	1.4	0.9	1.0
Mouth/teeth dental problems: Bleeding gums	1.1	1.4	2.4	0.9	1.4	1.2	-0.2	1.4	1.3	1.3	1.1	1.1	1.1	1.6
Alcohol drinker status: Never	1.1	1.3	2.3	-0.6	-1.5	-1.5	-0.0	-1.1	-1.4	-1.5	-1.2	-1.2	0.2	-1.1
Ever had prostate specific antigen (PSA) test	1.1	1.3	2.7	-1.0	-1.1	-1.2	-1.0	-1.2	-1.1	-1.1	-1.4	-1.0	-1.6	0.6
Basal cell carcinoma (self-reported)	1.1	1.3	2.2	-0.7	-1.4	-1.5	-0.7	-1.4	-1.4	-1.4	-1.1	-1.4	-0.2	0.3
Alcohol drinker status: Previous	1.1	1.2	2.0	1.3	1.4	1.3	-0.8	1.4	1.3	1.3	0.9	0.8	-0.2	0.7
Coronary Artery Disease (CAD)	1.0	1.2	2.7	-0.8	-1.3	-1.2	0.1	-1.7	-1.5	0.0	-1.5	-1.0	1.1	0.4
Ever had hysterectomy (womb removed)	1.0	1.1	2.7	-0.6	-1.0	-1.2	-1.6	-0.9	-0.9	-0.9	-1.2	-1.4	-1.0	-0.5
Diabetes (father)	1.0	1.3	4.2	0.5	1.3	1.1	-0.0	1.4	1.1	1.2	0.7	0.8	1.0	2.0
Fed-up feelings	1.0	1.8	4.7	1.7	1.2	1.2	-0.3	1.3	0.9	1.5	0.8	0.8	-1.7	-2.2
Pain all over the body in last month	1.0	1.0	2.1	0.7	1.0	1.1	1.1	0.8	1.0	1.1	0.9	1.4	1.2	0.6
Serious illness, injury or assault of a close relative in last 2 years	1.0	1.2	2.3	0.0	1.2	1.2	-0.6	1.4	1.4	1.1	1.5	0.8	-0.7	1.1
Qualifications: O levels/GCSEs or equivalent	1.0	1.5	3.1	-0.1	-1.5	-1.6	-0.3	-1.8	-1.4	-1.3	-1.3	-1.3	-1.3	-0.3
Chronic bronchitis/emphysema (mother)	1.0	1.1	1.9	-1.0	-1.3	-1.4	-0.6	-1.1	-1.2	-1.3	-1.1	-1.3	-0.3	-0.3
Neck or shoulder pain in last month	1.0	1.4	5.5	-1.2	-0.3	-0.7	-2.3	-0.4	-0.4	-0.4	-1.1	-1.3	-1.9	-0.7
Friendships satisfaction	1.0	1.3	7.5	1.3	0.1	0.1	-1.1	0.2	0.3	0.3	0.5	-0.4	-2.7	-1.8
Medication for cholesterol	1.0	1.5	6.5	0.4	0.5	0.6	2.4	0.4	0.0	0.4	0.3	1.4	2.6	0.7
Osteoporosis (self-reported)	1.0	1.2	2.6	1.5	1.1	1.0	0.3	1.1	1.2	1.0	1.6	1.1	0.1	1.1
Lung FEV1/FVC ratio	0.9	4.3	11.0	-2.8	-1.6	-1.8	-3.3	-1.6	-1.6	-1.6	-1.4	-2.9	-2.2	0.1
Chronotype (morning person)	0.9	2.0	9.9	-1.6	0.8	1.0	1.8	0.8	1.0	0.6	0.8	1.4	3.1	0.9
Heart attack	0.9	1.1	1.6	-0.2	-1.0	-1.0	-1.0	-1.0	-1.1	-1.0	-1.2	-1.3	-1.2	-1.2
Mouth/teeth dental problems: Mouth ulcers	0.9	1.5	4.3	-0.1	-0.9	-1.1	-1.4	-0.8	-0.8	-0.9	-1.2	-1.4	-2.1	-1.7
Ever taken oral contraceptive pill	0.9	1.0	2.1	0.8	0.7	0.8	1.5	0.7	0.6	0.7	1.0	1.2	0.9	1.4
Commuting to job workplace: Public transport	0.9	1.1	2.3	0.0	-1.4	-1.2	0.4	-1.5	-1.3	-1.5	-0.8	-0.8	-0.3	0.8
Medication: Lisinopril	0.9	1.2	6.1	1.2	0.4	0.3	-2.0	0.4	0.3	0.5	-0.1	-0.6	-2.5	-0.4
Depressed Affect (Nagel 2018)	0.8	1.6	6.1	2.5	1.1	1.1	1.1	1.0	0.9	1.1	1.2	1.5	-0.8	-1.0
Verbal and Numeric Reasoning (VNR)	0.8	2.0	2.9	-0.9	-1.3	-1.5	-0.9	-1.5	-1.4	-1.5	-1.3	-1.6	-1.5	-1.7
Age at First Birth	0.8	1.2	2.6	0.4	-1.3	-1.3	1.1	-1.6	-1.4	-1.4	-1.1	-0.6	-0.1	0.0
Relative age of first facial hair	0.8	1.6	5.9	-0.8	1.4	1.2	-1.0	1.2	1.3	1.5	0.8	0.9	0.2	-2.4
Hayfever, allergic rhinitis or eczema	0.8	1.8	4.4	1.2	1.3	1.4	2.1	1.0	1.1	1.1	1.0	2.0	1.2	-0.4
Hayfever/allergic rhinitis (self-reported)	0.8	1.1	6.9	0.4	-0.1	0.0	2.6	-0.3	-0.0	-0.0	0.5	1.0	1.1	-1.6
Neuroticism score	0.8	1.6	4.6	1.5	1.1	0.9	-1.2	1.2	0.8	1.2	0.5	0.4	-2.1	-1.8
Father’s age at death	0.8	1.1	4.9	0.7	-0.3	-0.2	2.2	-0.2	-0.4	-0.4	0.2	0.6	1.9	1.5
Medication: Cholesterol lowering	0.8	1.2	4.5	-1.1	-0.7	-0.8	-0.7	-0.7	-0.7	-0.8	-1.2	-0.8	-1.5	-2.1
Health satisfaction	0.8	1.0	1.6	-0.2	1.3	1.0	-1.2	1.2	1.2	1.3	1.0	0.5	-0.4	-0.9
Knee pain experienced in last month	0.8	1.2	3.9	1.6	0.9	0.9	0.1	0.9	1.0	1.1	1.1	0.8	0.3	2.0
Osteoarthritis (self-reported)	0.8	1.0	2.3	-0.4	1.3	1.2	-0.3	1.5	1.0	1.5	0.9	0.9	0.3	0.6
Risk taking	0.8	1.2	3.8	1.8	0.6	0.8	1.9	0.6	0.8	0.6	0.9	1.3	0.7	0.7
Pain experienced in last month	0.8	1.3	5.9	-2.4	-0.7	-0.7	-0.1	-0.6	-0.9	-0.7	-0.7	-0.7	0.4	-2.1
Prostate Cancer	0.7	1.0	3.8	-1.8	-0.4	-0.5	-1.9	-0.4	-0.6	-0.5	-1.1	-1.3	-0.4	-0.3
Body Mass Index (BMI) (2010)	0.7	0.9	1.8	-0.1	1.1	0.9	-1.3	1.3	1.1	1.1	0.9	0.3	-1.0	-0.3
Triglycerides	0.7	1.1	3.9	0.6	-0.2	-0.1	1.9	-0.5	-0.2	-0.3	0.2	0.7	2.0	1.8
Blood Red Count	0.7	6.6	19.4	2.1	1.6	2.0	4.0	1.4	1.6	1.7	1.9	3.0	4.4	2.4
Average weekly fortified wine intake	0.7	0.9	2.3	1.1	0.7	0.6	-0.5	0.8	1.0	0.9	0.7	0.3	-1.5	1.4
Maternal smoking around birth	0.7	1.1	2.9	-0.9	-0.5	-0.7	-1.4	-0.4	-0.6	-0.3	-0.9	-1.0	-1.7	-1.7
Qualifications: CSEs or equivalent	0.7	0.9	2.7	0.3	0.7	0.8	0.9	1.0	0.9	0.9	0.9	0.9	1.6	0.9
Serious illness, injury or assault to yourself	0.7	0.9	3.2	0.6	0.5	0.2	-1.8	0.3	0.5	0.5	0.2	-0.4	-1.8	-1.3
Stomach or abdominal pain in last month	0.7	0.8	3.4	1.8	0.8	0.7	0.5	0.5	0.7	0.7	0.7	0.7	-0.3	1.5
Diverticular disease/diverticulitis (self-reported)	0.7	0.8	2.8	0.9	0.4	0.6	1.7	0.2	0.5	0.3	0.5	1.0	1.4	1.1
Depression (self-reported)	0.7	0.9	4.1	2.0	0.9	1.0	0.8	0.7	0.7	0.9	0.3	1.0	-0.1	-0.2
Prospective memory result	0.7	0.8	2.1	0.5	0.6	0.8	1.5	0.6	0.8	0.6	1.1	1.2	1.4	0.0
Forced expiratory volume in 1-second (FEV1), Best measure	0.7	2.1	5.7	-1.0	-1.3	-1.4	-1.2	-1.3	-1.5	-1.3	-1.6	-1.6	-0.9	-2.4
Pulse wave Arterial Stiffness index	0.7	0.8	1.6	-0.6	-0.9	-0.9	0.7	-1.3	-1.0	-1.0	-0.8	-0.4	1.0	0.9
Seen doctor (GP) for nerves, anxiety, tension or depression	0.7	1.1	4.4	0.3	-0.6	-0.7	-1.1	-0.7	-1.0	-0.7	-1.4	-1.0	-2.1	-0.9
Pulse wave peak to peak time	0.7	0.8	1.8	0.7	1.0	1.0	-0.5	1.4	1.1	1.1	1.0	0.6	-0.7	-0.9
Pulse rate, automated reading	0.7	2.4	3.6	-0.8	1.9	1.8	-1.3	1.7	1.9	1.9	1.6	1.0	-0.3	1.8
Suffer from ‘nerves’	0.7	1.0	4.9	-0.3	0.4	0.2	-1.9	0.5	0.0	0.5	-0.7	-0.5	-2.2	-1.1
Illnesses of father: Heart disease	0.7	1.0	1.5	-0.3	-1.0	-1.1	-0.9	-1.2	-1.0	-1.1	-1.1	-1.2	-1.0	-0.1
Arm fat percentage (left)	0.7	2.6	6.0	-2.4	-1.7	-1.7	-1.9	-1.5	-1.3	-1.4	-1.6	-2.2	-0.5	-0.2
Eye problems/disorders: Cataract	0.7	0.8	2.8	1.7	-0.0	0.1	1.3	0.0	-0.0	-0.0	-0.0	0.8	1.3	1.4
Number of operations (self-reported)	0.7	1.0	2.9	-1.1	-0.6	-0.7	-1.6	-0.6	-0.5	-0.4	-0.7	-1.1	-1.7	-0.8
Neuroticism (Nagel 2018)	0.6	1.4	3.7	1.9	1.2	1.1	-0.1	1.0	0.8	1.2	0.9	1.0	-1.5	-1.3
Worry (Nagel 2018)	0.6	1.3	6.5	0.2	0.1	-0.1	-2.2	0.1	-0.3	0.2	-0.9	-0.8	-2.5	-1.2
Crohns Disease (2017)	0.6	1.2	2.5	0.6	1.3	1.3	0.1	1.4	1.6	1.5	1.3	1.2	-0.4	0.3
Fasting Glucose	0.6	0.7	1.4	-0.5	-0.9	-0.9	0.1	-1.1	-1.1	-1.1	-1.2	-0.7	-0.4	0.2
Neuroticism (2016)	0.6	0.9	1.6	1.0	0.9	0.7	-1.0	1.0	0.9	1.2	0.8	0.4	-1.3	-1.1
Blood Eosinophil Count	0.6	4.3	7.3	1.4	2.1	2.2	1.6	2.2	2.2	2.3	1.9	2.5	2.7	0.9
Neuroticism	0.6	1.5	6.9	1.9	0.8	0.8	-0.4	0.7	0.5	0.9	0.3	0.6	-1.8	-2.6
Arm fat percentage (right)	0.6	2.4	5.7	-2.4	-1.6	-1.6	-1.9	-1.4	-1.3	-1.3	-1.6	-2.1	-0.4	-0.1
Falls in the last year	0.6	0.8	2.6	1.6	0.1	0.2	1.2	-0.0	0.1	0.2	0.5	0.5	1.1	1.6
Exposure to tobacco smoke outside home	0.6	0.8	1.3	1.1	0.8	0.8	1.2	0.7	0.9	0.9	0.9	1.1	0.4	0.5
Mineral and other dietary supplements	0.6	0.8	3.3	-0.6	-0.6	-0.7	-1.8	-0.4	-0.3	-0.4	-0.6	-1.4	-1.3	0.0
Illnesses of father: None of the above (group 1)	0.6	0.8	3.3	0.6	0.2	0.5	1.8	0.1	0.3	0.1	0.7	1.1	1.8	0.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.6	1.3	2.0	-0.5	-1.2	-1.2	-0.7	-1.4	-1.4	-1.3	-1.4	-1.4	-0.2	-0.9
Miserableness	0.6	1.1	6.0	2.4	0.6	0.7	1.2	0.6	0.5	0.7	0.6	1.0	-0.8	-0.8
Cholesterol lowering medication	0.6	0.8	2.1	1.5	0.7	0.7	-0.7	0.7	0.8	0.7	1.1	0.3	-0.6	1.4
Heart attack/myocardial infarction (self-reported)	0.6	0.7	1.3	-0.1	-0.8	-0.8	-0.8	-0.8	-0.9	-0.8	-0.9	-1.0	-1.1	-1.1
Primary Biliary Cirrhosis	0.5	0.7	2.7	0.2	-0.6	-0.5	1.6	-0.6	-0.4	-0.6	0.0	0.2	1.5	1.2
Medication for hormone replacement therapy	0.5	0.6	1.3	-0.2	1.0	0.9	-0.3	1.0	1.1	1.1	0.6	0.7	-0.3	0.2
Had other major operations	0.5	0.6	2.0	0.6	0.3	0.3	1.2	0.0	0.1	0.4	0.2	0.9	1.4	1.2
Pulse rate	0.5	0.9	4.4	-1.6	0.7	0.5	-2.1	0.6	0.7	0.7	0.5	-0.2	-0.8	0.5
Impedance of arm (left)	0.5	2.5	7.3	-2.7	-1.6	-1.8	-1.7	-1.6	-1.1	-1.6	-0.9	-1.8	-0.7	-0.6
Tense / ‘highly strung’	0.5	0.9	3.8	-0.1	0.6	0.3	-1.9	0.6	0.3	0.8	-0.4	-0.2	-2.0	-0.6
Loud music exposure frequency	0.5	0.6	4.2	0.2	-0.2	-0.1	1.3	-0.3	-0.0	-0.1	0.1	0.4	2.0	-0.2
Medication: Paracetamol	0.5	0.8	3.5	1.5	-0.6	-0.4	1.9	-0.6	-0.5	-0.6	-0.5	0.3	0.4	1.0
Worry too long after embarrassment	0.5	0.9	1.8	0.4	1.1	1.0	0.1	1.2	1.1	1.0	0.9	0.9	0.0	-1.3
Seen a psychiatrist for nerves, anxiety, tension or depression	0.5	0.6	2.5	1.6	0.6	0.6	0.0	0.6	0.5	0.6	-0.0	0.7	-1.3	-0.4
Qualifications: College or University degree	0.5	1.5	3.5	-0.8	-1.3	-1.3	-0.7	-1.5	-1.2	-1.2	-0.7	-1.2	-1.4	-1.9
Medication for pain relief, constipation, heartburn	0.5	0.9	2.0	-0.6	1.1	0.9	-1.4	1.4	1.1	1.1	0.9	0.3	0.1	-0.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.5	0.6	3.2	-1.6	-0.1	-0.3	-0.5	-0.1	-0.1	0.0	-0.2	-0.3	0.8	-1.8
Alcohol intake frequency.	0.5	1.2	2.4	0.4	-1.3	-1.3	-1.2	-0.9	-1.2	-1.3	-1.6	-1.5	-0.2	-0.5
Comparative height size at age 10	0.5	2.8	5.5	-0.6	-2.0	-2.0	0.9	-2.4	-2.0	-2.2	-1.5	-1.2	1.7	0.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.5	0.6	2.1	-1.4	-0.4	-0.6	-1.1	-0.6	-0.6	-0.2	-0.9	-0.8	-0.0	0.6
Number of self-reported non-cancer illnesses	0.5	1.0	4.0	2.0	0.9	1.0	0.5	0.9	0.7	1.0	0.5	1.1	-0.4	-0.5
Average weekly champagne plus white wine intake	0.5	0.6	1.2	0.4	0.9	0.9	-0.8	1.0	1.0	0.9	0.5	0.4	-0.5	-1.1
Wears glasses or contact lenses	0.5	0.6	3.7	-0.1	-0.5	-0.5	0.2	-0.6	-0.7	-0.7	-0.2	-0.3	0.6	1.9
Pain type(s) experienced in last month: Hip pain	0.5	0.6	4.8	-0.5	-0.4	-0.4	-0.7	-0.2	-0.2	-0.3	-0.3	-0.6	0.6	2.2
Medication: Omeprazole (e.g. Zanprol)	0.5	0.6	1.4	0.9	0.9	0.8	0.1	0.7	0.8	1.2	0.7	0.7	-0.5	-0.6
Bipolar Disorder (2018)	0.4	0.7	3.1	1.8	0.0	0.1	0.9	-0.0	-0.0	0.3	-0.2	0.5	-0.4	-1.6
Bipolar Disorder (2011)	0.4	0.4	0.7	0.7	-0.8	-0.7	0.6	-0.8	-0.8	0.0	-0.8	-0.4	0.2	-0.5
Mean Putamen Volume	0.4	0.5	1.4	-0.2	0.8	0.7	-0.0	0.7	0.8	0.7	1.2	0.6	0.3	0.8
Rheumatoid Arthritis	0.4	0.6	1.1	-0.5	-0.8	-0.7	0.7	-1.1	-1.0	-0.9	-1.0	-0.4	0.2	-0.9
Waist Hip Ratio (WHR)	0.4	1.8	6.8	2.6	1.1	1.1	-0.7	0.7	1.1	1.2	1.3	0.6	-0.2	2.3
Vitamin and mineral supplements	0.4	0.5	0.9	-0.3	0.7	0.7	-0.6	0.8	1.0	0.9	0.8	0.3	-0.3	-0.7
Trunk fat percentage	0.4	1.6	4.7	-2.2	-1.4	-1.4	-1.0	-1.2	-1.0	-1.1	-0.9	-1.5	0.9	0.9
Number of incorrect matches in round	0.4	0.7	1.5	1.2	0.5	0.6	0.9	0.7	0.9	0.7	1.1	0.8	0.7	0.5
Impedance of arm (right)	0.4	1.8	5.6	-2.4	-1.2	-1.4	-1.7	-1.4	-1.0	-1.2	-0.7	-1.5	-0.8	-0.5
Forced expiratory volume in 1-second (FEV1)	0.4	1.4	2.9	-0.3	-1.2	-1.2	-0.2	-1.4	-1.5	-1.3	-1.5	-1.1	-0.6	-1.7
Standing height	0.4	3.5	17.6	1.7	-0.3	0.1	4.2	-0.5	-0.0	-0.5	0.9	1.8	3.6	1.0
Arm fat-free mass (right)	0.4	2.0	8.2	1.8	0.2	0.6	2.9	0.4	0.3	0.3	0.6	1.3	2.5	1.1
Comparative body size at age 10	0.4	1.0	2.4	-1.5	-0.7	-0.7	-1.5	-0.7	-0.9	-0.5	-1.3	-1.2	-0.0	0.9
Medication: Omeprazole	0.4	0.4	1.4	1.2	0.7	0.7	0.3	0.6	0.6	1.0	0.4	0.6	-0.5	-0.3
Heart disease (mother)	0.4	0.5	1.3	1.1	0.7	0.7	-0.1	0.7	0.8	0.4	0.7	0.6	0.5	0.6
Arm predicted mass (right)	0.4	1.9	7.0	1.9	0.4	0.7	2.6	0.6	0.5	0.6	0.7	1.4	2.3	1.1
Number of full sisters	0.4	0.5	3.1	0.6	-0.4	-0.2	1.8	-0.2	-0.4	-0.4	-0.0	0.5	0.9	0.6
Age at last live birth	0.4	0.6	3.8	2.0	-0.2	-0.2	0.5	-0.1	0.1	-0.1	0.6	0.0	-1.4	-0.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.4	0.5	1.0	0.5	0.5	0.5	1.0	0.7	0.5	0.6	0.7	0.7	0.9	0.9
Ever had stillbirth, spontaneous miscarriage or termination	0.4	0.5	1.7	1.3	0.7	0.6	0.7	0.8	0.5	0.5	0.6	0.8	-0.2	-0.1
Supplements: Fish oil (including cod liver oil)	0.4	0.5	2.6	0.0	0.2	0.3	1.6	-0.1	-0.1	-0.0	0.1	1.0	1.3	-0.6
High cholesterol (Self-reported)	0.4	0.7	1.4	0.5	1.0	1.1	-0.0	1.0	0.9	1.2	0.8	0.9	-0.3	-0.3
Medication: Paracetamol	0.4	0.6	2.2	1.5	-0.5	-0.4	1.3	-0.7	-0.5	-0.6	-0.5	0.1	-0.4	0.7
Ever smoked	0.4	0.7	1.4	-0.1	1.1	1.0	0.2	1.1	1.0	1.2	0.6	0.9	0.5	0.5
Commuting to job workplace: Cycle	0.4	0.5	1.7	1.1	0.3	0.3	1.3	0.1	0.7	0.3	0.8	0.5	0.9	0.9
Bipolar Disorder or Schizophrenia	0.3	0.7	2.4	1.5	-0.2	-0.1	1.5	-0.2	-0.3	-0.0	-0.3	0.4	1.1	-1.3
Intelligence (Savage-Jansen 2018)	0.3	0.9	4.1	-0.0	-0.6	-0.7	-0.5	-0.8	-0.8	-0.8	-0.6	-0.7	-1.3	-2.0
Breast Cancer	0.3	0.8	2.9	-0.4	1.2	0.9	-1.7	0.8	1.2	0.9	0.3	0.3	-0.4	0.4
Height	0.3	5.8	20.2	1.1	-2.1	-1.6	4.3	-2.2	-1.9	-2.4	-0.7	0.3	4.5	1.4
Hand grip strength (left)	0.3	0.7	2.8	0.8	-0.6	-0.5	1.4	-0.4	-0.8	-0.7	-0.4	0.0	1.7	0.4
Hearing difficulty/problems: Yes	0.3	0.5	3.2	-0.7	-0.1	-0.2	-0.9	-0.2	-0.0	0.0	-0.1	-0.5	0.7	1.8
Bilateral oophorectomy (both ovaries removed)	0.3	0.3	1.3	-0.5	-0.0	-0.1	-1.1	0.0	-0.1	0.1	-0.5	-0.5	-0.6	1.1
Impedance of leg (left)	0.3	1.6	4.6	-0.8	1.0	1.0	0.5	1.0	1.1	0.8	1.5	1.2	2.2	2.0
Alcohol usually taken with meals	0.3	0.4	1.9	0.3	-0.4	-0.3	1.3	-0.4	-0.3	-0.5	-0.1	0.3	1.4	0.7
Had menopause	0.3	0.4	1.8	-0.3	0.5	0.5	-0.5	0.5	0.5	0.6	0.7	0.2	0.5	1.3
Fluid intelligence score	0.3	0.5	2.5	-0.7	-0.3	-0.5	-0.8	-0.3	-0.4	-0.5	-0.4	-0.7	-0.7	-1.6
Mouth/teeth dental problems: Dentures	0.3	0.6	1.7	0.5	0.8	0.8	-0.1	0.7	0.8	0.7	0.8	0.6	0.4	1.3
Medication: Ibuprofen (e.g. Nurofen)	0.3	0.4	1.8	-0.2	-0.5	-0.5	1.3	-0.7	-0.7	-0.8	-0.4	0.2	0.7	-0.3
Blood clot in the leg (DVT)	0.3	0.4	0.9	0.1	0.7	0.8	0.3	0.9	0.4	0.9	0.4	0.8	-0.1	-0.1
Birth weight	0.3	0.7	3.0	1.0	0.1	0.3	1.7	0.2	-0.5	-0.1	-0.6	0.9	1.3	0.9
Body fat percentage	0.3	1.3	4.5	-2.1	-1.0	-1.0	-1.2	-0.7	-0.7	-0.7	-0.8	-1.3	0.8	1.1
Reason for reducing amount of alcohol drunk: Health precaution	0.3	0.3	0.6	-0.4	0.7	0.7	0.0	0.7	0.7	0.5	0.7	0.6	0.6	0.2
Age at first live birth	0.3	0.5	1.0	0.0	-1.0	-1.0	0.2	-1.0	-0.8	-0.9	-0.5	-0.8	0.1	-0.5
Shortness of breath walking on level ground	0.3	0.3	2.5	-0.3	0.3	0.2	-0.7	-0.1	0.3	0.3	0.1	-0.3	0.2	-1.6
Migraine (self-reported)	0.3	0.4	1.1	0.4	0.7	0.6	0.1	0.5	0.9	0.7	1.0	0.6	-0.5	0.5
Qualifications: NVQ or HND or HNC or equivalent	0.3	0.3	2.2	0.2	-0.4	-0.2	0.4	-0.3	-0.3	-0.5	-0.3	-0.1	-0.5	1.5
Commuting to job workplace: Car/motor vehicle	0.3	0.3	0.7	0.4	0.5	0.5	0.5	0.8	0.5	0.5	0.0	0.6	0.8	0.5
Medication: Aspirin	0.3	0.3	1.1	0.5	-0.5	-0.5	0.8	-0.9	-0.5	-0.5	-0.3	-0.2	-0.1	-1.0
Smoking status: Previous	0.3	0.4	0.7	-0.8	-0.6	-0.7	-0.7	-0.4	-0.5	-0.5	-0.9	-0.8	-0.7	-0.4
Forced expiratory volume in 1-second (FEV1), predicted	0.3	0.7	3.8	-0.4	0.6	0.6	0.5	0.8	0.7	0.6	0.5	0.7	1.9	0.8
Medication: Aspirin	0.3	0.3	0.9	0.5	-0.6	-0.5	0.9	-1.0	-0.6	-0.6	-0.3	-0.2	0.3	-0.3
Arm fat mass (left)	0.3	1.1	1.7	-1.3	-1.3	-1.2	-0.5	-1.1	-1.0	-1.0	-1.1	-1.3	0.6	0.5
Hearing aid user	0.3	0.3	1.6	-1.3	0.1	-0.1	-1.2	0.2	-0.1	0.1	-0.5	-0.5	-0.5	-0.0
Arm fat-free mass (left)	0.3	1.4	5.9	1.7	0.2	0.4	2.4	0.3	0.1	0.3	0.3	1.1	2.0	0.8
Diastolic blood pressure, automated reading	0.3	0.9	3.1	1.8	0.9	0.8	-0.4	0.9	0.9	0.8	0.3	0.5	0.2	1.7
Arm predicted mass (left)	0.3	1.5	6.7	1.5	-0.1	0.2	2.6	-0.0	-0.1	0.0	0.2	0.9	2.3	0.9
Schizophrenia (2018)	0.2	0.5	2.9	0.6	-0.2	-0.2	1.2	-0.3	-0.4	-0.3	-0.2	0.2	1.7	-0.5
Schizophrenia vs Biploar Disorder	0.2	0.3	1.8	-0.8	0.0	-0.0	-0.5	-0.2	-0.1	0.0	-0.1	-0.2	0.4	1.3
Schizophrenia (2014)	0.2	0.4	2.1	0.4	-0.2	-0.2	1.4	-0.4	-0.3	-0.1	-0.1	0.4	1.5	-0.5
Severe depression (siblings)	0.2	0.2	0.8	0.5	0.3	0.3	0.2	0.5	0.3	0.3	0.3	0.4	0.2	0.9
Impedance of leg (right)	0.2	1.1	3.3	-1.1	0.9	0.8	-0.2	0.9	1.0	0.7	1.3	0.7	1.4	1.8
Hand grip strength (right)	0.2	0.6	2.4	1.1	0.2	0.3	1.5	0.4	0.0	0.2	0.3	0.8	1.4	0.4
Medication: Levothyroxine sodium	0.2	0.3	1.3	-0.0	-0.2	-0.2	0.0	-0.3	-0.5	-0.1	-1.1	-0.1	-0.8	-0.9
Sitting height	0.2	1.2	5.3	0.8	0.1	0.3	2.3	-0.0	0.5	0.1	0.8	1.2	2.2	-0.2
Trunk fat mass	0.2	0.7	2.0	-1.2	-0.9	-0.8	-0.0	-0.7	-0.6	-0.7	-0.5	-0.7	1.4	1.0
Nervous feelings	0.2	0.4	1.8	-0.7	0.2	0.0	-1.1	0.3	-0.1	0.2	-0.4	-0.2	-1.3	-0.2
Mouth/teeth dental problems	0.2	0.3	1.4	0.5	-0.3	-0.2	1.1	-0.4	-0.5	-0.3	0.0	0.2	-0.2	-1.2
Trunk fat-free mass	0.2	1.2	6.9	1.5	-0.1	0.2	2.6	-0.1	-0.2	-0.1	0.1	1.0	1.8	0.2
Alcohol intake versus 10 years previously	0.2	0.3	2.0	0.5	-0.1	-0.1	-1.4	0.2	0.1	-0.0	-0.4	-0.7	-0.3	0.6
Lung cancer (father)	0.2	0.3	0.5	0.7	0.4	0.4	0.6	0.4	0.5	0.4	0.5	0.6	0.7	0.2
Arm fat mass (right)	0.2	1.0	1.5	-1.2	-1.2	-1.2	-0.6	-1.0	-1.0	-0.9	-1.1	-1.2	0.5	0.5
Trunk predicted mass	0.2	1.1	6.6	1.5	-0.2	0.1	2.6	-0.1	-0.3	-0.1	-0.0	0.9	1.6	0.0
Headache pain in last month	0.2	0.3	1.5	1.2	0.1	0.2	0.9	0.0	0.1	0.0	0.4	0.5	-0.1	1.0
Forced vital capacity (FVC), Best measure	0.2	0.6	5.5	0.2	-0.2	-0.2	0.6	-0.3	-0.4	-0.3	-0.5	0.2	0.2	-2.4
Leg fat percentage (right)	0.2	0.7	3.5	-1.2	0.2	0.2	-0.8	0.6	0.4	0.4	0.2	-0.2	1.0	1.9
Medication: Ibuprofen	0.2	0.2	1.5	-0.2	-0.1	-0.1	1.2	-0.2	-0.4	-0.3	-0.2	0.5	0.6	-0.6
Leg pain on walking	0.2	0.3	1.8	0.5	-0.0	0.1	0.8	-0.0	0.2	0.1	0.2	0.3	1.3	0.6
Whole body fat-free mass	0.2	1.0	5.3	1.4	-0.3	-0.0	2.3	-0.2	-0.3	-0.2	-0.1	0.7	1.7	0.3
Leg fat-free mass (right)	0.2	0.9	3.1	1.0	-0.9	-0.7	1.8	-0.9	-0.8	-0.8	-0.6	-0.1	1.2	-0.2
Handedness (chirality/laterality): Left-handed	0.2	0.2	0.6	-0.8	-0.3	-0.3	-0.8	-0.0	-0.1	-0.4	-0.3	-0.7	0.3	0.5
Back pain experienced in last month	0.2	0.3	1.0	0.9	-0.0	-0.2	-0.7	-0.1	-0.1	0.0	-0.4	-0.4	-1.0	0.5
Breast cancer (self-reported)	0.2	0.2	0.7	0.1	-0.6	-0.5	0.2	-0.6	-0.5	-0.8	-0.2	-0.4	0.4	0.3
Whole body water mass	0.2	0.9	5.2	1.4	-0.4	-0.1	2.3	-0.3	-0.4	-0.3	-0.1	0.6	1.6	0.2
Leg predicted mass (right)	0.2	0.8	2.9	1.0	-0.9	-0.7	1.7	-0.8	-0.8	-0.8	-0.6	-0.1	1.1	-0.3
Mother’s age at death	0.2	0.3	0.7	0.6	0.5	0.6	0.8	0.2	0.5	0.3	0.6	0.7	0.1	-0.1
Basal metabolic rate	0.2	0.9	4.3	1.0	-0.5	-0.3	2.1	-0.4	-0.4	-0.4	-0.2	0.4	1.7	0.3
Leg fat percentage (left)	0.2	0.7	3.3	-1.0	0.3	0.3	-0.3	0.6	0.4	0.4	0.3	0.0	1.3	1.8
Age started oral contraceptive pill	0.2	0.2	0.5	0.1	-0.7	-0.6	0.3	-0.6	-0.7	-0.5	0.1	-0.3	0.4	0.4
Supplements: Calcium	0.2	0.2	0.4	0.1	-0.6	-0.6	-0.0	-0.6	-0.4	-0.6	-0.4	-0.3	0.1	0.0
Deep venous thrombosis (DVT) (self-reported)	0.2	0.3	0.7	0.4	0.6	0.7	0.2	0.8	0.4	0.7	0.3	0.7	-0.3	-0.1
Leg fat mass (left)	0.2	0.6	3.1	-0.2	0.1	0.2	0.6	0.4	0.2	0.3	0.2	0.3	1.8	1.7
Reaction Time	0.1	0.3	1.1	1.0	0.3	0.5	0.5	0.4	0.3	0.3	0.7	0.5	-0.0	-0.2
Crohns Disease (2012)	0.1	0.2	0.7	-0.2	0.4	0.4	-0.8	0.4	0.5	0.0	0.2	0.0	-0.7	0.2
LDL Cholesterol	0.1	0.2	0.9	0.2	0.4	0.4	0.4	0.4	0.1	0.3	0.1	0.5	0.6	0.9
Blood White Count	0.1	0.5	1.6	-0.9	-0.3	-0.5	-1.3	-0.0	-0.3	-0.1	-0.5	-0.8	-0.9	-1.2
BMI	0.1	0.3	1.0	-0.3	-0.3	-0.4	-1.0	0.1	-0.3	0.0	-1.0	-0.7	-0.5	-0.6
Hypothyroidism (self reported)	0.1	0.3	1.0	-0.1	-0.3	-0.2	0.5	-0.6	-0.4	-0.2	-1.0	0.0	0.4	-1.0
Lung FVC	0.1	0.6	2.6	1.3	0.2	0.3	1.6	-0.1	-0.3	-0.0	-0.4	0.9	0.9	-0.3
Tanning	0.1	1.6	7.3	1.1	0.4	0.6	2.3	0.2	0.4	0.2	0.5	1.4	2.7	0.7
Number of treatments/medications taken	0.1	0.2	1.0	1.0	-0.1	-0.1	0.3	-0.4	-0.1	-0.1	-0.0	0.2	-1.0	0.2
Leg fat-free mass (left)	0.1	0.7	2.2	0.8	-0.9	-0.8	1.5	-0.8	-0.9	-0.8	-0.7	-0.2	1.1	0.1
Relative age voice broke	0.1	0.2	0.7	-0.9	-0.3	-0.4	-0.2	-0.2	-0.4	-0.3	-0.0	-0.2	-0.1	-0.6
Tinnitus: Yes, but not now, but have in the past	0.1	0.1	0.2	0.0	0.4	0.4	-0.2	0.5	0.3	0.4	-0.1	0.2	0.2	-0.2
Body mass index (BMI)	0.1	0.5	1.1	-0.9	-0.7	-0.6	-0.9	-0.4	-0.6	-0.4	-1.0	-1.1	0.0	0.2
Leg predicted mass (left)	0.1	0.7	1.9	0.8	-0.9	-0.8	1.4	-0.8	-0.8	-0.8	-0.7	-0.2	1.0	-0.0
Waist circumference	0.1	0.3	1.8	0.8	-0.4	-0.3	0.2	-0.5	-0.3	-0.2	-0.3	-0.2	0.6	1.4
Hearing difficulty/problems with background noise	0.1	0.1	0.4	0.2	-0.4	-0.3	0.0	-0.4	-0.2	-0.3	-0.5	-0.3	0.6	0.6
Forced vital capacity (FVC)	0.1	0.5	1.8	0.7	-0.2	-0.1	1.3	-0.4	-0.4	-0.3	-0.3	0.5	0.3	-1.3
Medication: Simvastatin	0.1	0.1	0.8	0.2	0.0	0.0	-0.0	-0.0	-0.1	-0.0	-0.2	0.1	-0.9	0.5
Weight	0.1	0.5	2.6	-0.0	-0.7	-0.5	1.0	-0.5	-0.5	-0.5	-0.5	-0.1	1.6	0.6
Hip circumference	0.1	0.5	1.1	-0.4	-1.0	-0.9	0.5	-0.9	-0.8	-0.8	-0.8	-0.6	0.6	-0.2
Noisy workplace	0.1	0.2	0.8	-0.9	-0.3	-0.3	-0.4	-0.1	-0.3	-0.3	-0.4	-0.5	0.3	0.3
Hypothyroidism/myxoedema (self-reported)	0.1	0.1	0.5	0.6	0.1	0.1	0.7	-0.2	-0.1	0.2	-0.5	0.4	-0.0	-0.4
Mean time to correctly identify matches	0.1	0.2	1.0	1.0	0.2	0.3	0.3	0.3	0.2	0.1	0.5	0.3	0.1	0.2
Whole body fat mass	0.1	0.5	1.5	-0.9	-0.7	-0.6	-0.2	-0.4	-0.4	-0.5	-0.4	-0.6	1.2	1.2
Leg fat mass (right)	0.1	0.5	2.6	-0.2	0.1	0.3	0.4	0.4	0.3	0.3	0.2	0.2	1.6	1.6
Supplements: Vitamin C	0.1	0.1	0.7	-0.6	0.1	-0.0	-0.4	0.1	0.1	-0.0	-0.0	-0.1	0.4	0.8
Qualifications: nursing, teaching	0.1	0.2	0.5	-0.0	-0.6	-0.7	-0.2	-0.7	-0.4	-0.7	0.1	-0.6	-0.2	-0.2
Irritability	0.1	0.2	1.0	0.1	0.3	0.1	-1.0	0.1	0.1	0.4	0.3	-0.1	-1.0	-0.3
Impedance of whole body	0.1	0.5	3.5	-1.9	-0.4	-0.5	-0.7	-0.5	-0.0	-0.5	0.4	-0.4	0.5	0.6
Blood Platelet Count	0.0	0.4	2.7	-0.7	0.3	0.1	-0.2	0.6	-0.1	0.6	-0.3	0.0	1.6	0.7
Hair Pigment	0.0	0.3	1.1	-0.9	-0.3	-0.3	-0.3	-0.1	-0.5	-0.1	-1.0	-0.5	0.6	-0.4
Past tobacco smoking	0.0	0.0	0.2	0.4	-0.1	0.0	0.0	-0.2	-0.0	-0.2	0.3	0.0	-0.1	0.2
Hair/balding pattern: Pattern 4	0.0	0.1	0.6	-0.6	0.0	0.0	0.3	0.2	-0.1	-0.1	0.2	0.0	0.8	0.3

Hub : Genes

BICC1

Models

Trait associations