[Hub]/) : Traits : Heel T-Score : ← →

chr10:133,309,117-135,295,396

Best TWAS P=3.84e-15 · Best GWAS P=6.79e-43 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	DPYSL4	0.09	0.03	enet	16	0.05	9.9e-07	4.7	5.2	1.9e-07	-0.02	1.00	0.00	TRUE
2	GTEx	Adipose Subcutaneous	STK32C	0.19	0.10	lasso	7	0.14	3.0e-11	4.8	-5.4	7.5e-08	-0.16	1.00	0.00	TRUE
3	GTEx	Artery Aorta	STK32C	0.22	0.16	lasso	5	0.20	3.3e-11	4.8	-5.5	4.1e-08	-0.13	1.00	0.00	FALSE
4	GTEx	Artery Tibial	INPP5A	0.15	0.06	lasso	7	0.05	1.0e-04	-6.9	-6.3	2.8e-10	-0.11	0.52	0.02	TRUE
5	GTEx	Cells Transformed fibroblasts	DPYSL4	0.53	0.39	enet	14	0.58	1.1e-52	4.7	5.3	1.4e-07	0.03	1.00	0.00	FALSE
6	GTEx	Cells Transformed fibroblasts	STK32C	0.12	0.08	enet	17	0.07	4.5e-06	4.6	-5.6	1.8e-08	-0.13	0.96	0.00	FALSE
7	GTEx	Colon Transverse	STK32C	0.14	-0.01	lasso	6	0.00	6.7e-01	4.8	-7.2	4.1e-13	-0.32	0.04	0.81	TRUE
8	GTEx	Esophagus Mucosa	DPYSL4	0.42	0.21	enet	30	0.36	1.2e-24	4.7	5.8	5.7e-09	0.10	1.00	0.00	FALSE
9	GTEx	Esophagus Mucosa	STK32C	0.15	0.05	lasso	5	0.05	4.6e-04	5.6	-5.2	1.8e-07	-0.14	0.82	0.07	FALSE
10	GTEx	Lung	DPYSL4	0.42	0.23	enet	14	0.41	6.9e-34	4.6	5.2	2.4e-07	0.09	1.00	0.00	FALSE
11	GTEx	Nerve Tibial	STK32C	0.38	0.14	lasso	10	0.26	7.6e-19	4.5	-5.4	7.8e-08	-0.17	1.00	0.00	FALSE
12	GTEx	Pituitary	DPYSL4	0.24	0.11	lasso	4	0.26	3.0e-07	2.3	5.4	7.8e-08	0.14	0.10	0.05	TRUE
13	GTEx	Prostate	DPYSL4	0.41	0.08	lasso	7	0.13	3.4e-04	5.4	5.4	5.7e-08	0.06	0.14	0.14	FALSE
14	GTEx	Prostate	STK32C	0.43	0.11	lasso	9	0.09	2.5e-03	5.6	-5.8	8.5e-09	-0.14	0.10	0.05	FALSE
15	GTEx	Skin Sun Exposed Lower leg	STK32C	0.10	0.02	lasso	5	0.02	4.0e-03	5.9	-6.3	3.3e-10	-0.17	0.44	0.02	FALSE
16	GTEx	Spleen	STK32C	0.37	0.12	lasso	10	0.18	1.7e-05	4.9	-5.9	2.9e-09	-0.18	0.35	0.05	FALSE
17	GTEx	Thyroid	STK32C	0.17	0.07	lasso	8	0.06	2.7e-05	4.8	-6.4	1.5e-10	-0.14	0.89	0.01	FALSE
18	GTEx	Whole Blood	DPYSL4	0.35	0.08	enet	34	0.19	3.9e-17	2.9	5.5	3.9e-08	0.08	1.00	0.00	FALSE
19	ROSMAP	Brain Pre-frontal Cortex	DPYSL4	0.18	0.17	enet	13	0.18	6.4e-23	4.8	5.5	5.2e-08	0.04	1.00	0.00	FALSE
20	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	DPYSL4	0.28	0.22	enet	19	0.25	3.0e-21	-4.4	6.3	2.6e-10	0.02	0.21	0.75	TRUE
21	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	STK32C	0.06	0.06	lasso	1	0.04	2.3e-04	5.6	-5.6	2.6e-08	-0.13	0.08	0.83	FALSE
22	The Cancer Genome Atlas	Breast Invasive Carcinoma	DPYSL4	0.19	0.30	enet	19	0.37	3.1e-79	4.6	5.5	2.9e-08	0.07	0.11	0.88	FALSE
23	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	DPYSL4	0.31	0.19	lasso	10	0.18	3.4e-09	4.6	5.6	2.2e-08	0.02	0.08	0.91	FALSE
24	The Cancer Genome Atlas	Colon Adenocarcinoma	DPYSL4	0.48	0.27	enet	20	0.39	4.5e-24	4.6	5.9	3.2e-09	0.06	0.07	0.92	FALSE
25	The Cancer Genome Atlas	Esophageal Carcinoma	DPYSL4	0.21	0.07	blup	60	0.09	8.2e-04	-4.0	5.9	3.5e-09	0.11	0.03	0.86	FALSE
26	The Cancer Genome Atlas	Glioblastoma Multiforme	STK32C	0.13	-0.01	blup	107	0.08	1.6e-03	3.6	-6.4	1.4e-10	-0.16	0.03	0.39	FALSE
27	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	DPYSL4	0.16	0.24	blup	60	0.27	7.6e-31	-4.0	5.8	7.8e-09	0.05	0.21	0.75	FALSE
28	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	DPYSL4	0.16	0.21	enet	16	0.24	7.1e-27	4.6	5.7	9.3e-09	0.08	0.07	0.91	FALSE
29	The Cancer Genome Atlas	Lung Adenocarcinoma	DPYSL4	0.17	0.16	enet	18	0.23	1.5e-26	4.8	5.5	2.8e-08	0.07	0.06	0.92	FALSE
30	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	DPYSL4	0.11	0.07	blup	60	0.13	1.0e-14	4.6	5.7	1.5e-08	0.06	0.02	0.97	FALSE
31	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	DPYSL4	0.24	0.21	lasso	7	0.28	2.5e-19	4.6	5.5	3.9e-08	0.08	0.01	0.99	FALSE
32	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	LRRC27	0.11	0.02	enet	17	0.04	1.4e-03	5.7	-5.4	7.8e-08	-0.16	0.03	0.47	TRUE
33	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	DPYSL4	0.29	0.17	blup	60	0.35	2.2e-15	4.7	6.2	4.9e-10	0.06	0.02	0.97	FALSE
34	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	STK32C	0.10	0.01	enet	9	0.08	3.4e-04	5.6	-5.7	1.5e-08	-0.19	0.04	0.58	TRUE
35	The Cancer Genome Atlas	Prostate Adenocarcinoma	DPYSL4	0.34	0.37	enet	15	0.46	2.2e-53	-4.3	5.5	3.5e-08	0.06	0.15	0.82	FALSE
36	The Cancer Genome Atlas	Prostate Adenocarcinoma	PWWP2B	0.05	0.01	blup	47	0.01	5.2e-02	-2.3	-7.9	3.8e-15	-0.04	0.02	0.12	TRUE
37	The Cancer Genome Atlas	Rectum Adenocarcinoma	DPYSL4	0.34	0.03	enet	16	0.21	1.2e-05	4.6	7.0	3.4e-12	0.07	0.02	0.55	TRUE
38	The Cancer Genome Atlas	Soft Tissue Sarcoma	DPYSL4	0.14	0.12	lasso	7	0.13	2.5e-08	5.2	5.4	7.0e-08	0.07	0.01	0.99	FALSE
39	The Cancer Genome Atlas	Skin Cutaneous Melanoma	DPYSL4	0.27	0.07	blup	64	0.07	7.1e-03	4.6	5.9	3.8e-09	0.02	0.02	0.52	FALSE
40	The Cancer Genome Atlas	Stomach Adenocarcinoma	DPYSL4	0.23	0.06	lasso	11	0.24	3.7e-17	2.9	5.2	2.3e-07	0.09	0.05	0.94	FALSE
41	The Cancer Genome Atlas	Testicular Germ Cell Tumors	DPYSL4	0.17	0.12	blup	64	0.11	1.3e-04	-4.0	5.6	2.2e-08	0.04	0.08	0.78	FALSE
42	The Cancer Genome Atlas	Thyroid Carcinoma	DPYSL4	0.30	0.24	enet	15	0.38	1.7e-38	2.9	5.2	2.2e-07	0.10	0.19	0.78	FALSE