Best TWAS P=7.88e-08 · Best GWAS P=3.59e-06 conditioned to 0.00252
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | ROSMAP | Brain Pre-frontal Cortex | SLC17A6 | 0.22 | 0.02 | blup | 386 | 0.14 | 3.7e-17 | -2.9 | -5.4 | 7.9e-08 | 0.33 | 0.31 | 0.05 | TRUE |
| 2 | The Cancer Genome Atlas | Liver Hepatocellular Carcinoma | ANO5 | 0.07 | 0.05 | blup | 48 | 0.08 | 1.3e-04 | -4.3 | -5.2 | 1.7e-07 | 0.91 | 0.02 | 0.84 | FALSE |
| 3 | The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | ANO5 | 0.04 | 0.05 | blup | 47 | 0.05 | 4.6e-06 | -4.6 | -5.1 | 3.0e-07 | 0.95 | 0.02 | 0.92 | FALSE |