[Hub]/) : Traits : Heel T-Score : ← →

chr12:11,585,380-13,990,434

Best TWAS P=6.1e-19 · Best GWAS P=2.75e-28 conditioned to 0.926

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	HTR7P1	0.39	0.24	enet	44	0.35	4.2e-44	2.6	-5.3	1.4e-07	-0.24	1.00	0.00	TRUE
2	CommonMind	Brain Pre-frontal Cortex	KIAA1467	0.08	0.09	lasso	2	0.08	2.6e-10	6.3	-6.4	2.0e-10	-0.09	1.00	0.00	FALSE
3	GTEx	Breast Mammary Tissue (Female)	KIAA1467	0.48	-0.01	lasso	23	0.00	3.6e-01	1.2	6.4	1.2e-10	0.12	0.07	0.05	FALSE
4	GTEx	Cells Transformed fibroblasts	LRP6	0.27	0.15	enet	16	0.20	5.5e-15	9.6	6.7	2.2e-11	0.10	0.08	0.92	TRUE
5	GTEx	Cells Transformed fibroblasts	HTR7P1	0.45	0.33	enet	29	0.40	2.2e-31	2.7	-5.9	3.5e-09	-0.25	1.00	0.00	FALSE
6	GTEx	Colon Sigmoid	GPRC5A	0.27	0.00	enet	2	0.00	2.1e-01	8.9	8.9	6.1e-19	0.14	0.75	0.01	TRUE
7	GTEx	Esophagus Muscularis	HEBP1	0.26	0.16	enet	32	0.20	1.7e-12	2.9	6.3	3.3e-10	0.29	1.00	0.00	FALSE
8	GTEx	Uterus	CREBL2	0.61	0.01	lasso	14	0.00	3.3e-01	2.6	5.2	2.3e-07	0.46	0.04	0.28	TRUE
9	METSIM	Adipose	LRP6	0.13	0.05	blup	626	0.05	2.8e-08	9.7	6.4	1.2e-10	0.01	0.09	0.91	FALSE
10	ROSMAP	Brain Pre-frontal Cortex	KIAA1467	0.17	0.05	enet	9	0.06	5.4e-08	6.3	-6.8	1.0e-11	-0.10	1.00	0.00	TRUE
11	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	HTR7P1	0.10	0.03	blup	62	0.05	3.2e-05	2.7	-6.1	1.3e-09	-0.66	0.02	0.96	FALSE
12	The Cancer Genome Atlas	Breast Invasive Carcinoma	KIAA1467	0.02	0.01	blup	51	0.01	2.3e-02	-3.5	5.2	1.9e-07	0.05	0.36	0.02	FALSE
13	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	HTR7P1	0.30	0.04	blup	65	0.09	8.1e-06	1.6	-6.9	6.3e-12	-0.56	0.08	0.49	TRUE
14	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	LRP6	0.05	0.00	enet	16	0.01	3.0e-02	4.0	6.2	4.3e-10	0.04	0.02	0.36	FALSE
15	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	HEBP1	0.07	0.01	blup	68	0.03	4.9e-03	1.7	5.4	6.5e-08	0.24	0.02	0.04	FALSE