[Hub]/) : Traits : Heel T-Score : ← →

chr12:14,220,891-16,190,627

Best TWAS P=7.55e-15 · Best GWAS P=2.67e-16 conditioned to 0.00179

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	ARHGDIB	0.10	0.01	enet	27	0.01	3.6e-02	-8.2	5.5	4.5e-08	-0.68	0.02	0.95	FALSE
2	GTEx	Artery Aorta	ARHGDIB	0.10	0.06	enet	10	0.08	5.4e-05	-6.5	6.4	1.3e-10	-0.83	0.33	0.56	FALSE
3	GTEx	Artery Aorta	C12orf60	0.16	0.10	lasso	6	0.13	1.4e-07	3.6	6.3	2.3e-10	-0.65	0.04	0.95	FALSE
4	GTEx	Artery Tibial	ARHGDIB	0.07	0.02	lasso	7	0.02	6.8e-03	-8.1	7.2	5.7e-13	-0.85	0.04	0.93	FALSE
5	GTEx	Brain Nucleus accumbens basal ganglia	RP11-174G6.5	0.23	0.13	lasso	4	0.11	8.9e-04	-4.5	6.3	2.4e-10	-0.77	0.03	0.87	FALSE
6	GTEx	Nerve Tibial	MGP	0.20	0.09	enet	35	0.10	9.7e-08	-8.1	5.7	1.4e-08	-0.74	0.03	0.97	FALSE
7	GTEx	Nerve Tibial	RERG	0.10	0.01	enet	18	0.01	7.3e-02	-1.6	5.4	5.7e-08	-0.47	0.04	0.66	FALSE
8	GTEx	Thyroid	MGP	0.11	0.04	enet	12	0.06	2.6e-05	-7.5	7.0	1.9e-12	-0.85	0.39	0.59	FALSE
9	GTEx	Thyroid	ARHGDIB	0.12	0.03	enet	20	0.02	7.4e-03	-7.8	7.8	7.6e-15	-0.83	0.06	0.89	TRUE
10	GTEx	Thyroid	C12orf60	0.16	0.10	enet	9	0.12	8.1e-10	3.3	5.8	5.1e-09	-0.62	0.78	0.22	FALSE
11	METSIM	Adipose	ERP27	0.07	0.04	blup	379	0.06	1.7e-09	-6.5	5.6	2.4e-08	-0.70	0.67	0.33	FALSE
12	METSIM	Adipose	MGP	0.04	0.04	bslmm	359	0.04	6.2e-07	-7.4	6.8	1.3e-11	-0.91	0.03	0.97	FALSE
13	NTR	Blood	ARHGDIB	0.01	0.00	blup	377	0.00	5.6e-02	-6.2	5.9	3.4e-09	-0.80	0.09	0.66	FALSE
14	YFS	Blood	ERP27	0.30	0.41	enet	31	0.42	3.1e-152	-5.8	6.3	3.5e-10	-0.83	1.00	0.00	FALSE
15	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	ERP27	0.07	0.03	enet	17	0.04	1.6e-04	-5.9	5.5	4.7e-08	-0.66	0.20	0.49	FALSE
16	The Cancer Genome Atlas	Breast Invasive Carcinoma	ERP27	0.04	0.09	lasso	5	0.09	2.8e-17	-6.2	6.6	4.0e-11	-0.84	0.98	0.02	FALSE
17	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	ERP27	0.09	0.14	lasso	2	0.12	1.7e-06	-6.2	6.3	3.2e-10	-0.81	0.30	0.68	FALSE
18	The Cancer Genome Atlas	Esophageal Carcinoma	ERP27	0.10	0.12	blup	75	0.08	1.5e-03	-5.8	6.6	5.5e-11	-0.85	0.04	0.78	FALSE
19	The Cancer Genome Atlas	Glioblastoma Multiforme	ERP27	0.18	0.07	blup	76	0.11	2.7e-04	-6.5	6.9	5.9e-12	-0.79	0.09	0.62	FALSE
20	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	ERP27	0.10	0.18	lasso	6	0.18	1.2e-19	-6.4	6.5	7.0e-11	-0.86	0.96	0.04	FALSE
21	The Cancer Genome Atlas	Brain Lower Grade Glioma	ERP27	0.07	0.09	blup	73	0.09	4.8e-10	-5.8	6.0	1.5e-09	-0.85	0.79	0.21	FALSE
22	The Cancer Genome Atlas	Lung Adenocarcinoma	ERP27	0.15	0.28	lasso	6	0.28	8.3e-33	-6.2	6.4	2.0e-10	-0.81	1.00	0.00	FALSE
23	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	ERP27	0.17	0.24	enet	13	0.25	6.7e-28	-6.1	6.3	3.1e-10	-0.84	1.00	0.00	FALSE
24	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	C12orf60	0.10	0.01	blup	56	0.07	1.6e-05	3.3	5.2	1.7e-07	-0.63	0.04	0.63	FALSE
25	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	ERP27	0.04	0.05	enet	12	0.04	1.0e-03	-5.9	6.0	1.7e-09	-0.82	0.19	0.45	FALSE
26	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	ERP27	0.14	0.12	lasso	5	0.11	2.9e-05	-6.2	6.2	6.2e-10	-0.80	0.22	0.65	FALSE
27	The Cancer Genome Atlas	Prostate Adenocarcinoma	ERP27	0.13	0.14	lasso	5	0.13	8.3e-14	-5.8	6.0	2.0e-09	-0.81	1.00	0.00	FALSE
28	The Cancer Genome Atlas	Skin Cutaneous Melanoma	ERP27	0.13	0.02	blup	74	0.06	1.4e-02	-6.4	6.8	7.2e-12	-0.82	0.03	0.65	FALSE
29	The Cancer Genome Atlas	Stomach Adenocarcinoma	ERP27	0.07	0.03	blup	76	0.07	1.5e-05	-2.0	5.7	1.6e-08	-0.70	0.07	0.91	FALSE
30	The Cancer Genome Atlas	Testicular Germ Cell Tumors	ERP27	0.10	0.05	lasso	1	0.08	8.9e-04	-6.2	6.2	4.3e-10	-0.81	0.20	0.57	FALSE
31	The Cancer Genome Atlas	Thyroid Carcinoma	ERP27	0.37	0.54	enet	18	0.55	2.3e-63	-6.2	6.6	5.6e-11	-0.83	1.00	0.00	FALSE