Best TWAS P=4.49e-11 · Best GWAS P=3.73e-13 conditioned to 8.86e-06
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | ZNF396 | 0.06 | 0.05 | lasso | 4 | 0.04 | 8.3e-06 | 5.4 | -5.2 | 1.7e-07 | -0.01 | 0.93 | 0.01 | TRUE |
| 2 | METSIM | Adipose | GALNT1 | 0.15 | 0.04 | lasso | 19 | 0.05 | 8.4e-08 | -2.7 | -5.9 | 4.4e-09 | -0.32 | 0.81 | 0.05 | TRUE |
| 3 | The Cancer Genome Atlas | Thyroid Carcinoma | INO80C | 0.07 | 0.01 | blup | 56 | 0.02 | 4.2e-03 | 4.9 | -6.6 | 4.5e-11 | -0.32 | 0.00 | 0.96 | TRUE |