[Hub]/) : Traits : Heel T-Score : ← →

chr18:59,012,796-61,685,225

Best TWAS P=2.44e-17 · Best GWAS P=4.17e-29 conditioned to NaN

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Visceral Omentum	PIGN	0.36	0.12	enet	28	0.26	1.1e-13	2.2	-5.4	7.7e-08	0.19	0.99	0.00	TRUE
2	GTEx	Artery Aorta	PIGN	0.22	0.11	lasso	11	0.15	9.5e-09	-5.3	-5.6	1.8e-08	0.20	0.91	0.02	FALSE
3	GTEx	Artery Coronary	PIGN	0.23	0.02	lasso	11	0.03	3.7e-02	-5.6	-6.5	6.9e-11	0.25	0.15	0.16	FALSE
4	GTEx	Artery Tibial	PIGN	0.19	0.09	lasso	11	0.16	2.4e-12	4.8	-5.3	1.3e-07	0.21	1.00	0.00	FALSE
5	GTEx	Brain Cerebellum	PIGN	0.16	0.06	enet	40	0.06	1.0e-02	-5.6	-5.2	2.6e-07	0.10	0.20	0.10	FALSE
6	GTEx	Breast Mammary Tissue	PIGN	0.18	0.06	lasso	7	0.10	8.7e-06	-5.4	-5.6	1.8e-08	0.18	0.70	0.05	FALSE
7	GTEx	Cells EBV-transformed lymphocytes	PIGN	0.34	0.36	lasso	9	0.35	2.4e-12	-5.4	-6.3	2.4e-10	0.22	0.98	0.02	TRUE
8	GTEx	Cells Transformed fibroblasts	PIGN	0.49	0.43	enet	43	0.52	1.0e-44	2.9	-5.8	5.9e-09	0.24	1.00	0.00	FALSE
9	GTEx	Esophagus Mucosa	PIGN	0.32	0.26	enet	41	0.33	8.6e-23	-5.3	-6.4	1.9e-10	0.23	1.00	0.00	FALSE
10	GTEx	Esophagus Muscularis	PIGN	0.17	0.16	lasso	4	0.17	1.6e-10	-5.7	-6.2	4.5e-10	0.21	1.00	0.00	TRUE
11	GTEx	Lung	PIGN	0.12	0.03	lasso	5	0.09	1.5e-07	2.8	-5.7	9.6e-09	0.23	0.91	0.01	FALSE
12	GTEx	Prostate	PIGN	0.36	0.11	enet	11	0.14	2.6e-04	5.5	-5.5	2.8e-08	0.19	0.24	0.15	FALSE
13	GTEx	Skin Not Sun Exposed Suprapubic	PIGN	0.21	0.05	enet	26	0.16	4.5e-09	-5.5	-5.4	6.8e-08	0.22	0.98	0.00	TRUE
14	GTEx	Skin Sun Exposed Lower leg	TNFRSF11A	0.18	0.08	enet	14	0.11	1.6e-09	-6.0	5.3	1.0e-07	-0.25	0.98	0.00	FALSE
15	GTEx	Skin Sun Exposed Lower leg	PIGN	0.37	0.26	enet	46	0.32	2.3e-27	-5.3	-6.8	8.7e-12	0.26	1.00	0.00	FALSE
16	GTEx	Spleen	PIGN	0.23	0.07	enet	22	0.10	1.3e-03	2.9	-6.1	1.1e-09	0.35	0.10	0.48	FALSE
17	GTEx	Stomach	PIGN	0.18	0.06	lasso	11	0.06	1.0e-03	4.8	-6.4	1.5e-10	0.27	0.62	0.15	FALSE
18	GTEx	Testis	PIGN	0.24	0.27	lasso	7	0.28	1.3e-12	-5.3	-6.1	9.5e-10	0.19	1.00	0.00	FALSE
19	GTEx	Whole Blood	PIGN	0.13	0.08	enet	19	0.07	1.1e-06	-5.4	-5.4	5.2e-08	0.18	0.99	0.01	FALSE
20	METSIM	Adipose	BCL2	0.07	0.01	lasso	4	0.03	9.7e-06	-6.5	-8.5	2.4e-17	0.07	0.16	0.30	TRUE
21	The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	PIGN	0.17	0.04	blup	105	0.11	4.2e-06	-5.6	-5.8	6.0e-09	0.20	0.25	0.70	FALSE
22	The Cancer Genome Atlas	Esophageal Carcinoma	PIGN	0.15	0.09	blup	107	0.10	5.2e-04	-6.5	-5.7	1.6e-08	0.19	0.01	0.97	FALSE
23	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	PIGN	0.12	0.12	enet	15	0.13	4.7e-14	-5.6	-6.2	7.8e-10	0.22	0.35	0.65	FALSE
24	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	PIGN	0.15	0.20	lasso	7	0.24	4.3e-26	4.8	-6.0	2.5e-09	0.22	0.96	0.04	FALSE
25	The Cancer Genome Atlas	Lung Adenocarcinoma	PIGN	0.09	0.06	blup	106	0.08	2.9e-09	-5.3	-6.4	1.7e-10	0.25	0.10	0.89	FALSE
26	The Cancer Genome Atlas	Lung Adenocarcinoma	TNFRSF11A	0.04	0.00	blup	103	0.02	2.0e-03	6.3	7.4	1.7e-13	-0.24	0.07	0.07	TRUE
27	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	PIGN	0.17	0.04	enet	14	0.11	1.6e-12	-5.6	-5.7	1.0e-08	0.22	0.14	0.86	TRUE
28	The Cancer Genome Atlas	Stomach Adenocarcinoma	PIGN	0.18	0.12	enet	13	0.16	1.5e-11	-5.4	-6.2	6.1e-10	0.23	0.40	0.60	FALSE
29	The Cancer Genome Atlas	Testicular Germ Cell Tumors	PIGN	0.29	0.12	lasso	8	0.17	1.1e-06	4.8	-6.1	8.0e-10	0.21	0.10	0.85	TRUE
30	The Cancer Genome Atlas	Thyroid Carcinoma	TNFRSF11A	0.10	0.10	lasso	5	0.09	7.4e-09	-6.0	6.2	4.4e-10	-0.22	1.00	0.00	FALSE
31	The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	PIGN	0.18	0.04	blup	108	0.11	6.3e-04	-5.4	-6.3	2.4e-10	0.21	0.05	0.60	FALSE