Best TWAS P=3.57e-24 · Best GWAS P=5.3e-18 conditioned to 0.000146
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Frontal Cortex BA9 | NFATC1 | 0.42 | -0.01 | lasso | 9 | 0.09 | 2.7e-03 | 5.8 | -6.6 | 4.7e-11 | -0.39 | 0.04 | 0.55 | FALSE |
| 2 | GTEx | Muscle Skeletal | NFATC1 | 0.12 | 0.08 | lasso | 4 | 0.07 | 1.1e-07 | 4.1 | 6.7 | 1.6e-11 | 0.14 | 0.94 | 0.00 | FALSE |
| 3 | METSIM | Adipose | NFATC1 | 0.12 | 0.07 | lasso | 5 | 0.07 | 3.5e-11 | 6.5 | 7.2 | 6.2e-13 | 0.41 | 0.95 | 0.05 | FALSE |
| 4 | YFS | Blood | NFATC1 | 0.17 | 0.08 | bslmm | 444 | 0.15 | 3.1e-46 | 8.3 | 10.1 | 3.6e-24 | 0.54 | 0.04 | 0.96 | TRUE |
| 5 | The Cancer Genome Atlas | Lung Adenocarcinoma | NFATC1 | 0.04 | 0.00 | blup | 117 | 0.01 | 1.0e-02 | 3.1 | 5.2 | 2.0e-07 | 0.53 | 0.01 | 0.55 | FALSE |