[Hub]/) : Traits : Heel T-Score : ← →

chr20:56,265,764-58,262,841

Best TWAS P=3.65e-08 · Best GWAS P=6.75e-10 conditioned to 1.31e-07

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	NELFCD	0.43	0.31	enet	36	0.38	3.3e-33	4.8	-5.4	7.2e-08	0.01	0.00	0.98	TRUE
2	GTEx	Adipose Subcutaneous	VAPB	0.45	0.33	enet	19	0.39	5.4e-34	-5.3	-5.1	2.8e-07	0.08	0.14	0.86	FALSE
3	GTEx	Adipose Visceral Omentum	VAPB	0.34	0.30	lasso	5	0.29	2.3e-15	-5.3	-5.4	8.1e-08	0.08	0.08	0.92	FALSE
4	GTEx	Artery Aorta	VAPB	0.39	0.30	lasso	8	0.31	8.8e-18	-5.3	-5.2	1.7e-07	0.08	0.13	0.87	FALSE
5	GTEx	Artery Coronary	VAPB	0.28	0.26	lasso	4	0.24	1.5e-08	-5.3	-5.3	1.4e-07	0.08	0.10	0.89	FALSE
6	GTEx	Artery Tibial	VAPB	0.44	0.37	lasso	6	0.37	1.1e-30	-5.3	-5.2	1.5e-07	0.07	0.15	0.85	FALSE
7	GTEx	Breast Mammary Tissue	VAPB	0.48	0.22	lasso	9	0.28	1.1e-14	-5.3	-5.2	2.6e-07	0.08	0.12	0.88	FALSE
8	GTEx	Cells EBV-transformed lymphocytes	VAPB	0.65	0.37	enet	13	0.47	3.2e-17	-5.3	-5.2	1.7e-07	0.08	0.15	0.85	FALSE
9	GTEx	Cells Transformed fibroblasts	VAPB	0.32	0.29	lasso	4	0.34	1.2e-26	-5.3	-5.2	2.4e-07	0.08	0.13	0.87	FALSE
10	GTEx	Esophagus Gastroesophageal Junction	VAPB	0.29	0.18	enet	13	0.19	2.2e-07	-5.3	-5.5	3.7e-08	0.16	0.11	0.89	TRUE
11	GTEx	Esophagus Muscularis	VAPB	0.38	0.34	enet	17	0.34	4.0e-21	-5.6	-5.4	7.7e-08	0.09	0.06	0.94	FALSE
12	GTEx	Heart Atrial Appendage	VAPB	0.24	0.21	lasso	2	0.17	5.0e-08	-5.3	-5.3	1.1e-07	0.07	0.11	0.89	FALSE
13	GTEx	Heart Left Ventricle	VAPB	0.21	0.06	lasso	2	0.07	1.1e-04	-5.3	-5.2	1.7e-07	0.07	0.16	0.77	FALSE
14	GTEx	Lung	VAPB	0.24	0.16	lasso	8	0.20	4.4e-15	-5.3	-5.2	2.3e-07	0.08	0.20	0.79	FALSE
15	GTEx	Muscle Skeletal	NELFCD	0.30	0.22	enet	17	0.26	3.5e-25	4.8	-5.2	2.0e-07	-0.01	0.00	0.98	FALSE
16	GTEx	Muscle Skeletal	VAPB	0.17	0.15	enet	10	0.17	1.9e-16	-5.3	-5.2	2.1e-07	0.09	0.09	0.91	FALSE
17	GTEx	Nerve Tibial	NELFCD	0.30	0.17	enet	25	0.23	2.8e-16	4.8	-5.2	1.8e-07	0.01	0.01	0.98	FALSE
18	GTEx	Pancreas	VAPB	0.21	0.11	lasso	4	0.06	1.4e-03	-5.3	-5.2	2.3e-07	0.08	0.18	0.76	FALSE
19	GTEx	Skin Not Sun Exposed Suprapubic	VAPB	0.18	0.16	lasso	2	0.14	3.9e-08	-5.3	-5.3	1.3e-07	0.07	0.15	0.85	FALSE
20	GTEx	Stomach	VAPB	0.29	0.22	enet	7	0.20	1.2e-09	-5.3	-5.1	2.7e-07	0.08	0.17	0.83	FALSE
21	GTEx	Testis	VAPB	0.41	0.18	lasso	6	0.21	1.7e-09	-5.3	-5.3	1.0e-07	0.05	0.16	0.84	FALSE
22	The Cancer Genome Atlas	Esophageal Carcinoma	TH1L	0.19	0.16	blup	46	0.19	8.9e-07	3.6	-5.2	2.1e-07	-0.03	0.04	0.86	FALSE