TWAS hub - NELFCD

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.4260	0.0490	0.0e+00	0.306	NA	0.385	NA	0.359	1.9e-25	NA	3.3e-33	NA	1.6e-30
2	GTEx	Adipose Visceral Omentum	0.2940	0.0690	3.3e-05	0.196	NA	0.224	NA	0.232	1.9e-10	NA	6.7e-12	NA	2.7e-12
3	GTEx	Artery Aorta	0.4330	0.0630	4.8e-11	0.343	NA	0.332	NA	0.371	1.2e-19	NA	6.0e-19	NA	1.8e-21
4	GTEx	Artery Coronary	0.3630	0.1040	5.9e-04	0.197	NA	0.156	NA	0.218	3.3e-07	NA	6.4e-06	NA	6.5e-08
5	GTEx	Artery Tibial	0.2449	0.0505	3.8e-07	0.162	NA	0.150	NA	0.161	1.1e-12	NA	8.0e-12	NA	1.2e-12
6	GTEx	Breast Mammary Tissue	0.4040	0.0740	2.6e-07	0.205	NA	0.137	NA	0.191	8.6e-11	NA	1.6e-07	NA	4.1e-10
7	GTEx	Breast Mammary Tissue (Male)	0.0476	0.1090	3.7e-01	-0.007	NA	-0.013	NA	-0.012	4.9e-01	NA	8.7e-01	NA	7.7e-01
8	GTEx	Breast Mammary Tissue (Female)	0.3548	0.1040	4.7e-03	0.156	NA	0.082	NA	0.092	2.2e-05	NA	2.0e-03	NA	1.1e-03
9	GTEx	Cells Transformed fibroblasts	0.4690	0.0550	1.6e-15	0.292	NA	0.285	NA	0.351	3.7e-22	NA	1.4e-21	NA	2.8e-27
10	GTEx	Esophagus Gastroesophageal Junction	0.4500	0.0890	4.9e-06	0.139	NA	0.145	NA	0.184	1.0e-05	NA	6.7e-06	NA	3.4e-07
11	GTEx	Esophagus Mucosa	0.3230	0.0580	7.3e-09	0.197	NA	0.273	NA	0.260	3.2e-13	NA	2.1e-18	NA	1.7e-17
12	GTEx	Esophagus Muscularis	0.2340	0.0560	3.4e-05	0.149	NA	0.176	NA	0.171	2.5e-09	NA	6.7e-11	NA	1.3e-10
13	GTEx	Heart Atrial Appendage	0.2350	0.0640	3.4e-04	0.168	NA	0.193	NA	0.168	5.3e-08	NA	4.5e-09	NA	5.3e-08
14	GTEx	Lung	0.2176	0.0460	3.7e-07	0.220	NA	0.172	NA	0.210	9.2e-17	NA	3.8e-13	NA	5.0e-16
15	GTEx	Muscle Skeletal	0.2996	0.0467	2.2e-11	0.215	NA	0.258	NA	0.234	8.7e-21	NA	3.5e-25	NA	9.2e-23
16	GTEx	Nerve Tibial	0.3006	0.0513	2.1e-09	0.173	NA	0.230	NA	0.229	2.4e-12	NA	2.8e-16	NA	3.4e-16
17	GTEx	Pancreas	0.1720	0.0630	6.7e-03	0.033	NA	0.048	NA	0.072	1.5e-02	NA	4.4e-03	NA	5.8e-04
18	GTEx	Skin Not Sun Exposed Suprapubic	0.2170	0.0650	7.8e-04	0.147	NA	0.079	NA	0.107	1.9e-08	NA	4.0e-05	NA	1.9e-06
19	GTEx	Skin Sun Exposed Lower leg	0.2800	0.0480	1.3e-11	0.209	NA	0.213	NA	0.215	3.6e-17	NA	1.8e-17	NA	1.1e-17
20	GTEx	Spleen	0.5140	0.1160	3.5e-04	0.308	NA	0.125	NA	0.176	1.2e-08	NA	4.2e-04	NA	2.8e-05
21	GTEx	Testis	0.5310	0.0690	8.9e-09	0.506	NA	0.478	NA	0.514	1.5e-25	NA	1.1e-23	NA	4.2e-26
22	GTEx	Uterus	0.5780	0.1560	3.4e-03	0.068	NA	0.037	NA	0.060	1.7e-02	NA	6.1e-02	NA	2.4e-02
23	GTEx	Vagina	0.6530	0.1280	9.0e-04	0.121	NA	0.067	NA	0.055	1.1e-03	NA	1.3e-02	NA	2.2e-02
24	METSIM	Adipose	0.2514	0.0373	0.0e+00	0.212	0.200	0.221	0.229	0.225	4.2e-31	3.0e-29	1.6e-32	1.1e-33	4.1e-33
25	ROSMAP	Brain Pre-frontal Cortex	0.2386	0.0420	4.8e-11	0.125	0.115	0.138	0.160	0.146	9.0e-16	1.5e-14	2.5e-17	5.4e-20	2.8e-18

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20	21	22	23	24	25
Blood Platelet Count	31.1	360.7	529.0	-19.0	-19.4	-19.3	-19.3	-20.0	-18.9	-18.5	-19.2	-20.5	-23.0	-19.0	-19.4	-17.6	-19.7	-20.7	-18.2	-19.8	-18.0	-19.4	-18.2	-16.4	-19.6	-9.0	-19.2	-19.9
Hypertension (Self-reported)	8.3	23.2	37.7	5.8	5.1	5.3	5.2	5.1	5.2	5.0	5.0	3.9	5.1	5.9	5.4	4.3	5.1	4.2	6.1	5.1	4.7	5.4	4.8	-1.1	3.6	3.7	4.4	3.0
High blood pressure	7.7	21.5	36.6	5.4	5.1	5.1	5.2	4.8	5.0	4.7	4.7	4.1	5.0	5.9	5.3	3.9	5.0	3.9	6.0	5.1	4.5	5.3	4.6	-0.8	3.4	3.2	4.2	2.7
Medication: Blood pressure	6.3	11.2	17.2	4.1	3.2	3.6	3.0	3.5	3.9	3.6	3.5	2.7	3.3	3.8	3.6	3.3	3.5	3.7	4.2	3.4	3.5	3.7	3.1	0.3	2.6	2.9	3.2	2.5
Systolic Blood Pressure	5.9	29.6	53.3	6.3	5.6	5.8	5.8	6.0	5.6	5.5	5.8	4.3	5.6	6.6	5.7	5.4	5.6	5.1	7.3	5.4	5.5	6.0	5.3	-0.4	4.6	4.8	5.3	3.2
Vascular/heart problems diagnosed by doctor	5.8	15.7	30.1	-4.8	-4.3	-4.4	-4.4	-4.2	-4.2	-3.9	-3.9	-3.3	-4.4	-5.1	-4.5	-3.7	-4.1	-3.3	-5.5	-4.2	-3.7	-4.5	-3.9	0.8	-2.8	-2.8	-3.4	-2.1
Medication for cholesterol, blood pressure or diabetes	5.6	9.3	14.9	-3.9	-2.6	-3.4	-2.6	-3.3	-3.7	-3.5	-3.4	-2.3	-2.8	-3.4	-3.3	-2.3	-3.3	-3.6	-3.5	-3.0	-3.5	-3.4	-2.8	-0.5	-2.6	-2.5	-2.9	-2.5
Diastolic blood pressure, automated reading	5.5	16.9	28.5	4.8	4.5	4.4	4.4	4.3	4.3	4.1	4.2	3.6	4.6	5.1	4.4	3.9	4.3	3.5	5.3	4.4	4.1	4.7	4.1	-0.5	3.1	3.0	3.9	2.5
Cardiovascular Disease	5.3	17.4	29.6	5.2	4.3	4.8	4.6	4.8	4.7	4.4	4.3	3.1	5.1	5.3	4.7	2.9	4.4	3.9	5.4	4.2	4.2	4.6	4.1	-0.5	2.8	2.3	3.8	2.1
Falls in the last year	4.8	6.5	11.5	-2.4	-3.0	-2.6	-2.9	-2.5	-2.3	-2.2	-2.5	-3.4	-2.9	-2.9	-2.6	-2.4	-2.5	-2.2	-2.9	-2.7	-1.9	-2.5	-2.3	-3.3	-1.7	0.5	-2.7	-2.7
Medication: Atenolol	4.7	5.9	8.5	2.7	2.4	2.5	2.8	2.6	2.6	2.6	2.5	2.0	2.5	2.9	2.5	2.8	2.5	2.2	2.9	2.5	2.7	2.8	2.3	0.2	2.1	1.2	2.5	1.4
Blood clot in the leg (DVT)	4.6	5.9	10.1	-2.1	-2.7	-2.2	-2.3	-2.5	-2.5	-2.2	-2.3	-2.7	-2.7	-2.2	-2.5	-3.2	-2.6	-2.3	-2.4	-2.8	-2.3	-2.8	-2.1	-0.3	-2.0	-2.1	-2.5	-3.1
Primary Biliary Cirrhosis	4.1	5.9	9.7	-2.8	-2.4	-2.5	-2.4	-2.6	-3.1	-2.6	-2.6	-2.2	-2.5	-2.3	-2.5	-2.9	-2.6	-2.5	-2.4	-2.4	-2.6	-2.6	0.0	-0.5	-2.2	-1.1	-2.9	-2.7
Medication: Simvastatin	3.9	5.8	9.2	2.9	2.2	2.6	2.3	2.4	3.0	2.6	2.7	1.7	1.9	2.6	2.6	2.0	2.6	2.6	3.0	2.4	3.0	2.7	2.2	-0.6	1.8	2.0	2.3	2.0
High cholesterol (Self-reported)	3.8	6.7	11.5	3.0	3.1	2.8	3.4	2.7	2.8	2.4	2.4	2.5	3.2	3.3	3.1	2.2	2.7	2.0	3.2	2.8	2.4	2.9	2.3	-0.1	1.6	1.7	2.4	1.3
Average weekly beer plus cider intake	3.8	5.5	8.6	-2.5	-2.9	-2.3	-2.7	-2.3	-2.1	-2.0	-2.3	-2.8	-2.3	-2.8	-2.8	-2.2	-2.5	-2.2	-2.9	-2.9	-1.4	-2.6	-2.3	-0.5	-2.0	-1.3	-2.4	-2.2
Pack years adult smoking proportion	3.7	5.7	9.3	-2.3	-1.9	-2.7	-2.0	-2.5	-2.5	-3.0	-2.9	-1.6	-1.8	-2.4	-2.5	-1.2	-2.6	-2.6	-2.1	-2.3	-2.8	-2.6	-2.5	-0.3	-2.6	-2.2	-3.0	-2.9
Osteoarthritis (self-reported)	3.6	4.7	7.4	-1.8	-2.6	-2.4	-2.2	-2.4	-2.3	-2.1	-2.1	-2.5	-2.1	-2.7	-2.5	-1.1	-2.5	-1.4	-2.5	-2.7	-2.0	-2.6	-2.3	0.2	-1.2	0.4	-2.4	-2.3
Pack years of smoking	3.6	5.4	8.5	-2.2	-2.0	-2.7	-2.0	-2.5	-2.4	-2.8	-2.7	-1.7	-1.8	-2.5	-2.5	-1.2	-2.6	-2.4	-2.3	-2.3	-2.6	-2.6	-2.3	-0.1	-2.5	-1.9	-2.9	-2.5
Lupus	3.3	4.9	7.3	2.5	1.8	2.4	1.8	2.2	2.5	2.6	2.3	2.0	2.3	2.1	1.9	2.3	2.4	2.5	1.9	2.2	2.4	2.2	2.6	1.5	1.8	1.7	2.4	2.7
Systolic blood pressure, automated reading	3.3	9.7	19.5	3.7	3.8	3.1	3.9	2.9	2.9	2.6	2.9	2.9	3.5	4.0	3.3	3.1	3.1	2.6	4.4	3.3	2.8	3.4	2.6	-0.6	2.1	3.5	2.5	1.4
Medication: Cholesterol lowering	3.3	5.1	7.8	2.6	2.2	2.5	2.2	2.5	2.8	2.4	2.3	2.1	2.4	2.7	2.5	1.7	2.4	2.5	2.7	2.4	2.5	2.6	1.9	0.5	1.6	1.9	1.8	1.7
Medication: Lisinopril	3.3	4.3	7.6	2.8	2.0	2.3	1.8	1.9	2.3	2.2	2.1	1.8	1.6	2.3	2.4	1.5	2.2	1.8	2.4	2.1	2.0	2.4	2.2	0.5	2.5	1.3	2.1	2.1
Frequency of unenthusiasm / disinterest in last 2 weeks	3.2	4.3	7.3	-2.4	-2.3	-2.1	-2.5	-1.5	-1.8	-2.0	-2.0	-2.3	-2.1	-2.2	-1.9	-1.6	-2.0	-2.7	-1.8	-2.0	-1.6	-2.1	-2.2	-2.2	-2.1	-0.6	-2.3	-2.3
Deep venous thrombosis (DVT) (self-reported)	3.2	4.1	7.9	-1.7	-2.1	-1.7	-1.7	-2.2	-2.1	-1.8	-1.9	-2.3	-2.3	-1.7	-2.0	-2.8	-2.2	-2.0	-1.9	-2.3	-1.9	-2.3	-1.7	-0.5	-1.7	-2.0	-2.1	-2.7
Impedance of leg (right)	3.0	14.6	21.4	4.6	3.7	4.1	3.5	4.0	4.0	3.8	4.2	3.7	3.6	4.0	4.1	2.4	4.0	4.4	4.2	3.8	4.0	4.1	3.7	1.9	4.5	1.4	3.4	4.5
Hayfever/allergic rhinitis (self-reported)	3.0	4.0	8.6	-2.1	-2.0	-2.2	-2.2	-1.9	-2.0	-2.2	-2.2	-1.6	-2.1	-2.1	-2.2	-1.8	-2.1	-1.8	-1.8	-1.9	-2.2	-2.1	-1.9	-0.8	-1.4	-0.8	-2.4	-2.9
Depression (Nagel 2018)	2.9	4.4	7.9	-2.3	-2.7	-2.1	-2.7	-1.8	-1.7	-1.6	-1.7	-2.8	-2.2	-2.5	-2.1	-1.6	-2.1	-2.6	-2.5	-2.5	-1.4	-2.2	-1.8	-1.7	-1.8	-0.4	-2.0	-2.2
Current tobacco smoking	2.9	4.8	8.2	-2.6	-1.9	-2.2	-2.3	-2.3	-2.0	-2.3	-2.1	-1.8	-2.3	-2.0	-2.4	-2.9	-2.1	-2.3	-2.3	-2.0	-2.2	-2.3	-2.5	-1.5	-1.8	-1.2	-2.6	-2.2
Impedance of leg (left)	2.9	14.1	20.5	4.5	3.6	4.0	3.4	4.1	4.0	3.7	4.1	3.7	3.5	3.9	4.0	2.7	3.9	4.3	4.2	3.8	4.0	3.9	3.5	1.9	4.3	2.0	3.1	4.3
Mouth/teeth dental problems: Loose teeth	2.9	3.4	4.8	1.5	1.7	1.7	1.3	2.0	2.2	2.0	2.1	2.0	1.8	1.8	1.6	2.2	2.1	2.0	1.5	2.1	1.9	2.0	1.9	1.5	1.6	0.7	2.0	2.0
Illnesses of father: High blood pressure	2.9	3.7	7.1	1.7	1.7	2.1	1.6	2.1	2.1	2.3	2.2	1.5	1.6	2.1	2.0	1.8	2.1	1.4	2.1	2.0	2.1	2.2	2.0	-0.6	1.5	2.7	2.1	1.1
Ovarian Cancer	2.8	3.7	6.1	-2.3	-1.9	-2.1	-1.9	-1.5	-2.1	-2.1	-2.2	-1.6	-2.0	-2.0	-2.0	-0.7	-2.0	-2.4	-1.7	-1.9	-1.8	-2.1	-2.5	-0.4	-1.9	-2.0	-2.0	-2.2
Heel T-Score	2.6	20.9	29.1	-5.4	-4.3	-4.8	-4.3	-5.1	-4.6	-4.8	-5.0	-3.7	-5.0	-4.8	-4.9	-4.7	-4.8	-5.2	-5.2	-4.6	-4.4	-4.8	-4.9	-0.6	-4.9	-1.5	-4.8	-4.0
Reason for reducing amount of alcohol drunk: Health precaution	2.6	3.0	6.2	1.4	1.8	1.9	1.7	1.7	2.2	1.8	1.7	1.7	1.8	1.9	1.9	1.8	1.8	1.8	1.7	1.7	1.8	1.8	1.1	0.8	2.5	0.5	1.7	1.9
Medication: Bendroflumethiazide	2.6	3.9	13.8	2.2	1.7	2.1	1.8	1.9	2.1	2.1	2.1	1.0	1.3	2.2	2.1	1.5	2.0	1.9	2.3	1.9	2.2	2.0	1.9	-1.6	1.4	3.7	1.7	1.1
Blood Red Count	2.5	24.6	36.0	4.7	5.2	4.8	5.0	5.1	4.9	4.7	5.0	6.0	5.7	5.1	5.0	4.3	5.1	4.9	4.8	5.4	4.7	5.2	4.3	5.7	5.0	1.4	5.3	5.1
Length of working week for main job	2.5	2.7	7.1	-1.3	-1.4	-1.7	-1.6	-1.9	-1.7	-1.8	-1.8	-1.3	-1.6	-1.5	-1.6	-2.7	-1.7	-1.6	-1.8	-1.5	-2.1	-1.7	-1.6	-0.7	-1.6	-0.3	-1.7	-1.7
Frequency of depressed mood in last 2 weeks	2.4	3.4	6.2	-2.2	-2.2	-1.9	-2.5	-1.6	-1.6	-1.5	-1.5	-2.2	-1.9	-2.2	-1.8	-1.7	-1.8	-2.3	-2.0	-2.0	-1.1	-1.8	-1.8	-1.4	-1.3	-0.5	-2.0	-1.9
Mouth/teeth dental problems: Mouth ulcers	2.3	3.7	6.5	1.8	2.4	2.1	2.4	1.5	2.0	1.6	2.1	2.5	2.2	2.4	2.4	1.3	2.0	1.3	1.6	2.2	1.4	2.0	1.4	1.3	2.5	-0.3	1.2	2.2
Illnesses of siblings: Diabetes	2.2	2.7	7.4	-1.6	-2.5	-1.5	-2.7	-1.3	-1.3	-0.7	-0.9	-2.5	-1.8	-2.2	-2.0	-2.0	-1.5	-0.6	-2.2	-2.0	-0.9	-1.6	-1.2	-0.9	0.1	-0.7	-1.7	-0.8
Number of self-reported non-cancer illnesses	2.2	3.8	9.7	2.5	1.8	2.1	2.0	2.1	1.9	2.0	1.9	1.1	2.5	2.2	2.0	1.6	1.9	1.8	2.4	1.8	1.8	2.0	1.9	-1.0	1.4	3.1	1.2	0.4
Loud music exposure frequency	2.1	2.3	4.4	-1.7	-1.5	-1.5	-1.5	-1.9	-1.4	-1.5	-1.5	-1.7	-1.6	-1.6	-1.6	-0.6	-1.6	-1.4	-1.3	-1.7	-1.3	-1.6	-1.7	-1.0	-2.1	0.0	-1.3	-1.7
Angina (self-reported)	2.1	2.8	6.8	2.6	1.4	1.6	1.4	2.1	1.8	1.6	1.6	0.9	1.7	1.9	1.6	2.5	1.5	1.7	2.4	1.5	1.2	1.6	1.6	-0.8	1.1	-0.2	1.8	1.6
Smoking status: Current	2.1	3.3	6.3	-2.3	-1.6	-1.8	-2.0	-1.9	-1.5	-1.8	-1.7	-1.5	-1.9	-1.7	-1.9	-2.5	-1.7	-2.1	-1.9	-1.6	-1.7	-1.8	-2.1	-1.5	-1.6	-1.2	-2.2	-1.8
Angina	2.0	2.6	7.1	2.7	1.3	1.5	1.3	2.0	1.9	1.6	1.6	0.8	1.6	1.8	1.5	2.4	1.4	1.7	2.3	1.4	1.2	1.5	1.6	-0.6	1.2	0.1	1.8	1.5
Diverticular disease/diverticulitis (self-reported)	2.0	2.4	7.6	1.3	1.7	1.6	1.7	1.5	1.3	1.3	1.2	1.6	2.1	1.6	1.6	1.3	1.5	1.2	1.8	1.5	1.1	1.5	1.4	1.4	1.5	2.8	1.6	0.8
Medication: Blood pressure	1.9	3.6	8.4	2.2	2.0	2.1	2.2	2.1	1.7	1.8	1.8	0.9	1.8	2.5	2.2	1.7	1.9	1.0	2.9	1.9	1.7	2.1	2.1	-2.3	1.3	1.5	1.5	0.1
High blood pressure (mother)	1.8	2.6	4.8	2.1	1.5	1.7	1.8	1.9	1.9	1.5	1.6	0.9	1.6	1.9	1.6	2.2	1.6	1.7	2.1	1.4	1.8	1.7	1.7	-1.1	0.5	0.7	1.2	0.4
Hair/balding pattern: Pattern 3	1.8	2.7	4.3	2.0	1.6	2.0	1.7	1.5	1.8	1.9	1.9	1.6	1.3	1.8	2.0	1.1	1.8	1.4	1.9	1.6	1.6	1.8	1.4	0.6	2.1	0.7	1.5	1.7
Risk taking	1.8	2.6	4.7	-1.8	-1.3	-1.7	-1.2	-2.0	-1.8	-1.9	-1.7	-1.0	-1.4	-1.5	-1.7	-1.8	-1.7	-1.3	-2.2	-1.5	-1.9	-1.8	-1.4	0.1	-1.2	-1.3	-2.0	-1.4
Worry (Nagel 2018)	1.7	3.5	6.5	2.5	1.5	2.1	1.7	1.8	2.2	2.1	2.1	1.1	1.6	1.9	2.1	1.9	1.8	2.4	2.3	1.5	2.2	2.1	1.7	-0.2	1.9	1.0	1.8	1.9
Mother’s age at death	1.7	2.1	4.7	1.7	1.1	1.5	1.3	1.4	1.7	1.5	1.5	1.1	1.2	1.1	1.3	0.7	1.4	1.3	1.1	1.2	1.5	1.2	1.8	0.6	2.2	1.9	1.6	2.1
Prospective memory result	1.6	1.9	3.7	-1.1	-1.2	-1.4	-0.9	-1.5	-1.7	-1.6	-1.5	-1.2	-1.4	-1.2	-1.4	-1.2	-1.6	-1.3	-0.9	-1.4	-1.6	-1.6	-1.3	-0.6	-0.9	-1.9	-1.5	-1.7
Seen a psychiatrist for nerves, anxiety, tension or depression	1.6	2.1	3.7	-1.0	-1.3	-1.4	-1.0	-1.9	-1.7	-1.6	-1.4	-1.8	-1.8	-1.5	-1.3	-0.8	-1.5	-1.6	-1.4	-1.6	-1.5	-1.5	-1.7	-1.9	-1.1	0.9	-1.6	-0.6
Impedance of whole body	1.6	8.1	12.7	3.3	2.6	3.0	2.6	3.4	3.2	2.9	3.2	2.3	2.4	3.0	3.2	1.8	2.9	3.6	3.5	2.7	3.0	2.9	2.8	0.1	3.3	1.6	2.3	3.0
Fluid intelligence score	1.5	3.2	9.0	2.0	1.5	1.5	1.6	1.8	1.7	1.8	1.5	1.1	1.8	1.5	1.6	3.0	1.7	1.4	1.8	1.7	1.4	1.6	2.1	-0.2	1.7	3.0	1.9	1.9
Medication: Ventolin 100micrograms inhaler	1.5	1.9	5.6	1.5	2.2	1.2	1.7	0.9	1.1	0.7	1.2	2.4	1.3	1.8	1.6	1.7	1.3	0.8	2.0	1.9	1.0	1.7	0.8	0.7	0.8	0.5	0.9	0.8
Suffer from ‘nerves’	1.5	2.4	4.3	2.1	1.1	1.8	1.0	1.9	1.9	1.8	1.7	0.9	1.3	1.4	1.6	1.4	1.6	1.8	1.6	1.3	1.8	1.7	1.4	-0.1	2.1	1.4	1.1	1.3
Loneliness, isolation	1.5	2.1	5.5	-1.1	-0.5	-1.3	-0.8	-1.5	-1.5	-1.8	-1.6	-0.7	-1.0	-0.8	-0.9	-1.7	-1.3	-2.3	-1.0	-0.8	-1.9	-1.2	-1.3	-2.2	-2.2	1.0	-2.3	-1.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.5	3.3	5.9	-1.8	-2.1	-1.7	-2.1	-1.8	-1.8	-1.7	-2.0	-2.1	-1.8	-2.1	-1.9	-2.4	-1.9	-1.7	-1.6	-2.1	-1.8	-1.9	-1.9	-0.4	-1.0	-0.9	-1.9	-1.1
Irritable Bowel Disease (IBD)	1.4	3.4	10.0	1.7	2.0	1.6	1.8	1.3	1.6	1.7	1.9	2.6	2.0	1.8	1.8	1.2	1.8	3.1	1.7	1.8	2.0	1.9	1.0	3.2	1.6	0.5	1.0	1.5
Medication: Levothyroxine sodium	1.4	2.4	4.8	2.2	1.4	1.4	1.6	1.5	1.2	1.6	1.6	1.1	1.7	1.5	1.5	2.1	1.5	1.4	1.7	1.5	1.6	1.7	1.5	-0.0	2.1	0.0	2.0	1.5
Nervous feelings	1.4	2.6	4.2	2.0	1.5	1.8	1.6	1.5	1.7	1.6	2.0	1.3	1.2	1.8	1.9	1.5	1.7	1.7	1.7	1.7	1.8	1.9	0.8	-0.1	2.0	-0.3	1.7	2.0
Heart attack	1.4	1.8	5.3	-1.0	-1.7	-1.3	-1.8	-0.6	-0.8	-1.1	-1.4	-2.0	-1.1	-1.2	-1.4	-0.4	-1.4	-1.2	-0.1	-1.5	-1.2	-1.4	-1.0	-1.6	-0.9	-0.5	-1.6	-2.3
Ever had stillbirth, spontaneous miscarriage or termination	1.4	1.5	3.8	0.8	1.7	1.4	1.4	1.7	1.1	0.9	1.1	1.6	2.0	1.7	1.5	0.9	1.3	0.6	1.3	1.6	0.8	1.3	0.9	0.0	0.2	0.8	0.6	0.7
Waist Hip Ratio (WHR)	1.3	6.1	9.1	2.4	3.0	2.7	3.0	2.2	2.1	2.3	2.4	2.8	2.9	2.9	3.0	1.7	2.6	1.8	2.7	2.7	2.4	2.7	2.8	0.9	2.3	1.5	2.4	2.2
Townsend deprivation index at recruitment	1.3	1.8	2.8	-1.4	-1.7	-1.3	-1.4	-0.9	-1.3	-1.1	-1.1	-1.6	-1.7	-1.4	-1.5	-1.7	-1.4	-0.7	-1.5	-1.6	-0.9	-1.6	-1.2	-0.3	-1.3	-1.3	-1.3	-1.5
Tinnitus: Yes, but not now, but have in the past	1.3	1.4	3.3	-1.4	-0.9	-1.2	-0.9	-0.7	-1.8	-1.5	-1.4	-1.0	-0.6	-0.9	-1.1	-0.1	-1.4	-1.1	-0.9	-1.2	-1.2	-1.5	-1.5	0.0	-0.9	-0.1	-1.7	-1.7
High blood pressure (siblings)	1.3	1.8	5.8	2.4	1.2	1.4	1.3	1.1	1.3	1.4	1.5	0.7	1.1	1.6	1.4	0.8	1.3	1.4	1.9	1.2	1.3	1.6	1.6	-0.8	1.4	0.4	1.4	1.0
Smoking status: Previous	1.3	2.0	5.1	1.0	1.2	1.6	1.4	1.5	1.5	1.5	1.2	1.4	1.1	1.4	1.5	0.8	1.5	1.6	1.4	1.4	1.3	1.5	1.8	1.6	0.9	2.3	1.0	1.5
Heart disease (siblings)	1.3	1.6	2.9	-1.0	-1.3	-1.2	-1.3	-1.4	-1.5	-1.2	-1.2	-1.5	-1.4	-1.1	-1.2	-0.9	-1.2	-1.3	-1.0	-1.3	-1.3	-1.2	-1.1	-1.2	-1.2	-1.7	-1.6	-0.7
Crohns Disease (2017)	1.2	2.7	7.9	1.7	1.6	1.5	1.6	1.4	1.7	1.9	2.1	1.6	1.9	1.5	1.7	1.2	1.7	2.8	1.6	1.6	1.9	1.8	1.0	1.5	1.1	-0.2	1.5	1.5
Ulcerative Colitis (UC)	1.2	2.2	14.9	0.8	1.6	1.0	1.3	0.8	0.9	0.9	1.1	2.6	1.3	1.3	1.2	1.0	1.2	2.3	1.1	1.4	1.4	1.3	0.8	3.9	1.4	1.1	0.6	1.1
Bipolar Disorder (2011)	1.2	1.1	2.9	0.0	1.4	1.2	1.4	0.8	1.3	0.0	0.0	1.6	1.3	1.4	0.0	0.1	1.3	1.0	1.0	1.2	0.0	1.3	0.0	1.7	0.0	1.1	1.4	1.4
Back pain experienced in last month	1.2	1.8	11.1	-1.1	-1.3	-0.8	-1.2	-0.9	-0.9	-0.8	-1.0	-2.0	-1.5	-1.0	-0.9	-1.2	-1.1	-1.6	-0.7	-1.2	-0.5	-1.2	-0.8	-3.3	-1.4	-0.2	-1.7	-1.6
Fractured/broken bones in last 5 years	1.2	1.5	2.6	-1.4	-1.3	-1.4	-1.5	-1.1	-1.2	-1.2	-1.4	-1.2	-1.0	-1.3	-1.4	-0.4	-1.3	-1.2	-1.4	-1.2	-1.2	-1.3	-0.9	-0.6	-1.6	0.2	-1.3	-1.4
Heart attack/myocardial infarction (self-reported)	1.2	1.6	4.8	-0.9	-1.6	-1.3	-1.6	-0.6	-0.8	-1.1	-1.4	-1.9	-1.1	-1.1	-1.3	-0.3	-1.3	-1.1	-0.1	-1.4	-1.2	-1.4	-1.1	-1.7	-1.0	-0.3	-1.5	-2.2
Neuroticism (Nagel 2018)	1.1	2.7	4.4	2.0	1.5	1.9	1.6	1.6	1.8	1.7	1.7	1.1	1.8	1.7	1.9	1.3	1.6	1.6	2.0	1.4	1.6	1.8	1.6	-0.3	1.3	2.1	1.2	1.6
Medication: Ramipril	1.1	1.4	4.7	1.2	1.0	1.3	1.1	1.4	1.2	1.1	1.2	0.6	0.9	1.5	1.4	2.2	1.2	0.5	2.2	1.1	1.0	1.0	1.2	-1.1	0.3	0.9	0.8	0.5
Ever highly irritable/argumentative for 2 days	1.1	1.3	2.6	-1.3	-1.0	-1.1	-1.0	-1.1	-0.9	-1.2	-1.1	-1.3	-0.8	-1.0	-1.0	-0.5	-1.3	-1.3	-1.1	-1.3	-0.8	-1.1	-1.1	-1.2	-1.6	0.1	-1.4	-1.6
Chronic bronchitis/emphysema (mother)	1.1	1.2	2.7	-1.6	-1.1	-1.1	-1.4	-1.0	-1.1	-1.0	-0.8	-0.6	-0.7	-1.3	-1.1	-1.0	-1.0	-1.5	-1.3	-0.9	-1.1	-0.9	-0.8	0.8	-0.8	-1.4	-1.1	-1.6
Leg predicted mass (right)	1.1	5.6	12.7	-3.2	-2.2	-2.1	-2.3	-2.2	-2.3	-2.2	-2.3	-2.1	-1.8	-2.1	-2.4	-2.0	-2.2	-3.1	-2.4	-2.1	-2.5	-2.5	-2.2	-1.4	-2.9	-0.8	-2.8	-3.6
Bipolar Disorder (2018)	1.0	1.5	4.4	1.0	2.1	1.3	1.8	0.8	1.0	0.7	0.9	2.0	1.5	1.8	1.5	0.2	1.3	0.6	1.3	1.7	0.7	1.2	1.2	0.0	0.6	0.8	0.5	1.3
Crohns Disease (2012)	1.0	1.6	3.1	1.0	1.6	1.0	1.8	1.1	1.0	1.0	1.3	1.8	1.6	1.4	1.3	1.2	1.2	1.7	1.1	1.3	0.9	1.3	0.2	1.6	0.9	0.3	1.0	1.1
HbA1C	1.0	1.1	3.2	-1.0	-0.5	-1.1	-0.4	-1.7	-1.1	-1.3	-1.2	-0.5	-1.8	-0.7	-0.8	-0.5	-1.2	-1.6	-1.0	-1.0	-1.2	-1.0	-1.5	0.4	-0.5	0.8	-1.2	-0.5
Breastfed as a baby	1.0	1.2	2.6	0.6	0.9	1.2	0.5	0.9	1.6	1.3	1.4	1.1	0.6	0.9	1.2	-0.2	1.4	0.6	0.9	1.4	1.6	1.5	1.2	-0.3	1.1	1.1	1.6	0.9
Glaucoma (self-reported)	1.0	1.2	2.6	-0.8	-0.7	-1.1	-0.5	-1.4	-1.1	-1.3	-1.0	-1.0	-0.9	-1.0	-1.0	0.3	-1.2	-1.1	-1.3	-1.1	-1.2	-1.1	-0.7	-1.1	-1.6	-1.5	-1.1	-1.1
Worry too long after embarrassment	1.0	1.7	4.7	1.6	1.1	1.2	1.5	1.2	1.2	1.1	1.2	0.8	1.7	1.2	1.3	2.2	1.1	1.3	1.5	1.1	1.2	1.2	0.9	0.0	1.3	1.7	1.1	1.4
Leg fat-free mass (right)	1.0	5.5	12.7	-3.2	-2.2	-2.1	-2.3	-2.1	-2.3	-2.1	-2.3	-2.1	-1.7	-2.1	-2.4	-2.0	-2.2	-3.1	-2.4	-2.1	-2.5	-2.5	-2.1	-1.4	-2.9	-0.7	-2.7	-3.6
Medication: Omeprazole (e.g. Zanprol)	1.0	1.2	2.5	-1.5	-0.9	-1.2	-1.3	-0.5	-1.4	-1.2	-1.5	-0.9	-0.5	-1.0	-0.9	0.3	-1.1	-1.6	-0.2	-0.9	-1.6	-1.1	-0.7	-0.9	-1.4	-0.4	-1.0	-1.5
Alcohol drinker status: Previous	1.0	1.1	3.4	1.2	1.8	0.8	1.7	0.5	0.5	0.4	0.6	1.6	1.4	1.5	1.2	1.1	0.8	0.6	1.2	1.2	0.4	1.0	0.7	0.8	0.1	0.1	0.8	1.2
Depressed Affect (Nagel 2018)	0.9	1.9	3.4	1.6	1.4	1.7	1.6	1.4	1.3	1.4	1.4	0.9	1.8	1.5	1.7	1.0	1.4	0.8	1.6	1.3	1.2	1.4	1.5	-0.8	1.4	1.3	0.9	1.0
Neuroticism	0.9	2.2	3.3	1.8	1.1	1.8	1.3	1.5	1.8	1.8	1.6	0.4	1.6	1.5	1.7	1.1	1.5	1.1	1.5	1.3	1.7	1.6	1.4	-1.4	1.2	1.8	1.1	1.2
Severe depression (siblings)	0.9	1.0	3.7	1.0	1.5	0.6	1.4	0.7	0.0	0.2	0.7	1.4	1.2	1.1	1.1	1.9	0.8	0.2	1.2	1.2	0.1	0.9	0.4	-0.1	-0.2	1.7	0.6	0.8
Leg fat-free mass (left)	0.9	4.8	10.6	-3.0	-2.0	-1.9	-2.1	-2.1	-2.2	-2.0	-2.1	-1.9	-1.6	-1.9	-2.2	-2.1	-2.0	-2.9	-2.3	-1.9	-2.3	-2.2	-1.9	-1.3	-2.6	-1.0	-2.5	-3.2
Stomach or abdominal pain in last month	0.9	1.1	2.7	-1.2	-1.6	-1.0	-1.6	-0.7	-1.2	-0.5	-1.0	-1.5	-1.3	-1.4	-1.2	-0.3	-1.0	-1.0	-1.2	-1.4	-0.4	-1.1	-0.7	-0.3	-1.0	-0.5	-0.6	-0.9
Leg predicted mass (left)	0.9	4.6	10.4	-3.0	-1.9	-1.9	-2.0	-2.1	-2.1	-1.9	-2.1	-1.9	-1.5	-1.8	-2.1	-2.0	-2.0	-2.8	-2.2	-1.9	-2.3	-2.2	-1.9	-1.3	-2.5	-1.0	-2.5	-3.2
Mouth/teeth dental problems	0.9	1.3	3.2	-0.9	-1.2	-1.4	-0.9	-0.5	-1.7	-1.3	-1.6	-1.5	-0.3	-1.3	-1.3	-0.5	-1.4	-1.0	-0.8	-1.4	-1.5	-1.5	-0.6	-0.2	-1.3	0.0	-0.6	-1.8
Worrier / anxious feelings	0.9	1.6	3.9	1.6	0.8	1.2	0.7	1.5	1.5	1.4	1.3	-0.0	1.1	1.1	1.4	1.6	1.2	1.5	1.4	1.0	1.3	1.3	1.1	-2.0	1.0	0.7	1.3	1.2
Qualifications: A levels/AS levels or equivalent	0.9	2.0	4.5	1.0	1.4	1.4	1.3	1.7	2.1	1.7	1.9	1.0	1.9	1.2	1.4	0.9	1.6	0.9	0.7	1.6	1.7	1.5	1.3	-0.2	1.4	0.4	1.8	1.4
Neck or shoulder pain in last month	0.9	1.2	2.4	-1.3	-1.2	-1.2	-1.4	-0.8	-1.1	-1.3	-1.3	-0.9	-1.0	-1.1	-1.3	-0.9	-1.3	-1.6	-0.7	-1.2	-1.2	-1.1	-0.9	0.0	-0.8	0.3	-1.3	-1.0
Commuting to job workplace: Car/motor vehicle	0.9	1.0	3.0	-0.7	-1.3	-0.8	-1.6	-0.7	-0.6	-0.6	-0.8	-1.7	-0.5	-1.1	-1.0	-0.8	-1.0	-0.9	-1.1	-1.2	-0.6	-1.1	-0.4	-1.7	0.1	0.8	-1.0	-0.7
Medication: Atorvastatin	0.9	1.1	2.4	0.8	1.0	1.2	1.3	1.6	1.1	1.2	1.0	0.8	1.5	1.3	1.1	1.0	1.2	0.5	0.9	1.1	0.9	1.2	0.8	0.2	0.9	0.3	1.4	0.5
Type 2 Diabetes (T2D) (2012)	0.8	0.9	6.4	0.8	1.0	0.8	1.2	0.5	0.9	0.7	1.0	1.0	0.9	0.9	0.8	0.4	0.8	0.5	0.3	0.8	0.7	0.8	0.7	0.8	1.0	2.5	0.7	0.9
Allergy or Eczema	0.8	2.1	4.3	-1.5	-1.6	-1.5	-1.3	-1.4	-1.3	-1.5	-1.4	-1.7	-1.2	-1.5	-1.5	-1.0	-1.6	-1.8	-0.7	-1.6	-1.6	-1.6	-1.5	-0.9	-1.0	-0.9	-2.1	-1.5
Sensitivity / hurt feelings	0.8	1.4	3.0	0.6	1.4	1.5	1.2	1.2	1.5	1.1	1.2	1.4	1.1	1.4	1.4	0.4	1.3	0.5	1.0	1.3	1.1	1.3	1.0	-0.0	0.9	1.7	0.4	1.5
Frequency of tenseness / restlessness in last 2 weeks	0.8	1.2	2.7	-1.4	-1.3	-1.0	-1.3	-0.8	-1.0	-1.0	-0.9	-1.2	-0.9	-1.1	-0.9	-1.3	-1.1	-1.6	-0.8	-1.1	-0.9	-1.0	-1.2	-0.6	-0.8	0.1	-0.9	-1.6
Depression (self-reported)	0.8	1.0	2.1	-1.2	-1.0	-0.9	-0.9	-0.8	-1.3	-1.0	-0.9	-0.6	-0.7	-1.0	-1.1	-1.5	-1.0	-1.1	-1.3	-0.9	-0.9	-1.1	-1.1	0.9	-0.5	-0.4	-1.4	-0.8
Migraine (self-reported)	0.8	1.0	2.1	0.6	1.1	1.1	1.0	0.9	1.5	1.1	1.3	0.9	0.8	1.3	1.0	1.0	1.1	0.8	1.2	1.1	1.4	1.1	0.4	0.1	0.6	0.8	0.9	0.5
Medication: Omeprazole	0.8	1.0	2.0	-1.4	-0.8	-1.0	-1.1	-0.3	-1.1	-1.0	-1.3	-1.0	-0.1	-0.9	-0.8	0.2	-1.0	-1.4	-0.2	-0.9	-1.3	-0.9	-0.7	-1.1	-1.4	-0.3	-0.9	-1.4
Supplements: Vitamin C	0.8	0.9	2.7	-1.0	0.0	-0.9	-0.1	-1.3	-1.3	-1.4	-1.3	0.1	-0.3	-0.3	-0.7	-0.9	-1.0	-1.5	-0.4	-0.5	-1.6	-0.7	-0.5	-0.1	-1.2	-0.1	-1.2	-1.3
Knee pain experienced in last month	0.8	1.2	3.5	-1.1	-1.2	-1.1	-1.4	-1.2	-1.4	-1.1	-0.9	-0.7	-1.0	-1.2	-1.3	-0.8	-1.2	-0.6	-0.8	-1.2	-0.7	-1.2	-0.9	0.9	-0.2	-0.9	-1.9	-1.5
Eye problems/disorders: Glaucoma	0.8	0.9	4.9	-0.4	-0.5	-0.8	-0.2	-1.0	-0.6	-0.8	-0.5	-1.1	-0.7	-0.8	-0.7	0.7	-0.8	-0.7	-1.0	-0.8	-0.8	-0.7	-0.3	-2.2	-1.6	-2.0	-0.5	-0.8
Age started oral contraceptive pill	0.8	1.0	2.3	-0.9	-1.0	-1.2	-1.0	-0.8	-1.0	-1.0	-1.0	-1.5	-0.6	-1.1	-1.1	-0.0	-1.1	-0.9	-0.5	-1.1	-1.1	-1.1	-1.0	-1.5	-0.0	-1.0	-0.6	-1.5
Number of treatments/medications taken	0.7	1.3	4.3	1.8	1.3	0.9	1.5	0.9	0.6	0.6	0.7	0.6	1.2	1.5	1.1	1.6	0.8	0.7	2.1	1.1	0.8	1.0	0.6	-1.4	0.4	1.9	0.6	-0.2
Average weekly spirits intake	0.7	0.9	2.3	-0.5	-1.5	-1.0	-1.3	-0.8	-0.8	-0.7	-1.0	-1.5	-0.9	-1.3	-1.1	0.1	-1.1	-0.6	-1.1	-1.4	-1.0	-1.1	-0.5	-0.2	-0.4	-0.4	-0.8	-0.5
Medication: Metformin	0.7	1.0	3.6	0.8	1.2	1.2	1.9	0.5	1.3	0.8	0.9	0.9	0.8	1.2	1.2	1.2	1.0	0.7	0.8	0.9	0.6	0.9	0.5	0.1	0.0	1.8	0.8	1.0
Serious illness, injury or assault to yourself	0.7	0.8	2.0	-0.8	-1.0	-1.0	-0.6	-0.4	-1.1	-0.8	-1.1	-1.4	-0.4	-1.0	-1.0	0.5	-1.0	-0.9	-1.0	-1.1	-0.4	-0.9	-1.0	-0.7	-0.4	-1.0	-0.4	-1.2
Heel bone mineral density (BMD) T-score, automated (right)	0.7	1.5	3.1	-1.3	-1.3	-1.2	-1.1	-1.4	-1.1	-1.2	-1.4	-1.3	-1.0	-1.2	-1.3	-0.7	-1.4	-1.1	-1.5	-1.4	-1.1	-1.4	-1.7	0.4	-1.5	0.3	-1.4	-1.1
Medication: Ibuprofen	0.7	0.9	1.8	1.1	1.2	0.5	0.8	1.0	0.5	0.5	0.6	0.9	1.2	1.1	1.0	1.3	0.8	0.2	1.3	1.1	0.8	0.9	0.7	-1.0	0.5	1.1	1.2	0.1
Leg pain on walking	0.7	0.9	1.8	-1.0	-1.1	-1.0	-1.1	-1.3	-0.8	-0.7	-0.6	-1.3	-0.8	-1.1	-1.0	-0.6	-0.9	-0.8	-1.2	-1.1	-0.6	-1.0	-0.5	-1.1	-1.0	0.6	-0.7	-0.5
Eye problems/disorders: Cataract	0.7	0.8	2.7	-1.3	-1.0	-0.9	-1.4	-0.6	-0.5	-0.7	-0.6	-0.6	-1.0	-1.1	-1.0	-0.5	-0.8	-0.8	-1.2	-0.9	-0.6	-1.0	-0.9	0.8	-0.6	-1.6	-0.6	-0.0
Medication: Gliclazide	0.7	0.8	1.9	0.7	0.9	1.1	1.4	0.7	1.0	0.7	0.8	0.9	0.8	0.9	1.0	0.1	0.8	1.2	0.5	0.8	0.6	0.8	0.8	1.3	0.3	0.1	1.1	1.3
Supplements: Fish oil (including cod liver oil)	0.7	0.9	1.9	1.3	0.7	0.8	0.7	1.0	0.6	0.9	0.5	0.6	0.8	0.8	0.9	1.4	0.9	1.1	0.8	0.8	0.8	0.7	1.2	0.4	1.4	1.2	1.1	1.1
Fasting Glucose	0.6	0.8	2.4	-1.1	-0.7	-0.7	-0.5	-0.8	-1.0	-1.2	-1.0	-0.4	-0.9	-0.8	-0.8	-0.3	-0.8	-1.5	-1.0	-0.7	-1.2	-0.9	-1.2	0.6	-0.3	0.2	-1.1	-0.8
LDL Cholesterol	0.6	0.9	1.8	-1.0	-0.5	-0.9	-0.5	-1.1	-0.9	-1.3	-1.3	-0.2	-1.0	-0.6	-0.8	-0.5	-1.0	-1.0	-0.9	-0.7	-1.2	-1.0	-1.1	0.4	-1.2	-1.2	-1.3	-1.2
Tanning	0.6	6.8	12.0	-3.5	-2.2	-2.8	-1.8	-2.4	-2.7	-3.1	-3.0	-2.5	-1.8	-2.4	-2.9	-1.0	-2.9	-3.1	-2.0	-2.6	-2.8	-3.0	-2.9	-1.2	-3.2	-1.3	-3.0	-3.0
Ever had hysterectomy (womb removed)	0.6	0.7	1.7	0.8	0.4	0.9	0.4	1.3	1.0	1.1	0.9	0.4	0.9	0.6	0.8	-0.0	0.9	1.0	0.7	0.6	1.2	0.7	0.6	0.6	1.3	0.2	1.0	0.8
Vitamin and mineral supplements	0.6	0.8	2.6	1.0	0.3	1.0	0.2	1.0	1.5	1.4	1.6	0.1	0.3	0.6	0.7	0.1	1.1	1.1	0.6	0.8	1.2	0.9	0.9	-0.7	0.7	-0.3	0.9	0.9
Past tobacco smoking	0.6	1.1	2.5	-0.4	-1.1	-1.3	-1.1	-1.1	-1.2	-1.0	-0.9	-1.3	-0.8	-1.3	-1.1	-0.3	-1.2	-0.9	-1.0	-1.2	-1.0	-1.2	-1.1	-0.9	-0.6	-1.6	-0.4	-0.9
Hip circumference	0.6	2.6	4.5	-1.7	-1.5	-1.6	-1.8	-1.8	-1.5	-1.6	-1.6	-1.0	-1.4	-1.5	-1.8	-1.7	-1.5	-1.9	-1.9	-1.3	-1.7	-1.6	-1.5	-0.1	-2.0	-0.6	-2.0	-2.1
Noisy workplace	0.6	0.8	2.6	-1.1	-1.2	-0.9	-1.6	-1.1	-0.3	-0.6	-0.5	-0.6	-0.9	-1.2	-0.9	-0.8	-0.7	-0.6	-1.2	-0.8	-0.5	-0.8	-0.1	0.5	-1.2	-1.1	-0.9	-0.6
Lung cancer (father)	0.6	0.7	1.5	-0.5	-0.6	-0.8	-0.2	-0.8	-0.9	-1.1	-1.1	-0.9	-0.2	-0.8	-0.8	0.4	-1.0	-0.9	-0.5	-1.0	-0.8	-1.1	-0.8	-0.2	-1.2	-0.1	-1.2	-1.1
Overall health rating	0.6	1.3	2.6	1.1	0.6	1.2	0.9	1.5	1.3	1.4	1.2	-0.0	1.6	1.0	1.1	1.4	1.1	0.5	1.3	0.9	1.4	1.0	1.5	-1.3	0.8	1.1	1.0	0.3
Illnesses of father: Heart disease	0.6	0.8	1.9	-0.1	-0.6	-0.9	-0.6	-1.4	-1.0	-1.3	-1.2	-0.6	-0.7	-0.7	-0.9	-1.0	-1.0	-0.7	-1.1	-0.8	-1.3	-1.0	-0.7	-0.3	-1.1	0.4	-1.1	-0.8
Friendships satisfaction	0.6	0.8	2.0	-0.7	-1.1	-0.8	-0.7	-0.7	-0.5	-0.7	-0.6	-1.4	-1.2	-0.8	-0.9	-0.4	-0.9	-1.0	-1.0	-1.1	-0.6	-1.0	-0.5	-1.3	-1.1	-0.1	-0.5	-1.1
Medication for cholesterol	0.6	0.8	3.6	-0.8	-1.1	-0.8	-1.1	-0.8	-0.6	-0.3	-0.6	-0.6	-0.8	-1.3	-0.9	-0.2	-0.7	0.0	-1.6	-0.9	-0.6	-0.8	-0.7	1.7	-0.3	-1.9	-0.0	0.7
Unable to work because of sickness or disability	0.6	0.8	2.7	-1.1	-0.8	-1.0	-0.6	-0.6	-1.3	-0.9	-1.0	-0.8	-0.8	-0.8	-0.9	-0.2	-0.9	-1.3	-0.8	-0.8	-0.7	-0.9	-0.9	-0.9	-0.3	0.1	-1.0	-1.6
Myopia	0.6	0.8	2.7	0.7	0.5	1.2	1.1	0.8	0.8	1.4	1.1	-0.2	1.1	0.9	0.9	0.5	0.9	0.5	0.8	0.5	1.4	0.8	0.8	-0.9	1.6	0.7	1.0	0.5
Cholesterol lowering medication	0.6	0.9	2.6	0.8	1.2	1.0	1.2	1.1	0.8	0.8	0.9	0.8	1.0	1.3	1.2	1.3	1.0	0.1	1.6	1.1	0.9	1.0	0.7	-0.7	0.4	0.5	0.7	0.4
Major Depression (MDD)	0.5	0.6	2.9	-0.5	0.2	-0.6	-0.0	-0.9	-0.6	-0.9	-0.8	-0.0	0.3	-0.2	-0.2	-0.4	-0.7	-1.4	-0.3	-0.3	-0.9	-0.5	-0.7	-0.6	-1.7	-1.6	-0.9	-0.8
Verbal and Numeric Reasoning (VNR)	0.5	1.1	6.1	0.9	0.9	0.8	1.2	0.9	0.8	1.0	0.9	0.4	1.0	0.8	0.8	1.6	0.8	0.6	0.8	0.9	1.0	0.8	0.9	-0.3	0.9	2.5	1.1	1.5
Rheumatoid Arthritis	0.5	0.7	2.0	-0.6	-1.2	-0.8	-0.9	-0.8	-0.8	-0.6	-0.5	-1.4	-1.0	-1.0	-1.0	-0.3	-0.9	-0.8	-0.5	-1.1	-0.7	-0.9	-0.6	-0.8	-0.6	-0.4	-0.6	-0.9
Other serious medical condition/disability diagnosed by doctor	0.5	0.7	2.0	1.1	0.7	1.0	1.1	0.7	0.4	0.8	0.8	0.3	1.0	0.8	0.9	0.9	0.8	0.5	0.9	0.6	0.8	0.8	1.0	-0.3	1.4	0.5	0.5	0.5
Average weekly fortified wine intake	0.5	0.6	1.2	-1.0	-1.0	-0.9	-0.9	-0.4	-0.5	-0.6	-0.9	-0.7	-0.6	-0.9	-0.9	-0.7	-0.8	-1.0	-0.7	-0.9	-0.5	-0.9	-1.1	0.5	-0.3	-0.7	-0.5	-0.7
Maternal smoking around birth	0.5	0.7	2.0	-1.1	-1.0	-0.9	-1.4	-0.8	-0.5	-0.5	-0.6	-0.6	-0.7	-1.1	-0.9	-0.4	-0.6	-0.8	-1.1	-0.7	-0.5	-0.7	-0.3	0.1	-1.0	-1.3	-0.8	-1.0
Multivitamins +/- minerals	0.5	0.6	1.7	-1.2	-0.5	-0.7	-0.3	-0.6	-1.3	-0.9	-1.2	-0.7	-0.3	-0.6	-0.6	-0.1	-0.9	-1.1	-0.7	-0.8	-0.8	-0.9	-1.0	-0.0	-0.2	-0.1	-0.5	-1.1
Chronic bronchitis/emphysema (father)	0.5	0.6	1.5	-0.7	-0.8	-0.7	-0.9	-0.8	-0.7	-0.5	-0.6	-0.8	-1.1	-0.8	-0.9	-0.7	-0.6	-0.9	-0.9	-0.7	-0.8	-0.7	-0.4	-0.5	-1.2	-0.1	-0.9	-0.0
Body mass index (BMI)	0.5	2.1	3.9	-1.5	-1.3	-1.6	-1.5	-2.0	-1.7	-1.5	-1.7	-0.6	-1.1	-1.5	-1.6	-0.8	-1.5	-1.9	-1.7	-1.2	-1.5	-1.5	-1.4	0.8	-1.7	-0.2	-1.5	-1.6
Number of incorrect matches in round	0.5	0.8	1.9	-0.7	-0.8	-0.9	-0.7	-0.8	-1.2	-1.0	-0.8	-0.4	-0.5	-0.8	-0.8	0.2	-1.0	-0.1	-0.5	-1.1	-1.0	-1.0	-1.0	1.4	-0.8	-1.3	-1.0	-0.5
Pulse rate	0.5	0.9	3.2	-1.0	-1.4	-1.0	-1.2	-0.7	-0.7	-0.4	-0.7	-1.8	-1.1	-1.2	-1.3	-0.4	-0.9	-0.6	-0.8	-1.2	0.0	-0.9	-0.6	-1.0	-0.5	0.5	-0.0	-0.7
Forced expiratory volume in 1-second (FEV1), Best measure	0.5	1.6	6.7	-1.5	-1.8	-0.9	-2.0	-0.6	-0.8	-0.6	-0.9	-1.6	-1.4	-1.5	-1.3	-2.6	-1.0	-1.0	-1.1	-1.4	-0.9	-1.2	-0.6	-0.6	-0.7	-0.6	-1.4	-0.8
Impedance of arm (left)	0.5	2.4	5.7	1.6	1.2	1.5	1.0	2.2	1.8	1.5	1.8	0.8	1.0	1.5	1.8	0.6	1.5	2.4	2.1	1.3	1.6	1.4	1.7	-1.1	1.8	1.4	1.1	1.4
Seen doctor (GP) for nerves, anxiety, tension or depression	0.5	0.7	2.2	1.1	0.6	1.0	0.8	0.4	0.6	1.0	1.1	0.5	1.0	0.7	1.0	1.1	0.9	0.6	0.4	0.8	1.0	0.9	0.9	-0.1	0.6	0.8	0.6	1.5
Emphysema/chronic bronchitis	0.5	0.6	1.3	0.6	0.9	0.7	0.7	0.9	1.0	0.4	0.6	1.1	0.4	0.8	0.8	0.8	0.7	0.7	1.0	1.0	0.1	0.7	0.5	0.4	0.9	1.0	0.0	0.4
Pulse rate, automated reading	0.5	1.7	3.3	-1.5	-1.6	-1.5	-1.8	-1.1	-1.2	-1.1	-1.1	-1.7	-1.4	-1.7	-1.8	-0.1	-1.3	-1.4	-1.5	-1.3	-1.0	-1.4	-0.9	-1.1	-1.2	0.7	-0.8	-0.9
Whole body fat-free mass	0.5	2.8	7.2	-2.4	-1.4	-1.3	-1.6	-1.6	-1.6	-1.5	-1.6	-1.1	-1.0	-1.3	-1.7	-1.7	-1.5	-2.4	-1.8	-1.3	-1.8	-1.7	-1.5	-0.4	-2.1	-0.8	-2.3	-2.7
Long-standing illness, disability or infirmity	0.5	0.8	3.5	1.4	0.6	0.7	1.3	0.5	0.5	0.8	0.9	-0.0	0.9	0.9	0.6	1.9	0.6	0.9	0.8	0.5	0.7	0.6	0.6	-0.9	1.3	0.6	0.8	0.3
Whole body water mass	0.5	2.8	7.0	-2.4	-1.4	-1.4	-1.6	-1.6	-1.6	-1.5	-1.6	-1.1	-1.0	-1.3	-1.7	-1.7	-1.5	-2.3	-1.8	-1.3	-1.8	-1.7	-1.5	-0.3	-2.1	-0.9	-2.2	-2.6
Guilty feelings	0.5	0.8	1.6	-0.6	-0.7	-0.9	-0.4	-0.6	-0.8	-0.9	-1.0	-1.2	-0.5	-0.9	-0.9	0.1	-1.0	-1.3	-0.7	-0.9	-0.8	-0.8	-1.1	-1.1	-1.1	1.1	-0.9	-0.3
Wears glasses or contact lenses	0.5	0.5	1.9	1.0	1.1	0.5	1.4	0.3	0.2	0.2	0.4	0.9	0.7	1.0	0.9	1.2	0.5	0.3	1.2	0.7	0.3	0.6	0.4	-0.0	0.5	-0.5	0.6	0.3
Schizophrenia (2018)	0.4	0.8	7.6	-0.6	-0.3	-0.8	0.2	-0.9	-1.1	-1.0	-0.8	-0.6	0.2	-0.4	-0.8	-0.3	-0.9	-0.6	-0.9	-0.8	-0.8	-0.9	-0.5	-0.4	-1.0	2.7	-1.3	-0.6
Schizophrenia vs Biploar Disorder	0.4	0.6	2.4	0.5	0.0	0.5	0.0	0.9	1.1	1.3	1.1	0.1	0.0	0.2	0.3	0.5	0.7	1.1	0.1	0.4	1.0	0.8	0.9	0.1	0.3	0.3	1.6	1.1
Prostate Cancer	0.4	0.6	2.3	0.5	0.1	0.9	0.4	0.8	1.0	1.2	0.8	0.3	0.4	0.2	0.4	-0.2	0.7	0.7	0.1	0.4	1.2	0.5	0.9	1.3	1.5	1.0	0.6	1.1
Ulcerative Colitis	0.4	0.6	6.8	-0.0	0.9	0.0	0.7	-0.3	-0.1	-0.2	0.1	1.7	0.2	0.6	0.2	0.7	0.2	0.7	0.0	0.6	0.1	0.4	-0.2	2.6	0.7	1.3	-0.6	-0.3
Chronotype (morning person)	0.4	1.0	5.3	0.4	1.9	0.6	2.3	-0.3	-0.2	-0.4	0.2	1.5	0.8	1.6	1.0	0.9	0.5	-0.7	1.1	1.1	-0.6	0.8	-0.1	-0.6	-0.2	1.7	-0.1	-0.2
Medication for hormone replacement therapy	0.4	0.4	2.4	0.5	1.1	0.2	0.7	-0.3	0.2	-0.4	0.0	1.0	0.2	0.7	0.7	-0.7	0.3	0.3	0.4	0.8	-0.2	0.4	0.3	-1.5	-0.4	1.2	-0.3	0.4
Supplements: Zinc	0.4	0.4	1.7	-0.7	0.3	-0.3	0.4	-0.5	-0.6	-0.8	-0.9	0.7	0.1	0.0	-0.2	-0.6	-0.4	-0.2	-0.5	0.0	-0.7	-0.3	-0.9	1.2	0.0	-1.3	-0.8	-0.7
Medication: Co-codamol	0.4	0.5	1.1	1.0	-0.1	0.5	0.4	0.5	0.8	0.9	0.9	-0.5	0.9	0.2	0.4	0.5	0.4	1.1	0.5	0.1	1.1	0.4	1.0	-0.7	0.8	-1.0	0.6	0.7
Heel bone mineral density (BMD) T-score, automated (left)	0.4	0.9	1.5	-0.9	-1.0	-1.0	-1.0	-1.1	-0.7	-1.1	-1.1	-0.8	-0.9	-1.0	-1.1	-0.2	-1.0	-0.6	-1.1	-1.0	-0.9	-1.0	-1.2	0.4	-1.2	0.3	-1.1	-0.8
Had menopause	0.4	0.4	1.3	-0.2	-0.5	-0.7	-0.3	-0.6	-0.5	-0.8	-0.8	-0.8	-0.3	-0.6	-0.6	-0.5	-0.8	-0.2	-0.3	-0.7	-1.0	-0.7	-0.8	-0.8	0.0	-0.6	-1.1	-0.9
Forced vital capacity (FVC)	0.4	1.7	5.7	-1.5	-2.0	-0.9	-1.9	-0.7	-0.9	-0.6	-0.8	-1.7	-1.5	-1.7	-1.5	-2.4	-1.1	-0.7	-1.4	-1.6	-1.0	-1.3	-1.0	0.0	-0.6	-0.8	-1.5	-0.8
Diabetes (self-reported)	0.4	0.7	2.7	0.8	0.6	1.1	1.1	0.6	1.2	1.0	0.9	0.4	0.5	0.7	0.7	-0.4	0.8	0.7	0.2	0.5	0.8	0.7	0.9	0.3	0.3	1.6	0.7	1.1
Number of live births	0.4	0.6	3.3	-0.2	0.4	-0.4	0.2	-0.3	-0.8	-1.0	-1.0	0.7	0.3	0.1	-0.1	-1.0	-0.5	-0.3	-0.2	0.0	-1.3	-0.3	-0.6	0.9	-1.1	-1.8	-1.2	-0.9
Forced expiratory volume in 1-second (FEV1)	0.4	1.3	4.1	-1.2	-1.9	-0.8	-1.9	-0.4	-0.8	-0.4	-0.7	-1.5	-1.3	-1.5	-1.3	-2.0	-0.9	-0.6	-1.2	-1.4	-0.8	-1.1	-0.7	0.2	-0.5	-0.3	-1.1	-0.4
Medication: Ibuprofen (e.g. Nurofen)	0.4	0.5	1.7	0.4	0.6	0.3	-0.0	1.0	0.6	0.5	0.4	0.4	0.9	0.6	0.6	0.7	0.6	0.2	0.9	0.7	0.8	0.6	0.6	-0.8	0.1	1.3	1.1	-0.1
Hair/balding pattern: Pattern 4	0.4	0.9	2.3	0.8	1.5	0.6	1.3	0.8	0.5	0.3	0.5	1.3	1.3	1.2	1.3	1.2	0.7	0.9	1.5	1.1	0.4	1.0	0.4	0.2	0.5	-0.5	0.9	0.3
Qualifications: O levels/GCSEs or equivalent	0.4	0.6	3.9	-0.4	0.0	-0.7	0.4	-0.5	-0.4	-0.9	-0.7	-0.8	0.3	-0.2	-0.4	0.3	-0.7	-0.9	-0.4	-0.4	-0.6	-0.7	-1.2	-2.0	-1.4	0.5	-0.7	-1.0
Hypothyroidism/myxoedema (self-reported)	0.4	0.7	3.0	1.0	0.7	0.7	0.9	0.7	0.5	0.8	0.8	0.4	1.2	0.7	0.7	1.2	0.8	0.8	0.9	0.7	0.8	0.9	0.7	0.0	1.7	-0.6	1.1	0.6
Medication: Amlodipine	0.4	0.6	5.0	0.4	0.8	0.7	0.6	0.4	0.7	0.6	0.6	0.7	0.0	1.0	0.7	-0.4	0.7	0.6	0.8	0.8	0.6	0.9	0.5	-0.2	0.0	2.2	0.3	-0.2
Health satisfaction	0.4	0.6	9.8	-0.7	0.1	-0.1	-0.2	-0.3	-0.1	-0.2	-0.1	-0.5	-0.5	-0.0	0.1	-0.2	-0.0	-0.3	-0.3	0.1	-0.1	-0.1	0.0	-3.1	-1.4	-0.7	-0.2	-0.4
Eye problems/disorders: None of the above	0.4	0.5	3.0	0.8	-0.1	0.6	-0.4	0.4	0.5	0.9	0.5	-0.0	0.0	0.3	0.5	-1.7	0.6	1.3	0.5	0.3	0.7	0.5	0.9	-0.5	1.1	0.4	0.3	0.6
Qualifications: NVQ or HND or HNC or equivalent	0.4	0.5	1.2	-0.5	-0.9	-0.8	-0.6	-1.1	-0.5	-0.5	-0.5	-1.1	-0.6	-0.9	-0.7	-0.6	-0.7	-0.2	-0.7	-0.9	-0.5	-0.7	-0.6	-0.8	-0.6	-0.9	-0.5	-0.1
Mineral and other dietary supplements	0.4	0.5	1.1	0.4	0.9	0.7	0.6	0.5	1.0	0.6	1.0	1.0	0.6	0.8	0.8	0.0	0.8	0.4	0.9	1.0	0.8	0.9	0.4	0.1	0.5	-0.4	0.3	0.3
Illnesses of father: None of the above (group 1)	0.4	0.4	1.0	-1.0	-0.7	-0.8	-0.5	-0.3	-0.8	-0.7	-0.7	-0.6	-0.4	-0.8	-0.7	-0.3	-0.7	-0.8	-0.7	-0.7	-0.6	-0.7	-0.8	-0.4	-0.5	-0.8	-0.4	-0.3
Arm fat mass (left)	0.4	1.4	3.0	-1.4	-1.0	-1.2	-1.4	-1.4	-1.4	-1.2	-1.3	-0.5	-0.8	-1.1	-1.2	-1.0	-1.1	-1.6	-1.3	-0.9	-1.2	-1.2	-1.2	0.3	-1.4	0.1	-1.6	-1.7
Medication: Paracetamol	0.4	0.5	1.6	-0.2	0.1	-0.8	-0.1	-0.2	-1.2	-1.2	-1.1	0.5	0.4	-0.2	-0.4	1.1	-0.7	-0.7	0.3	-0.2	-0.9	-0.5	-0.5	1.3	-0.2	0.7	-0.7	-1.2
Ever smoked	0.4	0.6	2.8	-0.1	1.0	0.9	0.8	0.7	1.1	0.6	0.6	1.3	0.5	1.1	0.7	-0.1	0.9	0.4	0.5	1.0	0.5	0.9	0.5	0.4	0.5	1.7	-0.1	0.2
Basal metabolic rate	0.4	2.5	6.7	-2.2	-1.3	-1.2	-1.6	-1.5	-1.5	-1.4	-1.5	-1.0	-0.8	-1.2	-1.6	-1.7	-1.4	-2.3	-1.7	-1.2	-1.6	-1.6	-1.4	-0.3	-1.9	-0.6	-2.2	-2.6
Intelligence (Savage-Jansen 2018)	0.3	0.9	3.0	-0.8	-0.3	-1.1	-0.3	-1.3	-0.7	-0.8	-1.0	-0.9	-0.8	-0.7	-0.8	0.7	-1.0	-1.0	-1.1	-0.8	-0.9	-1.0	-0.9	-1.7	-1.2	1.4	-0.7	-0.2
Alzheimer’s Disease (in father)	0.3	0.3	2.3	0.4	0.7	0.5	0.5	-0.1	0.5	0.2	0.3	0.7	0.6	0.5	0.5	0.0	0.4	0.4	0.4	0.4	0.2	0.2	-0.3	0.9	1.5	-0.6	0.2	0.4
Breast Cancer	0.3	0.6	2.7	-1.3	-1.1	-0.6	-1.2	-0.4	-0.5	-0.6	-0.5	-0.7	-0.9	-1.0	-0.7	-1.7	-0.6	-0.7	-0.9	-0.8	-0.5	-0.7	-0.6	0.7	0.1	-0.4	-0.5	-0.1
Blood Eosinophil Count	0.3	2.1	4.5	1.3	1.6	1.5	1.3	1.5	1.4	1.3	1.4	1.8	1.8	1.7	1.5	0.7	1.5	1.4	1.7	1.7	1.2	1.6	1.2	1.0	2.1	1.4	0.6	0.8
Hair Pigment	0.3	8.3	32.2	2.4	2.3	3.2	2.3	3.6	3.3	3.4	3.2	2.4	2.6	2.7	2.8	0.4	3.2	4.0	2.6	2.8	3.5	2.8	3.4	1.2	5.7	-0.2	1.1	0.9
Relative age of first facial hair	0.3	0.5	2.6	1.1	0.6	0.7	0.8	0.8	0.6	0.7	0.7	0.3	1.1	0.6	0.5	1.6	0.7	0.4	0.4	0.4	0.6	0.6	0.6	0.1	1.1	-0.0	0.8	0.3
Ever used hormone-replacement therapy (HRT)	0.3	0.4	1.7	0.8	0.6	0.7	0.7	0.2	0.6	0.4	0.5	0.3	0.2	0.6	0.7	-0.8	0.5	0.7	0.5	0.5	0.2	0.6	0.7	-1.0	0.4	1.3	0.3	0.7
Eye problems/disorders: Diabetes related eye disease	0.3	0.3	3.7	0.3	0.4	-0.0	0.6	0.4	-0.2	-0.1	-0.0	0.3	0.9	0.1	0.0	1.9	0.0	0.5	0.1	0.1	-0.1	0.0	-0.1	1.2	-0.0	0.8	0.6	0.0
Hand grip strength (right)	0.3	0.7	1.4	0.3	0.8	1.1	0.7	0.9	0.9	0.8	0.6	1.1	0.9	1.2	0.9	0.5	0.9	0.4	1.2	1.0	0.5	0.9	0.5	1.2	1.0	-0.7	0.7	0.9
Taking other prescription medications	0.3	0.5	3.9	0.1	-0.1	-0.4	0.1	-0.3	-0.4	-0.5	-0.3	-0.5	-0.1	-0.0	-0.2	1.1	-0.3	-0.3	0.2	-0.0	-0.2	-0.2	-0.4	-2.0	-1.0	-1.7	-0.7	-0.7
Hayfever, allergic rhinitis or eczema	0.3	0.7	1.4	-0.9	-1.0	-0.8	-0.9	-0.7	-0.5	-0.7	-0.8	-1.1	-0.8	-0.9	-0.9	-0.8	-0.9	-1.0	-0.2	-0.9	-0.8	-1.0	-0.7	-0.9	-0.6	-0.9	-1.1	-1.2
Ever unenthusiastic/disinterested for a whole week	0.3	0.4	1.1	-0.6	-0.6	-0.7	-0.8	-0.6	-0.5	-0.6	-0.4	-0.7	-0.1	-0.6	-0.6	-0.0	-0.6	-0.1	-0.3	-0.7	-0.6	-0.5	-0.4	-0.6	-0.6	-1.0	-1.0	-0.7
Impedance of arm (right)	0.3	1.5	4.3	1.1	0.8	1.1	0.6	2.1	1.4	1.1	1.5	0.4	0.8	1.1	1.3	0.4	1.1	1.9	1.8	0.9	1.3	1.0	1.3	-1.2	1.4	1.3	0.7	0.8
Arm fat mass (right)	0.3	1.3	3.1	-1.4	-1.1	-1.1	-1.4	-1.2	-1.2	-1.1	-1.2	-0.6	-0.7	-1.1	-1.2	-1.0	-1.1	-1.5	-1.2	-0.9	-1.0	-1.2	-1.0	0.2	-1.3	0.2	-1.5	-1.8
Trunk predicted mass	0.3	1.6	4.8	-1.9	-0.9	-0.9	-1.2	-1.3	-1.2	-1.1	-1.2	-0.5	-0.6	-0.8	-1.3	-1.5	-1.0	-1.8	-1.4	-0.8	-1.3	-1.2	-1.1	0.1	-1.6	-0.5	-2.0	-2.2
Pulse wave reflection index	0.3	0.3	1.4	0.8	0.2	0.8	0.2	1.0	0.9	0.8	0.7	0.1	0.8	0.5	0.3	0.2	0.6	0.4	0.1	0.5	0.6	0.4	1.2	-0.1	0.5	0.3	-0.0	0.4
Arm fat-free mass (right)	0.3	1.3	3.4	-1.6	-0.9	-0.7	-1.0	-1.3	-1.0	-0.9	-1.0	-0.5	-0.6	-0.8	-1.1	-1.2	-0.9	-1.8	-1.4	-0.8	-1.2	-1.1	-1.2	0.1	-1.3	-1.4	-1.6	-1.8
Exposure to tobacco smoke outside home	0.3	0.3	2.0	-0.6	-0.4	-0.5	0.0	-0.1	-0.3	-0.6	-0.4	-0.2	-0.0	-0.5	-0.7	-0.6	-0.6	0.1	-0.4	-0.7	-0.5	-0.6	-0.7	0.9	-0.3	-1.4	-0.5	-0.7
Number of full brothers	0.3	0.4	1.6	-0.1	-1.1	-0.5	-1.3	-0.2	-0.5	-0.1	-0.2	-0.9	-1.0	-1.0	-0.7	-0.6	-0.5	-0.2	-0.6	-0.7	-0.1	-0.3	-0.3	-0.4	-0.2	0.6	-0.4	0.2
Number of children fathered	0.3	0.3	1.4	0.3	0.3	0.5	0.5	0.4	0.2	0.5	0.4	0.5	0.6	0.3	0.5	0.1	0.4	0.3	-0.1	0.3	0.4	0.5	0.9	1.2	1.2	0.9	0.2	1.0
Arm predicted mass (right)	0.3	1.3	3.6	-1.6	-0.7	-0.7	-0.9	-1.3	-1.0	-1.0	-1.0	-0.4	-0.5	-0.7	-1.1	-1.1	-0.9	-1.9	-1.3	-0.7	-1.2	-1.0	-1.2	0.1	-1.3	-1.0	-1.7	-1.8
Alcohol intake frequency.	0.3	0.8	1.7	1.3	0.9	0.7	0.8	1.0	0.3	0.7	0.9	0.8	0.9	0.9	1.0	0.9	0.8	0.3	1.0	0.8	0.8	0.7	1.1	0.6	0.8	-1.3	1.3	0.6
Chest pain or discomfort	0.3	0.4	5.3	-0.1	-0.3	-0.2	-0.6	-0.6	-0.1	-0.2	-0.4	-1.1	-0.0	-0.0	-0.0	0.3	-0.3	-0.7	0.1	-0.3	0.1	-0.4	0.0	-2.3	-1.2	-0.3	-0.6	-0.6
Age at last live birth	0.3	0.4	1.1	0.5	1.0	0.7	0.6	0.6	0.5	0.4	0.5	1.0	0.6	1.0	0.8	0.2	0.8	0.7	0.7	1.1	-0.0	0.7	0.4	0.1	-0.1	0.2	0.1	0.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.3	0.4	1.1	-0.9	-0.5	-0.6	-0.9	-0.1	-0.5	-0.4	-0.6	-0.4	-0.6	-0.6	-0.4	-0.6	-0.4	-1.0	-0.5	-0.3	-0.5	-0.4	-0.7	-0.5	-0.3	-1.0	-0.4	-1.0
Diabetes diagnosed by doctor	0.3	0.4	2.8	0.6	0.5	0.8	1.0	0.4	0.9	0.7	0.7	0.3	0.1	0.5	0.7	0.1	0.7	0.5	0.1	0.5	0.5	0.6	0.6	-0.3	0.1	1.7	0.7	1.0
Qualifications: nursing, teaching	0.3	0.4	2.3	-0.6	-0.7	-0.6	-0.8	-0.2	-0.5	-0.4	-0.4	-1.1	-0.3	-0.7	-0.6	-0.4	-0.5	-0.5	-0.8	-0.6	-0.6	-0.7	-0.5	-1.5	-0.9	0.1	-0.4	-0.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.3	0.3	1.7	-0.5	-0.3	-0.3	-0.3	-0.0	-0.3	-0.5	-0.5	-0.2	0.2	-0.3	-0.4	-0.2	-0.4	-1.3	-0.2	-0.3	-0.8	-0.4	-0.1	-0.2	-1.1	1.1	-0.6	-0.9
Osteoporosis (self-reported)	0.3	0.4	6.6	0.4	0.3	0.1	0.2	0.3	0.1	0.3	0.4	-0.4	0.6	0.3	0.2	1.1	0.3	-0.1	0.0	0.3	0.3	0.2	0.5	-2.6	0.1	0.6	0.3	0.0
Financial situation satisfaction	0.3	0.4	0.9	-0.3	0.7	0.6	0.5	0.6	0.7	0.6	0.5	0.6	1.0	0.6	0.6	-0.5	0.7	-0.0	0.1	0.8	0.9	0.7	0.6	-0.7	-0.5	1.0	0.5	-0.5
Arm fat-free mass (left)	0.3	1.4	4.1	-1.6	-0.8	-0.8	-0.9	-1.1	-1.1	-1.0	-1.1	-0.5	-0.4	-0.8	-1.1	-1.2	-0.9	-2.0	-1.3	-0.8	-1.2	-1.1	-1.2	0.0	-1.5	-0.9	-1.7	-2.0
Commuting to job workplace: Cycle	0.3	0.4	3.2	0.0	0.8	0.4	1.0	0.1	0.3	0.3	0.2	0.9	0.3	0.6	0.5	-0.2	0.4	0.7	0.5	0.5	-0.0	0.5	0.2	1.0	0.8	1.8	0.6	0.3
Supplements: Calcium	0.3	0.4	1.4	-0.4	-0.4	-0.6	-0.4	0.1	-0.5	-0.6	-0.7	-0.8	0.2	-0.4	-0.7	0.6	-0.7	-0.9	-0.3	-0.7	-0.7	-0.6	-0.6	-0.7	-0.1	1.1	0.0	-1.2
Basal cell carcinoma (self-reported)	0.3	0.4	4.6	0.7	0.4	0.0	0.5	-0.3	0.1	-0.2	-0.0	0.2	-0.3	0.4	0.3	0.3	0.0	0.6	0.5	0.2	-0.3	0.2	-0.6	-0.7	-0.5	-2.1	0.5	0.9
Bipolar Disorder or Schizophrenia	0.2	0.6	7.1	0.4	1.1	0.2	1.2	-0.2	-0.2	-0.3	-0.0	0.8	1.0	0.8	0.3	-0.1	0.2	-0.0	0.2	0.5	-0.2	0.0	0.4	-0.3	-0.3	2.7	-0.7	0.3
Body Mass Index (BMI) (2010)	0.2	0.3	1.1	-1.1	-0.2	-0.4	-0.4	-0.5	-0.6	-0.4	-0.3	-0.0	-0.3	-0.5	-0.5	-1.0	-0.4	-0.9	-0.6	-0.3	-0.4	-0.2	-0.5	0.6	-0.3	-0.3	-0.3	-0.3
Coronary Artery Disease (CAD)	0.2	0.2	0.6	-0.1	-0.4	-0.2	-0.8	-0.8	-0.2	-0.2	-0.3	-0.3	-0.6	-0.1	-0.3	-0.8	-0.3	0.3	0.0	-0.3	-0.1	-0.4	-0.4	0.5	-0.1	-0.3	-0.7	-0.8
HDL Cholesterol	0.2	0.3	1.1	-1.0	-0.6	-0.4	-0.4	-0.7	-0.3	-0.2	-0.2	-0.4	-1.1	-0.5	-0.4	-0.7	-0.4	-0.2	-0.7	-0.4	-0.3	-0.3	-0.1	0.0	-0.8	-0.7	-0.2	-0.5
Neuroticism (2016)	0.2	0.2	0.9	-0.0	-0.8	0.1	-0.7	0.1	0.2	0.3	0.5	-0.9	-0.4	-0.5	-0.1	-0.5	-0.0	0.1	-0.3	-0.4	0.6	-0.0	0.2	-0.9	0.4	0.6	-0.6	0.5
BMI	0.2	1.4	4.1	-1.2	-0.9	-1.2	-1.2	-1.7	-1.3	-1.2	-1.2	-0.2	-0.8	-1.1	-1.3	-0.6	-1.1	-2.0	-1.5	-0.9	-1.4	-1.1	-1.0	1.2	-1.7	-0.6	-1.0	-0.9
Lung FVC	0.2	0.9	2.9	-1.0	-1.3	-0.8	-1.4	-1.1	-0.9	-0.5	-0.8	-1.1	-1.4	-1.2	-1.1	-1.7	-0.8	-0.4	-1.0	-1.1	-0.6	-0.8	-0.3	0.0	-0.3	-0.8	-0.7	0.3
Hearing difficulty/problems: Yes	0.2	0.3	1.5	0.9	-0.1	0.5	0.4	0.6	1.0	0.6	0.5	-0.1	0.2	0.2	0.2	0.8	0.4	1.2	0.2	0.2	0.7	0.2	0.4	0.5	0.6	0.8	0.3	0.8
Diabetes (father)	0.2	0.2	0.9	0.0	-0.5	0.2	-0.9	0.7	0.5	0.6	0.3	-0.3	0.1	-0.4	-0.1	-0.1	0.2	0.3	-0.2	-0.1	0.7	0.0	0.6	0.7	1.0	0.3	0.7	-0.3
Diabetes (mother)	0.2	0.3	0.8	-0.8	-0.9	0.2	-0.9	-0.0	0.3	0.7	0.5	-0.6	-0.1	-0.6	-0.1	-0.8	0.1	0.2	-0.7	-0.4	0.6	0.1	-0.1	0.8	0.1	0.8	0.1	0.8
Age when periods started (menarche)	0.2	0.4	1.3	0.2	0.4	0.6	0.3	1.1	0.7	0.5	0.5	0.5	0.4	0.7	0.4	0.9	0.5	1.2	0.9	0.5	0.5	0.4	0.8	-0.0	0.7	0.1	0.2	-0.1
Bilateral oophorectomy (both ovaries removed)	0.2	0.3	1.5	-0.4	-0.4	-0.3	-0.5	-0.3	-0.4	-0.3	-0.2	-0.7	-0.4	-0.5	-0.3	-1.1	-0.4	-0.8	-0.5	-0.6	-0.4	-0.5	-0.6	-1.2	-0.1	0.0	-0.5	-0.3
Qualifications: CSEs or equivalent	0.2	0.2	1.2	0.4	0.8	0.3	1.0	-0.2	0.1	-0.3	0.1	1.1	0.1	0.6	0.5	-0.4	0.2	0.5	0.2	0.4	-0.3	0.1	-0.4	0.7	0.3	-0.2	-0.4	0.2
Sitting height	0.2	1.3	2.8	0.4	1.2	1.6	0.9	1.7	1.4	1.2	1.3	1.2	1.2	1.7	1.3	-0.8	1.3	1.0	1.4	1.4	0.9	1.0	1.0	-0.5	1.1	1.2	-0.0	0.2
Alcohol usually taken with meals	0.2	0.3	1.2	0.5	0.9	0.5	0.6	-0.0	0.3	0.2	0.5	1.0	-0.4	0.8	0.7	0.0	0.5	0.5	1.1	0.8	-0.2	0.7	0.4	0.0	0.2	0.4	0.4	0.8
Hearing difficulty/problems with background noise	0.2	0.3	4.0	0.6	-0.3	0.3	-0.2	0.6	0.5	0.5	0.3	-0.2	0.0	0.0	-0.1	0.0	0.2	0.2	0.2	0.0	0.5	0.1	0.4	0.6	0.9	2.0	0.3	0.3
Hair/balding pattern: Pattern 2	0.2	0.3	1.8	-0.4	0.1	-0.5	0.2	-0.4	-0.4	-0.8	-0.6	-0.2	0.0	0.2	-0.3	-0.2	-0.4	-0.8	0.0	-0.0	-0.7	-0.6	-0.5	-1.3	-1.1	-0.4	-0.6	-0.5
Had other major operations	0.2	0.2	2.1	0.3	-0.2	-0.2	-0.1	0.1	-0.3	-0.3	-0.1	-0.4	-0.0	0.0	-0.0	0.7	-0.2	-0.1	0.5	-0.1	-0.1	0.0	-0.5	-1.1	-0.5	-1.5	-0.1	-0.4
Financial difficulties in last 2 years	0.2	0.2	2.3	-0.5	-0.2	0.0	-0.4	0.2	-0.2	0.1	0.1	0.4	0.3	-0.3	0.0	-0.6	0.0	0.0	-0.4	-0.0	-0.0	0.1	-0.3	1.5	0.7	0.9	-0.1	-0.3
Allergy	0.2	0.4	1.3	0.9	0.7	0.6	0.7	0.4	0.3	0.5	0.3	0.5	0.6	0.6	0.5	0.7	0.5	0.6	0.2	0.4	0.5	0.6	0.5	0.5	0.4	0.8	1.2	1.0
Pain all over the body in last month	0.2	0.2	1.3	0.5	-0.3	0.3	-0.2	0.4	0.1	0.6	0.3	-0.2	0.6	-0.1	-0.1	-0.1	0.2	0.6	-0.4	-0.1	0.6	0.0	0.9	1.2	0.8	-0.2	0.7	0.5
Illnesses of siblings	0.2	0.3	1.4	-1.2	-0.0	-0.5	0.1	-0.1	-0.3	-0.6	-0.5	0.1	0.1	-0.4	-0.2	0.6	-0.4	-1.0	-0.5	-0.2	-0.4	-0.6	-0.6	0.2	-1.1	0.1	-0.2	-0.5
Neuroticism score	0.2	0.3	1.5	0.7	0.4	0.6	0.6	0.3	0.4	0.4	0.5	-0.1	0.7	0.6	0.7	0.7	0.4	0.0	0.7	0.4	0.4	0.5	0.1	-1.2	0.6	0.9	-0.0	0.3
Weight	0.2	1.2	3.5	-1.4	-0.8	-0.8	-1.1	-1.1	-1.1	-1.0	-1.1	-0.3	-0.5	-0.7	-1.0	-1.2	-0.9	-1.7	-1.0	-0.7	-1.1	-1.1	-1.0	0.1	-1.4	0.0	-1.7	-1.9
Arm fat percentage (right)	0.2	0.7	1.5	-0.9	-0.8	-0.9	-1.1	-0.9	-1.0	-0.9	-0.9	-0.2	-0.5	-0.9	-0.9	-0.6	-0.8	-0.9	-0.8	-0.6	-0.7	-0.9	-0.8	0.9	-0.8	0.7	-1.2	-1.2
Trunk fat-free mass	0.2	1.4	4.3	-1.8	-0.8	-0.7	-1.1	-1.1	-1.1	-1.0	-1.1	-0.4	-0.5	-0.7	-1.2	-1.5	-0.9	-1.8	-1.3	-0.7	-1.2	-1.0	-1.0	0.1	-1.5	-0.4	-1.9	-2.1
Time employed in main current job	0.2	0.2	1.7	0.4	-0.2	0.1	-0.2	0.5	0.4	0.5	0.3	-0.2	0.2	-0.0	0.0	1.0	0.3	0.6	0.2	0.1	0.5	0.3	0.4	-0.6	0.5	1.3	0.2	0.3
Alcohol intake versus 10 years previously	0.2	0.3	1.0	0.4	0.1	0.5	-0.1	0.3	0.2	0.7	0.5	0.1	-0.1	0.4	0.6	-0.0	0.6	-0.2	0.3	0.5	0.8	0.6	0.9	-1.0	0.9	0.0	0.4	0.2
Serious illness, injury or assault of a close relative in last 2 years	0.2	0.3	0.9	0.0	0.2	0.7	0.2	0.6	0.6	1.0	0.8	0.0	0.2	0.4	0.5	-0.1	0.6	0.1	0.1	0.5	0.9	0.6	0.7	-0.3	0.4	-0.0	0.6	0.0
Mouth/teeth dental problems: Dentures	0.2	0.3	0.7	0.1	0.3	0.5	-0.1	-0.1	0.7	0.6	0.8	0.7	-0.6	0.3	0.4	-0.9	0.7	0.4	0.1	0.7	0.8	0.7	0.5	-0.7	0.1	0.9	0.0	0.9
Illnesses of mother	0.2	0.2	0.8	-0.6	-0.5	-0.3	-0.3	-0.6	-0.8	-0.2	-0.4	-0.4	-0.7	-0.6	-0.3	-0.4	-0.3	-0.6	-0.9	-0.4	-0.2	-0.4	-0.4	-0.0	-0.1	-0.6	0.4	0.5
Pulse wave Arterial Stiffness index	0.2	0.2	1.1	0.4	-0.3	0.4	-0.6	1.0	0.6	0.6	0.4	-0.4	0.4	-0.0	-0.1	-0.4	0.2	0.3	-0.3	0.1	0.7	0.1	1.1	-0.5	0.4	0.4	0.1	-0.1
Exposure to tobacco smoke at home	0.2	0.3	2.0	-0.3	-0.1	-0.4	-0.1	-0.1	-0.4	-0.6	-0.5	-0.3	0.0	-0.2	-0.4	-0.1	-0.4	-0.6	0.2	-0.3	-0.5	-0.3	-0.9	-0.4	-0.8	-1.4	-0.4	-0.9
Peak expiratory flow (PEF)	0.2	0.4	1.5	0.1	-0.3	0.5	-0.6	0.7	0.6	0.9	0.7	0.1	-0.1	-0.1	0.2	-1.2	0.6	0.8	-0.4	0.4	0.6	0.5	0.5	0.1	0.4	-0.7	0.4	1.1
Mouth/teeth dental problems: Bleeding gums	0.2	0.2	1.3	-0.3	-0.7	-0.2	-0.8	-0.2	0.3	0.1	0.2	-0.3	-0.7	-0.6	-0.5	0.0	-0.1	0.1	-0.9	-0.4	0.3	-0.1	-0.0	0.9	0.4	-1.1	0.1	0.0
Medication: Paracetamol	0.2	0.4	1.3	-0.3	-0.1	-0.8	-0.5	-0.2	-0.9	-1.0	-1.0	0.5	-0.0	-0.3	-0.4	0.4	-0.6	-0.7	0.2	-0.2	-0.8	-0.4	-0.4	1.2	-0.5	0.2	-0.6	-0.9
Gout (self-reported)	0.2	0.3	1.4	-0.5	-0.6	-0.3	-0.7	-0.4	0.3	-0.1	-0.2	-0.7	-0.5	-0.5	-0.3	-0.6	-0.3	0.0	-1.0	-0.4	-0.1	-0.4	-0.2	-1.2	-0.9	-0.4	-0.6	-0.0
Forced vital capacity (FVC), Best measure	0.2	0.9	5.2	-1.1	-1.3	-0.4	-1.4	-0.3	-0.3	-0.3	-0.5	-1.2	-0.9	-1.0	-0.9	-2.3	-0.6	-0.6	-0.6	-1.0	-0.6	-0.9	-0.3	-0.6	-0.2	-0.8	-1.3	-0.8
Leg fat percentage (right)	0.2	0.7	5.9	0.9	0.8	0.6	0.4	0.1	0.3	0.4	0.4	1.6	0.9	0.7	0.6	0.4	0.6	0.2	0.6	0.9	0.6	0.7	0.6	2.4	0.8	1.0	0.2	0.9
Comparative body size at age 10	0.2	0.6	1.6	-0.3	-0.5	-1.1	-0.8	-1.0	-1.0	-1.0	-0.8	-0.3	-0.4	-0.8	-0.8	-0.9	-0.8	-0.3	-0.4	-0.6	-1.0	-0.9	-1.3	0.9	-0.1	-0.2	-0.4	-0.7
Age at first live birth	0.2	0.4	1.0	0.3	0.9	0.6	0.6	0.8	0.6	0.5	0.6	0.7	0.2	0.9	0.7	1.0	0.8	0.7	0.8	1.0	0.2	0.6	0.3	-0.6	0.1	0.5	0.3	-0.5
Pulse wave peak to peak time	0.2	0.2	1.2	-0.4	0.4	-0.3	0.6	-0.9	-0.5	-0.5	-0.3	0.5	-0.3	0.1	0.1	0.3	-0.2	-0.3	0.4	-0.0	-0.8	-0.1	-1.1	0.4	-0.5	-0.3	-0.1	-0.0
Shortness of breath walking on level ground	0.2	0.2	2.1	0.1	0.5	0.1	0.8	-0.5	0.1	-0.1	-0.1	-0.0	0.0	0.5	0.3	0.0	0.0	-0.6	0.4	0.2	-0.1	0.2	0.3	-1.5	-0.3	-0.1	0.1	-0.3
Qualifications: College or University degree	0.2	0.5	2.7	0.3	0.7	0.4	1.0	0.8	0.3	0.6	0.3	0.1	0.9	0.7	0.4	1.6	0.5	0.3	0.5	0.5	0.4	0.4	0.3	-0.5	0.3	1.5	1.1	0.1
Medication for pain relief, constipation, heartburn	0.2	0.4	1.6	0.3	0.1	0.5	0.6	-0.5	0.3	0.5	0.7	0.3	-0.3	0.1	0.2	-0.7	0.4	1.1	-0.9	0.2	0.3	0.2	0.3	1.0	0.9	-1.2	0.3	1.3
Medication: Allopurinol	0.2	0.3	3.6	-0.5	-0.3	-0.0	-0.1	-0.4	0.4	0.1	0.0	-0.8	-0.2	-0.2	-0.1	0.4	-0.1	-0.2	-0.6	-0.2	-0.1	-0.1	0.0	-1.9	-1.0	-0.2	0.0	0.2
Medication: Seretide 50 evohaler	0.2	0.3	3.7	0.5	0.4	0.2	0.2	0.2	0.2	-0.0	-0.0	0.3	0.4	0.3	0.3	0.3	0.2	-0.1	0.4	0.4	-0.0	0.4	0.4	-0.7	0.4	1.9	-0.3	-0.3
Number of full sisters	0.2	0.2	1.4	0.4	-0.3	0.3	-0.8	0.3	0.6	0.6	0.3	0.2	-0.3	0.0	0.1	-0.5	0.4	0.6	0.4	0.3	0.1	0.4	0.2	0.4	0.4	-1.2	0.6	0.4
Family relationship satisfaction	0.2	0.2	1.1	-0.7	-0.1	-0.2	0.2	-0.4	0.0	-0.3	-0.3	-0.2	-0.4	-0.2	-0.4	-0.3	-0.3	-0.5	-0.6	-0.2	-0.2	-0.2	-0.7	-0.3	-1.0	-0.9	-0.1	-0.1
Illness, injury, bereavement, stress in last 2 years	0.2	0.3	1.9	0.9	0.5	0.3	0.8	-0.0	0.3	0.3	0.4	0.3	0.1	0.5	0.4	0.8	0.3	0.7	0.6	0.3	0.2	0.3	0.5	-0.1	0.3	-0.7	0.5	1.4
Medication: Aspirin	0.2	0.3	1.3	0.4	0.4	0.4	0.5	0.9	0.7	0.5	0.4	0.1	0.7	0.7	0.6	1.1	0.4	0.3	1.1	0.4	0.5	0.5	0.1	-0.1	0.2	0.9	0.3	-0.3
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.4	1.6	0.1	0.4	0.4	-0.1	0.9	0.7	0.5	0.6	1.1	-0.1	0.5	0.4	-0.4	0.7	0.2	0.4	0.8	0.3	0.5	0.8	0.4	0.9	1.3	0.4	0.2
Arm fat percentage (left)	0.2	0.8	1.6	-1.0	-0.9	-1.0	-1.3	-1.1	-1.0	-1.0	-1.0	-0.3	-0.7	-0.9	-0.9	-0.6	-0.9	-1.0	-0.9	-0.7	-0.8	-1.0	-0.8	0.7	-0.8	0.6	-1.2	-1.1
Average weekly red wine intake	0.2	0.3	1.0	0.8	1.0	0.4	0.6	0.4	0.3	0.1	0.2	0.7	0.5	0.8	0.7	0.8	0.4	0.7	1.0	0.7	-0.0	0.6	0.2	-0.5	0.2	0.2	0.3	0.7
Handedness (chirality/laterality): Left-handed	0.2	0.3	0.8	0.3	0.7	0.5	0.6	0.6	0.7	0.3	0.2	0.5	0.5	0.7	0.4	0.2	0.5	-0.3	0.4	0.6	0.2	0.5	0.0	-0.9	-0.4	-0.6	0.4	-0.7
Commuting to job workplace: Walk	0.2	0.3	3.3	-0.3	0.1	0.2	0.1	0.3	0.3	0.1	0.5	0.4	0.0	0.1	0.2	-0.6	0.2	0.5	-0.5	0.3	0.0	0.1	0.2	1.0	-0.6	-1.8	0.3	-0.0
Breast cancer (self-reported)	0.2	0.2	1.7	0.6	-0.2	-0.0	-0.1	0.4	-0.2	0.1	0.1	0.1	-0.3	-0.1	0.1	-0.3	0.0	0.9	-0.1	-0.2	0.4	0.0	0.1	1.3	1.2	-0.5	0.1	0.6
Average weekly champagne plus white wine intake	0.2	0.3	1.7	0.1	0.5	0.5	0.3	0.2	0.4	0.3	0.3	0.9	-0.1	0.6	0.5	-1.3	0.5	0.5	0.3	0.8	0.4	0.4	0.1	0.6	0.9	0.3	-0.1	0.1
Tinnitus: Yes, now most or all of the time	0.2	0.2	2.4	0.7	0.4	0.1	0.4	-0.2	0.4	-0.1	0.1	0.3	0.2	0.3	0.3	0.6	-0.0	0.3	0.4	0.1	-0.1	-0.1	0.2	0.7	0.0	-1.6	0.1	0.7
Alcohol drinker status: Never	0.2	0.3	1.5	0.1	0.1	-0.5	-0.1	-0.7	-0.9	-0.9	-0.8	-0.2	-0.1	-0.1	-0.2	-0.6	-0.6	-0.4	-0.1	-0.4	-0.8	-0.5	-0.3	-0.1	-0.5	-1.2	-0.3	-0.1
Leg fat percentage (left)	0.2	0.8	6.9	0.9	0.7	0.6	0.4	0.2	0.3	0.4	0.4	1.6	1.0	0.6	0.5	0.5	0.6	0.2	0.6	0.8	0.6	0.6	0.4	2.6	0.8	1.4	0.1	0.8
Number of operations (self-reported)	0.2	0.3	1.6	1.0	0.4	0.4	0.5	0.8	0.4	0.1	0.2	0.3	0.9	0.5	0.4	0.7	0.3	0.6	1.3	0.3	-0.0	0.4	0.3	0.3	0.5	0.9	-0.2	-0.1
Irritability	0.2	0.3	2.2	0.1	-0.8	-0.1	-0.7	-0.1	-0.1	0.3	-0.2	-1.3	-0.3	-0.4	-0.4	-0.2	-0.2	-0.2	-0.3	-0.6	0.3	-0.2	-0.2	-1.5	-0.4	0.7	-0.1	-0.5
Pain experienced in last month	0.2	0.3	1.4	0.7	0.7	0.4	0.8	0.4	0.6	0.5	0.2	0.3	0.6	0.5	0.7	0.8	0.6	0.3	0.6	0.5	0.1	0.5	0.1	-0.2	0.6	-0.1	1.2	0.3
Arm predicted mass (left)	0.2	1.1	3.6	-1.4	-0.6	-0.6	-0.7	-1.0	-1.0	-0.9	-1.0	-0.3	-0.2	-0.6	-1.0	-1.0	-0.8	-1.8	-1.1	-0.6	-1.1	-0.9	-1.0	0.5	-1.2	-0.9	-1.6	-1.9
Alzheimer’s Disease (in mother)	0.1	0.1	0.9	-0.0	0.0	-0.3	-0.2	0.1	-0.3	-0.3	-0.1	-0.3	0.1	0.0	-0.3	0.6	-0.2	-0.2	0.3	-0.1	-0.3	-0.2	-0.2	-0.9	-0.1	-0.0	-0.5	-0.3
Alzheimer’s Disease (including proxy)	0.1	0.1	0.8	0.2	0.3	0.0	-0.0	-0.1	0.1	-0.2	-0.0	0.1	0.2	0.2	-0.0	0.4	-0.0	-0.1	0.4	0.1	-0.4	-0.1	-0.3	-0.1	0.9	-0.6	-0.6	-0.2
Age at First Birth	0.1	0.2	1.5	-0.5	-0.3	-0.3	-0.2	0.0	-0.3	-0.4	-0.5	-0.4	-0.1	-0.3	-0.2	-0.3	-0.2	-0.1	0.0	-0.1	-0.4	-0.3	-0.7	-0.6	-0.3	1.0	-0.6	-1.2
Mean Putamen Volume	0.1	0.1	0.9	0.4	0.0	0.3	0.3	0.1	-0.1	0.4	0.1	-0.2	-0.2	0.1	0.1	0.4	0.3	0.1	0.1	0.1	0.5	0.1	0.5	-0.6	0.2	-1.0	0.3	0.1
Schizophrenia (2014)	0.1	0.2	2.9	-0.2	0.5	-0.1	0.8	-0.1	-0.3	-0.4	-0.1	0.4	0.6	0.4	0.0	0.1	-0.1	-0.4	-0.1	0.0	-0.5	-0.3	0.2	0.3	-0.2	1.7	-0.6	-0.0
Blood White Count	0.1	0.6	8.2	0.9	0.4	0.3	0.3	-0.7	0.4	0.2	0.1	1.2	0.1	0.2	0.1	-0.4	0.2	0.7	-0.5	0.3	-0.0	0.3	0.3	2.9	0.8	1.3	-0.1	0.7
Height	0.1	1.2	3.3	0.1	1.0	1.5	1.0	1.8	1.2	0.6	0.6	0.6	1.2	1.7	1.0	-0.7	0.9	0.2	1.8	0.9	0.6	0.4	0.3	-1.6	-0.1	-0.5	-1.5	-1.8
Smoking Status	0.1	0.2	1.4	-0.6	-0.3	0.2	-0.4	0.1	0.4	0.2	0.0	0.2	-0.2	-0.1	-0.2	-1.2	0.1	0.2	-0.4	-0.0	-0.0	-0.0	0.1	1.1	0.2	0.5	-0.4	0.1
Hypothyroidism (self reported)	0.1	0.3	1.5	0.4	0.4	0.1	0.5	0.3	-0.1	0.1	0.1	0.4	0.7	0.4	0.3	1.2	0.3	0.2	0.6	0.5	-0.0	0.4	-0.0	-0.1	1.1	-1.0	0.5	0.1
Respiratory disease	0.1	0.2	1.2	0.1	0.8	0.1	1.1	-0.2	-0.3	-0.2	0.3	0.6	0.6	0.5	0.4	1.0	0.2	0.1	0.4	0.5	-0.2	0.3	-0.0	-0.3	0.5	0.1	-0.3	0.3
Type 2 Diabetes (T2D) (2018)	0.1	0.3	3.1	0.0	-0.4	-0.0	0.1	-0.5	0.3	-0.0	-0.2	-0.3	-0.8	-0.4	-0.4	-0.7	-0.2	-0.0	-0.8	-0.4	-0.1	-0.3	-0.2	0.5	-0.5	1.7	-0.2	0.1
Lung FEV1/FVC ratio	0.1	0.7	2.2	-0.8	-1.1	-1.0	-1.5	-0.6	-0.9	-0.7	-0.9	-0.4	-1.0	-1.2	-0.9	-0.5	-0.7	-1.0	-1.0	-0.7	-0.6	-0.7	-0.7	0.5	-0.9	-1.2	-0.5	-0.0
Hand grip strength (left)	0.1	0.2	1.0	0.1	0.1	0.6	0.1	0.9	0.5	0.5	0.3	0.4	0.1	0.6	0.2	0.4	0.5	0.2	1.0	0.4	0.4	0.4	0.2	0.6	0.1	-0.8	0.3	0.2
Fed-up feelings	0.1	0.1	1.0	0.2	-0.2	0.2	-0.1	0.0	-0.1	0.2	0.2	-0.6	0.6	-0.1	0.2	-0.3	-0.0	-0.0	0.1	-0.2	0.3	-0.0	-0.1	-0.8	1.0	-0.5	-0.3	-0.3
Relative age voice broke	0.1	0.2	1.5	0.1	-0.2	0.1	-0.1	0.6	-0.0	0.2	0.1	-0.1	0.6	-0.1	-0.3	1.1	-0.0	0.3	-0.6	-0.1	-0.0	-0.0	0.1	1.1	1.2	-0.0	0.1	-0.3
Supplements: Glucosamine	0.1	0.2	0.4	-0.1	-0.3	-0.1	0.2	-0.4	-0.6	-0.4	-0.6	-0.5	0.3	-0.2	-0.3	0.2	-0.5	-0.4	-0.5	-0.6	-0.5	-0.5	-0.3	0.6	-0.7	-0.3	-0.6	-0.5
Waist circumference	0.1	0.4	1.8	-0.6	0.2	-0.4	-0.1	-0.9	-0.7	-0.7	-0.6	0.7	0.1	-0.0	-0.3	-0.6	-0.3	-1.3	-0.4	0.1	-0.7	-0.3	-0.2	0.6	-1.1	0.4	-0.8	-0.9
Qualifications: None of the above	0.1	0.1	1.3	0.3	-0.5	0.2	-0.7	-0.4	-0.1	0.1	-0.0	-0.1	-1.2	-0.2	0.0	-0.2	-0.0	-0.0	0.1	-0.2	0.2	0.2	0.3	0.0	-0.1	-0.1	-0.4	0.1
Father’s age at death	0.1	0.2	1.8	0.1	-0.0	0.4	0.5	0.1	0.2	0.3	0.4	-0.1	-0.1	0.1	0.2	0.2	0.2	0.1	-0.0	-0.0	0.3	0.1	0.4	-0.1	0.7	1.4	0.0	0.6
Frequency of tiredness / lethargy in last 2 weeks	0.1	0.1	0.5	0.2	-0.3	0.1	-0.5	0.4	-0.2	0.1	0.2	-0.5	0.7	-0.3	-0.1	0.4	-0.1	-0.4	-0.3	-0.3	0.2	-0.4	0.1	-0.2	0.2	-0.1	-0.4	-0.4
Happiness	0.1	0.2	0.4	0.1	0.5	0.5	0.5	0.4	0.5	0.4	0.4	0.4	0.4	0.5	0.5	0.3	0.5	0.2	0.2	0.5	0.4	0.6	0.5	-0.5	0.2	0.0	0.5	0.3
Asthma	0.1	0.2	0.6	-0.2	0.6	-0.2	0.7	-0.4	-0.3	-0.5	0.0	0.6	0.3	0.2	0.3	0.8	-0.1	0.1	0.1	0.2	-0.3	0.1	-0.3	0.2	-0.2	0.7	-0.7	-0.1
Medication: Lansoprazole	0.1	0.1	0.9	0.3	-0.1	-0.1	0.3	-0.1	0.4	-0.1	-0.3	-0.6	-0.0	0.1	-0.1	0.5	-0.2	-0.1	0.4	-0.2	0.1	-0.3	-0.2	-0.9	0.2	-0.4	-0.2	-0.9
Standing height	0.1	1.1	2.9	0.1	1.0	1.5	0.7	1.7	1.2	1.0	1.3	0.7	1.2	1.5	1.1	-1.1	1.2	0.5	1.3	1.2	0.7	0.8	0.9	-1.4	0.6	0.4	-0.7	-0.8
Tense / ‘highly strung’	0.1	0.2	0.6	0.7	0.3	0.6	0.7	-0.0	0.3	0.4	0.7	-0.1	0.1	0.6	0.4	0.3	0.3	0.5	0.6	0.1	0.3	0.6	0.2	-0.7	0.2	0.6	-0.1	0.3
Birth weight of first child	0.1	0.2	1.1	0.4	0.2	0.5	0.4	-0.1	0.4	0.5	0.5	0.3	0.1	0.2	0.4	-0.3	0.3	1.0	-0.2	0.2	0.5	0.1	0.0	0.8	-0.0	0.4	0.1	0.9
Birth weight	0.1	0.3	1.0	-0.5	-0.9	-0.3	-0.7	0.2	-0.2	0.1	-0.2	-0.8	-0.5	-0.6	-0.3	0.6	-0.3	-0.3	-0.2	-0.6	-0.0	-0.4	-0.5	0.2	1.0	-1.0	0.0	0.2
Wheeze or whistling in the chest in last year	0.1	0.2	0.9	-0.3	-0.2	-0.3	-0.5	-0.3	-0.7	-0.5	-0.6	0.2	0.0	-0.3	-0.3	-0.3	-0.4	-0.2	-0.4	-0.3	-0.4	-0.4	-0.3	0.9	-0.1	1.0	-0.8	-0.3
Heart disease (mother)	0.1	0.1	0.5	0.2	-0.6	0.1	-0.6	0.4	0.4	0.5	0.5	-0.5	-0.1	-0.3	-0.2	-0.4	0.0	0.2	-0.2	-0.3	-0.0	-0.0	0.7	0.1	0.3	0.1	0.1	-0.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.1	0.2	0.4	0.3	0.5	0.3	0.4	0.1	0.3	0.3	0.4	0.6	-0.1	0.3	0.3	0.4	0.4	0.6	-0.2	0.4	0.4	0.4	-0.0	0.2	0.4	0.5	0.6	0.4
Leg fat mass (right)	0.1	0.3	1.3	-0.5	-0.2	-0.3	-0.5	-0.9	-0.7	-0.5	-0.6	0.3	-0.0	-0.3	-0.4	-0.5	-0.4	-1.1	-0.5	-0.1	-0.5	-0.4	-0.4	1.0	-0.6	0.6	-1.0	-0.6
Comparative height size at age 10	0.1	0.7	2.7	-1.4	-0.0	-0.2	-0.2	-0.4	-0.5	-0.5	-0.3	-0.2	-0.3	-0.1	-0.1	-1.6	-0.3	-0.9	-0.1	-0.1	-0.4	-0.5	-0.9	-1.6	-0.7	-1.3	-1.6	-1.5
Had major operations	0.1	0.1	1.0	0.2	0.0	0.1	-0.2	0.5	0.2	0.1	0.1	0.3	0.5	0.1	0.0	-0.2	0.1	0.4	0.3	0.1	0.1	-0.0	0.4	1.0	0.6	0.5	0.1	-0.4
Ever had bowel cancer screening	0.1	0.1	0.4	0.2	-0.1	-0.3	0.2	-0.3	-0.3	-0.4	-0.6	-0.2	-0.3	-0.0	-0.2	0.2	-0.4	-0.1	-0.2	-0.3	-0.6	-0.2	-0.2	-0.1	-0.4	-0.3	-0.0	-0.5
Asthma (self-reported)	0.1	0.3	1.4	0.2	1.0	0.1	1.2	-0.2	-0.1	-0.3	0.3	1.0	0.5	0.6	0.6	1.0	0.2	0.4	0.4	0.6	-0.1	0.4	-0.1	0.3	0.1	0.7	-0.4	0.3
Medication: Aspirin	0.1	0.1	0.6	0.4	0.1	0.2	0.2	0.6	0.5	0.3	0.2	0.0	0.3	0.4	0.3	0.6	0.2	0.3	0.8	0.2	0.2	0.3	0.0	0.1	0.1	0.4	0.1	-0.4
Miserableness	0.1	0.2	2.9	-0.1	-0.1	0.2	-0.2	0.1	0.0	0.2	0.3	-0.7	0.1	0.0	0.0	-0.3	-0.0	-0.1	-0.0	-0.2	0.2	-0.1	0.1	-1.7	0.4	0.5	-0.2	-0.2
Ever taken oral contraceptive pill	0.1	0.1	1.0	0.2	0.0	0.1	-0.1	0.3	0.0	0.1	-0.1	0.4	0.2	0.1	-0.1	0.3	0.1	0.6	-0.1	0.2	-0.2	0.2	0.1	1.0	0.3	0.3	-0.0	0.1
Hearing aid user	0.1	0.1	0.6	0.2	-0.6	-0.2	-0.3	-0.5	-0.1	-0.1	-0.1	-0.8	-0.5	-0.6	-0.4	-0.3	-0.4	-0.3	-0.4	-0.5	-0.3	-0.4	-0.1	-0.3	0.2	-0.4	-0.1	0.2
Commuting to job workplace: Public transport	0.1	0.1	1.2	-0.1	0.0	-0.3	0.0	0.2	-0.1	-0.3	-0.2	0.3	-0.5	0.0	0.0	0.1	-0.1	-0.2	0.5	0.0	-0.3	0.1	-0.4	0.5	-1.1	-0.4	0.4	-0.2
Pain type(s) experienced in last month: Hip pain	0.1	0.1	0.8	0.3	0.1	-0.1	0.2	0.2	-0.2	-0.2	-0.2	0.2	0.4	0.0	0.0	0.9	-0.2	0.2	0.3	0.0	0.1	-0.1	-0.1	0.6	-0.1	0.0	0.0	0.4
Ever had prostate specific antigen (PSA) test	0.1	0.2	0.8	0.6	0.1	0.4	0.1	0.4	-0.2	0.3	0.3	0.3	0.1	0.2	0.3	-0.2	0.3	0.9	0.1	0.3	0.3	0.4	0.7	0.5	0.9	0.4	0.3	0.1
Ever depressed for a whole week	0.1	0.2	0.9	-0.4	-0.2	-0.2	-0.6	-0.2	-0.1	0.0	0.4	-0.2	0.0	-0.2	-0.2	0.6	0.0	-0.0	0.1	0.1	0.4	0.0	-0.3	-0.9	-0.5	-1.0	-0.4	-0.5
Leg fat mass (left)	0.1	0.3	1.2	-0.5	-0.2	-0.3	-0.4	-0.8	-0.7	-0.5	-0.6	0.4	0.0	-0.2	-0.4	-0.3	-0.3	-1.1	-0.5	-0.1	-0.4	-0.4	-0.4	1.1	-0.5	0.9	-1.0	-0.6
Reaction Time	0.0	0.1	0.5	0.2	-0.0	-0.1	-0.1	0.3	-0.2	0.2	0.0	0.1	0.3	-0.2	0.1	0.2	0.1	0.6	-0.1	-0.0	0.1	-0.1	0.7	0.4	0.4	-0.7	0.4	0.0
Triglycerides	0.0	0.1	0.4	-0.3	0.2	-0.3	0.3	0.0	-0.1	-0.3	-0.3	0.1	0.3	-0.1	-0.0	0.6	-0.1	-0.3	-0.2	0.1	-0.2	-0.0	-0.3	-0.3	-0.1	-0.5	0.0	-0.1
Trunk fat percentage	0.0	0.1	0.6	0.1	0.2	0.2	-0.1	0.1	0.2	0.1	0.1	0.7	0.3	0.3	0.2	-0.1	0.2	0.1	0.2	0.3	0.3	0.1	0.1	0.8	0.1	0.7	-0.4	-0.2
Trunk fat mass	0.0	0.2	1.0	-0.4	-0.1	-0.1	-0.4	-0.3	-0.3	-0.3	-0.3	0.4	0.1	0.0	-0.2	-0.5	-0.2	-0.6	-0.1	0.1	-0.2	-0.3	-0.3	0.6	-0.5	0.5	-1.0	-0.9
Headache pain in last month	0.0	0.1	0.4	0.4	0.4	0.1	0.4	0.6	-0.1	-0.1	0.1	0.1	0.6	0.4	0.3	0.3	-0.0	-0.1	0.4	0.1	0.2	0.1	-0.0	-0.3	-0.1	0.1	0.2	-0.1
Body fat percentage	0.0	0.2	1.6	0.3	0.2	0.3	-0.1	0.1	0.2	0.2	0.2	0.8	0.4	0.3	0.3	0.1	0.3	0.1	0.3	0.4	0.3	0.2	0.2	1.3	0.3	0.8	-0.3	0.1
Mean time to correctly identify matches	0.0	0.0	0.3	0.2	-0.0	-0.2	-0.0	-0.1	-0.2	0.2	-0.0	-0.0	-0.0	-0.3	0.0	0.4	-0.0	0.4	-0.2	-0.1	0.3	-0.1	0.5	0.1	0.4	0.1	0.3	-0.0
Whole body fat mass	0.0	0.2	0.8	-0.4	-0.2	-0.1	-0.4	-0.4	-0.3	-0.2	-0.3	0.3	0.2	-0.0	-0.2	-0.4	-0.2	-0.7	-0.2	0.0	-0.2	-0.3	-0.3	0.6	-0.5	0.4	-0.9	-0.8
Mood swings	0.0	0.1	0.9	-0.0	-0.1	-0.0	0.0	0.0	-0.2	-0.2	-0.1	-0.2	0.4	-0.0	0.0	0.1	-0.1	-0.1	-0.1	-0.0	-0.3	-0.1	-0.1	-0.6	0.2	-0.9	-0.4	-0.0

Hub : Genes

NELFCD

Models

Trait associations