Best TWAS P=5.71e-08 · Best GWAS P=7.97e-08 conditioned to 0.000145
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Hypothalamus | SPATC1L | 0.26 | 0.12 | lasso | 2 | 0.16 | 1.3e-04 | 5.0 | -5.2 | 2.3e-07 | -0.56 | 0.04 | 0.79 | FALSE |
| 2 | The Cancer Genome Atlas | Brain Lower Grade Glioma | C21orf56 | 0.18 | 0.14 | enet | 17 | 0.16 | 4.3e-18 | 5.1 | -5.4 | 6.2e-08 | -0.28 | 0.01 | 0.99 | FALSE |
| 3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | FTCD | 0.10 | 0.06 | lasso | 4 | 0.06 | 2.4e-07 | 5.1 | -5.4 | 5.7e-08 | -0.33 | 0.01 | 0.98 | TRUE |