Best TWAS P=1.02e-11 · Best GWAS P=7.13e-10 conditioned to 0.471
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Visceral Omentum | PRKD3 | 0.17 | 0.00 | enet | 18 | 0.01 | 1.1e-01 | 6.1 | 5.2 | 2.5e-07 | 0.58 | 0.01 | 0.92 | FALSE |
| 2 | GTEx | Artery Tibial | PRKD3 | 0.18 | 0.03 | enet | 26 | 0.11 | 1.0e-08 | 3.1 | 5.5 | 4.0e-08 | 0.56 | 0.03 | 0.95 | FALSE |
| 3 | GTEx | Nerve Tibial | PRKD3 | 0.25 | 0.08 | lasso | 6 | 0.22 | 2.8e-15 | 2.1 | 5.8 | 6.2e-09 | 0.45 | 0.65 | 0.35 | FALSE |
| 4 | The Cancer Genome Atlas | Prostate Adenocarcinoma | PRKD3 | 0.07 | 0.00 | blup | 74 | 0.01 | 1.8e-02 | 6.0 | -6.8 | 1.0e-11 | -0.85 | 0.01 | 0.72 | TRUE |