TWAS hub - PRKD3

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0810	0.0270	2.6e-04	0.041	0.029	0.029	0.033	0.036	8.2e-06	1.4e-04	1.4e-04	6.6e-05	3.0e-05
2	GTEx	Adipose Visceral Omentum	0.1690	0.0660	5.5e-03	0.002	NA	0.009	NA	0.003	2.5e-01	NA	1.1e-01	NA	2.0e-01
3	GTEx	Artery Aorta	0.2950	0.0640	6.9e-07	0.166	NA	0.160	NA	0.190	1.8e-09	NA	3.9e-09	NA	1.0e-10
4	GTEx	Artery Coronary	0.2830	0.0880	2.0e-03	0.222	NA	0.166	NA	0.202	4.9e-08	NA	3.0e-06	NA	2.3e-07
5	GTEx	Artery Tibial	0.1772	0.0471	2.3e-05	0.027	NA	0.107	NA	0.060	3.3e-03	NA	1.0e-08	NA	1.7e-05
6	GTEx	Lung	0.1470	0.0401	4.2e-05	0.045	NA	0.101	NA	0.080	2.2e-04	NA	3.8e-08	NA	1.0e-06
7	GTEx	Nerve Tibial	0.2452	0.0561	8.9e-07	0.078	NA	0.174	NA	0.216	3.4e-06	NA	2.3e-12	NA	2.8e-15
8	GTEx	Prostate	0.2960	0.1030	5.5e-03	-0.001	NA	0.042	NA	0.042	3.3e-01	NA	3.2e-02	NA	3.2e-02
9	GTEx	Skin Not Sun Exposed Suprapubic	0.2040	0.0570	1.3e-04	0.112	NA	0.082	NA	0.109	1.0e-06	NA	2.9e-05	NA	1.5e-06
10	GTEx	Skin Sun Exposed Lower leg	0.1190	0.0370	4.1e-04	0.041	NA	0.032	NA	0.039	2.6e-04	NA	1.1e-03	NA	3.4e-04
11	GTEx	Spleen	0.3190	0.1020	4.0e-03	0.288	NA	0.342	NA	0.350	4.3e-08	NA	1.3e-09	NA	7.7e-10
12	GTEx	Thyroid	0.2900	0.0500	1.9e-12	0.176	NA	0.234	NA	0.250	1.9e-13	NA	6.5e-18	NA	3.6e-19
13	METSIM	Adipose	0.0931	0.0270	1.8e-06	0.049	0.048	0.028	0.048	0.036	6.0e-08	8.6e-08	4.3e-05	9.9e-08	3.1e-06
14	NTR	Blood	0.0385	0.0108	1.1e-06	0.025	0.017	0.017	0.018	0.023	1.3e-08	2.9e-06	2.3e-06	9.4e-07	3.9e-08
15	ROSMAP	Brain Pre-frontal Cortex	0.0911	0.0249	7.9e-07	0.080	0.046	0.063	0.055	0.066	1.7e-10	1.4e-06	1.5e-08	1.3e-07	6.4e-09
16	TCGA	Kidney Renal Clear Cell Carcinoma	0.0542	0.0264	1.3e-05	0.017	0.045	0.039	NA	0.050	4.7e-03	7.8e-06	2.7e-05	NA	2.3e-06
17	TCGA	Prostate Adenocarcinoma	0.0712	0.0472	4.2e-03	0.001	0.012	-0.002	NA	0.002	2.6e-01	1.8e-02	5.8e-01	NA	1.8e-01

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17
Alzheimer’s Disease (including proxy)	4.8	6.9	20.5	-4.5	1.1	3.1	3.7	1.0	1.6	1.5	0.6	3.4	2.3	2.9	1.0	-0.9	-4.0	-4.2	-1.7	1.8
Hypertension (Self-reported)	4.4	12.2	39.3	6.3	-2.6	-4.3	-3.4	-1.4	-2.5	-2.8	0.2	-4.0	-2.1	-3.9	-2.0	0.0	4.9	5.9	3.8	0.4
Systolic Blood Pressure	4.3	21.5	58.7	7.7	-5.0	-5.0	-3.6	-4.3	-3.7	-4.4	-0.3	-4.0	-2.7	-3.9	-2.9	0.5	5.6	7.5	6.8	3.2
High blood pressure	4.3	12.0	38.1	6.2	-2.4	-4.4	-3.6	-1.2	-2.5	-2.8	0.0	-4.2	-2.4	-4.0	-2.0	0.1	4.8	5.8	3.5	-0.0
Vascular/heart problems diagnosed by doctor	4.1	11.1	34.4	-5.9	2.2	4.5	3.4	1.4	2.8	2.7	0.4	4.0	2.3	3.8	2.1	0.1	-4.4	-5.4	-3.3	-0.3
Prospective memory result	4.0	4.9	10.7	1.8	0.6	2.4	1.3	1.7	3.2	2.2	2.6	1.6	2.4	2.1	3.3	2.9	2.7	2.3	1.3	-0.8
Ulcerative Colitis	3.8	5.5	14.4	1.4	1.9	2.0	1.0	2.8	3.5	3.2	2.7	1.5	2.1	1.7	3.1	2.4	1.2	2.0	-1.1	-3.8
Medication: Atenolol	3.7	4.6	17.4	4.2	-1.3	-2.3	-2.2	-1.8	-1.3	-1.1	-0.6	-1.7	-1.2	-1.7	-0.9	0.2	3.8	3.6	2.6	-0.4
Systolic blood pressure, automated reading	3.6	10.3	20.2	4.1	-3.4	-3.9	-2.0	-3.3	-3.4	-3.8	-1.2	-3.4	-2.3	-3.4	-3.1	-1.4	3.0	4.0	4.5	2.3
Bipolar Disorder (2011)	3.5	3.4	8.0	0.9	1.9	1.6	1.1	2.8	2.8	2.8	1.2	1.2	1.8	1.3	2.5	1.8	0.8	1.1	-0.1	-2.6
Medication: Blood pressure	3.4	6.5	22.9	4.8	-2.1	-2.8	-2.1	-1.3	-1.3	-1.6	0.9	-2.5	-1.0	-2.2	-1.0	0.9	4.2	4.8	3.2	-0.5
Birth weight	3.2	7.0	26.7	-3.0	3.1	-0.5	-0.5	1.9	-0.4	0.6	-2.2	-1.4	-1.2	-1.2	-0.6	-5.1	-3.8	-3.0	-5.2	-3.3
Medication for cholesterol	3.2	4.9	21.3	-4.3	1.3	1.2	0.6	0.4	-0.0	0.1	-2.0	0.7	-0.3	0.5	-0.4	-2.2	-4.3	-4.6	-3.2	0.8
Bipolar Disorder or Schizophrenia	3.1	7.6	17.6	1.6	2.4	2.2	2.3	2.7	3.2	4.2	2.6	2.4	3.6	2.6	3.9	2.9	1.9	1.6	-0.4	-3.5
Ulcerative Colitis (UC)	3.1	5.8	12.8	1.2	2.0	2.3	1.3	3.3	3.6	3.3	3.2	1.8	2.4	2.0	3.2	2.2	0.8	1.9	-1.0	-3.0
Illness, injury, bereavement, stress in last 2 years	3.1	3.8	7.3	1.3	-2.7	-2.6	-2.0	-2.1	-2.6	-2.6	-1.3	-2.2	-1.9	-2.3	-2.1	0.5	0.6	1.2	1.7	1.3
Serious illness, injury or assault to yourself	3.0	3.7	7.0	-1.3	2.3	2.5	2.0	2.1	2.7	2.6	1.1	2.2	2.1	2.3	2.2	0.7	-0.8	-0.9	-1.5	-1.1
Schizophrenia (2014)	2.9	6.4	15.0	1.8	3.1	1.7	1.5	2.4	3.0	3.5	2.5	1.4	2.8	1.7	3.6	2.3	2.5	1.8	-0.9	-3.9
Medication for hormone replacement therapy	2.8	3.1	7.5	2.3	0.0	1.0	1.4	1.6	1.9	1.6	1.8	1.4	1.8	1.4	1.9	1.8	2.7	2.6	1.9	-0.9
Length of working week for main job	2.8	3.1	7.1	0.1	0.4	2.1	2.1	1.9	2.1	2.2	1.6	2.2	2.3	2.4	2.1	2.7	0.6	0.4	0.4	-0.5
Heart attack/myocardial infarction (self-reported)	2.7	3.4	10.5	3.2	-0.0	-2.5	-2.0	-0.6	-1.6	-1.2	-0.2	-2.0	-1.4	-2.1	-1.1	0.4	2.6	3.1	2.0	-0.1
Schizophrenia (2018)	2.6	5.4	15.2	1.4	2.7	1.5	1.9	2.1	2.4	3.7	2.0	1.9	2.9	2.0	3.1	1.6	1.6	1.4	-0.9	-3.9
Heart attack	2.6	3.3	10.2	3.2	0.2	-2.5	-1.9	-0.4	-1.5	-1.1	-0.4	-2.0	-1.3	-2.1	-1.0	0.3	2.7	3.0	2.0	-0.2
Number of live births	2.6	3.7	9.7	1.1	0.1	-2.3	-2.7	-1.6	-2.7	-2.3	-0.3	-3.1	-2.7	-3.0	-2.4	-0.6	0.5	0.8	0.5	-0.5
Alzheimer’s Disease (in mother)	2.5	2.9	12.8	-3.6	0.6	1.1	1.9	-0.2	0.3	0.1	-1.2	1.1	0.6	0.8	-0.1	-1.3	-3.2	-3.5	-1.7	1.2
Other serious medical condition/disability diagnosed by doctor	2.5	3.3	7.0	-0.5	1.6	2.5	1.9	1.4	2.6	2.5	1.9	2.3	2.3	2.3	2.6	0.5	0.4	-0.3	-0.6	-0.5
Hayfever/allergic rhinitis (self-reported)	2.5	3.3	7.2	0.8	-1.1	-2.4	-2.3	-1.5	-1.8	-2.5	-1.7	-2.7	-2.4	-2.5	-2.3	-1.6	0.2	0.3	0.6	1.0
Family relationship satisfaction	2.4	2.9	6.6	0.1	0.3	2.4	2.1	1.1	2.6	1.4	2.0	2.2	2.3	2.2	2.2	1.6	0.9	0.7	1.4	0.6
Ever had stillbirth, spontaneous miscarriage or termination	2.4	2.6	4.9	2.0	-1.3	-2.2	-1.9	-1.4	-1.8	-1.6	-0.9	-1.3	-1.7	-1.4	-1.5	0.1	1.9	1.7	2.1	1.0
Hypothyroidism/myxoedema (self-reported)	2.3	4.5	10.6	-2.5	2.0	2.0	2.0	2.4	2.0	2.8	1.2	1.8	1.6	1.6	1.6	-1.8	-2.3	-2.2	-3.2	-1.9
Age at last live birth	2.3	3.3	9.6	2.6	-1.3	-1.4	-3.1	-1.3	-1.0	-1.8	0.0	-2.5	-1.9	-2.3	-0.6	1.2	2.5	2.5	1.1	0.1
Fasting Glucose	2.2	2.6	8.7	1.8	-0.7	-2.2	-1.2	-1.0	-1.1	-1.7	-0.1	-2.0	-0.9	-1.9	-1.0	1.0	1.9	1.3	2.2	3.0
Hearing difficulty/problems: Yes	2.2	3.4	6.8	-1.6	0.1	-1.7	-2.3	-1.2	-2.0	-2.1	-2.3	-1.7	-2.6	-1.9	-2.3	-1.9	-1.8	-2.1	-1.1	0.8
Mouth/teeth dental problems: Dentures	2.2	3.7	9.2	0.1	1.2	-2.3	-3.0	0.2	-2.0	-1.3	-2.6	-2.6	-2.8	-2.6	-2.1	-1.5	-0.3	-0.4	-1.7	-2.0
Seen doctor (GP) for nerves, anxiety, tension or depression	2.2	3.3	9.4	-2.7	2.5	1.9	1.3	1.2	1.3	1.7	0.7	1.5	0.8	1.5	1.0	-0.9	-3.1	-2.5	-2.8	-0.8
Irritable Bowel Disease (IBD)	2.1	4.9	11.0	1.3	2.1	2.2	1.0	3.3	3.3	2.8	3.3	1.4	2.2	1.7	3.1	1.2	1.4	2.0	-0.5	-2.2
Ovarian Cancer	2.1	2.8	5.3	-1.8	1.3	-1.4	-1.0	-1.2	-2.2	-1.3	-2.1	-1.4	-1.7	-1.4	-2.1	-1.9	-2.2	-2.3	-1.9	-0.3
Medication: Amlodipine	2.1	2.9	9.9	3.1	-0.7	-1.4	-1.7	-1.0	-1.0	-1.4	1.2	-1.5	-1.0	-1.2	-0.8	0.8	2.5	3.0	2.7	0.9
Commuting to job workplace: Walk	2.1	2.3	6.8	0.4	-1.0	-1.8	-2.1	-1.8	-1.7	-1.9	-2.6	-1.8	-2.0	-1.8	-1.6	-0.4	-0.3	-0.0	0.3	0.7
Falls in the last year	2.0	2.7	5.9	0.5	-0.7	-2.1	-1.7	-2.2	-2.4	-2.1	-1.9	-2.1	-1.9	-2.1	-1.8	0.4	0.6	0.1	0.9	1.7
Medication: Bendroflumethiazide	2.0	3.0	14.8	3.9	-0.1	-1.4	-1.0	0.6	-0.1	-0.2	0.9	-1.1	-0.2	-1.0	0.2	1.2	3.2	3.6	2.2	-0.7
Diastolic blood pressure, automated reading	2.0	6.2	11.3	2.9	-3.4	-3.3	-1.8	-2.2	-3.2	-2.9	-1.0	-2.9	-2.0	-3.0	-2.7	-1.2	1.3	2.4	2.8	1.3
Unable to work because of sickness or disability	2.0	2.6	5.9	-0.4	2.1	2.2	1.8	1.5	2.2	2.0	1.9	1.5	2.1	1.5	2.4	1.0	0.3	-0.1	-0.9	-0.4
Alzheimer’s Disease (in father)	1.9	2.1	4.8	-2.2	0.7	1.6	1.9	1.2	1.2	0.9	1.0	1.8	1.5	1.5	0.8	-0.5	-2.1	-1.9	-1.1	1.1
Hearing difficulty/problems with background noise	1.9	3.0	8.9	-1.3	0.3	-1.2	-2.2	-0.8	-1.5	-2.3	-3.0	-1.8	-2.5	-1.9	-2.0	-1.5	-1.6	-1.6	-0.8	1.2
Lung cancer (father)	1.9	2.3	8.6	-2.9	1.1	0.8	1.0	0.8	-0.1	0.6	0.3	0.9	0.2	0.7	0.1	-1.2	-2.4	-2.9	-2.7	-1.1
Medication for cholesterol, blood pressure or diabetes	1.9	3.2	15.4	-3.9	0.6	1.1	1.1	-0.7	-0.1	-0.3	-0.6	0.9	-0.1	0.9	-0.5	-1.5	-3.5	-3.9	-1.7	1.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.9	2.3	5.4	-1.2	-0.1	-1.6	-1.0	-0.9	-2.1	-1.9	-2.3	-1.0	-1.6	-1.3	-2.1	-0.1	-1.8	-1.7	-0.7	1.7
Seen a psychiatrist for nerves, anxiety, tension or depression	1.8	2.4	5.0	-1.2	0.7	1.9	2.1	2.0	2.0	1.3	1.0	2.2	2.1	2.1	1.7	1.1	-1.0	-0.8	0.0	0.5
Osteoarthritis (self-reported)	1.8	2.4	8.5	-2.5	1.3	-0.5	-0.2	0.8	-0.8	-1.0	-2.3	-0.6	-1.0	-0.8	-1.4	-2.0	-2.5	-2.9	-1.3	0.3
Ever taken oral contraceptive pill	1.8	2.0	5.1	-1.5	2.0	0.9	1.1	2.3	1.2	1.6	0.8	1.0	0.8	0.9	0.8	-1.5	-1.7	-1.2	-2.1	-1.4
Bipolar Disorder (2018)	1.7	2.8	7.2	0.8	1.0	1.7	1.4	1.6	2.3	2.1	1.6	1.6	2.1	1.7	2.4	2.7	1.1	0.9	0.5	-0.7
Fed-up feelings	1.7	3.0	7.2	-0.1	0.5	2.0	2.5	1.1	1.8	1.7	2.7	2.5	2.4	2.5	2.1	1.2	0.2	0.3	1.0	1.1
Past tobacco smoking	1.7	3.2	6.1	-0.9	-2.0	-1.6	-1.8	-2.5	-2.2	-2.1	-1.2	-2.0	-2.4	-2.0	-2.4	-1.1	-1.4	-1.1	-0.5	1.3
Long-standing illness, disability or infirmity	1.7	2.7	5.6	-0.9	1.2	2.3	1.7	2.4	2.3	2.2	1.9	1.8	1.7	1.9	1.9	0.3	-0.5	-0.5	-1.0	-0.5
Basal cell carcinoma (self-reported)	1.7	2.0	6.2	-2.3	1.3	1.5	0.8	0.6	0.6	0.9	-0.0	1.2	0.6	1.1	0.8	-2.5	-1.8	-2.1	-2.2	0.0
Heel T-Score	1.6	12.8	46.2	0.4	5.2	2.8	2.3	5.5	3.9	5.8	2.0	2.7	3.1	2.7	3.9	0.7	-0.2	0.4	-2.8	-6.8
Age at first live birth	1.6	2.8	6.5	2.4	-1.4	-1.2	-2.5	-1.9	-0.9	-1.8	-0.3	-1.9	-1.4	-1.7	-0.4	1.5	2.2	2.3	1.5	1.1
Eye problems/disorders: None of the above	1.6	1.9	4.5	0.8	0.7	1.7	1.3	-0.4	1.7	1.1	1.4	1.4	1.7	1.6	2.1	1.7	1.3	1.0	1.4	0.9
Smoking status: Previous	1.6	2.3	4.8	0.8	1.6	1.6	1.5	1.9	1.9	1.7	1.2	1.8	2.2	1.8	2.1	1.0	1.3	1.0	0.5	-0.8
Irritability	1.6	2.7	5.5	1.6	-0.2	-2.3	-1.7	-1.3	-2.3	-2.2	-1.4	-2.2	-1.7	-1.9	-1.7	-1.0	1.0	1.1	1.6	1.1
Tinnitus: Yes, but not now, but have in the past	1.5	1.6	4.3	-0.9	1.9	1.5	1.0	2.1	1.9	1.4	0.8	0.7	1.1	0.9	1.6	1.1	-0.8	-0.5	-1.3	-0.3
Chronic bronchitis/emphysema (father)	1.5	1.8	5.1	0.1	-0.6	-1.8	-1.7	-0.4	-1.3	-2.1	-0.1	-2.2	-2.1	-2.2	-1.8	-0.3	0.1	-0.3	-0.0	0.8
Frequency of tiredness / lethargy in last 2 weeks	1.5	2.4	4.2	-2.1	2.0	1.9	2.0	1.3	1.6	1.2	1.7	1.5	1.5	1.6	1.5	-0.9	-1.5	-1.6	-1.2	1.1
Medication: Lansoprazole	1.5	1.7	5.2	-0.9	2.3	1.3	1.4	2.3	1.1	1.6	1.1	1.5	1.2	1.4	1.1	0.3	-0.9	-0.4	-1.1	-0.5
Illnesses of mother	1.5	1.8	3.5	-1.6	0.7	-1.1	-0.7	-1.6	-1.8	-1.2	-1.1	-0.9	-1.4	-1.0	-1.8	-1.1	-1.9	-1.9	-1.5	-0.2
Medication: Blood pressure	1.5	2.6	12.9	3.6	-0.6	-1.4	-1.1	0.8	-0.3	0.1	0.4	-1.2	-0.2	-1.2	0.1	0.6	2.9	3.4	1.3	-1.4
Number of full sisters	1.5	1.8	5.6	-2.1	0.9	1.3	1.7	1.3	0.6	1.0	0.6	1.3	0.8	1.4	0.4	-0.6	-2.4	-2.0	-1.7	-0.7
Ever had bowel cancer screening	1.5	1.8	5.4	-1.9	2.1	-0.0	-0.2	1.9	0.1	0.1	-0.4	-0.5	-0.7	-0.5	-0.5	-2.0	-1.9	-1.8	-2.3	-0.8
Risk taking	1.5	2.1	8.2	1.4	0.4	1.2	1.0	1.1	1.6	1.3	1.9	1.5	1.4	1.6	1.6	2.9	1.3	1.4	1.3	-0.1
Type 2 Diabetes (T2D) (2012)	1.4	1.6	2.7	-1.4	1.7	1.4	1.3	1.0	0.8	0.7	1.1	1.5	1.0	1.2	1.0	-1.6	-1.3	-1.2	-1.4	-1.3
Cardiovascular Disease	1.4	4.7	15.5	3.9	-1.2	-2.5	-1.7	-0.8	-1.7	-2.2	0.4	-2.3	-1.2	-2.2	-1.4	-0.3	2.7	3.9	2.7	1.3
Mouth/teeth dental problems	1.4	2.2	6.6	0.6	-1.4	1.2	1.9	-0.2	1.2	0.8	2.6	1.6	2.2	1.7	1.9	0.4	1.2	1.0	1.5	1.5
Medication: Cholesterol lowering	1.4	2.2	8.6	2.5	-0.2	0.3	0.1	1.2	1.0	1.0	1.3	0.6	1.0	0.7	1.4	2.1	2.7	2.9	1.4	-0.2
Illnesses of father: Heart disease	1.4	1.9	4.9	1.0	0.8	1.3	1.3	0.8	1.3	2.1	0.1	1.5	1.5	1.7	1.5	1.7	1.1	1.5	0.5	-2.2
Forced expiratory volume in 1-second (FEV1), predicted	1.4	2.9	8.6	-1.1	1.8	2.4	1.8	1.5	1.7	2.1	2.9	2.0	1.9	1.9	2.0	-0.3	-0.9	-0.6	-1.1	-0.5
Breast cancer (self-reported)	1.4	1.7	4.0	0.1	-0.0	1.7	1.7	0.2	1.4	1.3	1.7	1.9	2.0	1.9	1.9	-0.3	1.0	0.3	0.7	-0.5
Blood Red Count	1.3	12.3	25.7	-1.1	3.6	4.0	3.9	3.3	4.6	4.6	4.4	3.7	4.7	3.9	5.1	-0.1	-0.2	-0.4	-2.6	-2.6
Hypothyroidism (self reported)	1.3	3.0	7.8	-2.0	1.9	1.4	1.2	2.8	1.5	2.2	0.5	1.2	0.9	1.1	1.0	-1.2	-2.2	-1.8	-2.6	-2.0
High blood pressure (mother)	1.3	1.8	8.1	2.6	-0.7	-0.5	-1.4	1.3	0.5	0.0	1.1	-0.8	-0.4	-0.6	0.4	0.1	2.4	2.8	1.4	-0.7
Nervous feelings	1.3	2.4	7.3	-1.3	2.6	-0.9	-1.1	1.3	-0.8	0.1	-0.6	-1.4	-1.6	-1.3	-1.0	-1.9	-2.1	-1.4	-2.7	-1.8
Heel bone mineral density (BMD) T-score, automated (right)	1.3	3.0	9.7	-0.3	3.1	1.5	1.3	2.5	1.5	2.7	1.8	1.5	1.4	1.2	1.4	-0.4	-1.3	-0.4	-1.3	-2.5
Financial difficulties in last 2 years	1.3	1.7	3.9	-1.2	2.0	1.5	1.3	1.4	1.5	1.4	1.7	1.1	0.9	1.1	1.1	-1.5	-1.0	-0.9	-1.5	-0.6
Average weekly red wine intake	1.3	2.0	4.3	0.1	-1.7	-1.0	-1.5	-0.5	-1.7	-1.9	-2.1	-1.5	-1.9	-1.6	-1.8	-1.0	-0.6	0.1	0.8	1.6
Friendships satisfaction	1.3	1.6	2.7	-1.0	1.5	1.6	1.6	1.5	1.5	1.1	1.6	1.3	1.5	1.3	1.4	-1.2	-0.8	-0.6	-0.6	-0.3
Age started oral contraceptive pill	1.3	1.7	6.0	0.4	-0.9	-1.7	-1.6	-0.9	-1.4	-1.4	-2.4	-1.5	-1.6	-1.7	-1.4	-1.1	-0.4	0.2	-0.2	-0.4
Eye problems/disorders: Diabetes related eye disease	1.2	1.3	4.8	-1.8	-1.2	0.2	1.3	-0.9	-0.5	-0.7	-0.2	0.8	0.3	0.6	-0.9	-1.5	-1.9	-1.5	-0.0	2.2
Pain all over the body in last month	1.2	1.2	3.8	0.2	1.6	0.8	0.1	1.9	1.4	1.6	1.2	0.0	0.6	0.2	1.3	-0.5	0.3	0.4	-1.3	-1.9
Wheeze or whistling in the chest in last year	1.2	2.2	5.6	-1.4	1.7	1.9	0.4	2.3	1.6	1.6	1.4	1.1	0.8	1.2	1.4	-0.4	-1.1	-1.2	-2.4	-1.5
Overall health rating	1.2	2.5	7.4	-0.6	2.2	1.7	1.5	2.7	1.7	2.3	1.6	1.4	1.5	1.6	1.9	-0.4	-0.2	-0.3	-1.4	-1.5
Chest pain or discomfort	1.2	1.7	4.8	-1.5	0.8	1.7	1.2	0.7	0.9	1.3	1.6	1.2	1.1	1.2	1.3	1.3	-1.2	-1.2	-2.2	-0.8
Blood White Count	1.1	8.0	25.6	1.6	2.6	2.2	1.7	5.1	3.3	4.1	2.4	2.1	2.7	2.3	3.2	2.8	1.4	1.9	-1.1	-4.2
Waist Hip Ratio (WHR)	1.1	5.0	12.8	-0.8	-0.3	2.8	3.6	1.6	2.1	2.1	1.4	3.5	3.2	3.5	2.4	2.9	-1.0	-0.5	0.8	0.7
Angina	1.1	1.5	5.2	1.4	0.2	-2.3	-1.8	-0.2	-1.3	-0.5	-1.7	-1.6	-1.4	-1.6	-1.0	-0.3	0.5	0.9	-0.7	-0.9
Impedance of leg (right)	1.1	5.3	21.3	4.1	-0.6	0.0	0.2	1.0	2.0	1.0	0.9	0.6	1.2	0.6	1.8	4.6	3.4	4.2	3.2	0.2
Medication: Levothyroxine sodium	1.1	1.8	4.7	-1.1	0.6	1.5	1.4	1.7	1.6	2.2	0.9	1.4	1.2	1.4	1.1	0.2	-1.2	-0.8	-1.7	-1.5
Impedance of leg (left)	1.1	5.6	22.8	4.2	-1.0	-0.2	0.3	0.5	1.8	0.6	0.3	0.5	1.2	0.5	1.6	4.8	3.5	4.2	3.6	1.1
Reason for reducing amount of alcohol drunk: Health precaution	1.1	1.2	3.6	1.8	-0.1	-0.8	0.2	-1.2	-0.0	-0.9	0.3	-0.5	0.5	-0.4	-0.1	0.9	1.8	1.9	1.9	1.8
Illnesses of father: High blood pressure	1.1	1.4	4.9	2.1	-0.1	0.7	0.6	-0.3	0.6	0.9	1.0	0.8	1.2	0.8	1.2	0.8	1.8	2.2	1.8	-0.4
Ever smoked	1.1	2.0	4.8	0.6	0.8	1.3	1.8	1.2	1.6	1.5	1.6	2.0	2.2	2.0	1.8	1.1	0.8	0.9	0.9	-0.4
Body Mass Index (BMI) (2010)	1.0	1.4	4.7	-1.5	1.1	1.1	0.8	0.3	0.5	1.1	0.9	0.6	0.4	0.8	0.5	-2.1	-1.4	-1.4	-2.2	-1.5
Rheumatoid Arthritis	1.0	1.3	5.5	-0.9	-0.9	-1.3	-0.6	-2.3	-1.6	-1.2	-0.4	-0.8	-1.1	-0.9	-1.5	-0.5	-0.7	-1.4	-0.8	0.8
Alcohol intake versus 10 years previously	1.0	1.5	5.5	-1.1	2.0	1.1	0.1	1.3	1.1	1.3	0.0	0.8	0.6	0.6	1.1	-0.7	-0.7	-1.0	-2.4	-1.9
Mouth/teeth dental problems: Bleeding gums	1.0	1.3	4.3	-2.1	1.4	1.0	0.7	-0.4	0.4	0.5	-1.3	0.7	-0.0	0.5	-0.1	-1.1	-2.0	-1.9	-1.6	-0.5
Worry too long after embarrassment	1.0	1.6	4.6	-2.0	0.9	0.5	-1.1	0.2	-0.5	-0.9	-1.2	-0.6	-1.4	-0.8	-0.8	-1.9	-2.0	-2.1	-1.7	0.5
Shortness of breath walking on level ground	1.0	1.2	4.8	1.8	0.3	-0.2	-0.6	1.3	0.2	0.4	1.0	-0.5	0.2	-0.3	0.7	1.9	2.2	1.7	1.0	-0.8
Migraine (self-reported)	1.0	1.2	5.6	0.3	1.1	0.4	-1.2	2.4	1.4	0.8	0.9	-0.5	-0.4	-0.6	0.9	0.3	0.3	0.1	-1.6	-2.2
Illnesses of father: None of the above (group 1)	1.0	1.2	4.7	-1.8	0.7	-0.2	-0.4	0.6	-0.6	0.0	-0.8	-0.1	-0.7	-0.2	-0.5	-1.5	-1.9	-2.0	-2.2	-0.4
Hearing aid user	1.0	1.1	4.5	-1.6	0.6	-0.2	-0.4	0.9	0.0	0.3	-1.2	-0.2	-0.8	-0.2	-0.5	-1.3	-1.6	-1.9	-2.1	-0.4
Commuting to job workplace: Cycle	1.0	1.3	4.6	-0.4	-0.7	-1.1	-1.1	-2.1	-1.5	-1.6	-1.1	-0.9	-1.4	-0.9	-1.5	-0.5	-0.3	-0.5	0.4	1.2
Impedance of whole body	1.0	4.9	21.9	4.7	-1.0	-1.4	-1.2	-0.2	0.6	-0.1	-0.1	-0.7	-0.1	-0.7	0.6	3.4	3.4	4.4	3.5	0.7
Schizophrenia vs Biploar Disorder	0.9	1.1	4.0	-0.9	1.9	-0.2	-0.8	-1.0	-0.4	-0.4	-0.8	-0.9	-0.8	-1.0	-0.2	-2.0	0.1	-1.0	-1.9	-1.2
Average weekly spirits intake	0.9	1.1	3.8	-0.2	0.8	1.0	0.2	1.9	1.0	1.7	0.5	1.0	0.7	0.9	1.2	0.7	-0.4	0.0	-1.5	-1.5
Severe depression (siblings)	0.9	1.0	2.3	-0.2	0.8	1.1	1.3	0.6	1.1	1.4	1.0	1.3	1.3	1.5	1.1	1.3	0.2	0.1	0.6	-0.5
Number of incorrect matches in round	0.9	1.5	5.5	1.9	0.4	0.5	-0.2	-0.3	0.8	0.5	2.0	0.3	0.6	0.4	1.1	1.8	2.3	1.9	1.4	-0.3
Allergy	0.9	2.0	7.7	1.2	-2.5	-0.6	-0.1	-1.5	-0.4	-1.2	-0.1	0.1	0.1	0.0	-0.2	1.7	1.9	1.2	2.8	2.5
Hair/balding pattern: Pattern 3	0.9	1.4	6.0	-0.1	-1.4	-1.0	-0.2	-2.5	-1.1	-1.8	-0.4	-0.5	-0.5	-0.7	-1.1	-1.0	-0.5	-0.3	1.1	2.4
Impedance of arm (left)	0.9	4.3	17.5	4.2	-0.6	-2.5	-2.6	-1.0	-0.8	-0.9	-0.9	-1.9	-1.5	-2.0	-0.6	1.5	2.5	3.7	2.6	0.3
Chronic bronchitis/emphysema (mother)	0.9	1.0	2.5	0.3	0.3	1.4	1.0	0.7	1.2	0.7	1.5	0.8	1.0	0.7	1.1	1.6	1.1	0.6	1.0	0.8
Angina (self-reported)	0.9	1.2	4.2	1.1	0.3	-2.0	-1.5	-0.2	-1.2	-0.5	-1.4	-1.4	-1.2	-1.5	-0.9	-0.5	0.4	0.5	-0.9	-0.8
Suffer from ‘nerves’	0.9	1.5	5.0	-1.1	2.2	0.7	1.0	1.6	0.7	1.2	0.8	0.7	0.6	0.6	0.6	-2.1	-1.6	-1.0	-1.4	-0.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.9	1.1	2.3	-0.0	1.1	1.1	1.5	1.4	1.2	1.3	1.5	1.1	1.2	1.1	1.1	0.7	-0.5	0.1	0.2	-0.4
Mineral and other dietary supplements	0.9	1.2	3.5	-0.1	-0.0	1.2	1.6	0.7	1.2	1.5	1.9	1.3	1.6	1.2	1.4	-0.0	0.4	-0.1	-0.3	-1.2
Supplements: Fish oil (including cod liver oil)	0.9	1.2	3.8	-0.0	0.0	-1.1	-1.6	-0.8	-1.0	-1.2	-1.9	-1.5	-1.7	-1.5	-1.4	-0.8	-0.7	-0.2	-0.4	0.1
Major Depression (MDD)	0.8	0.9	4.9	1.4	0.2	-0.4	-1.1	-1.4	0.1	-0.6	0.3	-1.1	-0.6	-1.0	0.1	0.1	2.2	1.2	0.8	0.7
Prostate Cancer	0.8	1.1	4.0	-1.9	1.1	0.0	0.1	-1.3	-0.5	-0.1	-0.3	0.0	-0.2	-0.1	-0.4	-1.9	-1.1	-2.0	-1.8	-0.2
Chronotype (morning person)	0.8	1.8	4.9	0.0	0.3	-1.3	-2.2	0.3	-1.1	-1.0	-1.2	-2.0	-2.1	-2.0	-1.6	-1.2	-1.0	-0.2	-1.5	-1.0
Frequency of depressed mood in last 2 weeks	0.8	1.1	4.1	-1.5	1.2	0.6	1.4	-0.2	0.2	0.6	0.3	1.1	0.7	1.1	0.1	-2.0	-1.7	-1.5	-0.7	0.3
Supplements: Zinc	0.8	0.8	3.1	-0.2	0.5	-0.9	-1.2	-0.8	-1.1	-0.4	-1.5	-1.0	-1.1	-0.9	-0.7	-1.8	-0.2	-0.2	-0.7	-0.6
Hand grip strength (right)	0.8	2.0	4.7	-1.4	-0.3	1.8	2.2	0.4	1.3	1.1	1.7	2.1	1.8	2.0	1.2	-0.4	-2.0	-1.1	-0.8	0.5
Illnesses of siblings	0.8	1.1	3.8	-1.2	1.6	0.8	0.6	1.9	0.8	0.8	0.9	0.5	0.5	0.6	0.7	0.1	-1.3	-1.1	-1.9	-0.8
Impedance of arm (right)	0.8	3.7	16.6	4.1	-0.6	-2.1	-2.5	-0.2	-0.4	-0.7	-0.6	-1.6	-1.3	-1.6	-0.4	1.7	2.3	3.6	2.6	0.3
Time employed in main current job	0.8	0.9	3.9	0.6	-1.9	-0.2	1.0	-0.4	-0.2	-0.4	-0.5	0.5	0.9	0.3	0.1	1.6	0.9	0.5	2.0	1.1
Pulse wave reflection index	0.8	0.9	2.7	0.3	0.2	-1.0	-1.6	-0.5	-0.8	-0.8	-1.4	-1.5	-1.6	-1.5	-1.1	-0.3	0.1	-0.3	-0.4	-0.2
Neck or shoulder pain in last month	0.8	1.1	4.3	-0.7	1.7	-0.8	-0.9	0.3	-0.6	-0.9	-0.5	-1.4	-1.0	-1.6	-0.8	-2.1	-0.2	-1.0	-1.0	-0.8
Medication: Ibuprofen	0.8	0.9	3.2	-1.8	-0.8	-0.1	1.1	0.5	-0.5	-0.1	-0.2	0.6	0.1	0.7	-0.7	-1.1	-1.7	-1.8	-0.2	1.1
Medication: Seretide 50 evohaler	0.8	1.0	2.1	-0.6	1.0	1.2	1.2	0.6	1.4	1.5	0.4	1.0	1.1	1.1	1.0	-0.1	-0.6	-0.5	-1.1	-1.2
Leg pain on walking	0.8	1.0	3.4	1.7	0.5	-0.9	-1.4	0.3	-0.2	0.4	-0.4	-1.1	-0.8	-0.9	-0.1	0.4	1.3	1.3	0.4	-1.9
Eye problems/disorders: Cataract	0.8	1.0	3.8	0.3	-0.4	-0.9	-1.5	1.1	-0.7	-0.5	-1.9	-1.1	-1.2	-1.1	-0.9	-1.0	-0.0	0.1	-0.6	-1.1
Mouth/teeth dental problems: Mouth ulcers	0.8	1.3	6.7	-0.2	-0.7	-1.0	-0.8	-1.1	-1.2	-1.6	-2.6	-1.0	-1.1	-1.0	-1.4	0.3	-0.2	-0.4	0.5	1.5
Medication: Lisinopril	0.8	1.0	3.2	1.2	-0.8	0.6	1.1	0.8	0.5	0.7	1.0	0.9	1.4	1.0	0.9	0.9	1.1	1.8	1.0	-0.1
Number of operations (self-reported)	0.8	1.1	5.9	-1.3	0.4	-0.5	-1.1	0.4	-0.5	-0.5	-2.4	-0.7	-1.2	-0.8	-0.8	-0.4	-1.0	-1.6	-1.4	0.2
Verbal and Numeric Reasoning (VNR)	0.7	1.7	7.5	-2.5	0.5	0.3	0.3	1.0	0.0	-0.1	-0.1	0.3	-0.4	-0.1	-0.6	-1.6	-2.7	-2.6	-2.0	-0.1
Breast Cancer	0.7	1.7	6.1	1.6	-0.9	-1.2	-0.4	-2.5	-1.2	-1.5	0.0	-1.1	-0.4	-0.9	-0.9	-0.0	1.1	1.4	2.4	1.4
HbA1C	0.7	0.8	3.1	0.6	-1.6	-0.9	0.1	-0.7	-1.4	-0.9	-0.1	-0.0	-0.0	0.1	-0.8	0.2	0.6	0.4	1.7	1.3
Blood Eosinophil Count	0.7	5.6	24.9	-0.3	2.6	0.9	0.6	4.6	2.4	3.7	0.1	0.9	1.3	1.1	2.1	-0.8	-1.0	-0.3	-3.4	-5.0
Smoking Status	0.7	1.7	3.3	-1.2	1.7	1.5	1.6	1.1	0.9	1.4	1.7	1.8	1.7	1.6	1.2	-0.3	-0.7	-1.2	-0.8	0.6
Number of treatments/medications taken	0.7	1.3	3.4	1.9	-0.9	-1.4	-1.6	-0.1	-1.0	-0.8	-0.5	-1.3	-1.1	-1.2	-0.8	0.4	1.8	1.7	0.9	0.0
Medication: Co-codamol	0.7	0.8	1.8	0.0	-1.0	-1.0	-1.3	-1.2	-1.0	-0.8	-0.5	-1.2	-1.1	-1.1	-0.7	-1.1	0.7	-0.2	0.0	0.3
Heel bone mineral density (BMD) T-score, automated (left)	0.7	1.6	5.5	-0.5	2.3	0.6	0.8	1.6	0.7	2.0	0.4	1.1	0.9	0.7	0.7	-0.9	-1.4	-0.7	-1.3	-2.4
Hayfever, allergic rhinitis or eczema	0.7	1.6	7.1	-1.1	1.4	0.7	-0.1	1.6	0.7	1.1	-0.0	-0.2	-0.3	-0.1	0.4	-1.5	-1.2	-1.0	-2.7	-2.6
Frequency of tenseness / restlessness in last 2 weeks	0.7	1.1	5.1	-1.3	2.2	-0.1	-0.1	1.4	-0.0	0.1	-0.5	-0.5	-0.7	-0.4	-0.4	-0.8	-1.8	-1.3	-1.6	-0.7
Qualifications: None of the above	0.7	1.5	4.1	0.2	2.0	1.1	0.9	1.9	1.2	1.8	1.2	1.0	1.1	1.1	1.4	1.0	0.2	0.2	-0.6	-1.6
Father’s age at death	0.7	1.0	4.4	-1.7	0.5	0.0	0.4	-0.9	-0.8	-0.7	-0.9	-0.1	-0.5	-0.1	-0.9	-2.1	-1.6	-1.4	-0.6	0.8
Asthma	0.7	1.3	5.4	-1.2	1.6	0.1	-0.6	1.2	-0.0	0.3	-0.6	-0.4	-0.8	-0.4	-0.3	-2.0	-1.9	-1.2	-2.3	-0.8
Exposure to tobacco smoke at home	0.7	0.8	1.8	1.3	-0.4	-1.2	-1.2	-0.8	-0.8	-0.4	-1.0	-0.9	-0.6	-1.1	-0.3	-0.0	1.2	1.0	0.9	-0.3
Headache pain in last month	0.7	1.1	4.4	-0.4	1.6	0.9	0.3	2.0	1.2	1.2	0.7	0.0	0.4	0.2	0.8	-0.9	-0.6	-0.2	-1.3	-2.1
Number of full brothers	0.7	0.8	4.0	1.4	-1.0	-0.2	-0.3	0.9	0.5	0.5	0.6	0.3	0.2	0.4	0.2	2.0	1.1	1.1	1.5	-0.3
Health satisfaction	0.7	0.9	3.4	1.9	-0.6	-0.9	-0.7	0.1	-0.4	-0.4	-0.1	-0.8	-0.4	-0.7	-0.3	-0.6	1.7	1.7	1.5	0.3
Emphysema/chronic bronchitis	0.7	0.8	4.9	-0.2	2.2	0.5	0.2	1.1	0.5	0.7	1.2	0.1	0.4	0.1	0.8	0.1	-0.5	-0.2	-1.6	-1.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.7	0.9	2.8	1.7	0.3	-0.9	-0.7	-0.7	-0.5	-0.5	0.1	-0.6	-0.3	-0.7	-0.2	1.4	1.7	1.6	0.9	0.2
Alcohol intake frequency.	0.7	1.6	5.4	-0.2	2.1	1.5	-0.4	1.7	1.6	1.2	2.3	0.3	0.4	0.3	1.6	0.8	0.6	0.1	-1.4	-1.4
Asthma (self-reported)	0.7	1.4	6.9	-1.2	1.7	0.2	-0.5	1.5	0.2	0.6	-0.5	-0.4	-0.6	-0.2	-0.1	-1.9	-1.8	-1.1	-2.6	-1.2
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.7	1.5	3.1	-1.6	0.3	-1.1	-0.0	-1.5	-1.3	-1.2	-1.0	-0.8	-0.7	-0.9	-1.6	-1.8	-1.7	-1.7	-1.1	0.7
Wears glasses or contact lenses	0.7	0.8	4.2	0.3	-0.2	-1.3	-1.0	0.7	-0.1	0.0	-2.1	-1.0	-0.9	-0.9	-0.5	0.3	-0.2	-0.0	-1.1	-1.4
Eye problems/disorders: Glaucoma	0.7	0.9	2.2	-0.5	0.5	-1.5	-0.5	-0.2	-0.7	-0.9	-0.3	-1.3	-1.0	-1.5	-1.4	-1.3	-0.8	-0.7	-0.8	-0.4
Medication: Paracetamol	0.7	1.1	3.8	-1.5	1.4	0.8	0.4	1.9	0.8	0.9	0.6	0.3	0.3	0.6	0.5	0.4	-1.1	-1.5	-1.9	-0.8
Average weekly beer plus cider intake	0.7	1.1	3.0	0.3	-1.5	-1.7	-0.1	-1.4	-1.4	-1.1	-1.1	0.2	-0.7	-0.1	-1.4	-0.6	-0.5	-0.1	1.4	1.3
Fractured/broken bones in last 5 years	0.7	1.0	2.4	0.8	-1.5	-1.2	-0.1	-1.0	-1.2	-1.4	-1.3	-0.7	-0.4	-0.9	-1.0	0.9	-0.2	0.5	1.0	1.1
Deep venous thrombosis (DVT) (self-reported)	0.7	0.9	3.1	-0.8	1.4	0.7	1.8	0.0	0.2	0.9	0.8	1.3	1.4	1.1	0.5	-0.6	-1.3	-0.6	-0.2	-0.3
Primary Biliary Cirrhosis	0.6	0.9	3.4	-0.6	0.6	-0.4	-0.8	-0.2	-0.3	-0.4	-1.8	-1.0	-0.9	-0.9	-0.5	-1.8	-0.8	-0.8	-1.3	-0.5
Blood Platelet Count	0.6	7.0	25.1	-0.5	3.1	2.0	1.3	3.6	2.7	4.2	2.4	1.8	2.1	1.9	3.1	-2.1	0.2	0.1	-2.9	-5.0
Relative age of first facial hair	0.6	1.2	4.6	1.6	-0.1	-0.2	-1.4	-0.4	-0.3	-0.7	0.2	-1.0	-0.7	-0.9	-0.1	2.0	2.1	1.4	1.3	0.7
Diverticular disease/diverticulitis (self-reported)	0.6	0.7	1.8	-0.0	1.2	0.9	0.9	0.0	1.0	0.3	1.3	1.1	0.8	0.9	0.7	-0.4	0.4	0.6	0.6	1.4
Fluid intelligence score	0.6	1.2	4.5	-2.1	1.2	1.0	0.5	0.7	0.7	0.3	0.4	0.5	0.0	0.2	-0.0	-1.1	-1.8	-2.0	-1.6	-0.1
Forced expiratory volume in 1-second (FEV1)	0.6	2.0	5.3	-2.0	2.3	1.4	0.9	1.1	1.2	0.8	1.3	1.3	0.8	1.2	0.8	-1.2	-2.1	-1.9	-1.8	0.1
Medication: Ibuprofen (e.g. Nurofen)	0.6	0.7	2.1	-0.9	-1.3	-0.8	0.6	-0.3	-1.0	-0.8	-0.5	0.1	-0.3	0.2	-1.3	-0.6	-1.1	-0.9	0.8	1.4
Pulse wave Arterial Stiffness index	0.6	0.7	2.0	0.7	0.5	-0.8	-1.4	0.1	-0.4	-0.6	-1.0	-1.4	-1.3	-1.3	-0.6	0.7	0.8	0.2	-0.2	-0.3
Birth weight of first child	0.6	1.2	4.1	-1.4	1.0	0.4	1.2	0.3	0.9	1.2	-0.2	0.7	1.0	0.7	0.8	0.2	-1.6	-1.5	-2.0	-1.1
Blood clot in the leg (DVT)	0.6	0.8	2.5	-0.8	1.5	0.5	1.6	-0.0	0.0	0.7	0.5	1.1	1.2	0.8	0.3	-0.9	-1.3	-0.6	-0.2	-0.1
Medication: Paracetamol	0.6	1.0	2.9	-1.3	1.5	0.9	0.5	1.7	0.8	0.9	0.6	0.5	0.3	0.8	0.5	0.6	-1.0	-1.3	-1.5	-0.8
Glaucoma (self-reported)	0.6	0.7	2.3	-0.6	1.5	-0.8	-0.4	0.4	-0.1	-0.3	0.4	-1.0	-0.8	-1.0	-0.7	-1.3	-0.6	-0.9	-1.4	-0.5
Medication: Ventolin 100micrograms inhaler	0.6	0.7	1.6	-0.7	-1.0	-0.3	-1.0	0.6	-0.5	-1.2	-1.1	-1.1	-1.3	-1.2	-0.9	-0.5	-0.6	-0.7	-0.7	0.4
Comparative body size at age 10	0.6	1.7	4.6	-0.6	1.2	1.9	1.0	1.6	1.6	2.1	0.3	1.4	1.2	1.4	1.6	-0.5	0.0	-0.4	-1.1	-1.6
Pulse wave peak to peak time	0.6	0.7	2.0	-0.8	-0.4	1.0	1.4	0.0	0.5	0.6	1.2	1.4	1.2	1.3	0.6	-0.8	-0.9	-0.3	0.1	0.3
Medication: Allopurinol	0.6	0.9	2.0	0.9	-0.3	0.6	0.2	1.4	1.2	1.0	1.2	0.6	0.9	0.7	1.1	1.0	1.3	0.8	0.1	-1.0
Medication: Omeprazole	0.6	0.7	3.4	-0.6	0.3	-0.4	-1.0	0.1	-1.2	-0.7	-1.9	-0.3	-1.0	-0.4	-0.9	-0.9	-0.7	-0.7	-0.6	0.4
Heart disease (mother)	0.6	0.8	3.6	1.8	0.0	0.3	-0.8	-0.3	0.3	0.1	0.8	-0.2	0.1	-0.0	0.7	0.3	1.7	1.9	1.0	-0.5
Commuting to job workplace: Car/motor vehicle	0.6	0.7	2.4	0.3	0.5	1.4	0.4	0.5	1.1	0.8	1.6	0.6	0.8	0.7	1.1	1.0	0.4	0.6	-0.2	-0.2
Back pain experienced in last month	0.6	0.8	3.1	0.4	1.6	0.7	0.5	0.6	1.0	1.3	0.9	0.5	0.9	0.7	1.1	-0.5	0.5	0.5	-0.1	-1.8
Worry (Nagel 2018)	0.5	1.1	6.6	-0.2	2.6	-1.1	-0.9	0.9	-0.1	0.2	0.1	-1.0	-0.9	-1.0	-0.4	-0.9	-0.9	-0.4	-1.6	-1.2
Coronary Artery Disease (CAD)	0.5	0.6	1.9	0.5	0.9	1.0	0.5	1.4	1.2	0.5	-0.7	0.3	0.7	0.6	0.8	1.0	0.3	1.2	0.1	-0.8
BMI	0.5	2.8	9.0	-2.8	0.4	1.8	1.2	2.0	0.9	1.4	-0.3	0.9	0.7	1.1	0.7	-2.2	-1.9	-2.7	-3.0	-1.2
Allergy or Eczema	0.5	1.3	6.1	-0.8	1.5	0.2	-0.4	1.6	0.5	0.6	-0.6	-0.7	-0.6	-0.5	0.0	-1.3	-1.2	-0.7	-2.2	-2.5
Hand grip strength (left)	0.5	1.4	4.5	-0.4	-1.1	1.2	1.7	-0.1	1.1	0.9	2.1	1.9	1.7	1.7	1.1	0.3	-1.0	-0.1	0.1	0.7
Ever had hysterectomy (womb removed)	0.5	0.6	2.0	-0.6	-0.2	0.0	1.3	-0.5	0.1	0.2	1.4	1.0	0.8	0.9	-0.2	0.0	-1.4	-0.8	0.0	0.4
Leg fat-free mass (left)	0.5	2.4	12.5	-2.2	1.8	1.0	-0.2	0.8	-0.1	0.4	0.4	-0.1	-0.2	0.0	0.1	-3.5	-2.0	-2.0	-2.9	-1.2
Frequency of unenthusiasm / disinterest in last 2 weeks	0.5	0.7	2.1	-1.0	0.3	0.5	0.9	-1.1	-0.6	-0.2	0.4	0.9	0.3	0.9	-0.5	-1.3	-1.4	-0.8	0.3	1.2
Qualifications: CSEs or equivalent	0.5	0.6	2.7	0.9	1.0	0.7	0.3	0.5	0.9	1.1	0.4	0.6	0.6	0.7	0.7	0.1	0.6	1.0	0.3	-1.6
Body mass index (BMI)	0.5	2.1	7.5	-2.7	0.2	1.2	0.5	1.7	0.0	0.7	-0.3	0.1	-0.1	0.3	0.0	-2.1	-1.8	-2.6	-2.7	-0.9
Waist circumference	0.5	1.7	5.3	-2.1	0.6	1.1	0.9	1.6	0.2	1.0	-0.2	0.4	0.4	0.7	0.4	-1.8	-1.8	-2.1	-2.3	-1.2
Alcohol usually taken with meals	0.5	0.8	3.0	-0.5	-0.8	-0.1	-0.9	-0.3	-0.7	-1.3	-1.7	-1.1	-1.3	-1.0	-1.1	-0.6	-0.7	-0.4	-0.0	0.4
Forced vital capacity (FVC)	0.5	1.8	4.0	-1.6	2.0	1.3	1.3	1.3	1.5	1.0	1.3	1.6	1.2	1.4	1.2	-0.7	-1.7	-1.4	-1.3	0.2
Arm fat mass (right)	0.5	1.9	7.0	-2.1	0.6	1.0	0.2	2.3	0.1	0.7	-0.2	-0.2	-0.2	0.1	0.1	-2.1	-1.9	-2.0	-2.6	-1.1
Had major operations	0.5	0.6	4.1	-0.6	0.8	0.2	-0.9	0.7	0.2	0.3	-2.0	-0.1	-0.5	-0.2	0.1	-0.6	-0.5	-0.8	-1.4	-0.2
Medication: Aspirin	0.5	0.7	1.9	0.4	-0.1	-1.0	-0.9	-0.1	-0.7	-0.5	-0.5	-1.3	-0.8	-1.4	-0.7	-1.3	0.4	0.3	-0.7	-1.3
Osteoporosis (self-reported)	0.5	0.6	2.4	-1.0	0.1	0.1	-0.0	0.5	-0.4	-0.2	-1.2	0.1	-0.7	0.0	-0.7	-1.5	-1.6	-0.7	-0.4	-0.7
Pain type(s) experienced in last month: Hip pain	0.5	0.6	1.6	-0.3	0.3	0.7	1.0	-0.3	0.9	0.6	0.9	0.8	1.1	0.9	0.9	1.3	0.5	-0.2	0.4	0.8
Arm fat-free mass (left)	0.5	2.5	7.3	-2.7	1.4	2.0	1.4	1.1	0.8	0.5	1.1	0.9	0.8	1.0	0.6	-2.5	-2.3	-2.2	-2.2	-0.3
Ever had prostate specific antigen (PSA) test	0.5	0.6	2.7	-1.3	-0.0	-0.1	0.1	-0.3	-0.5	-0.1	-1.4	-0.1	-0.4	-0.1	-0.8	-0.4	-1.6	-1.3	-1.0	-0.0
Arm predicted mass (left)	0.5	2.7	7.5	-2.7	1.6	2.2	1.4	1.5	1.0	0.7	1.2	1.0	0.9	1.1	0.9	-2.1	-2.3	-2.2	-2.3	-0.5
Intelligence (Savage-Jansen 2018)	0.4	1.3	3.3	-1.7	0.8	1.2	0.7	1.8	1.0	1.0	0.5	1.2	0.7	1.0	0.8	-0.6	-1.6	-1.6	-1.6	-0.4
Crohns Disease (2017)	0.4	0.9	3.3	1.0	1.2	0.5	0.1	1.4	1.1	0.5	1.8	-0.2	0.7	0.0	1.1	-0.6	1.6	1.2	0.5	0.0
Crohns Disease (2012)	0.4	0.7	4.3	0.7	0.4	-0.2	-0.4	0.8	0.5	-0.0	1.7	-0.7	0.1	-0.7	0.3	-2.1	0.9	0.5	-0.4	-0.6
HDL Cholesterol	0.4	0.6	2.9	1.7	0.3	-0.1	-0.6	-0.3	0.3	-0.1	0.7	-0.1	0.1	-0.3	0.3	0.7	1.4	1.6	1.1	-0.4
LDL Cholesterol	0.4	0.6	1.9	-0.5	-0.3	1.1	1.1	1.2	0.8	0.4	0.6	1.0	0.8	1.4	0.6	0.2	-0.1	0.0	-0.0	0.8
Lupus	0.4	0.6	2.1	-1.4	0.7	0.9	0.8	0.4	-0.2	0.4	-0.4	0.6	0.5	0.6	0.1	-1.3	-0.9	-1.2	-1.2	-0.3
Neuroticism (2016)	0.4	0.5	2.0	-0.1	-0.3	-0.4	-0.2	-1.2	-0.8	-1.1	-0.7	-0.5	-0.6	-0.4	-0.8	-0.9	-0.3	-0.3	0.5	1.4
Respiratory disease	0.4	0.8	2.9	-1.1	1.7	0.5	-0.1	1.2	0.1	0.6	-0.0	0.2	-0.1	0.1	0.1	-1.2	-1.4	-1.0	-1.7	-0.9
Type 2 Diabetes (T2D) (2018)	0.4	0.7	5.2	0.3	1.0	0.2	-0.4	1.2	0.2	-0.3	2.3	-0.5	-0.3	-0.5	-0.1	-0.7	0.6	0.7	-0.3	-1.0
Medication: Metformin	0.4	0.6	2.1	0.5	0.4	-0.1	-1.4	0.3	-0.4	-0.5	1.3	-1.0	-1.1	-1.0	-0.4	-0.6	0.8	0.7	0.1	-0.4
Average weekly fortified wine intake	0.4	0.4	2.8	-0.5	-0.9	-0.8	0.3	-0.1	-0.3	-0.6	-0.9	-0.4	-0.2	-0.5	-0.8	0.1	-1.7	-0.6	-0.5	0.0
Bilateral oophorectomy (both ovaries removed)	0.4	0.5	1.9	0.2	-0.4	-0.4	1.4	-0.6	-0.0	0.1	-0.1	0.9	0.9	0.8	-0.2	1.1	-0.7	0.2	0.9	0.6
Leg predicted mass (left)	0.4	2.3	12.3	-2.2	1.8	1.0	-0.3	0.8	-0.1	0.3	0.4	-0.2	-0.3	-0.0	0.0	-3.5	-2.0	-2.0	-2.8	-1.2
Weight	0.4	1.8	6.9	-1.9	1.1	0.9	0.0	1.6	0.1	0.5	-0.1	-0.3	-0.2	-0.0	0.1	-2.6	-1.8	-1.8	-2.6	-0.9
Trunk fat-free mass	0.4	2.2	8.4	-2.5	1.7	1.3	0.6	0.6	0.2	-0.0	0.9	0.2	0.2	0.3	0.1	-2.9	-2.5	-2.1	-2.3	-0.4
Pulse rate	0.4	0.6	2.4	0.1	0.6	-0.8	-1.2	0.4	-0.5	-0.1	-0.6	-1.2	-0.8	-1.1	-0.3	0.3	-0.3	-0.0	-1.5	-1.3
Happiness	0.4	0.5	1.5	0.3	0.9	0.9	0.6	-0.1	0.5	0.2	1.2	0.6	0.7	0.7	0.8	-1.0	0.6	0.5	0.7	0.4
Trunk predicted mass	0.4	2.3	8.5	-2.6	1.8	1.4	0.7	0.6	0.2	0.0	0.9	0.3	0.2	0.4	0.1	-2.9	-2.5	-2.2	-2.4	-0.4
Hair/balding pattern: Pattern 4	0.4	1.1	4.4	-0.5	-1.0	-1.4	-0.2	0.1	-1.4	-0.8	-1.5	-0.6	-1.0	-0.8	-1.6	-2.1	-0.7	-0.7	-0.2	-0.2
Loud music exposure frequency	0.4	0.5	1.3	0.5	-0.5	0.2	0.7	0.7	0.6	0.9	0.7	0.7	0.9	0.9	0.7	0.7	0.5	0.5	1.2	-0.1
Qualifications: O levels/GCSEs or equivalent	0.4	0.6	1.6	-0.0	-0.5	-1.2	-0.4	-1.3	-0.9	-0.9	-1.1	-0.8	-0.8	-1.0	-1.1	-0.9	0.0	-0.3	0.6	0.2
High blood pressure (siblings)	0.4	0.5	2.6	0.5	-0.2	-0.9	0.2	-1.6	-1.0	-0.6	-1.1	-0.4	-0.2	-0.4	-0.9	-0.8	0.4	0.4	0.6	-0.0
Leg fat mass (right)	0.4	1.7	7.5	-1.2	1.0	1.4	0.5	2.7	1.2	1.4	0.2	0.2	0.5	0.5	1.1	-1.0	-0.7	-1.1	-2.3	-1.7
Arm predicted mass (right)	0.4	1.8	5.1	-2.2	1.5	1.9	1.2	0.7	0.6	0.4	0.9	0.7	0.8	0.9	0.6	-2.3	-1.8	-1.8	-1.9	-0.4
Whole body fat-free mass	0.4	2.3	9.9	-2.5	1.8	1.4	0.4	0.7	0.1	0.1	0.8	0.2	0.1	0.3	0.1	-3.1	-2.3	-2.2	-2.5	-0.5
Leg fat-free mass (right)	0.4	2.4	13.4	-2.4	1.6	0.9	-0.2	0.4	-0.4	0.0	0.2	-0.2	-0.3	-0.0	-0.2	-3.7	-2.2	-2.3	-2.7	-0.6
Medication: Aspirin	0.4	0.6	1.7	0.7	-0.4	-1.0	-0.7	-0.1	-0.7	-0.5	-0.5	-1.2	-0.5	-1.3	-0.5	-0.6	0.6	0.6	-0.5	-1.2
Medication: Gliclazide	0.4	0.4	2.2	-0.7	1.1	0.8	0.0	1.5	0.5	0.4	0.1	0.6	0.0	0.4	0.4	-0.1	-0.6	-0.4	-1.0	-0.5
Whole body water mass	0.4	2.5	10.6	-2.6	1.8	1.4	0.5	0.7	0.1	0.2	0.7	0.2	0.1	0.3	0.1	-3.2	-2.4	-2.3	-2.6	-0.7
Leg predicted mass (right)	0.4	2.3	13.3	-2.3	1.6	1.0	-0.1	0.5	-0.3	0.1	0.3	-0.1	-0.3	0.0	-0.1	-3.6	-2.1	-2.2	-2.6	-0.6
Arm fat mass (left)	0.4	1.5	5.4	-1.9	0.5	1.0	0.2	2.0	0.1	0.8	-0.3	-0.1	-0.1	0.1	0.1	-2.0	-1.6	-1.8	-2.3	-1.1
Number of self-reported non-cancer illnesses	0.4	0.7	2.1	-0.0	1.1	-0.8	-1.1	0.2	-0.7	-0.5	-0.8	-1.2	-1.0	-1.2	-0.7	-1.5	-0.2	-0.3	-0.9	-0.6
Mother’s age at death	0.4	0.5	1.4	0.5	-0.6	-1.2	-0.5	-0.7	-0.5	-0.7	-0.5	-0.9	-0.6	-0.9	-0.7	-0.7	0.4	0.2	1.1	0.2
Tinnitus: Yes, now most or all of the time	0.4	0.4	3.2	0.1	0.0	-0.3	-0.8	-0.6	-0.7	-0.4	-0.6	-0.6	-0.8	-0.6	-0.3	-1.8	0.7	0.4	0.3	0.1
Commuting to job workplace: Public transport	0.4	0.4	1.8	0.7	0.4	0.1	0.2	0.5	0.4	0.6	-0.4	0.4	0.6	0.4	0.8	-0.3	1.3	0.9	0.3	-1.2
Basal metabolic rate	0.4	2.3	9.4	-2.5	1.6	1.4	0.4	1.0	0.2	0.3	0.7	0.2	0.1	0.3	0.2	-3.1	-2.3	-2.2	-2.6	-0.6
Pain experienced in last month	0.4	0.6	2.4	0.5	-1.5	-0.2	0.2	-1.0	-0.6	-0.2	-0.4	0.6	0.1	0.5	-0.1	1.5	0.6	0.8	1.0	1.3
Supplements: Calcium	0.4	0.5	2.4	-1.3	-0.4	0.3	0.1	0.4	-0.5	-0.4	-0.0	0.3	-0.4	0.2	-0.5	-0.7	-1.6	-1.2	-0.4	0.8
Pack years of smoking	0.4	0.5	3.2	0.1	0.2	0.6	0.1	1.8	0.6	0.9	0.7	0.5	0.2	0.4	0.7	1.5	0.1	-0.0	0.1	-0.6
Leg fat mass (left)	0.4	1.6	6.7	-1.3	0.9	1.4	0.7	2.6	1.2	1.4	0.0	0.4	0.6	0.7	1.1	-1.0	-0.7	-1.2	-2.3	-1.4
Age at First Birth	0.3	0.4	2.6	0.9	-0.1	0.2	-0.7	0.7	0.1	0.2	0.2	-0.1	-0.2	-0.0	0.4	1.6	0.5	1.0	0.1	-1.2
Lung FEV1/FVC ratio	0.3	1.6	6.8	-2.0	1.4	-0.1	0.3	-1.4	-0.9	-0.9	-0.3	-0.5	-0.6	-0.2	-1.3	-2.6	-1.6	-2.0	-0.8	0.5
Lung FVC	0.3	1.4	2.8	-1.3	1.2	1.4	1.2	1.7	1.3	1.1	0.8	1.4	1.3	1.3	1.3	0.8	-0.6	-1.3	-1.1	-0.3
Pack years adult smoking proportion	0.3	0.5	2.5	-0.0	-0.0	0.7	0.4	1.6	0.5	0.7	1.1	0.6	0.3	0.5	0.6	1.6	-0.0	-0.1	0.4	-0.2
Current tobacco smoking	0.3	0.6	3.0	-1.0	0.1	0.1	1.0	-0.1	-0.3	0.3	1.7	0.7	0.5	0.6	-0.1	-0.2	-0.7	-1.1	0.1	1.2
Maternal smoking around birth	0.3	0.4	2.1	-0.2	0.4	0.2	-0.6	0.9	0.4	-0.2	0.6	-0.6	-0.3	-0.7	0.2	-1.4	0.0	-0.4	-0.9	-0.6
Relative age voice broke	0.3	0.4	3.7	0.4	0.6	0.2	-0.5	0.9	0.6	0.4	0.4	-0.2	-0.2	-0.3	0.2	1.9	0.5	0.2	0.1	-0.4
Stomach or abdominal pain in last month	0.3	0.4	1.6	-1.1	0.5	0.3	0.1	0.1	0.4	-0.5	-0.6	0.4	-0.3	0.3	-0.3	-0.6	-1.3	-0.9	-0.5	1.1
Had menopause	0.3	0.3	1.9	-0.4	-1.0	0.1	0.3	-0.3	-0.3	-0.1	-0.7	0.6	0.1	0.3	-0.1	-1.4	-0.7	-0.6	-0.1	-0.2
Ever unenthusiastic/disinterested for a whole week	0.3	0.3	1.6	-0.0	-1.3	-0.1	-0.0	0.1	0.2	-0.2	0.9	0.1	-0.4	0.1	-0.3	0.9	-0.3	0.0	0.6	1.2
Medication: Simvastatin	0.3	0.4	1.5	0.9	-0.6	-0.6	-0.1	0.1	-0.2	-0.5	0.8	-0.4	-0.2	-0.5	-0.3	0.4	0.9	1.2	0.9	-0.1
Neuroticism score	0.3	0.6	3.8	-0.1	2.0	-0.5	-0.5	0.1	-0.5	-0.6	0.2	-0.8	-0.8	-0.7	-0.5	-1.3	-0.7	-0.3	-0.1	1.1
Arm fat percentage (right)	0.3	1.2	4.5	-1.4	0.1	0.1	-0.7	2.0	-0.5	0.3	-0.9	-0.9	-0.9	-0.6	-0.4	-1.6	-1.2	-1.4	-2.1	-1.0
Hip circumference	0.3	1.3	7.6	-1.3	-0.3	-0.3	-0.7	0.5	-0.9	-0.4	-0.8	-1.2	-1.0	-0.9	-0.8	-2.8	-1.0	-1.4	-1.9	-0.5
Qualifications: A levels/AS levels or equivalent	0.3	0.6	1.7	-0.1	-1.2	-0.5	-0.9	-0.8	-0.6	-1.0	-1.3	-0.9	-1.0	-1.0	-0.8	-1.1	0.2	-0.0	0.3	0.4
Serious illness, injury or assault of a close relative in last 2 years	0.3	0.3	2.3	-0.9	0.2	0.4	-0.4	0.0	0.3	0.2	0.0	-0.1	-0.3	0.1	0.2	-0.5	-0.5	-1.2	-1.5	-0.2
Tense / ‘highly strung’	0.3	0.5	3.9	0.1	2.0	-0.5	-0.8	0.4	-0.3	-0.5	0.2	-0.6	-0.6	-0.5	-0.3	-0.9	-0.4	-0.1	-0.5	-0.3
Peak expiratory flow (PEF)	0.3	0.6	3.0	-0.7	1.7	0.0	-0.5	0.9	-0.2	-0.0	0.7	-0.4	-0.6	-0.4	-0.4	-1.1	-0.8	-0.6	-1.5	-0.5
Ever highly irritable/argumentative for 2 days	0.3	0.4	3.1	-0.2	-0.7	0.0	0.7	0.2	-0.0	0.1	1.8	0.7	0.4	0.6	0.1	-0.6	0.0	-0.3	0.6	0.9
Gout (self-reported)	0.3	0.4	1.4	0.9	-0.1	0.3	0.3	0.9	0.6	0.3	0.5	0.4	0.6	0.5	0.5	0.7	1.2	0.9	0.5	-0.1
Leg fat percentage (right)	0.3	1.2	7.6	-0.8	-0.0	1.1	0.8	2.8	1.2	1.4	-0.0	0.3	0.7	0.6	1.1	0.5	-0.2	-0.7	-1.7	-1.3
Arm fat-free mass (right)	0.3	1.8	4.4	-2.1	1.6	1.9	1.2	0.9	0.8	0.5	1.0	0.8	0.9	0.9	0.8	-2.0	-1.6	-1.7	-1.8	-0.5
Exposure to tobacco smoke outside home	0.3	0.4	1.6	0.8	0.2	-0.5	-1.1	0.1	-0.1	0.1	-0.1	-0.9	-0.7	-0.8	0.0	0.3	0.9	0.4	-0.3	-1.3
Number of children fathered	0.3	0.3	0.8	-0.7	-0.9	-0.7	0.2	-0.4	-0.4	-0.5	-0.6	-0.0	-0.1	-0.3	-0.6	-0.4	-0.5	-0.9	-0.7	0.6
Mouth/teeth dental problems: Loose teeth	0.3	0.3	1.1	0.0	-0.1	-0.5	-0.5	-0.1	0.1	-0.4	-1.0	-0.7	-0.7	-0.9	-0.7	0.7	-0.5	-0.1	-0.3	-0.2
Pulse rate, automated reading	0.3	1.1	3.5	-0.5	0.7	-1.0	-1.0	1.1	-0.6	-0.4	-1.3	-1.3	-1.1	-1.5	-0.8	0.6	-1.1	-0.6	-1.9	-1.1
Comparative height size at age 10	0.3	1.7	4.7	0.5	2.2	1.5	1.0	1.3	1.8	1.4	1.5	1.2	1.8	1.2	1.9	-0.2	-0.7	1.0	-0.4	-0.5
Qualifications: NVQ or HND or HNC or equivalent	0.3	0.4	1.4	-0.4	-0.2	-1.0	-0.3	-0.5	-1.2	-0.5	0.3	-0.2	-0.6	-0.3	-1.1	0.0	-0.7	-0.8	-0.4	0.0
Knee pain experienced in last month	0.3	0.4	1.9	-1.2	0.3	0.0	-0.6	-0.2	-0.5	-0.7	-0.6	-0.4	-0.8	-0.5	-0.6	0.3	-0.7	-1.4	-0.6	0.1
Arm fat percentage (left)	0.3	1.0	3.8	-1.1	0.1	0.1	-0.6	1.8	-0.4	0.4	-0.9	-0.8	-0.7	-0.6	-0.3	-1.6	-1.0	-1.2	-2.0	-1.1
Handedness (chirality/laterality): Left-handed	0.3	0.3	0.9	-0.1	0.4	0.4	0.9	-0.3	0.4	0.9	0.0	0.9	0.9	0.9	0.4	-0.1	0.1	0.0	0.2	-0.9
Qualifications: nursing, teaching	0.3	0.5	1.4	0.7	-1.2	-0.1	-0.3	-1.2	-0.2	-0.6	0.0	-0.2	-0.1	-0.1	0.0	0.7	0.9	0.9	1.1	1.0
Guilty feelings	0.3	0.5	2.0	0.3	1.4	0.7	-0.2	1.0	0.8	0.4	1.4	0.2	0.1	0.3	0.5	-0.8	-0.4	0.4	-0.1	0.1
Financial situation satisfaction	0.3	0.4	1.7	0.4	-0.2	0.8	0.4	-0.2	0.8	0.5	1.3	0.7	0.5	0.6	0.8	-0.5	0.3	0.6	0.8	0.6
Medication: Atorvastatin	0.3	0.3	0.8	0.9	0.4	-0.7	-0.8	0.1	-0.5	-0.3	0.5	-0.8	-0.5	-0.6	-0.3	-0.2	0.7	0.9	-0.2	0.2
Leg fat percentage (left)	0.3	1.0	6.6	-0.8	-0.2	1.0	0.8	2.6	1.1	1.2	-0.4	0.3	0.7	0.6	1.0	0.5	-0.2	-0.7	-1.5	-0.8
Myopia	0.3	0.4	1.2	-0.1	0.8	0.5	0.0	1.1	0.9	0.8	0.9	0.2	0.4	0.5	0.9	0.3	0.3	-0.3	-0.4	-0.5
Cholesterol lowering medication	0.3	0.4	0.8	0.3	-0.7	-0.6	-0.2	-0.9	-0.6	-0.8	0.7	-0.8	-0.5	-0.8	-0.9	0.2	0.2	0.5	0.6	-0.5
Heart disease (siblings)	0.3	0.4	2.2	0.8	-1.5	-0.9	0.1	-0.3	-0.1	-0.1	0.7	-0.2	-0.0	-0.4	-0.4	0.3	0.5	0.7	1.3	-0.4
Alcohol drinker status: Previous	0.3	0.3	1.5	-0.6	-0.2	0.1	0.7	-0.4	0.7	0.1	0.7	0.2	0.6	0.2	0.5	0.5	0.3	-0.5	-0.0	1.2
Depressed Affect (Nagel 2018)	0.2	0.4	1.2	-0.6	0.2	0.6	1.1	0.0	0.5	0.4	0.6	0.8	0.7	1.0	0.5	0.0	-0.7	-0.3	0.4	0.8
Depression (Nagel 2018)	0.2	0.3	1.7	-0.5	0.3	-0.2	0.6	-1.3	-0.5	0.1	-0.3	0.4	0.1	0.5	-0.3	-1.0	-0.7	-0.6	-0.0	0.1
Neuroticism (Nagel 2018)	0.2	0.6	1.5	-0.2	1.2	-1.1	-0.6	-0.2	-0.6	-0.8	-0.4	-1.0	-0.9	-0.9	-0.8	-1.1	-0.8	-0.3	-0.1	0.5
Reaction Time	0.2	0.5	1.5	0.3	0.2	1.1	0.5	-0.6	1.1	0.5	0.4	0.8	0.8	0.9	1.2	-0.0	0.7	0.2	0.2	0.3
Hair Pigment	0.2	4.9	11.5	-0.0	-1.7	-2.6	-2.3	-1.9	-2.8	-3.4	-2.0	-3.1	-2.9	-3.1	-3.0	-1.1	-0.0	-0.3	0.5	1.7
Sensitivity / hurt feelings	0.2	0.3	2.9	-0.0	0.4	-0.2	0.3	-0.4	-0.5	-0.8	0.1	-0.5	-0.2	-0.2	-0.4	-0.8	-0.2	0.0	0.5	1.7
Ever used hormone-replacement therapy (HRT)	0.2	0.3	1.2	0.4	-0.9	-0.2	1.1	0.3	0.2	0.3	1.1	0.5	0.6	0.3	-0.0	-0.2	0.3	0.4	0.4	-0.3
Vitamin and mineral supplements	0.2	0.2	1.1	-0.3	-0.5	-0.2	-0.5	-0.0	-0.3	-0.0	0.8	-0.3	-0.4	-0.3	-0.2	-0.3	-0.5	-1.0	-0.9	-0.6
Diabetes (father)	0.2	0.3	0.9	-0.9	0.3	-0.3	0.3	0.1	-0.2	-0.8	0.1	-0.4	-0.3	-0.4	-0.6	-0.8	-0.9	-0.7	-0.1	0.2
Diabetes (mother)	0.2	0.2	1.5	-0.2	0.5	-0.2	0.4	0.7	0.1	0.4	0.1	-0.1	0.3	-0.2	0.1	-1.2	0.1	-0.3	-0.5	-0.6
Taking other prescription medications	0.2	0.3	3.7	-0.2	0.6	0.4	0.0	1.9	0.2	0.4	0.6	0.3	0.1	0.4	0.2	0.1	-0.2	-0.2	-0.5	-0.2
Age when periods started (menarche)	0.2	0.5	1.9	0.1	-0.2	-0.9	-0.4	-1.0	-0.7	0.0	-1.4	-0.2	-0.4	-0.2	-0.5	-1.4	-0.0	-0.2	-0.4	-1.2
Supplements: Glucosamine	0.2	0.3	1.3	-0.3	-0.1	-0.4	-0.6	-0.3	-0.1	-0.7	-1.0	-0.2	-0.6	-0.3	-0.6	1.2	-0.0	-0.3	0.4	0.7
Trunk fat mass	0.2	0.7	5.0	-0.4	0.6	0.7	-0.1	2.2	0.6	0.9	-0.2	-0.3	0.1	0.0	0.6	-0.9	-0.3	-0.3	-1.5	-0.9
Hair/balding pattern: Pattern 2	0.2	0.2	0.6	-0.3	0.8	0.8	-0.0	0.2	0.7	0.3	0.2	0.0	0.1	0.1	0.3	0.0	-0.6	-0.1	-0.6	-0.7
Had other major operations	0.2	0.2	1.0	0.3	-0.6	-0.0	0.5	-0.2	0.1	-0.0	0.7	0.5	0.4	0.5	0.1	0.6	0.7	0.3	1.0	0.5
Diabetes (self-reported)	0.2	0.3	2.2	0.0	-0.0	0.8	0.3	1.2	0.5	0.2	1.5	0.3	0.4	0.3	0.4	-0.6	0.4	0.5	0.0	-0.4
Worrier / anxious feelings	0.2	0.4	1.8	-0.8	1.4	0.4	0.7	0.5	0.8	0.2	0.8	-0.1	0.2	-0.1	0.3	-0.8	-0.7	-0.7	-0.8	-0.1
Noisy workplace	0.2	0.2	0.6	-0.6	-0.1	-0.2	0.6	0.4	0.3	0.3	0.5	0.6	0.5	0.5	0.1	0.4	-0.3	-0.8	-0.2	0.6
Depression (self-reported)	0.2	0.3	0.8	-0.3	0.8	-0.3	-0.7	-0.7	-0.8	-0.4	0.4	-0.4	-0.5	-0.4	-0.4	-0.9	-0.2	-0.5	-0.4	0.3
Forced expiratory volume in 1-second (FEV1), Best measure	0.2	0.7	2.7	-1.4	1.2	0.4	0.2	0.1	0.1	-0.2	0.7	0.4	0.2	0.4	-0.1	-1.3	-1.6	-1.4	-0.9	0.8
Breastfed as a baby	0.2	0.2	0.7	0.5	0.8	-0.6	-0.8	0.4	-0.3	-0.3	-0.2	-0.5	-0.5	-0.7	-0.2	0.3	0.5	0.3	-0.2	-0.2
Forced vital capacity (FVC), Best measure	0.2	0.6	1.6	-0.9	1.3	0.7	0.4	0.7	0.7	0.3	1.3	0.7	0.6	0.6	0.5	-0.3	-1.3	-0.9	-0.8	0.6
Body fat percentage	0.2	0.6	5.5	-0.2	0.1	0.4	-0.2	2.3	0.5	0.8	-0.6	-0.5	-0.1	-0.2	0.5	-0.2	0.0	-0.2	-1.3	-1.0
Medication for pain relief, constipation, heartburn	0.2	0.3	2.4	-0.3	-0.4	-0.0	-0.1	-1.6	-0.2	-0.7	-0.4	-0.2	-0.2	-0.3	-0.2	-0.0	-0.2	-0.1	0.1	1.1
Whole body fat mass	0.2	0.9	5.7	-0.8	0.7	0.9	0.2	2.4	0.7	1.0	-0.2	-0.2	0.2	0.1	0.6	-1.0	-0.6	-0.7	-1.8	-1.1
Supplements: Vitamin C	0.2	0.2	1.1	-0.4	-0.1	0.6	1.1	-0.2	0.0	0.1	0.0	0.4	0.5	0.3	0.0	0.5	-0.8	-0.2	0.2	0.2
Mood swings	0.2	0.4	2.1	0.5	0.1	-0.4	-0.5	-0.9	-0.5	-0.8	0.3	-0.3	-0.5	-0.2	-0.4	0.1	0.4	0.3	0.8	1.4
Loneliness, isolation	0.2	0.2	1.2	0.1	1.1	0.1	0.3	0.4	0.0	0.3	1.0	0.5	0.2	0.5	0.2	-0.2	-0.5	0.2	-0.1	0.5
Diabetes diagnosed by doctor	0.2	0.2	2.4	-0.1	-0.0	0.4	-0.1	1.0	-0.0	-0.1	1.5	-0.2	-0.1	-0.2	-0.0	-0.4	0.2	0.4	-0.2	-0.4
Smoking status: Current	0.2	0.4	2.4	-0.7	0.3	-0.0	0.8	-0.1	-0.2	0.3	1.5	0.6	0.4	0.4	-0.0	-0.3	-0.3	-0.8	0.2	1.1
Average weekly champagne plus white wine intake	0.2	0.3	2.0	-0.1	-0.2	0.5	0.3	-0.5	0.2	-0.2	-1.0	0.1	0.1	0.3	0.2	-0.1	-0.3	0.4	1.1	1.4
Miserableness	0.2	0.4	3.0	-0.7	0.0	-0.2	-0.2	0.4	-0.3	-0.8	0.1	-0.5	-0.6	-0.4	-0.5	-1.0	-0.4	-0.6	0.1	1.7
High cholesterol (Self-reported)	0.2	0.4	0.9	0.9	-0.9	-0.8	0.0	-0.3	-0.4	-0.7	0.1	-0.8	-0.1	-0.7	-0.6	0.8	0.9	0.9	0.6	-0.1
Alcohol drinker status: Never	0.2	0.2	1.0	0.9	0.2	-0.2	-0.3	0.1	0.1	0.6	0.3	-0.1	0.0	-0.1	0.3	0.9	0.5	0.5	-0.0	-1.0
Ever depressed for a whole week	0.2	0.3	1.6	0.1	-0.0	0.5	0.4	-0.0	0.8	0.6	1.3	0.5	0.4	0.6	0.6	-0.2	0.2	0.1	0.4	0.4
Medication: Omeprazole (e.g. Zanprol)	0.2	0.3	2.4	-0.2	0.6	0.1	-0.6	0.8	-0.5	0.1	-1.6	0.2	-0.5	0.2	-0.2	-0.6	-0.4	-0.2	-0.3	-0.0
Mean Putamen Volume	0.1	0.1	0.5	-0.7	0.3	0.1	0.1	-0.2	-0.1	0.1	0.4	0.2	0.0	0.2	-0.1	-0.1	-0.1	-0.6	-0.1	-0.4
Triglycerides	0.1	0.2	1.5	-1.0	-0.3	-0.0	0.5	0.0	-0.1	0.0	-0.1	-0.1	0.1	-0.0	-0.0	-0.4	-0.7	-1.2	-0.5	-0.0
Height	0.1	2.2	9.4	3.1	2.7	-1.2	-0.2	1.3	1.4	0.5	1.2	-0.8	0.8	-0.7	1.1	0.9	0.6	3.0	1.1	-0.6
Neuroticism	0.1	0.3	1.0	-0.3	1.0	-0.5	-0.4	0.7	-0.2	-0.4	-0.2	-0.7	-0.8	-0.6	-0.4	-0.4	-1.0	-0.5	-0.2	0.8
Tanning	0.1	1.3	5.0	2.0	0.3	-0.2	-0.1	0.6	1.2	1.1	0.5	0.1	0.7	0.5	1.1	1.0	2.2	2.0	0.9	-1.2
Trunk fat percentage	0.1	0.5	4.7	0.3	0.0	0.3	-0.4	2.2	0.5	0.8	-0.5	-0.5	-0.1	-0.2	0.5	-0.2	0.4	0.2	-0.8	-0.7
Townsend deprivation index at recruitment	0.1	0.2	1.0	-0.3	-0.5	0.1	-0.0	-0.0	-0.0	-0.6	-0.3	0.0	-0.2	-0.1	-0.3	0.1	-0.2	-0.4	0.6	1.0
Multivitamins +/- minerals	0.1	0.1	0.5	-0.5	0.7	0.0	0.4	0.2	0.2	0.3	-0.7	0.3	0.2	0.2	-0.2	-0.5	-0.5	0.2	-0.1	-0.1
Sitting height	0.1	1.1	2.6	1.0	-0.6	-1.1	-0.9	-1.1	-0.9	-1.6	-0.6	-1.2	-0.9	-1.2	-1.0	-1.4	0.5	0.9	0.8	0.9
Medication: Ramipril	0.1	0.1	0.4	0.6	0.2	-0.3	-0.6	0.2	-0.2	0.1	0.4	-0.5	-0.3	-0.4	-0.0	-0.4	0.5	0.4	-0.2	0.0
Standing height	0.1	0.6	3.2	1.3	1.8	-0.2	-0.7	-0.1	0.6	-0.3	0.7	-0.6	-0.0	-0.5	0.5	-1.2	-0.2	1.4	0.1	0.1
Qualifications: College or University degree	0.1	0.3	2.2	-0.5	-1.5	0.2	-0.4	-0.9	-0.1	-0.1	-0.7	-0.2	-0.5	-0.2	-0.2	-0.6	-0.6	-0.4	-0.5	-0.8
Mean time to correctly identify matches	0.1	0.2	0.9	0.3	-0.4	0.1	-0.3	-0.9	0.6	-0.5	-0.5	-0.3	-0.2	-0.1	0.3	-0.0	0.6	0.2	0.3	0.8
Illnesses of siblings: Diabetes	0.1	0.2	0.8	-0.1	0.1	-0.1	-0.4	-0.2	0.1	-0.3	0.8	-0.4	-0.2	-0.4	0.0	-0.9	0.0	-0.3	-0.2	0.7

Hub : Genes

PRKD3

Models

Trait associations