Best TWAS P=7.45e-09 · Best GWAS P=1.4e-19 conditioned to 6.41e-15
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Artery Tibial | RP11-10C24.2 | 0.11 | 0.06 | lasso | 3 | 0.05 | 8.9e-05 | -6.1 | -5.6 | 2.6e-08 | -0.10 | 0.01 | 0.99 | FALSE |
2 | GTEx | Skin Sun Exposed Lower leg | CRTAP | 0.09 | 0.00 | enet | 23 | 0.01 | 2.1e-02 | -2.9 | -5.8 | 7.4e-09 | -0.27 | 0.11 | 0.15 | TRUE |