Best TWAS P=3.44e-15 · Best GWAS P=6.08e-148 conditioned to NaN
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | ULK4 | 0.49 | 0.63 | enet | 43 | 0.66 | 4.3e-109 | -4.3 | -6.0 | 2.1e-09 | 0.10 | 1.00 | 0.00 | TRUE |
| 2 | GTEx | Artery Coronary | CTNNB1 | 0.30 | 0.00 | lasso | 4 | 0.01 | 1.0e-01 | 6.1 | -5.3 | 1.4e-07 | 0.26 | 0.06 | 0.07 | TRUE |
| 3 | GTEx | Colon Sigmoid | ZNF619 | 0.31 | -0.01 | enet | 9 | 0.00 | 3.3e-01 | 1.5 | 5.2 | 2.2e-07 | 0.07 | 0.08 | 0.24 | TRUE |
| 4 | GTEx | Colon Transverse | ULK4 | 0.24 | 0.05 | lasso | 8 | 0.03 | 9.1e-03 | -4.4 | -5.5 | 3.4e-08 | 0.06 | 0.54 | 0.05 | FALSE |
| 5 | GTEx | Nerve Tibial | CTNNB1 | 0.05 | 0.00 | enet | 4 | 0.00 | 2.0e-01 | 5.2 | 5.2 | 2.5e-07 | -0.27 | 0.14 | 0.11 | TRUE |
| 6 | NTR | Blood | CTNNB1 | 0.04 | 0.04 | lasso | 6 | 0.04 | 4.6e-13 | 7.5 | -7.9 | 3.4e-15 | 0.32 | 1.00 | 0.00 | TRUE |
| 7 | The Cancer Genome Atlas | Cervical Squamous Cell Carcinoma | ULK4 | 0.16 | 0.16 | enet | 14 | 0.15 | 8.0e-08 | -4.6 | -5.6 | 2.1e-08 | 0.00 | 0.99 | 0.00 | TRUE |
| 8 | The Cancer Genome Atlas | Brain Lower Grade Glioma | CTNNB1 | 0.07 | 0.01 | enet | 9 | 0.03 | 3.0e-04 | -7.6 | -7.3 | 3.6e-13 | 0.12 | 0.01 | 0.09 | TRUE |
| 9 | The Cancer Genome Atlas | Rectum Adenocarcinoma | ULK4 | 0.29 | 0.23 | blup | 258 | 0.22 | 6.7e-06 | -4.8 | -5.7 | 9.2e-09 | 0.05 | 0.60 | 0.04 | TRUE |
| 10 | The Cancer Genome Atlas | Uterine Corpus Endometrial Carcinoma | ULK4 | 0.23 | 0.15 | enet | 14 | 0.18 | 9.9e-06 | -4.8 | -6.2 | 4.3e-10 | -0.01 | 0.76 | 0.04 | TRUE |