[Hub]/) : Traits : Heel T-Score :

chr4:17,104,059-18,507,692

Best TWAS P=2.12e-23 · Best GWAS P=7.14e-19 conditioned to 0.00416

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous DCAF16 0.21 0.15 lasso 3 0.17 5.1e-14 -8.0 -7.7 1.5e-14 0.72 0.89 0.11 FALSE
2 GTEx Adipose Visceral Omentum DCAF16 0.19 0.06 enet 10 0.11 3.9e-06 -8.0 -7.6 3.6e-14 0.59 0.16 0.69 FALSE
3 GTEx Artery Aorta DCAF16 0.10 0.01 enet 6 0.02 4.7e-02 7.2 -9.7 2.5e-22 0.61 0.11 0.54 FALSE
4 GTEx Artery Tibial DCAF16 0.16 0.16 lasso 5 0.13 1.5e-10 -8.3 -8.9 7.2e-19 0.84 0.07 0.93 FALSE
5 GTEx Breast Mammary Tissue DCAF16 0.12 0.08 lasso 4 0.10 6.4e-06 -8.0 -8.3 1.3e-16 0.71 0.11 0.73 FALSE
6 GTEx Breast Mammary Tissue (Male) DCAF16 0.24 0.03 enet 18 -0.01 4.4e-01 7.1 -7.3 3.7e-13 0.50 0.07 0.33 FALSE
7 GTEx Breast Mammary Tissue (Female) DCAF16 0.16 0.13 lasso 2 0.06 7.8e-03 -8.0 -7.9 2.3e-15 0.78 0.06 0.20 FALSE
8 GTEx Esophagus Mucosa DCAF16 0.10 0.02 lasso 4 0.02 8.3e-03 -8.0 -8.4 4.4e-17 0.77 0.04 0.81 FALSE
9 GTEx Esophagus Muscularis DCAF16 0.16 0.14 lasso 3 0.14 9.3e-09 -8.0 -8.0 1.5e-15 0.79 0.74 0.25 FALSE
10 GTEx Nerve Tibial DCAF16 0.16 0.14 lasso 3 0.14 2.8e-10 -8.0 -8.2 2.7e-16 0.78 0.87 0.13 FALSE
11 GTEx Pituitary DCAF16 0.27 0.20 enet 15 0.19 1.3e-05 -8.0 -7.0 1.8e-12 0.61 0.08 0.26 FALSE
12 GTEx Skin Not Sun Exposed Suprapubic DCAF16 0.16 0.08 lasso 5 0.12 4.4e-07 -7.6 -8.1 7.0e-16 0.75 0.30 0.55 FALSE
13 GTEx Skin Sun Exposed Lower leg DCAF16 0.14 0.12 enet 14 0.12 5.4e-10 -8.0 -8.6 6.0e-18 0.80 0.44 0.56 FALSE
14 GTEx Spleen DCAF16 0.35 0.02 lasso 5 0.11 8.5e-04 -8.0 -9.3 1.4e-20 0.74 0.03 0.75 FALSE
15 GTEx Stomach DCAF16 0.21 0.04 lasso 6 0.02 5.6e-02 -8.2 -8.5 1.8e-17 0.91 0.02 0.92 FALSE
16 GTEx Thyroid DCAF16 0.11 0.02 lasso 5 0.03 2.3e-03 -8.0 -9.3 1.9e-20 0.79 0.03 0.95 FALSE
17 ROSMAP Brain Pre-frontal Cortex DCAF16 0.04 0.02 bslmm 379 0.01 3.9e-02 7.2 -7.8 4.8e-15 0.29 0.29 0.02 FALSE
18 YFS Blood DCAF16 0.02 0.02 lasso 1 0.01 1.1e-04 -8.3 -8.3 1.3e-16 0.83 0.06 0.93 FALSE
19 The Cancer Genome Atlas Colon Adenocarcinoma NCAPG 0.08 0.04 blup 34 0.09 1.1e-05 7.7 5.4 7.3e-08 0.01 0.32 0.48 FALSE
20 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma NCAPG 0.14 0.07 lasso 3 0.07 5.2e-08 7.2 6.9 6.9e-12 -0.18 0.88 0.11 FALSE
21 The Cancer Genome Atlas Brain Lower Grade Glioma DCAF16 0.09 0.02 lasso 3 0.04 5.2e-05 -8.3 -9.8 6.6e-23 0.72 0.00 0.99 FALSE
22 The Cancer Genome Atlas Brain Lower Grade Glioma NCAPG 0.02 0.03 lasso 1 0.02 9.0e-04 7.7 7.7 1.3e-14 -0.24 0.05 0.14 FALSE
23 The Cancer Genome Atlas Prostate Adenocarcinoma DCAF16 0.04 0.04 blup 31 0.04 2.2e-05 -8.0 -8.9 4.3e-19 0.73 0.00 0.99 FALSE
24 The Cancer Genome Atlas Thyroid Carcinoma DCAF16 0.07 0.04 blup 31 0.07 4.9e-07 -8.2 -10.0 2.1e-23 0.68 0.00 1.00 TRUE