Best TWAS P=9.82e-19 · Best GWAS P=1.27e-17 conditioned to 0.0973
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Mucosa | CPEB2 | 0.12 | 0.12 | lasso | 3 | 0.10 | 3.9e-07 | -7.7 | 7.8 | 8.0e-15 | -0.74 | 0.19 | 0.81 | FALSE |
| 2 | GTEx | Nerve Tibial | CPEB2 | 0.12 | 0.03 | lasso | 5 | 0.03 | 4.6e-03 | -8.5 | 8.8 | 9.8e-19 | -0.88 | 0.01 | 0.98 | TRUE |
| 3 | GTEx | Skin Sun Exposed Lower leg | RP11-665G4.1 | 0.09 | 0.11 | lasso | 1 | 0.09 | 5.0e-08 | -7.5 | 7.5 | 8.4e-14 | -0.70 | 0.73 | 0.27 | FALSE |
| 4 | NTR | Blood | CPEB2 | 0.03 | 0.03 | enet | 23 | 0.02 | 1.4e-08 | -6.9 | 6.7 | 1.6e-11 | -0.77 | 0.69 | 0.31 | FALSE |
| 5 | The Cancer Genome Atlas | Lung Adenocarcinoma | CPEB2 | 0.03 | 0.02 | enet | 6 | 0.01 | 7.2e-03 | -6.1 | -6.1 | 8.5e-10 | 0.69 | 0.05 | 0.24 | FALSE |