Best TWAS P=1.46e-07 · Best GWAS P=1.78e-07 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Whole Blood | MKNK1 | 0.14 | 0.15 | lasso | 1 | 0.14 | 1.2e-12 | -5.2 | -5.2 | 1.8e-07 | 1 | 0 | 1 | FALSE |
| 2 | GTEx | Whole Blood | MOB3C | 0.15 | 0.19 | lasso | 1 | 0.18 | 1.8e-16 | -5.2 | -5.2 | 1.8e-07 | 1 | 0 | 1 | FALSE |
| 3 | GTEx | Whole Blood | MKNK1-AS1 | 0.14 | 0.14 | lasso | 1 | 0.12 | 1.4e-11 | -5.2 | -5.2 | 1.8e-07 | 1 | 0 | 1 | FALSE |
| 4 | NTR | Blood | MKNK1 | 0.08 | 0.08 | lasso | 5 | 0.07 | 5.0e-23 | -5.2 | -5.3 | 1.5e-07 | 1 | 0 | 1 | TRUE |