[Hub]/) : Traits : Heel T-Score : ← →

chr1:40,748,755-42,406,344

Best TWAS P=1.21e-22 · Best GWAS P=2.37e-22 conditioned to 0.000309

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Aorta CTPS1 0.10 0.00 enet 8 0.00 4.6e-01 -8.21 -9.8 1.2e-22 0.75 0.05 0.60 TRUE
2 GTEx Artery Coronary CTPS1 0.25 -0.01 enet 23 0.00 3.0e-01 -2.14 -5.9 3.0e-09 0.39 0.07 0.14 FALSE
3 GTEx Breast Mammary Tissue (Female) CTPS1 0.12 -0.01 lasso 4 -0.01 7.5e-01 -7.84 -7.3 2.2e-13 0.61 0.04 0.10 FALSE
4 GTEx Cells EBV-transformed lymphocytes CTPS1 0.26 0.11 lasso 6 0.08 1.6e-03 -9.15 -8.4 3.2e-17 0.70 0.17 0.43 FALSE
5 GTEx Lung CTPS1 0.06 0.04 lasso 3 0.04 2.4e-04 -8.97 -9.5 3.2e-21 0.77 0.19 0.67 FALSE
6 GTEx Nerve Tibial SCMH1 0.16 0.03 enet 24 0.07 1.6e-05 -7.37 6.7 2.3e-11 -0.70 0.04 0.96 FALSE
7 GTEx Testis SLFNL1 0.30 0.17 lasso 14 0.28 5.3e-13 -9.42 -6.9 6.7e-12 0.85 0.01 0.99 FALSE
8 GTEx Testis CTPS1 0.57 0.28 enet 17 0.38 1.0e-17 2.51 -5.5 3.2e-08 0.48 0.98 0.02 FALSE
9 ROSMAP Brain Pre-frontal Cortex CTPS1 0.04 0.04 enet 7 0.04 9.1e-06 -7.85 -7.5 6.8e-14 0.59 0.59 0.17 FALSE
10 The Cancer Genome Atlas Brain Lower Grade Glioma SCMH1 0.04 0.01 enet 7 0.02 2.5e-03 -1.45 5.3 9.3e-08 -0.70 0.01 0.82 FALSE
11 The Cancer Genome Atlas Prostate Adenocarcinoma SCMH1 0.03 0.03 lasso 2 0.02 6.2e-03 -9.72 9.7 2.4e-22 -1.00 0.01 0.95 FALSE
12 The Cancer Genome Atlas Soft Tissue Sarcoma CTPS 0.06 0.00 blup 50 0.00 3.0e-01 -0.93 -5.5 5.1e-08 0.34 0.03 0.09 FALSE
13 The Cancer Genome Atlas Testicular Germ Cell Tumors SCMH1 0.35 0.14 blup 96 0.14 1.5e-05 4.10 -7.2 6.6e-13 0.47 0.18 0.25 FALSE
14 The Cancer Genome Atlas Thyroid Carcinoma SCMH1 0.07 0.08 blup 97 0.07 2.5e-07 -7.45 8.4 2.9e-17 -0.75 0.26 0.74 FALSE