[Hub]/) : Traits : Irritable Bowel Disease (IBD) :

chr22:29,304,253-31,118,395

Best TWAS P=9.49e-10 · Best GWAS P=8.36e-10 conditioned to 0.0683

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Esophagus Gastroesophageal Junction MTMR3 0.19 0.06 lasso 4 0.04 1.8e-02 -4.5 -5.8 7.2e-09 -0.56 0.07 0.27 FALSE
2 GTEx Pituitary NF2 0.25 0.01 lasso 7 0.08 4.4e-03 -4.4 5.5 3.1e-08 0.51 0.07 0.17 TRUE
3 GTEx Skin Sun Exposed Lower leg MTMR3 0.19 0.11 lasso 9 0.13 1.2e-10 -4.2 -5.9 3.3e-09 -0.59 0.63 0.37 FALSE
4 The Cancer Genome Atlas Stomach Adenocarcinoma MTMR3 0.07 0.02 blup 72 0.03 1.4e-03 -3.8 -5.8 6.1e-09 -0.22 0.03 0.05 FALSE
5 The Cancer Genome Atlas Thyroid Carcinoma MTMR3 0.21 0.08 blup 72 0.16 2.5e-15 5.7 -6.1 9.5e-10 -0.62 0.16 0.84 TRUE