Best TWAS P=9.49e-10 · Best GWAS P=8.36e-10 conditioned to 0.0683
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Gastroesophageal Junction | MTMR3 | 0.19 | 0.06 | lasso | 4 | 0.04 | 1.8e-02 | -4.5 | -5.8 | 7.2e-09 | -0.56 | 0.07 | 0.27 | FALSE |
| 2 | GTEx | Pituitary | NF2 | 0.25 | 0.01 | lasso | 7 | 0.08 | 4.4e-03 | -4.4 | 5.5 | 3.1e-08 | 0.51 | 0.07 | 0.17 | TRUE |
| 3 | GTEx | Skin Sun Exposed Lower leg | MTMR3 | 0.19 | 0.11 | lasso | 9 | 0.13 | 1.2e-10 | -4.2 | -5.9 | 3.3e-09 | -0.59 | 0.63 | 0.37 | FALSE |
| 4 | The Cancer Genome Atlas | Stomach Adenocarcinoma | MTMR3 | 0.07 | 0.02 | blup | 72 | 0.03 | 1.4e-03 | -3.8 | -5.8 | 6.1e-09 | -0.22 | 0.03 | 0.05 | FALSE |
| 5 | The Cancer Genome Atlas | Thyroid Carcinoma | MTMR3 | 0.21 | 0.08 | blup | 72 | 0.16 | 2.5e-15 | 5.7 | -6.1 | 9.5e-10 | -0.62 | 0.16 | 0.84 | TRUE |