Best TWAS P=3.14e-10 · Best GWAS P=8.41e-09 conditioned to 0.363
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Muscularis | LMOD1 | 0.16 | 0.09 | enet | 9 | 0.08 | 7.8e-06 | -5.7 | 5.6 | 2.3e-08 | -0.98 | 0.01 | 0.99 | FALSE |
| 2 | GTEx | Esophagus Muscularis | RP11-307B6.3 | 0.20 | 0.12 | lasso | 3 | 0.12 | 5.6e-08 | -5.7 | 5.6 | 2.8e-08 | -0.97 | 0.01 | 0.99 | FALSE |
| 3 | METSIM | Adipose | LMOD1 | 0.09 | 0.07 | bslmm | 496 | 0.07 | 4.8e-10 | -5.6 | 5.5 | 2.8e-08 | -0.97 | 0.01 | 0.99 | FALSE |
| 4 | The Cancer Genome Atlas | Cervical Squamous Cell Carcinoma | LMOD1 | 0.07 | 0.06 | blup | 59 | 0.03 | 2.1e-02 | -5.6 | 5.5 | 4.0e-08 | -0.90 | 0.01 | 0.84 | FALSE |
| 5 | The Cancer Genome Atlas | Lung Adenocarcinoma | LMOD1 | 0.04 | 0.01 | blup | 59 | 0.01 | 5.7e-02 | -5.6 | 6.3 | 3.1e-10 | -0.84 | 0.01 | 0.82 | TRUE |