Hub : Traits :

Intelligence (Savage-Jansen 2018)

2027 significantly associated models · 421 unique genes.

Significant Loci

#	chr	p0	p1	# assoc genes	# joint genes	best TWAS P	best SNP P	cond SNP P	% var exp	joint genes
1	1	22109370	22664774	2	1	1.9e-09	2.2e-09	9.2e-03	81	CDC42
2	1	28762508	30073828	2	1	7.5e-09	1.2e-07	4.0e-01	98	TMEM200B
3	1	31402148	32762733	1	1	1.3e-12	2.5e-12	1.0e+00	100	PEF1
4	1	40799427	42542658	2	2	8.9e-14	7.7e-16	2.8e-05	73	FOXO6 SCMH1
5	1	43152610	45153116	5	2	3.5e-10	1.6e-10	1.0e+00	100	HYI ST3GAL3
6	1	71163715	73435171	1	1	2.1e-24	1.6e-20	5.8e-08	66	NEGR1
7	1	109154974	110750277	6	1	2.2e-11	1.6e-10	3.8e-01	98	SYPL2
8	1	153241677	154638826	2	1	5.7e-08	3.5e-08	1.0e+00	100	RP11-422P24.10
9	1	171053153	172474017	1	1	8.7e-08	2.3e-07	5.4e-01	99	METTL13
10	1	173885712	175194390	1	1	5.2e-08	5.3e-08	2.3e-01	95	RABGAP1L
11	1	192845807	193470234	1	1	2.4e-07	9.4e-07	1.0e+00	100	CDC73
12	1	201164764	202607593	2	1	3.1e-10	8.4e-09	3.6e-01	98	LMOD1
13	2	23453834	24924438	1	1	7.1e-09	1.3e-08	3.5e-03	74	UBXN2A
14	2	70804467	72356449	1	1	1.8e-14	3.9e-14	1.0e+00	100	ZNF638
15	2	72774203	74654861	6	2	6.5e-11	3.7e-09	2.3e-01	96	FBXO41 TPRKB
16	2	99468341	101731705	3	2	2.4e-14	1.5e-15	7.2e-03	89	AFF3 CHST10
17	2	117979194	119470084	1	1	2.0e-09	6.9e-07	4.2e-01	97	CCDC93
18	2	161297929	162798581	2	1	4.6e-14	5.2e-13	1.0e+00	100	TANK
19	2	166020295	167506382	1	1	9.0e-09	3.1e-09	1.0e+00	100	TTC21B
20	3	23234618	24686628	4	1	3.3e-12	1.3e-16	6.9e-08	57	NKIRAS1
21	3	40537829	41986787	1	1	2.9e-07	1.2e-07	1.5e-01	93	CTNNB1
22	3	47911521	51298452	40	1	3.1e-32	3.7e-29	8.1e-01	100	RNF123
23	3	51616334	53778875	17	1	3.1e-12	3.5e-12	1.4e-01	95	NT5DC2
24	3	70757099	71880670	1	1	3.1e-09	3.9e-11	9.3e-05	65	FOXP1
25	3	93537290	94028192	2	1	3.1e-08	1.6e-06	2.5e-01	94	STX19
26	3	125733081	127373586	1	1	2.9e-07	5.4e-06	8.9e-06	5	CHCHD6
27	3	134986214	137253713	5	1	1.3e-09	1.3e-09	1.7e-06	38	STAG1
28	4	17104059	18507692	2	1	5.6e-13	5.6e-13	1.0e+00	100	NCAPG
29	4	105373669	107092169	2	1	1.6e-17	4.2e-23	4.4e-07	74	PPA2
30	4	151347355	153373680	6	1	6.9e-13	8.9e-13	8.1e-02	94	FAM160A1
31	5	65194584	67161259	2	1	1.3e-07	1.2e-07	1.0e+00	100	CD180
32	5	87104604	88677293	1	1	5.7e-08	2.8e-14	4.3e-09	40	LINC00461
33	5	92051598	93624507	2	1	1.2e-08	1.9e-10	5.6e-04	71	NR2F1-AS1
34	5	106016464	107704881	1	1	4.9e-09	5.7e-08	1.5e-05	37	EFNA5
35	5	138753725	141294691	22	1	3.0e-15	7.9e-12	1.3e-03	78	ZMAT2
36	5	176132977	177591495	3	1	3.6e-11	3.2e-11	1.0e+00	100	DBN1
37	6	10842333	12277622	1	1	1.2e-09	5.3e-10	4.9e-02	90	TMEM170B
38	6	13226792	14671877	1	1	5.9e-08	7.7e-08	5.5e-08	-2	RNF182
39	6	75766579	77324522	1	1	3.9e-08	3.9e-08	2.4e-01	95	MYO6
40	6	108183628	109704062	1	1	1.9e-12	7.9e-22	5.7e-11	53	FOXO3
41	6	154891396	156330580	1	1	4.7e-08	3.5e-07	2.1e-01	94	TFB1M
42	7	21336058	22188630	1	1	1.7e-07	1.1e-05	1.5e-01	90	DNAH11
43	7	43964217	45583220	3	2	1.6e-10	4.1e-11	2.3e-03	79	H2AFV OGDH
44	7	70546596	72313144	1	1	2.3e-14	2.2e-15	1.0e+00	100	CALN1
45	7	109603832	111895681	1	1	7.7e-08	2.3e-06	2.8e-01	95	IMMP2L
46	7	126529931	128425768	4	2	6.3e-15	2.3e-12	1.7e-01	96	SND1 ZNF800
47	7	132692468	133981227	1	1	2.2e-07	1.9e-14	1.6e-08	46	EXOC4
48	7	154046765	155442850	1	1	1.8e-07	9.6e-07	8.3e-01	100	RP11-5C23.1
49	8	30012514	31433801	1	1	7.6e-08	3.2e-09	2.6e-05	50	TEX15
50	8	65740418	67245848	4	1	1.1e-08	8.1e-08	9.6e-03	77	CTD-3025N20.3
51	8	92277765	93810859	1	1	2.4e-13	3.6e-14	2.0e-02	91	RUNX1T1
52	9	34382175	35776190	1	1	2.8e-07	3.6e-06	7.4e-01	100	FANCG
53	9	97966874	100366953	6	2	7.2e-09	2.0e-08	8.6e-01	100	AAED1 PTCH1
54	9	110932294	112391421	1	1	9.1e-08	1.3e-07	2.2e-01	95	IKBKAP
55	9	131169528	132601229	5	1	7.2e-10	9.7e-10	1.0e+00	100	IER5L
56	10	64195778	66034105	5	1	2.3e-11	2.9e-10	2.9e-01	97	NRBF2
57	10	73790819	74283057	1	1	4.9e-08	7.0e-07	1.9e-02	78	DDIT4
58	10	101291593	102725979	3	1	1.5e-09	5.2e-09	2.3e-02	85	CWF19L1
59	10	102853189	104956035	6	3	3.6e-13	1.9e-16	1.8e-02	92	GBF1 HPS6 NPM3
60	10	133089003	134482926	1	1	7.1e-08	1.3e-07	9.9e-04	61	BNIP3
61	11	605856	2029278	1	1	5.0e-08	8.0e-07	3.9e-03	66	TOLLIP
62	11	46543524	48559571	10	1	1.3e-09	2.6e-08	9.8e-01	100	MTCH2
63	11	56774260	58178587	2	1	6.9e-08	2.2e-07	1.8e-02	79	MED19
64	11	63295034	64687797	1	1	1.0e-07	4.8e-08	1.5e-02	80	TRPT1
65	11	73340690	73882260	1	1	1.1e-07	1.2e-04	3.4e-02	70	PAAF1
66	11	94805896	96276010	4	1	8.1e-09	1.2e-08	1.0e+00	100	MTMR2
67	12	48605088	50199949	4	1	8.6e-13	2.5e-14	1.1e-03	82	RP11-386G11.5
68	12	55694116	57125879	3	1	6.4e-08	1.6e-07	1.0e+00	100	RPS26
69	12	57249600	59046845	4	1	1.1e-11	8.9e-12	4.9e-03	83	TSPAN31
70	12	92920883	93568130	1	1	8.3e-08	3.1e-09	8.9e-06	44	EEA1
71	12	120215864	122150383	3	1	9.6e-08	3.9e-07	3.7e-02	83	RNF10
72	12	122713991	124591385	10	1	3.0e-09	3.1e-09	2.8e-01	97	ABCB9
73	14	26213713	27761335	1	1	1.2e-07	1.1e-09	3.0e-06	41	NOVA1
74	14	36802009	37298875	1	1	2.3e-07	1.5e-09	1.7e-03	73	NKX2-8
75	14	59246693	61035024	3	1	1.4e-08	1.5e-07	7.0e-02	88	CCDC175
76	14	101776302	102263464	1	1	1.3e-07	7.7e-06	8.2e-01	100	DIO3OS
77	14	103161201	104892153	11	8	8.7e-14	1.2e-13	1.0e+00	100	BAG5 CKB MARK3 RP11-73M18.6 RP11-73M18.8 ZFYVE21
78	15	51040798	52612484	2	1	2.9e-08	5.7e-11	6.1e-07	42	SCG3
79	15	63657737	64367745	1	1	2.1e-07	1.5e-07	1.0e+00	100	HERC1
80	15	81636267	84072745	8	1	3.8e-11	6.5e-10	3.2e-01	97	RP11-152F13.3
81	16	207611	1735921	2	1	6.2e-09	1.4e-06	2.0e-02	77	SOX8
82	16	11373301	13364255	1	2	2.7e-08	2.8e-10	4.4e-03	80	SNX29
83	16	27412414	30141258	27	1	8.1e-30	1.2e-24	8.4e-01	100	EIF3CL
84	16	52772129	54235440	2	1	8.2e-17	1.8e-14	7.5e-01	100	RBL2
85	16	67281662	68988905	5	1	2.1e-09	3.5e-08	7.8e-01	100	ESRP2
86	16	71070698	72657531	5	1	2.6e-10	3.8e-09	1.7e-01	95	ATXN1L
87	17	7816838	8315649	1	1	2.6e-07	1.6e-06	2.9e-03	61	VAMP2
88	17	27032827	29547601	4	1	1.4e-08	5.9e-08	1.4e-04	51	TAOK1
89	17	34146026	35675511	6	1	1.1e-10	6.8e-10	5.4e-01	99	GGNBP2
90	17	42814955	45597098	15	1	8.2e-11	1.7e-08	1.3e-01	93	ARL17B
91	17	55681549	57989860	11	1	8.9e-14	1.9e-13	1.0e+00	100	TRIM37
92	17	61008762	62461735	1	1	4.3e-08	1.4e-06	3.0e-02	80	MAP3K3
93	19	12215638	13611106	1	1	1.1e-07	1.9e-09	7.4e-09	7	CTD-2659N19.10
94	19	17963878	18640573	2	2	1.6e-09	5.9e-10	1.3e-01	94	JUND MAST3
95	19	36508392	37950253	1	1	5.9e-09	2.2e-05	7.4e-01	99	ZNF850
96	19	45569009	46073472	1	1	2.3e-07	1.8e-07	1.0e+00	100	CKM
97	19	46923752	48406374	2	2	2.3e-07	3.9e-08	2.2e-02	83	GRLF1 SAE1
98	19	58300066	59095126	1	1	5.9e-08	1.8e-09	6.0e-03	79	SLC27A5
99	20	33592248	35029669	3	1	5.6e-10	3.3e-08	5.8e-01	99	RBM39
100	20	46551079	48591758	7	2	1.3e-21	7.3e-17	5.1e-01	99	CSE1L PREX1
101	21	18271223	19680363	1	1	2.1e-07	7.1e-08	1.0e+00	100	BTG3
102	21	39849553	41419624	4	1	1.7e-11	6.6e-12	7.4e-02	93	HMGN1
103	22	30390990	32057501	5	1	3.6e-08	6.2e-08	1.0e+00	100	C22orf27
104	22	37394391	39042221	4	1	2.6e-08	4.2e-08	3.7e-03	72	ANKRD54
105	22	39064209	40571499	3	1	1.9e-13	2.5e-13	4.6e-04	77	MGAT3
106	22	40903421	43229137	14	2	9.2e-12	1.1e-09	4.1e-01	98	RP4-756G23.5 WBP2NL

Pleiotropic Associations

Trait	chisq ratio	# genes⁺	# genes⁺⁺	% genes⁺⁺	corr	corr P	genes
Verbal and Numeric Reasoning (VNR)	10.63	90	45	100.0	0.99	2.5e-85	AAED1 ABCB9 AFF3 ANKRD54 ARL17B ATXN1L BTG3 CALN1 CCDC93 CD180 CHCHD6 CHST10 CKB CKM CSE1L CWF19L1 DBN1 DIO3OS EEA1 EFNA5 EIF3CL EXOC4 FAM160A1 FANCG FBXO41 FOXO3 FOXO6 FOXP1 GBF1 GGNBP2 GRLF1 H2AFV HPS6 IKBKAP IMMP2L JUND LINC00461 LMOD1 MAP3K3 MED19 METTL13 MGAT3 MTCH2 MTMR2 NCAPG NEGR1 NKIRAS1 NKX2-8 NPM3 NR2F1-AS1 NRBF2 NT5DC2 PAAF1 PEF1 PPA2 PREX1 RBL2 RNF123 RP11-152F13.3 RP11-386G11.5 RP11-5C23.1 RP11-73M18.8 RP4-756G23.5 RPS26 RUNX1T1 SCG3 SCMH1 SLC27A5 SND1 SNX29 ST3GAL3 STAG1 SYPL2 TANK TEX15 TMEM170B TOLLIP TPRKB TRIM37 TRPT1 TSPAN31 TTC21B UBXN2A VAMP2 WBP2NL ZFYVE21 ZMAT2 ZNF638 ZNF800 ZNF850
Fluid intelligence score	9.28	61	28	62.2	0.99	1.3e-51	ABCB9 AFF3 ANKRD54 ARL17B ATXN1L BNIP3 BTG3 CALN1 CCDC93 CDC42 CHST10 CKB CSE1L CTD-3025N20.3 CWF19L1 EIF3CL FAM160A1 FBXO41 FOXO3 FOXO6 FOXP1 GGNBP2 H2AFV HPS6 IER5L IKBKAP LMOD1 MAP3K3 METTL13 MGAT3 MTCH2 MYO6 NCAPG NEGR1 NKIRAS1 NPM3 NR2F1-AS1 NRBF2 NT5DC2 PEF1 PPA2 PTCH1 RBL2 RBM39 RNF123 RP11-386G11.5 RP11-5C23.1 RP11-73M18.8 RPS26 ST3GAL3 STAG1 SYPL2 TANK TMEM170B TMEM200B TOLLIP TRIM37 TSPAN31 ZFYVE21 ZNF638 ZNF800
Qualifications: College or University degree	6.52	52	36	80.0	0.98	6.1e-37	ABCB9 AFF3 ARL17B BAG5 BNIP3 CALN1 CHST10 CKB CKM CSE1L CTD-3025N20.3 DBN1 DNAH11 EIF3CL FAM160A1 FBXO41 FOXO3 FOXO6 FOXP1 GBF1 H2AFV HPS6 HYI JUND LINC00461 MAST3 MTMR2 NEGR1 NKIRAS1 NOVA1 NPM3 NR2F1-AS1 NRBF2 PPA2 RBL2 RBM39 RNF10 RNF123 RP11-152F13.3 RP11-73M18.6 RP11-73M18.8 RPS26 SCMH1 SND1 SNX29 ST3GAL3 SYPL2 TANK TEX15 TRPT1 WBP2NL ZFYVE21
Qualifications: A levels/AS levels or equivalent	5.59	28	12	26.7	0.96	1.3e-16	ABCB9 ARL17B CHST10 CKB CKM CSE1L FAM160A1 FBXO41 FOXO6 GBF1 HYI JUND MAST3 MTMR2 NCAPG NEGR1 NPM3 NRBF2 PEF1 PPA2 RBL2 RNF123 RNF182 RPS26 SNX29 ST3GAL3 TANK ZFYVE21
Qualifications: None of the above	5.57	31	15	33.3	-0.96	5.5e-18	ABCB9 ATXN1L BNIP3 CHCHD6 CHST10 CKM CSE1L DBN1 DNAH11 EIF3CL FAM160A1 FOXO3 FOXP1 HPS6 HYI MTMR2 NEGR1 NPM3 NR2F1-AS1 NRBF2 PPA2 RBL2 RNF10 RNF123 RNF182 RPS26 SNX29 ST3GAL3 SYPL2 TANK TEX15
Qualifications: O levels/GCSEs or equivalent	3.69	5	2	4.4	0.91	2.9e-02	ABCB9 CSE1L MTMR2 RNF123 ST3GAL3
Qualifications: nursing, teaching	3.48	8	3	6.7	0.99	6.1e-06	ABCB9 LMOD1 NEGR1 PPA2 RNF123 RP11-73M18.6 RP11-73M18.8 ST3GAL3
Leg fat percentage (left)	3.11	20	14	31.1	-0.67	1.4e-03	AAED1 AFF3 BNIP3 CHST10 EIF3CL FOXO3 FOXP1 GGNBP2 JUND LINC00461 LMOD1 MAP3K3 MAST3 MTCH2 NCAPG NEGR1 PTCH1 RNF123 STX19 TEX15
BMI	3.04	34	23	51.1	-0.32	6.8e-02	AAED1 AFF3 ANKRD54 CCDC175 CDC73 CHST10 CKB CTNNB1 EIF3CL FOXO3 FOXP1 GGNBP2 H2AFV HMGN1 JUND LINC00461 LMOD1 MAP3K3 MAST3 MTCH2 NEGR1 NR2F1-AS1 NRBF2 NT5DC2 RABGAP1L RNF123 RPS26 SAE1 SCG3 STX19 SYPL2 TAOK1 TEX15 ZMAT2
Prospective memory result	3.04	3	0	0.0	0.00	1.0e+00	PEF1 RP11-152F13.3 ZNF638
Leg fat percentage (right)	3.04	20	13	28.9	-0.68	9.3e-04	AAED1 AFF3 ANKRD54 BNIP3 CHST10 EIF3CL FOXP1 GGNBP2 JUND LINC00461 LMOD1 MAP3K3 MAST3 MTCH2 NCAPG NEGR1 RNF123 STX19 TAOK1 TEX15
Sitting height	3.02	24	19	42.2	0.77	1.2e-05	AAED1 ABCB9 ARL17B CDC42 CSE1L CTNNB1 FOXO3 HERC1 MAP3K3 MARK3 MTCH2 MYO6 NCAPG PEF1 PPA2 PREX1 PTCH1 RBL2 RBM39 TFB1M TRIM37 TSPAN31 UBXN2A ZNF638
Arm fat percentage (right)	2.94	19	13	28.9	-0.59	7.6e-03	AFF3 CHST10 EIF3CL FOXO3 FOXP1 GGNBP2 JUND LINC00461 LMOD1 MAP3K3 MAST3 MTCH2 NCAPG NEGR1 PREX1 RNF123 SCG3 STX19 TEX15
Standing height	2.93	35	27	60.0	0.62	7.6e-05	AAED1 ABCB9 ARL17B ATXN1L CDC42 CKB CSE1L CTNNB1 CWF19L1 FAM160A1 FOXO3 H2AFV MAP3K3 MARK3 METTL13 MGAT3 MTCH2 MYO6 NCAPG NKIRAS1 NKX2-8 NRBF2 PEF1 PPA2 PREX1 PTCH1 RBL2 RBM39 RP11-73M18.8 STAG1 TFB1M TSPAN31 UBXN2A VAMP2 ZNF638
Arm fat percentage (left)	2.93	19	13	28.9	-0.62	4.7e-03	AFF3 CHST10 EIF3CL FOXP1 GGNBP2 HMGN1 JUND LINC00461 LMOD1 MAP3K3 MAST3 MTCH2 NCAPG NEGR1 PREX1 RNF123 SCG3 STX19 TEX15
Height	2.92	44	38	84.4	0.56	7.3e-05	AAED1 ABCB9 ANKRD54 ARL17B ATXN1L CCDC175 CDC42 CKB CSE1L CTNNB1 CWF19L1 FAM160A1 FOXO3 H2AFV HYI MAP3K3 MARK3 METTL13 MGAT3 MTCH2 MTMR2 MYO6 NCAPG NKIRAS1 NKX2-8 NRBF2 NT5DC2 PEF1 PPA2 PREX1 PTCH1 RBL2 RBM39 RP11-73M18.8 SCMH1 STAG1 TFB1M TOLLIP TRIM37 TSPAN31 UBXN2A VAMP2 ZFYVE21 ZNF638
Body fat percentage	2.90	16	12	26.7	-0.54	3.1e-02	CHST10 EIF3CL FOXO3 FOXP1 GGNBP2 JUND LINC00461 LMOD1 MAP3K3 MAST3 MTCH2 NEGR1 RNF123 SCG3 STX19 TEX15
Trunk fat-free mass	2.83	30	21	46.7	0.38	3.4e-02	AAED1 ABCB9 ATXN1L CKB CSE1L CTNNB1 CWF19L1 EIF3CL FAM160A1 FOXO3 LMOD1 MAP3K3 MARK3 MGAT3 MTCH2 MYO6 NCAPG PEF1 PPA2 PTCH1 RBL2 RBM39 RNF123 RPS26 SAE1 SYPL2 TFB1M UBXN2A ZMAT2 ZNF638
Trunk predicted mass	2.83	31	21	46.7	0.40	2.5e-02	AAED1 ABCB9 ATXN1L CKB CSE1L CTNNB1 CWF19L1 EIF3CL FAM160A1 FOXO3 LMOD1 MAP3K3 MARK3 MGAT3 MTCH2 MYO6 NCAPG NEGR1 PEF1 PPA2 PTCH1 RBL2 RBM39 RNF123 RPS26 SAE1 SYPL2 TFB1M UBXN2A ZMAT2 ZNF638
Body mass index (BMI)	2.82	21	13	28.9	-0.57	6.5e-03	AFF3 CHST10 CKB EIF3CL FOXO3 FOXP1 GGNBP2 HMGN1 LINC00461 LMOD1 MAP3K3 MAST3 MTCH2 NEGR1 NRBF2 RNF123 RPS26 SAE1 STAG1 STX19 TEX15
Leg fat mass (left)	2.79	20	14	31.1	-0.43	5.7e-02	AFF3 CHST10 EIF3CL FOXO3 FOXP1 GGNBP2 HMGN1 JUND LINC00461 LMOD1 MAST3 MTCH2 NEGR1 PEF1 RNF123 RPS26 SAE1 SCG3 STX19 TEX15
Leg fat mass (right)	2.76	21	13	28.9	-0.39	8.0e-02	AFF3 CHST10 CTNNB1 EIF3CL FOXO3 FOXP1 GGNBP2 HMGN1 JUND LINC00461 LMOD1 MAST3 MTCH2 NEGR1 PEF1 RNF123 RPS26 SAE1 SCG3 STX19 TEX15
Whole body water mass	2.71	30	23	51.1	0.36	4.9e-02	AAED1 ABCB9 ATXN1L CKB CSE1L CTNNB1 CWF19L1 EIF3CL FAM160A1 FOXO3 LINC00461 LMOD1 MAP3K3 MARK3 MGAT3 NCAPG NEGR1 PEF1 PPA2 PTCH1 RBL2 RBM39 RNF123 RPS26 SAE1 SYPL2 TFB1M UBXN2A ZMAT2 ZNF638
Arm fat mass (right)	2.70	21	13	28.9	-0.45	4.0e-02	AFF3 CHST10 CKB CTNNB1 EIF3CL FOXO3 FOXP1 GGNBP2 HMGN1 JUND LINC00461 LMOD1 MAST3 MTCH2 NEGR1 RNF123 RPS26 SAE1 SCG3 STX19 TEX15
Whole body fat-free mass	2.70	30	23	51.1	0.35	5.0e-02	AAED1 ABCB9 ATXN1L CKB CSE1L CTNNB1 CWF19L1 EIF3CL FAM160A1 FOXO3 LINC00461 LMOD1 MAP3K3 MARK3 MGAT3 NCAPG NEGR1 PEF1 PPA2 PTCH1 RBL2 RBM39 RNF123 RPS26 SAE1 SYPL2 TFB1M UBXN2A ZMAT2 ZNF638
Arm fat-free mass (right)	2.69	27	20	44.4	0.29	1.3e-01	AAED1 ABCB9 ATXN1L CKB CTNNB1 CWF19L1 EIF3CL FAM160A1 FOXO3 LINC00461 LMOD1 MAP3K3 MARK3 MGAT3 NCAPG NEGR1 PEF1 PPA2 PTCH1 RBL2 RBM39 RNF123 RPS26 SAE1 UBXN2A ZMAT2 ZNF638
Trunk fat percentage	2.68	18	13	28.9	-0.41	8.9e-02	ARL17B CHST10 CTNNB1 DIO3OS EIF3CL FOXO3 FOXP1 GGNBP2 JUND LINC00461 LMOD1 MAST3 MTCH2 NEGR1 RNF123 SCG3 STX19 TEX15
Arm predicted mass (right)	2.68	27	20	44.4	0.29	1.4e-01	AAED1 ABCB9 ATXN1L CKB CTNNB1 EIF3CL FAM160A1 FOXO3 GGNBP2 LINC00461 LMOD1 MAP3K3 MARK3 NCAPG NEGR1 PEF1 PPA2 PTCH1 RBL2 RBM39 RNF123 RPS26 SAE1 SYPL2 UBXN2A ZMAT2 ZNF638
Arm fat mass (left)	2.68	21	14	31.1	-0.45	4.1e-02	AFF3 CHST10 CKB CTNNB1 EIF3CL FOXO3 FOXP1 GGNBP2 HMGN1 JUND LINC00461 LMOD1 MAST3 MTCH2 NEGR1 RNF123 RPS26 SAE1 SCG3 STX19 TEX15
Whole body fat mass	2.66	19	13	28.9	-0.40	9.3e-02	CHST10 CKB CTNNB1 EIF3CL FOXO3 FOXP1 GGNBP2 HMGN1 JUND LINC00461 LMOD1 MAST3 MTCH2 NEGR1 RNF123 SAE1 SCG3 STX19 TEX15
Arm predicted mass (left)	2.62	28	20	44.4	0.28	1.6e-01	AAED1 ABCB9 ATXN1L CKB CTNNB1 CWF19L1 EIF3CL FAM160A1 FOXO3 GGNBP2 LINC00461 LMOD1 MAP3K3 MARK3 MGAT3 NCAPG NEGR1 PEF1 PPA2 PTCH1 RBL2 RBM39 RNF123 RPS26 SAE1 UBXN2A ZMAT2 ZNF638
Number of incorrect matches in round	2.61	4	1	2.2	-1.00	8.3e-04	CWF19L1 NPM3 PREX1 TMEM170B
Basal metabolic rate	2.61	27	24	53.3	0.31	1.2e-01	AAED1 ABCB9 ATXN1L CKB CTNNB1 EIF3CL FAM160A1 FOXO3 GGNBP2 LINC00461 LMOD1 MAP3K3 MARK3 NCAPG NEGR1 PEF1 PPA2 PTCH1 RBL2 RBM39 RNF123 RPS26 SAE1 SYPL2 UBXN2A ZMAT2 ZNF638
Arm fat-free mass (left)	2.60	27	20	44.4	0.31	1.2e-01	AAED1 ABCB9 ATXN1L CKB CTNNB1 EIF3CL FAM160A1 FOXO3 GGNBP2 LINC00461 LMOD1 MAP3K3 MARK3 MGAT3 NCAPG NEGR1 PEF1 PPA2 PTCH1 RBL2 RBM39 RNF123 RPS26 SAE1 UBXN2A ZMAT2 ZNF638
Forced vital capacity (FVC), Best measure	2.59	16	12	26.7	0.80	2.0e-04	AAED1 ARL17B CSE1L CTNNB1 FOXP1 MAP3K3 MTCH2 NCAPG PPA2 PREX1 PTCH1 RBL2 RNF123 UBXN2A ZMAT2 ZNF638
Blood Platelet Count	2.58	25	16	35.6	0.07	7.6e-01	AAED1 ABCB9 ATXN1L CKB CKM FAM160A1 FANCG H2AFV HMGN1 HYI LINC00461 MAP3K3 MED19 METTL13 MTCH2 NCAPG NRBF2 OGDH RP11-422P24.10 RP11-73M18.8 SLC27A5 SND1 TAOK1 TMEM170B TRPT1
Waist circumference	2.58	21	12	26.7	-0.37	9.8e-02	AFF3 CHST10 CKB CTNNB1 EIF3CL EXOC4 FOXO3 GGNBP2 JUND LINC00461 LMOD1 MAST3 MTCH2 NEGR1 RNF123 RPS26 SAE1 SCG3 STX19 TAOK1 TEX15
Forced vital capacity (FVC)	2.58	16	12	26.7	0.89	3.0e-06	AAED1 ARL17B CSE1L CTNNB1 FOXP1 MAP3K3 MTCH2 MYO6 NCAPG PPA2 PREX1 PTCH1 RBL2 RNF123 UBXN2A ZMAT2
Body Mass Index (BMI) (2010)	2.57	4	3	6.7	0.22	7.8e-01	EIF3CL MTCH2 NEGR1 SAE1
Noisy workplace	2.54	1	0	0.0	0.00	1.0e+00	H2AFV
Leg fat-free mass (right)	2.52	29	22	48.9	0.27	1.5e-01	AAED1 ABCB9 ATXN1L CKB CTNNB1 EIF3CL FAM160A1 FOXO3 GGNBP2 LINC00461 LMOD1 MAP3K3 MARK3 NCAPG NEGR1 PEF1 PPA2 PTCH1 RBL2 RBM39 RNF123 RPS26 SAE1 STX19 SYPL2 TFB1M UBXN2A ZMAT2 ZNF638
Leg predicted mass (right)	2.52	28	22	48.9	0.29	1.3e-01	AAED1 ABCB9 ATXN1L CKB CTNNB1 EIF3CL FAM160A1 FOXO3 GGNBP2 LINC00461 LMOD1 MAP3K3 MARK3 NCAPG NEGR1 PEF1 PPA2 PTCH1 RBL2 RBM39 RNF123 RPS26 SAE1 SYPL2 TFB1M UBXN2A ZMAT2 ZNF638
Age at First Birth	2.51	3	2	4.4	0.00	1.0e+00	CHST10 RNF123 RP11-422P24.10
Leg fat-free mass (left)	2.51	28	21	46.7	0.31	1.0e-01	AAED1 ABCB9 CDC42 CKB CTNNB1 EIF3CL FAM160A1 FOXO3 GGNBP2 LINC00461 LMOD1 MAP3K3 MARK3 NCAPG NEGR1 PEF1 PPA2 PTCH1 RBL2 RBM39 RNF123 RPS26 SAE1 STX19 SYPL2 UBXN2A ZMAT2 ZNF638
Trunk fat mass	2.51	19	13	28.9	-0.41	8.3e-02	ARL17B CHST10 CKB CTNNB1 EIF3CL FOXO3 FOXP1 GGNBP2 HMGN1 JUND LINC00461 LMOD1 MAST3 MTCH2 NEGR1 RNF123 SCG3 STX19 TEX15
Leg predicted mass (left)	2.50	28	21	46.7	0.31	1.0e-01	AAED1 ABCB9 CDC42 CKB CTNNB1 EIF3CL FAM160A1 FOXO3 GGNBP2 LINC00461 LMOD1 MAP3K3 MARK3 NCAPG NEGR1 PEF1 PPA2 PTCH1 RBL2 RBM39 RNF123 RPS26 SAE1 STX19 SYPL2 UBXN2A ZMAT2 ZNF638
Major Depression (MDD)	2.49	4	1	2.2	0.98	1.7e-02	BAG5 NEGR1 RP11-73M18.6 ZFYVE21
Weight	2.48	23	18	40.0	-0.02	9.3e-01	ATXN1L CKB CTNNB1 EIF3CL FOXO3 GGNBP2 LINC00461 LMOD1 MAST3 NCAPG NEGR1 PEF1 PPA2 RBL2 RBM39 RNF123 RPS26 SAE1 SCG3 STX19 TEX15 ZMAT2 ZNF638
Comparative height size at age 10	2.46	28	21	46.7	0.41	3.1e-02	AAED1 ABCB9 ARL17B ATXN1L CKB CSE1L CTNNB1 EIF3CL FAM160A1 FOXO3 HYI JUND MAP3K3 MARK3 METTL13 MTCH2 NCAPG PPA2 PREX1 PTCH1 RBL2 RBM39 RP11-73M18.8 STAG1 TFB1M UBXN2A ZFYVE21 ZNF638
Overall health rating	2.45	9	6	13.3	-0.97	1.2e-05	ATXN1L CKM FOXP1 LMOD1 RBL2 RNF123 TANK TEX15 VAMP2
Alcohol usually taken with meals	2.43	6	2	4.4	0.97	9.5e-04	CHST10 FOXP1 HYI NEGR1 NRBF2 RABGAP1L
Fed-up feelings	2.40	3	2	4.4	0.00	1.0e+00	LINC00461 RNF123 STAG1
Forced expiratory volume in 1-second (FEV1)	2.37	13	9	20.0	0.81	8.1e-04	AAED1 ARL17B CSE1L CTNNB1 FOXP1 MAP3K3 MTCH2 NCAPG PPA2 PREX1 RNF123 RPS26 UBXN2A
Forced expiratory volume in 1-second (FEV1), Best measure	2.35	13	9	20.0	0.77	2.2e-03	ARL17B CSE1L CTNNB1 FOXP1 MAP3K3 MTCH2 NCAPG PPA2 PREX1 RNF123 RPS26 UBXN2A ZMAT2
Age at first live birth	2.29	3	1	2.2	0.00	1.0e+00	NCAPG RNF123 RPS26
Depressed Affect (Nagel 2018)	2.28	6	4	8.9	-0.48	3.3e-01	ARL17B LINC00461 MTCH2 RNF123 STAG1 TANK
Neuroticism (Nagel 2018)	2.24	7	4	8.9	-0.51	2.4e-01	ARL17B BTG3 LINC00461 MTCH2 NT5DC2 RP4-756G23.5 STAG1
Average weekly red wine intake	2.22	3	1	2.2	0.00	1.0e+00	ABCB9 FOXP1 MTMR2
Neuroticism	2.18	10	3	6.7	-0.61	6.0e-02	ARL17B BTG3 LINC00461 METTL13 MTCH2 NT5DC2 RABGAP1L RNF123 RP4-756G23.5 STAG1
Schizophrenia (2018)	2.17	5	1	2.2	-0.22	7.2e-01	ABCB9 MGAT3 RP11-73M18.8 ZFYVE21 ZMAT2
Hip circumference	2.17	16	11	24.4	-0.04	8.7e-01	CTNNB1 EIF3CL FOXO3 GGNBP2 HMGN1 LINC00461 LMOD1 MAST3 MTCH2 NEGR1 PEF1 RBL2 RBM39 RNF123 SAE1 ZMAT2
Seen doctor (GP) for nerves, anxiety, tension or depression	2.17	3	1	2.2	0.00	1.0e+00	NEGR1 RP11-73M18.8 ZFYVE21
Bipolar Disorder (2011)	2.16	1	1	2.2	0.00	1.0e+00	RP11-386G11.5
Seen a psychiatrist for nerves, anxiety, tension or depression	2.15	4	0	0.0	1.00	1.3e-03	BAG5 MARK3 RP11-73M18.8 ZFYVE21
Commuting to job workplace: Public transport	2.13	2	0	0.0	0.00	1.0e+00	CHST10 RP11-152F13.3
Age when periods started (menarche)	2.11	11	6	13.3	-0.10	7.7e-01	C22orf27 FOXO3 HMGN1 HYI MAST3 MTCH2 NEGR1 NRBF2 NT5DC2 RNF123 SLC27A5
Frequency of tiredness / lethargy in last 2 weeks	2.11	3	0	0.0	0.00	1.0e+00	CSE1L SCG3 STAG1
Friendships satisfaction	2.11	3	0	0.0	0.00	1.0e+00	GBF1 MTMR2 ZMAT2
Number of treatments/medications taken	2.10	5	1	2.2	-0.99	1.9e-03	FBXO41 NCAPG RABGAP1L RNF123 TANK
Average weekly beer plus cider intake	2.08	3	0	0.0	0.00	1.0e+00	NRBF2 RNF10 RNF123
Schizophrenia (2014)	2.06	5	2	4.4	-0.25	6.8e-01	ABCB9 MGAT3 NT5DC2 RP11-73M18.8 ZFYVE21
Neuroticism score	2.05	6	3	6.7	-0.41	4.2e-01	ARL17B LINC00461 MTCH2 RABGAP1L RNF123 STAG1
Depression (Nagel 2018)	2.04	1	1	2.2	0.00	1.0e+00	STAG1
Maternal smoking around birth	2.04	3	1	2.2	0.00	1.0e+00	CKM GGNBP2 RUNX1T1
Alcohol intake frequency.	2.04	9	3	6.7	-0.45	2.3e-01	BNIP3 EIF3CL FOXP1 H2AFV MTCH2 PPA2 RNF123 TEX15 UBXN2A
Mood swings	2.02	2	2	4.4	0.00	1.0e+00	ARL17B RNF123
Bipolar Disorder or Schizophrenia	2.01	7	5	11.1	-0.29	5.3e-01	ABCB9 CWF19L1 NT5DC2 RP11-73M18.8 TRPT1 ZFYVE21 ZMAT2
Smoking Status	2.00	8	2	4.4	-0.53	1.7e-01	CKM CTD-3025N20.3 FOXP1 MTCH2 RNF10 RP11-152F13.3 RPS26 TANK
Worry (Nagel 2018)	1.99	6	3	6.7	-0.75	8.3e-02	ARL17B MTCH2 NT5DC2 RABGAP1L RP4-756G23.5 STAG1
Hand grip strength (left)	1.99	9	4	8.9	0.28	4.7e-01	ARL17B CALN1 FOXP1 GBF1 MTCH2 NCAPG NPM3 PEF1 TFB1M
Current tobacco smoking	1.99	2	0	0.0	0.00	1.0e+00	DDIT4 MTCH2
Irritability	1.98	3	1	2.2	0.00	1.0e+00	ARL17B LINC00461 ZFYVE21
Frequency of unenthusiasm / disinterest in last 2 weeks	1.97	1	0	0.0	0.00	1.0e+00	STAG1
Comparative body size at age 10	1.97	6	5	11.1	0.11	8.3e-01	EIF3CL GGNBP2 MTCH2 NEGR1 RP11-386G11.5 SAE1
Pain experienced in last month	1.96	4	1	2.2	0.95	4.9e-02	ATXN1L RABGAP1L RNF123 RPS26
Reaction Time	1.94	4	4	8.9	-0.63	3.7e-01	ARL17B FOXO3 RP11-386G11.5 ZNF638
Impedance of arm (right)	1.94	15	11	24.4	0.03	9.3e-01	ARL17B ESRP2 FOXO3 JUND LMOD1 NEGR1 NRBF2 NT5DC2 PEF1 RNF123 RPS26 SAE1 SOX8 STAG1 SYPL2
Mean time to correctly identify matches	1.94	4	2	4.4	-0.58	4.2e-01	ARL17B FOXO3 RP11-386G11.5 ZNF638
Worrier / anxious feelings	1.93	5	3	6.7	-0.99	9.0e-04	ARL17B NT5DC2 RP4-756G23.5 SND1 STAG1
Smoking status: Current	1.93	2	0	0.0	0.00	1.0e+00	DDIT4 MTCH2
Medication for pain relief, constipation, heartburn	1.91	2	1	2.2	0.00	1.0e+00	LMOD1 RABGAP1L
Forced expiratory volume in 1-second (FEV1), predicted	1.91	6	3	6.7	0.64	1.7e-01	CDC42 MAP3K3 MTCH2 NCAPG PTCH1 ZNF638
Schizophrenia vs Biploar Disorder	1.90	1	0	0.0	0.00	1.0e+00	CSE1L
Impedance of arm (left)	1.90	16	10	22.2	0.07	8.0e-01	ARL17B ESRP2 FOXO3 GGNBP2 IER5L LMOD1 NEGR1 NRBF2 NT5DC2 PEF1 RNF123 RPS26 SAE1 SOX8 STAG1 SYPL2
Worry too long after embarrassment	1.90	5	1	2.2	0.45	4.5e-01	ARL17B DBN1 MGAT3 PPA2 STAG1
Hand grip strength (right)	1.89	10	2	4.4	0.65	4.2e-02	AAED1 ARL17B EIF3CL GBF1 MTCH2 NCAPG NPM3 PEF1 RBM39 TFB1M
Medication: Paracetamol	1.89	2	1	2.2	0.00	1.0e+00	ARL17B RABGAP1L
Wheeze or whistling in the chest in last year	1.87	2	1	2.2	0.00	1.0e+00	AFF3 RNF123
Miserableness	1.87	3	2	4.4	0.00	1.0e+00	MTCH2 RNF123 STAG1
Lung FEV1/FVC ratio	1.85	17	10	22.2	0.02	9.5e-01	BTG3 CDC42 CTNNB1 ESRP2 FOXO3 HERC1 IER5L LMOD1 MAP3K3 NEGR1 NKX2-8 NRBF2 PEF1 PPA2 PTCH1 RPS26 TAOK1
Medication: Paracetamol	1.85	2	1	2.2	0.00	1.0e+00	ARL17B RABGAP1L
Ever depressed for a whole week	1.84	2	0	0.0	0.00	1.0e+00	CSE1L RP11-73M18.8
Pack years adult smoking proportion	1.83	1	0	0.0	0.00	1.0e+00	BNIP3
Past tobacco smoking	1.80	2	0	0.0	0.00	1.0e+00	TANK VAMP2
HDL Cholesterol	1.78	2	2	4.4	0.00	1.0e+00	ESRP2 MTCH2
Neuroticism (2016)	1.77	3	0	0.0	0.00	1.0e+00	ARL17B LINC00461 TANK
Impedance of whole body	1.77	17	13	28.9	-0.05	8.5e-01	ARL17B CKB ESRP2 FOXO3 GGNBP2 JUND LINC00461 LMOD1 NEGR1 NRBF2 NT5DC2 RBM39 RNF123 RPS26 SAE1 STAG1 SYPL2
Chronotype (morning person)	1.76	4	2	4.4	-0.53	4.7e-01	DBN1 IER5L MTCH2 TRIM37
Taking other prescription medications	1.76	1	1	2.2	0.00	1.0e+00	RNF123
Suffer from 'nerves'	1.76	2	2	4.4	0.00	1.0e+00	EIF3CL MTCH2
Long-standing illness, disability or infirmity	1.76	3	0	0.0	0.00	1.0e+00	NEGR1 NR2F1-AS1 RP11-73M18.8
Alcohol intake versus 10 years previously	1.75	2	1	2.2	0.00	1.0e+00	NEGR1 RNF123
Sensitivity / hurt feelings	1.74	2	1	2.2	0.00	1.0e+00	ARL17B STAG1
Neck or shoulder pain in last month	1.74	2	1	2.2	0.00	1.0e+00	ATXN1L RPS26
Ever smoked	1.74	2	0	0.0	0.00	1.0e+00	GRLF1 VAMP2
Lung FVC	1.73	18	11	24.4	0.08	7.7e-01	ABCB9 ARL17B BTG3 EIF3CL FOXO3 FOXO6 FOXP1 NCAPG NR2F1-AS1 NRBF2 RBM39 RNF123 RP11-152F13.3 RP4-756G23.5 RPS26 TFB1M UBXN2A ZMAT2
Number of self-reported non-cancer illnesses	1.73	2	1	2.2	0.00	1.0e+00	FBXO41 NEGR1
Guilty feelings	1.73	2	0	0.0	0.00	1.0e+00	MGAT3 UBXN2A
Diastolic blood pressure, automated reading	1.73	11	7	15.6	-0.53	9.4e-02	ABCB9 CTNNB1 FBXO41 HYI LINC00461 LMOD1 MAST3 NCAPG NRBF2 RNF123 TPRKB
Headache pain in last month	1.72	3	1	2.2	0.00	1.0e+00	ARL17B NT5DC2 RPS26
Age at last live birth	1.71	1	1	2.2	0.00	1.0e+00	RNF123
Tense / 'highly strung'	1.70	2	1	2.2	0.00	1.0e+00	ARL17B RABGAP1L
Risk taking	1.70	2	0	0.0	0.00	1.0e+00	FAM160A1 SND1
Frequency of depressed mood in last 2 weeks	1.68	3	1	2.2	0.00	1.0e+00	ARL17B CSE1L STAG1
Peak expiratory flow (PEF)	1.68	8	2	4.4	0.83	1.1e-02	ARL17B FOXO3 MTCH2 NCAPG NR2F1-AS1 PEF1 RBM39 UBXN2A
Systolic Blood Pressure	1.67	17	11	24.4	-0.20	4.3e-01	ANKRD54 ARL17B ATXN1L CKB FBXO41 FOXO3 HYI IER5L MED19 NCAPG PREX1 RNF123 SCMH1 SND1 TOLLIP VAMP2 ZMAT2
Frequency of tenseness / restlessness in last 2 weeks	1.67	2	2	4.4	0.00	1.0e+00	ARL17B STAG1
Commuting to job workplace: Cycle	1.67	1	0	0.0	0.00	1.0e+00	NCAPG
Impedance of leg (right)	1.66	17	12	26.7	-0.25	3.3e-01	CKB EIF3CL ESRP2 FAM160A1 IKBKAP LINC00461 LMOD1 MTMR2 NEGR1 NT5DC2 RBL2 RBM39 RNF123 RP11-386G11.5 RPS26 SAE1 SYPL2
Blood White Count	1.65	21	13	28.9	-0.27	2.3e-01	AAED1 BAG5 CKB CKM FAM160A1 H2AFV MAP3K3 MARK3 MGAT3 MTCH2 NCAPG NRBF2 RNF123 RP11-73M18.8 SAE1 TAOK1 TEX15 UBXN2A VAMP2 ZFYVE21 ZNF638
Hearing difficulty/problems with background noise	1.65	2	1	2.2	0.00	1.0e+00	ARL17B DIO3OS
Impedance of leg (left)	1.64	16	11	24.4	-0.24	3.8e-01	CKB EIF3CL ESRP2 FAM160A1 IKBKAP LINC00461 LMOD1 NEGR1 NT5DC2 RBL2 RBM39 RNF123 RP11-386G11.5 RPS26 SAE1 SYPL2
Number of live births	1.64	1	0	0.0	0.00	1.0e+00	VAMP2
Loneliness, isolation	1.64	2	2	4.4	0.00	1.0e+00	CSE1L MTCH2
Systolic blood pressure, automated reading	1.63	6	1	2.2	0.08	8.8e-01	ARL17B FBXO41 HYI NCAPG PPA2 RNF123
Medication for cholesterol	1.63	1	0	0.0	0.00	1.0e+00	RBL2
Allergy	1.62	5	2	4.4	-0.37	5.4e-01	ABCB9 HMGN1 RP11-422P24.10 RPS26 TTC21B
Respiratory disease	1.61	4	1	2.2	0.80	2.0e-01	HMGN1 IER5L RPS26 ZMAT2
Knee pain experienced in last month	1.60	1	0	0.0	0.00	1.0e+00	RABGAP1L
Unable to work because of sickness or disability	1.60	1	0	0.0	0.00	1.0e+00	VAMP2
Heel T-Score	1.59	17	14	31.1	-0.34	1.8e-01	ABCB9 ANKRD54 ARL17B BAG5 CKB CTNNB1 CWF19L1 EEA1 NCAPG NEGR1 PTCH1 RNF123 RP11-73M18.6 RP11-73M18.8 SLC27A5 TAOK1 ZNF638
Reason for reducing amount of alcohol drunk: Health precaution	1.58	1	0	0.0	0.00	1.0e+00	STX19
Ever unenthusiastic/disinterested for a whole week	1.57	1	1	2.2	0.00	1.0e+00	ZMAT2
Illnesses of siblings	1.57	1	1	2.2	0.00	1.0e+00	RBL2
Nervous feelings	1.56	3	1	2.2	0.00	1.0e+00	ARL17B NT5DC2 STAG1
Health satisfaction	1.55	1	1	2.2	0.00	1.0e+00	LMOD1
Hayfever/allergic rhinitis (self-reported)	1.54	1	0	0.0	0.00	1.0e+00	RPS26
Asthma (self-reported)	1.54	1	1	2.2	0.00	1.0e+00	RPS26
Mouth/teeth dental problems: Dentures	1.53	3	0	0.0	0.00	1.0e+00	HERC1 RNF123 STAG1
Asthma	1.53	2	1	2.2	0.00	1.0e+00	AFF3 RPS26
Financial situation satisfaction	1.53	1	0	0.0	0.00	1.0e+00	RNF123
Hypothyroidism (self reported)	1.52	3	3	6.7	0.00	1.0e+00	JUND RPS26 TANK
Pulse rate, automated reading	1.52	10	3	6.7	0.04	9.2e-01	AAED1 CTNNB1 HERC1 HYI LINC00461 LMOD1 NEGR1 RBL2 RNF123 TRPT1
Cholesterol lowering medication	1.52	1	0	0.0	0.00	1.0e+00	NCAPG
Vascular/heart problems diagnosed by doctor	1.51	5	1	2.2	0.84	7.8e-02	FBXO41 NCAPG NEGR1 RBL2 TEX15
Allergy or Eczema	1.50	5	2	4.4	0.58	3.1e-01	ABCB9 EIF3CL GGNBP2 NEGR1 RPS26
Cardiovascular Disease	1.49	7	3	6.7	-0.17	7.1e-01	ATXN1L CDC73 FBXO41 NCAPG NEGR1 RBL2 TEX15
Father's age at death	1.48	1	0	0.0	0.00	1.0e+00	RNF123
High blood pressure	1.47	6	1	2.2	0.26	6.2e-01	FBXO41 NCAPG NEGR1 NRBF2 RBL2 TEX15
Birth weight of first child	1.47	3	1	2.2	0.00	1.0e+00	PPA2 PREX1 RPS26
Diabetes (self-reported)	1.45	1	0	0.0	0.00	1.0e+00	RBL2
Medication: Ventolin 100micrograms inhaler	1.45	1	0	0.0	0.00	1.0e+00	RPS26
Handedness (chirality/laterality): Left-handed	1.45	1	1	2.2	0.00	1.0e+00	ARL17B
Hair/balding pattern: Pattern 4	1.44	3	2	4.4	0.00	1.0e+00	ARL17B CTNNB1 RP11-422P24.10
Type 2 Diabetes (T2D) (2018)	1.43	1	0	0.0	0.00	1.0e+00	RBL2
Relative age of first facial hair	1.42	4	1	2.2	0.21	7.9e-01	ARL17B FOXO3 HMGN1 SLC27A5
Mouth/teeth dental problems: Mouth ulcers	1.42	2	0	0.0	0.00	1.0e+00	ARL17B MTMR2
Hayfever, allergic rhinitis or eczema	1.41	3	1	2.2	0.00	1.0e+00	ABCB9 GGNBP2 RPS26
Leg pain on walking	1.41	1	0	0.0	0.00	1.0e+00	RNF123
Hypertension (Self-reported)	1.41	6	1	2.2	-0.54	2.7e-01	FBXO41 NCAPG NEGR1 NRBF2 RBL2 TEX15
Number of operations (self-reported)	1.41	1	1	2.2	0.00	1.0e+00	PPA2
Diabetes diagnosed by doctor	1.40	1	0	0.0	0.00	1.0e+00	RBL2
Supplements: Zinc	1.39	1	0	0.0	0.00	1.0e+00	NRBF2
Relative age voice broke	1.39	3	0	0.0	0.00	1.0e+00	ARL17B FOXO3 HMGN1
Had other major operations	1.39	1	0	0.0	0.00	1.0e+00	PPA2
Blood Red Count	1.38	28	17	37.8	-0.17	3.8e-01	AFF3 ARL17B CHST10 CKB CKM CSE1L CTD-2659N19.10 EIF3CL ESRP2 H2AFV HYI IER5L LINC00461 MARK3 MED19 MTMR2 NRBF2 NT5DC2 OGDH PREX1 RABGAP1L RNF10 RNF123 RP11-73M18.8 RPS26 SAE1 TAOK1 ZFYVE21
Medication: Levothyroxine sodium	1.38	2	1	2.2	0.00	1.0e+00	RPS26 SAE1
Hypothyroidism/myxoedema (self-reported)	1.38	3	1	2.2	0.00	1.0e+00	JUND RPS26 TANK
Prostate Cancer	1.37	2	1	2.2	0.00	1.0e+00	RNF123 RP11-422P24.10
Pulse rate	1.36	2	0	0.0	0.00	1.0e+00	CTNNB1 RBL2
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.36	1	1	2.2	0.00	1.0e+00	ARL17B
Birth weight	1.35	5	1	2.2	0.52	3.7e-01	MTCH2 NCAPG PREX1 SND1 UBXN2A
Crohns Disease (2012)	1.34	2	2	4.4	0.00	1.0e+00	EIF3CL RNF123
LDL Cholesterol	1.34	1	1	2.2	0.00	1.0e+00	SYPL2
Medication: Seretide 50 evohaler	1.31	1	0	0.0	0.00	1.0e+00	RNF123
Waist Hip Ratio (WHR)	1.30	8	5	11.1	-0.48	2.3e-01	ABCB9 HERC1 JUND MAST3 NT5DC2 OGDH RBL2 STAG1
Ulcerative Colitis (UC)	1.29	2	1	2.2	0.00	1.0e+00	EIF3CL RNF123
Exposure to tobacco smoke at home	1.28	1	0	0.0	0.00	1.0e+00	RNF123
Medication: Blood pressure	1.28	1	0	0.0	0.00	1.0e+00	FBXO41
Irritable Bowel Disease (IBD)	1.27	2	2	4.4	0.00	1.0e+00	EIF3CL RNF123
Illnesses of mother	1.27	1	0	0.0	0.00	1.0e+00	GGNBP2
Medication: Co-codamol	1.26	1	0	0.0	0.00	1.0e+00	RNF123
Heel bone mineral density (BMD) T-score, automated (left)	1.26	2	1	2.2	0.00	1.0e+00	CKB PTCH1
Hair/balding pattern: Pattern 3	1.26	1	1	2.2	0.00	1.0e+00	ARL17B
Crohns Disease (2017)	1.25	2	2	4.4	0.00	1.0e+00	EIF3CL RNF123
Breast Cancer	1.25	2	0	0.0	0.00	1.0e+00	NKX2-8 RNF123
Heel bone mineral density (BMD) T-score, automated (right)	1.21	4	1	2.2	-0.99	1.1e-02	CKB NCAPG PTCH1 RP11-73M18.8
Ulcerative Colitis	1.16	1	1	2.2	0.00	1.0e+00	RNF123
Medication: Bendroflumethiazide	1.16	1	1	2.2	0.00	1.0e+00	TEX15
Triglycerides	1.06	2	1	2.2	0.00	1.0e+00	NRBF2 SAE1
Hair/balding pattern: Pattern 2	0.88	1	1	2.2	0.00	1.0e+00	ARL17B
Blood Eosinophil Count	0.87	9	7	15.6	0.31	4.2e-01	ABCB9 ARL17B CKM ESRP2 FANCG MAST3 MED19 OGDH RPS26
Tanning	0.35	3	2	4.4	0.00	1.0e+00	ATXN1L RBM39 RP11-152F13.3
Hair Pigment	0.21	10	6	13.3	-0.34	3.4e-01	ABCB9 CKB DDIT4 FOXO3 MTCH2 RBM39 RP11-152F13.3 RP11-386G11.5 RP4-756G23.5 RPS26

Associations by panel

study	tissue	# hits	% hits/tests	avg chisq
GTEx	Vagina	8	1.26	3.9
GTEx	Esophagus Gastroesophageal Junction	27	1.87	3.6
GTEx	Ovary	13	1.43	3.6
GTEx	Brain Cortex	16	1.55	3.5
GTEx	Brain Frontal Cortex BA9	9	0.97	3.5
GTEx	Brain Putamen basal ganglia	7	1.12	3.5
GTEx	Colon Sigmoid	23	1.57	3.5
GTEx	Stomach	23	1.58	3.5
GTEx	Breast Mammary Tissue	33	1.67	3.4
GTEx	Cells EBV-transformed lymphocytes	24	1.69	3.4
GTEx	Colon Transverse	28	1.36	3.4
GTEx	Esophagus Mucosa	49	1.48	3.4
GTEx	Esophagus Muscularis	50	1.55	3.4
GTEx	Heart Atrial Appendage	29	1.84	3.4
GTEx	Liver	12	1.68	3.4
GTEx	Small Intestine Terminal Ileum	4	0.87	3.4
GTEx	Spleen	18	1.28	3.4
GTEx	Artery Aorta	51	1.71	3.3
GTEx	Artery Coronary	18	1.52	3.3
GTEx	Artery Tibial	57	1.52	3.3
GTEx	Brain Cerebellar Hemisphere	18	1.21	3.3
GTEx	Brain Nucleus accumbens basal ganglia	11	1.27	3.3
GTEx	Breast Mammary Tissue (Female)	27	1.64	3.3
GTEx	Heart Left Ventricle	28	1.83	3.3
GTEx	Lung	43	1.50	3.3
GTEx	Muscle Skeletal	45	1.56	3.3
GTEx	Skin Not Sun Exposed Suprapubic	29	1.18	3.3
GTEx	Skin Sun Exposed Lower leg	49	1.35	3.3
GTEx	Uterus	9	1.58	3.3
The Cancer Genome Atlas	Glioblastoma Multiforme	17	1.67	3.3
The Cancer Genome Atlas	Skin Cutaneous Melanoma	7	1.32	3.3
GTEx	Adipose Subcutaneous	45	1.29	3.2
GTEx	Adipose Visceral Omentum	29	1.42	3.2
GTEx	Brain Cerebellum	27	1.36	3.2
GTEx	Brain Hippocampus	8	1.53	3.2
GTEx	Brain Hypothalamus	5	0.85	3.2
GTEx	Breast Mammary Tissue (Male)	13	1.09	3.2
GTEx	Nerve Tibial	64	1.48	3.2
GTEx	Pancreas	21	1.29	3.2
GTEx	Pituitary	18	1.62	3.2
GTEx	Prostate	8	0.96	3.2
GTEx	Brain Caudate basal ganglia	12	1.30	3.1
GTEx	Cells Transformed fibroblasts	61	1.45	3.1
GTEx	Testis	33	1.05	3.1
GTEx	Whole Blood	24	1.20	3.1
ROSMAP	Brain Pre-frontal Cortex	53	1.21	3.1
The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	12	1.09	3.1
The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	28	1.77	3.1
The Cancer Genome Atlas	Stomach Adenocarcinoma	20	1.19	3.1
GTEx	Thyroid	47	1.18	3.0
The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	26	1.27	3.0
The Cancer Genome Atlas	Brain Lower Grade Glioma	60	1.40	3.0
The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	20	1.81	3.0
The Cancer Genome Atlas	Pancreatic Adenocarcinoma	18	1.09	3.0
GTEx	Adrenal Gland	12	0.82	2.9
CommonMind	Brain Pre-frontal Cortex	57	1.06	2.9
The Cancer Genome Atlas	Bladder Urothelial Carcinoma	21	1.27	2.9
The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	31	1.14	2.9
The Cancer Genome Atlas	Lung Adenocarcinoma	29	0.99	2.9
The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	30	1.20	2.9
The Cancer Genome Atlas	Soft Tissue Sarcoma	15	1.41	2.9
The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	6	1.18	2.9
METSIM	Adipose	54	1.17	2.8
NTR	Blood	24	1.00	2.8
The Cancer Genome Atlas	Colon Adenocarcinoma	28	1.36	2.8
The Cancer Genome Atlas	Esophageal Carcinoma	9	1.31	2.8
The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	42	1.03	2.8
The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	15	1.14	2.8
The Cancer Genome Atlas	Prostate Adenocarcinoma	62	1.34	2.8
The Cancer Genome Atlas	Testicular Germ Cell Tumors	12	0.94	2.8
The Cancer Genome Atlas	Thyroid Carcinoma	53	1.03	2.8
YFS	Blood	52	1.13	2.7
The Cancer Genome Atlas	Breast Invasive Carcinoma	36	0.82	2.7
The Cancer Genome Atlas	Rectum Adenocarcinoma	5	0.72	2.6