Best TWAS P=4.58e-08 · Best GWAS P=8.17e-09 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | The Cancer Genome Atlas | Breast Invasive Carcinoma | LRFN5 | 0.04 | 0.03 | lasso | 5 | 0.03 | 9.8e-07 | 5.4 | -5.2 | 2.6e-07 | -0.95 | 0.02 | 0.98 | FALSE |
| 2 | The Cancer Genome Atlas | Colon Adenocarcinoma | LRFN5 | 0.10 | 0.07 | lasso | 7 | 0.05 | 4.5e-04 | 5.6 | -5.5 | 5.0e-08 | -0.94 | 0.01 | 0.97 | FALSE |
| 3 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | LRFN5 | 0.03 | 0.03 | enet | 5 | 0.02 | 2.9e-03 | 5.2 | -5.3 | 1.5e-07 | -0.97 | 0.02 | 0.95 | FALSE |
| 4 | The Cancer Genome Atlas | Stomach Adenocarcinoma | LRFN5 | 0.07 | 0.07 | lasso | 5 | 0.06 | 5.5e-05 | 5.6 | -5.5 | 4.6e-08 | -0.98 | 0.01 | 0.98 | TRUE |
| 5 | The Cancer Genome Atlas | Thyroid Carcinoma | LRFN5 | 0.17 | 0.14 | lasso | 4 | 0.13 | 2.0e-12 | 5.6 | -5.4 | 8.7e-08 | -0.98 | 0.01 | 0.99 | FALSE |