Best TWAS P=1.4e-07 · Best GWAS P=4.31e-06 conditioned to 0.785
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Skin Sun Exposed Lower leg | AHSA2 | 0.16 | 0.14 | lasso | 8 | 0.23 | 1.4e-18 | -4.2 | -5.3 | 1.4e-07 | 0.84 | 0.03 | 0.90 | TRUE |
2 | The Cancer Genome Atlas | Rectum Adenocarcinoma | AHSA2 | 0.12 | 0.13 | lasso | 2 | 0.07 | 1.1e-02 | -4.6 | -5.2 | 1.9e-07 | 0.96 | 0.00 | 0.24 | FALSE |