Hub : Traits :

Neuroticism (Nagel 2018)

927 significantly associated models · 165 unique genes.

Significant Loci

#	chr	p0	p1	# assoc genes	# joint genes	best TWAS P	best SNP P	cond SNP P	% var exp	joint genes
1	1	7715776	9571422	2	1	6.7e-08	1.8e-08	9.3e-08	10	RERE
2	1	20434402	22200998	1	1	2.9e-07	4.8e-07	5.8e-02	86	EIF4G3
3	1	86635245	88077288	1	1	5.9e-08	6.1e-06	1.8e-05	10	SEP15
4	1	171053153	172474017	1	1	8.2e-09	2.3e-07	1.8e-02	79	METTL13
5	1	173437024	175663031	1	1	2.4e-07	1.7e-09	1.0e+00	100	RABGAP1L
6	1	201610247	202106797	1	1	3.0e-07	4.0e-08	3.1e-02	85	SHISA4
7	2	23913985	24468132	1	1	3.1e-08	1.6e-05	3.5e-01	95	UBXN2A
8	2	60707588	62107632	1	1	1.4e-07	4.3e-06	7.9e-01	100	AHSA2
9	2	86531748	87557137	1	1	2.1e-07	1.7e-07	1.9e-02	80	PLGLB1
10	2	147993969	149475737	2	1	8.5e-14	3.8e-14	6.6e-03	87	ORC4L
11	3	16154636	17814553	1	1	5.4e-10	4.5e-11	1.9e-03	78	PLCL2
12	3	35439546	36079910	1	1	4.3e-10	8.6e-12	3.1e-03	81	ARPP21
13	3	43931484	45460914	2	1	1.4e-07	1.3e-05	9.0e-01	100	MPRIPP1
14	3	49598064	51234774	6	1	4.4e-08	4.4e-08	1.0e+00	100	HYAL1
15	3	51616334	53015839	1	1	4.9e-08	1.2e-06	9.8e-02	88	WDR82
16	3	135273949	137261517	5	1	2.4e-12	7.4e-13	1.0e+00	100	PCCB
17	4	14777384	16291144	1	1	1.5e-08	1.3e-06	3.6e-01	96	CC2D2A
18	4	41746460	42336312	1	1	1.2e-07	6.4e-08	2.1e-01	95	SLC30A9
19	4	89947254	91439574	1	1	1.4e-08	3.8e-09	1.0e+00	100	SNCA
20	4	118707160	119423789	1	1	2.9e-08	2.2e-06	1.1e-01	89	NDST3
21	5	86867897	88677293	4	5	8.8e-12	3.6e-10	1.0e+00	100	LINC00461 LOC645323 TMEM161B TMEM161B-AS1
22	5	106500969	108412472	1	1	6.7e-09	1.8e-10	4.3e-06	48	FBXL17
23	6	100712304	101576316	1	1	2.0e-08	1.9e-09	1.3e-02	83	ASCC3
24	6	126412953	127031550	1	1	7.0e-08	7.9e-08	1.0e+00	100	CENPW
25	7	1580921	2977732	1	1	1.1e-08	4.1e-08	8.7e-03	77	FTSJ2
26	7	11553163	12967449	1	1	1.9e-08	1.3e-09	2.0e-02	85	TMEM106B
27	7	24040297	25508637	1	1	1.9e-07	4.1e-06	2.2e-01	93	DFNA5
28	7	125383444	127590914	1	1	2.7e-07	4.3e-12	7.8e-07	49	GRM8
29	7	136226517	137716835	1	1	6.7e-08	3.9e-08	1.0e+00	100	PTN
30	8	141421996	142253369	1	1	2.0e-07	1.5e-06	7.8e-01	100	PTK2
31	9	95502571	96913764	2	1	1.2e-10	2.4e-10	1.0e+00	100	RP11-165J3.6
32	9	97520168	98975128	1	1	8.1e-12	1.2e-13	4.0e-03	85	PTCH1
33	9	119768572	121177842	1	1	2.5e-11	5.2e-13	2.0e-04	74	TLR4
34	9	126321003	128824378	2	2	1.4e-07	2.1e-07	1.0e+00	100	GAPVD1 NEK6
35	11	12611333	14105497	1	1	4.4e-13	1.3e-11	3.4e-01	98	ARNTL
36	11	31573646	32376894	2	1	3.8e-09	1.9e-10	2.2e-04	66	PAX6
37	11	46010847	48559571	15	7	5.5e-16	1.7e-14	NaN	NaN	ARHGAP1 C1QTNF4 LRP4 MADD NUP160
38	11	56666189	58178587	5	1	2.0e-11	1.0e-10	1.0e+00	100	ZDHHC5
39	11	105180427	106591126	1	1	1.1e-07	2.0e-05	1.9e-01	91	MSANTD4
40	11	112135760	113969669	5	7	3.5e-17	6.2e-17	1.0e+00	100	ANKK1 DRD2 NCAM1 TTC12
41	11	133079948	134525648	1	1	2.2e-08	4.4e-07	2.5e-02	80	IGSF9B
42	12	108763672	110729807	6	1	2.5e-15	5.0e-16	3.0e-02	93	MMAB
43	12	118116461	119551378	2	1	9.9e-10	1.0e-09	1.8e-01	95	TAOK3
44	13	31078511	32595740	1	1	1.7e-07	3.0e-06	2.1e-02	76	B3GALTL
45	13	66643767	68053176	1	1	2.0e-08	4.9e-09	6.5e-07	28	PCDH9
46	13	110849169	112251122	1	1	2.6e-07	1.6e-06	7.8e-01	100	ANKRD10-IT1
47	14	74424938	76226003	6	2	1.1e-13	2.1e-13	4.0e-01	99	AREL1 DLST
48	15	77207277	78806023	1	1	2.9e-08	3.7e-11	1.2e-05	56	LINGO1
49	16	30347731	31860399	12	1	3.3e-11	8.9e-11	1.7e-01	95	RP11-196G11.2
50	16	71093625	71570413	1	1	8.6e-08	3.4e-08	1.4e-01	93	FTSJD1
51	16	86667409	88119671	1	1	3.9e-08	2.1e-08	8.1e-02	90	FBXO31
52	17	1805677	3287175	1	1	7.6e-08	2.2e-11	3.8e-06	52	PAFAH1B1
53	17	17017584	18914778	3	1	2.6e-08	3.1e-07	3.4e-03	67	SREBF1
54	17	37516722	38943319	2	1	6.1e-09	1.5e-08	2.1e-01	95	MED24
55	17	42607368	45796313	21	1	2.3e-29	1.0e-29	5.4e-03	94	WNT3
56	17	78763580	79380547	2	1	1.1e-12	2.8e-12	9.6e-02	94	AATK
57	18	30921425	31568499	1	1	5.2e-10	1.1e-09	2.5e-01	96	ASXL3
58	18	34124783	35844220	1	2	1.2e-09	1.9e-20	6.2e-08	66	CELF4
59	18	52209411	54028036	1	1	2.2e-07	8.1e-10	1.0e-08	13	TCF4
60	19	32209988	33668090	2	1	1.6e-08	3.5e-08	3.3e-01	97	ZNF507
61	20	2429222	3839754	1	1	6.1e-08	1.1e-05	2.5e-01	93	FASTKD5
62	20	32594714	34109427	2	1	2.0e-08	7.3e-08	1.0e+00	100	NCOA6
63	20	43958786	45456440	2	2	1.1e-10	6.4e-11	1.0e+00	100	CD40 SLC12A5
64	22	40472399	42892596	13	1	7.2e-13	5.2e-14	1.6e-02	90	SLC25A17

Pleiotropic Associations

Trait	chisq ratio	# genes⁺	# genes⁺⁺	% genes⁺⁺	corr	corr P	genes
Neuroticism	14.71	76	54	120.0	1.00	8.2e-86	AATK AHSA2 ANKK1 AREL1 ARHGAP1 ARNTL ARPP21 ASCC3 ASXL3 B3GALTL C1QTNF4 CC2D2A CD40 CELF4 CENPW DFNA5 DLST DRD2 EIF4G3 FASTKD5 FBXL17 FBXO31 FTSJ2 FTSJD1 GAPVD1 GRM8 HYAL1 IGSF9B LINC00461 LINGO1 LOC645323 LRP4 MADD MED24 METTL13 MMAB MPRIPP1 MSANTD4 NCAM1 NCOA6 NDST3 NEK6 NUP160 ORC4L PAFAH1B1 PAX6 PCCB PCDH9 PLCL2 PLGLB1 PTCH1 PTK2 PTN RABGAP1L RERE RP11-165J3.6 RP11-196G11.2 SEP15 SHISA4 SLC12A5 SLC25A17 SLC30A9 SNCA SREBF1 TAOK3 TCF4 TLR4 TMEM106B TMEM161B TMEM161B-AS1 TTC12 UBXN2A WDR82 WNT3 ZDHHC5 ZNF507
Neuroticism score	13.88	71	39	86.7	0.99	2.3e-73	AATK AHSA2 ANKK1 ANKRD10-IT1 AREL1 ARHGAP1 ARNTL ARPP21 ASCC3 ASXL3 B3GALTL C1QTNF4 CC2D2A CD40 CELF4 DFNA5 DLST DRD2 EIF4G3 FBXL17 FBXO31 FTSJ2 FTSJD1 GAPVD1 GRM8 HYAL1 IGSF9B LINC00461 LINGO1 LOC645323 LRP4 MADD MED24 METTL13 MMAB NCAM1 NCOA6 NDST3 NEK6 NUP160 ORC4L PAFAH1B1 PAX6 PCCB PCDH9 PLCL2 PLGLB1 PTCH1 PTK2 PTN RERE RP11-165J3.6 RP11-196G11.2 SHISA4 SLC12A5 SLC25A17 SLC30A9 SNCA SREBF1 TAOK3 TCF4 TLR4 TMEM106B TMEM161B TMEM161B-AS1 TTC12 UBXN2A WDR82 WNT3 ZDHHC5 ZNF507
Depressed Affect (Nagel 2018)	12.22	61	31	68.9	0.99	2.1e-55	AATK ANKK1 AREL1 ARHGAP1 ARNTL ARPP21 ASCC3 ASXL3 B3GALTL C1QTNF4 CC2D2A CD40 CELF4 DFNA5 DLST DRD2 FASTKD5 FBXO31 FTSJ2 FTSJD1 GRM8 LINC00461 LINGO1 LOC645323 LRP4 MADD MED24 METTL13 MMAB MSANTD4 NCAM1 NEK6 NUP160 ORC4L PAFAH1B1 PCCB PCDH9 PLCL2 PTCH1 PTK2 PTN RABGAP1L RERE RP11-165J3.6 RP11-196G11.2 SEP15 SHISA4 SLC12A5 SNCA SREBF1 TAOK3 TCF4 TLR4 TMEM106B TMEM161B TMEM161B-AS1 TTC12 UBXN2A WNT3 ZDHHC5 ZNF507
Worry (Nagel 2018)	11.00	53	27	60.0	0.98	5.5e-43	AATK AHSA2 ANKK1 ANKRD10-IT1 AREL1 ARNTL ARPP21 ASXL3 B3GALTL C1QTNF4 CELF4 CENPW DFNA5 DLST DRD2 EIF4G3 FASTKD5 FBXL17 GAPVD1 HYAL1 IGSF9B LOC645323 MADD MED24 METTL13 MMAB MPRIPP1 NCAM1 NCOA6 NDST3 NEK6 NUP160 ORC4L PAX6 PCCB PLCL2 PLGLB1 PTCH1 PTN RABGAP1L RP11-165J3.6 RP11-196G11.2 SLC12A5 SLC25A17 SLC30A9 SNCA TMEM106B TMEM161B TMEM161B-AS1 TTC12 WDR82 WNT3 ZDHHC5
Mood swings	9.24	30	12	26.7	0.98	9.1e-25	ANKK1 AREL1 ASCC3 ASXL3 C1QTNF4 CD40 CELF4 DLST DRD2 FBXO31 FTSJD1 MADD METTL13 MPRIPP1 NCAM1 NUP160 PLCL2 PTK2 RABGAP1L RP11-165J3.6 RP11-196G11.2 SLC12A5 SLC25A17 SNCA TCF4 TLR4 TMEM106B TTC12 WNT3 ZNF507
Miserableness	9.16	29	16	35.6	0.98	4.0e-22	ANKK1 ARHGAP1 ARNTL ARPP21 ASCC3 B3GALTL C1QTNF4 CD40 CELF4 DRD2 FTSJ2 LINGO1 LRP4 MADD METTL13 MMAB NCAM1 NDST3 NUP160 ORC4L PAFAH1B1 PCCB PCDH9 RP11-165J3.6 TCF4 TMEM106B UBXN2A WNT3 ZNF507
Guilty feelings	8.28	20	9	20.0	0.97	2.2e-14	AATK ANKK1 AREL1 ARNTL ARPP21 C1QTNF4 CD40 DLST DRD2 LINGO1 MADD METTL13 NCAM1 PAFAH1B1 PTCH1 SHISA4 TTC12 UBXN2A WNT3 ZDHHC5
Suffer from 'nerves'	8.04	12	4	8.9	0.95	4.5e-08	AATK ANKK1 AREL1 ARHGAP1 B3GALTL C1QTNF4 DLST MADD NUP160 RERE TTC12 WDR82
Depression (Nagel 2018)	8.02	23	5	11.1	0.98	2.7e-16	AATK ANKK1 C1QTNF4 CELF4 FASTKD5 FTSJ2 HYAL1 MADD NCAM1 NUP160 PCCB PCDH9 PLCL2 RERE RP11-165J3.6 SLC12A5 SNCA TAOK3 TMEM106B UBXN2A WNT3 ZDHHC5 ZNF507
Sensitivity / hurt feelings	7.78	23	7	15.6	0.98	5.2e-18	ANKK1 CELF4 DRD2 GAPVD1 GRM8 IGSF9B METTL13 MMAB NCAM1 NDST3 ORC4L PCCB PLCL2 PTCH1 PTK2 PTN RP11-165J3.6 SREBF1 TAOK3 TMEM161B TTC12 WNT3 ZDHHC5
Neuroticism (2016)	7.77	15	2	4.4	0.98	3.7e-12	AREL1 C1QTNF4 CELF4 DRD2 LINC00461 MADD MPRIPP1 PAX6 PCDH9 SLC25A17 TAOK3 TCF4 TLR4 WDR82 WNT3
Worrier / anxious feelings	7.72	30	12	26.7	0.98	1.8e-21	AHSA2 AREL1 ARNTL ARPP21 B3GALTL DFNA5 DLST EIF4G3 GAPVD1 HYAL1 IGSF9B LINGO1 LOC645323 METTL13 MMAB NDST3 ORC4L PAX6 PCCB PLCL2 PTCH1 RP11-165J3.6 RP11-196G11.2 SLC25A17 TCF4 TMEM161B TMEM161B-AS1 WDR82 WNT3 ZDHHC5
Worry too long after embarrassment	7.68	15	9	20.0	0.96	5.9e-10	ANKK1 ANKRD10-IT1 ARNTL ARPP21 DRD2 FBXL17 GAPVD1 LINC00461 MMAB NCAM1 NCOA6 PCCB TTC12 WNT3 ZDHHC5
Fed-up feelings	7.65	28	11	24.4	0.98	7.0e-20	AREL1 ARHGAP1 ARNTL B3GALTL CD40 CELF4 DLST DRD2 EIF4G3 LINC00461 LINGO1 LRP4 MADD NCAM1 ORC4L PAFAH1B1 PCCB PCDH9 PLCL2 PTK2 SEP15 SHISA4 SLC12A5 TLR4 UBXN2A WNT3 ZDHHC5 ZNF507
Frequency of depressed mood in last 2 weeks	7.56	18	1	2.2	0.97	3.6e-12	AATK C1QTNF4 CC2D2A CELF4 DRD2 HYAL1 MADD NCAM1 NUP160 PCCB PCDH9 PLCL2 RP11-165J3.6 TAOK3 TMEM106B UBXN2A WNT3 ZDHHC5
Nervous feelings	7.14	24	7	15.6	0.98	1.4e-18	ANKK1 AREL1 ARNTL ASXL3 B3GALTL C1QTNF4 CELF4 CENPW DLST GAPVD1 HYAL1 LOC645323 MADD NCOA6 NUP160 ORC4L PCCB PTN RP11-196G11.2 SLC25A17 SNCA TMEM161B WDR82 WNT3
Tense / 'highly strung'	6.81	20	4	8.9	0.98	1.5e-15	AATK ANKK1 ANKRD10-IT1 AREL1 ASCC3 DFNA5 DRD2 FTSJD1 HYAL1 LOC645323 NCOA6 ORC4L PCCB RABGAP1L RERE RP11-165J3.6 RP11-196G11.2 SLC25A17 TMEM106B WDR82
Frequency of tenseness / restlessness in last 2 weeks	6.69	13	4	8.9	0.99	8.9e-10	AATK ANKK1 B3GALTL CELF4 DRD2 MMAB PCCB RP11-165J3.6 SREBF1 TMEM106B UBXN2A WDR82 WNT3
Loneliness, isolation	6.58	10	3	6.7	0.96	7.5e-07	C1QTNF4 MADD MED24 NUP160 ORC4L PCDH9 RERE TAOK3 TMEM106B WNT3
Seen doctor (GP) for nerves, anxiety, tension or depression	6.44	15	3	6.7	0.98	8.3e-11	ANKK1 AREL1 ASCC3 ASXL3 B3GALTL CELF4 DFNA5 DRD2 FTSJ2 MED24 SLC12A5 TCF4 TMEM106B TMEM161B TMEM161B-AS1
Irritability	6.39	18	7	15.6	0.97	1.0e-11	AREL1 CELF4 DRD2 FBXL17 FTSJ2 FTSJD1 LINC00461 MMAB MSANTD4 NCOA6 ORC4L PAFAH1B1 PAX6 RP11-196G11.2 SLC25A17 TCF4 TMEM106B WNT3
Frequency of unenthusiasm / disinterest in last 2 weeks	6.03	7	1	2.2	0.98	1.0e-04	ANKK1 CELF4 DRD2 PCCB PCDH9 UBXN2A ZDHHC5
Frequency of tiredness / lethargy in last 2 weeks	5.96	12	3	6.7	0.99	3.5e-09	AATK ARHGAP1 MMAB ORC4L PAFAH1B1 PCCB PTK2 RP11-165J3.6 SHISA4 TTC12 UBXN2A ZDHHC5
Major Depression (MDD)	4.15	5	0	0.0	1.00	3.4e-05	SLC30A9 TAOK3 TCF4 TMEM106B ZDHHC5
Arm fat percentage (left)	3.92	15	9	20.0	-0.40	1.2e-01	ANKRD10-IT1 ARNTL ARPP21 C1QTNF4 CENPW FTSJ2 LINC00461 MADD NUP160 RERE RP11-196G11.2 SHISA4 TTC12 ZDHHC5 ZNF507
Arm fat percentage (right)	3.76	16	8	17.8	-0.19	4.2e-01	ANKK1 ANKRD10-IT1 ARNTL ARPP21 C1QTNF4 CENPW FTSJ2 LINC00461 MADD NUP160 RERE RP11-196G11.2 SHISA4 TTC12 ZDHHC5 ZNF507
Seen a psychiatrist for nerves, anxiety, tension or depression	3.75	1	0	0.0	0.00	1.0e+00	TMEM106B
Body fat percentage	3.61	19	9	20.0	-0.13	5.4e-01	ANKK1 AREL1 ARNTL ARPP21 C1QTNF4 CENPW FTSJ2 LINC00461 MADD NUP160 PTN RERE RP11-196G11.2 SHISA4 TTC12 UBXN2A WNT3 ZDHHC5 ZNF507
Alcohol intake frequency.	3.61	10	6	13.3	-0.30	3.4e-01	C1QTNF4 DRD2 LOC645323 MADD NUP160 PTN TCF4 TMEM161B WNT3 ZDHHC5
Blood White Count	3.58	15	11	24.4	-0.03	9.0e-01	AATK AHSA2 C1QTNF4 CENPW FASTKD5 MADD MED24 NEK6 NUP160 PCCB PTCH1 RERE TMEM161B UBXN2A WNT3
Overall health rating	3.53	6	2	4.4	0.99	9.9e-08	AATK ANKK1 B3GALTL NCAM1 RP11-165J3.6 TTC12
Trunk fat percentage	3.47	18	8	17.8	-0.22	3.2e-01	ANKK1 AREL1 ARNTL ARPP21 C1QTNF4 CENPW LINC00461 MADD NUP160 PTN RERE RP11-196G11.2 SLC25A17 TTC12 UBXN2A WNT3 ZDHHC5 ZNF507
Leg fat percentage (left)	3.42	16	10	22.2	-0.11	6.6e-01	ANKK1 AREL1 ARNTL ARPP21 C1QTNF4 CENPW LINC00461 MADD NDST3 NUP160 RERE RP11-196G11.2 SHISA4 TTC12 UBXN2A ZNF507
Leg fat percentage (right)	3.37	17	10	22.2	-0.06	8.1e-01	ANKK1 AREL1 ARNTL ARPP21 C1QTNF4 CENPW FTSJ2 LINC00461 MADD NDST3 NUP160 RERE RP11-196G11.2 SHISA4 TTC12 UBXN2A ZNF507
Depression (self-reported)	3.06	1	0	0.0	0.00	1.0e+00	TMEM106B
Taking other prescription medications	3.02	2	1	2.2	0.00	1.0e+00	AREL1 DLST
BMI	2.98	16	8	17.8	-0.18	4.5e-01	ANKK1 ARNTL ARPP21 ASCC3 C1QTNF4 FTSJ2 LINC00461 MADD NUP160 PLGLB1 RP11-196G11.2 SHISA4 TLR4 TTC12 WDR82 ZNF507
Number of self-reported non-cancer illnesses	2.97	4	1	2.2	-0.78	2.2e-01	AREL1 ARNTL FTSJ2 TMEM106B
Comparative body size at age 10	2.93	7	4	8.9	-0.98	7.3e-06	C1QTNF4 HYAL1 MADD NCOA6 NUP160 RP11-165J3.6 SLC30A9
Age when periods started (menarche)	2.90	7	6	13.3	0.68	4.2e-02	ARNTL ASCC3 C1QTNF4 CENPW MADD NUP160 WDR82
Hearing difficulty/problems with background noise	2.88	4	0	0.0	0.95	4.6e-02	ARHGAP1 LRP4 PAFAH1B1 WNT3
Body mass index (BMI)	2.83	11	9	20.0	-0.37	2.2e-01	ARNTL ARPP21 ASCC3 C1QTNF4 FTSJ2 LINC00461 MADD NUP160 RP11-196G11.2 SHISA4 ZNF507
Tanning	2.81	4	1	2.2	-0.07	9.1e-01	AREL1 C1QTNF4 MADD NCOA6
Arm fat mass (left)	2.81	13	8	17.8	-0.20	4.5e-01	ANKK1 ARNTL ARPP21 C1QTNF4 FTSJ2 LINC00461 MADD NUP160 RERE RP11-196G11.2 SHISA4 TTC12 ZNF507
Hair/balding pattern: Pattern 4	2.79	2	2	4.4	0.00	1.0e+00	CENPW WNT3
Smoking Status	2.78	9	2	4.4	0.21	5.8e-01	AATK ASCC3 FBXO31 GAPVD1 NUP160 PLCL2 RERE TMEM161B-AS1 WNT3
Arm fat mass (right)	2.78	12	8	17.8	-0.12	6.4e-01	ANKK1 ARNTL ARPP21 C1QTNF4 FTSJ2 LINC00461 MADD NUP160 RP11-196G11.2 SHISA4 TTC12 ZNF507
Pain experienced in last month	2.75	3	0	0.0	0.00	1.0e+00	CENPW MMAB PTK2
Leg fat mass (left)	2.75	14	7	15.6	-0.15	5.5e-01	ANKK1 ARNTL ARPP21 C1QTNF4 FTSJ2 LINC00461 MADD NUP160 RERE RP11-196G11.2 SHISA4 TMEM161B TTC12 ZNF507
Leg fat mass (right)	2.74	15	6	13.3	-0.09	7.1e-01	ANKK1 ARNTL ARPP21 ASCC3 C1QTNF4 FTSJ2 LINC00461 MADD NUP160 RERE RP11-196G11.2 SHISA4 TMEM161B TTC12 ZNF507
Number of treatments/medications taken	2.73	3	2	4.4	0.00	1.0e+00	AREL1 DLST FTSJ2
Current tobacco smoking	2.73	7	1	2.2	0.75	3.3e-02	AATK C1QTNF4 CELF4 GAPVD1 MADD NUP160 SLC25A17
Whole body fat mass	2.70	13	6	13.3	-0.12	6.2e-01	ANKK1 ARNTL ARPP21 C1QTNF4 FTSJ2 LINC00461 MADD NUP160 RERE RP11-196G11.2 SHISA4 TTC12 ZNF507
Health satisfaction	2.65	3	0	0.0	0.00	1.0e+00	ANKK1 DRD2 PCDH9
Trunk fat mass	2.64	13	6	13.3	-0.24	3.4e-01	ANKK1 ARNTL ARPP21 C1QTNF4 LINC00461 MADD NUP160 RERE RP11-196G11.2 SHISA4 TTC12 WNT3 ZNF507
Forced vital capacity (FVC), Best measure	2.64	8	7	15.6	0.07	8.5e-01	C1QTNF4 CENPW LRP4 MADD NUP160 PTCH1 RP11-196G11.2 WNT3
Intelligence (Savage-Jansen 2018)	2.63	14	6	13.3	-0.15	5.9e-01	AATK C1QTNF4 CENPW FBXO31 LINC00461 MADD METTL13 NCAM1 NUP160 PCCB PLCL2 WDR82 WNT3 ZDHHC5
Smoking status: Current	2.63	5	1	2.2	1.00	1.1e-05	AATK C1QTNF4 GAPVD1 MADD NUP160
Body Mass Index (BMI) (2010)	2.59	3	2	4.4	-0.98	3.1e-03	C1QTNF4 MADD NUP160
Schizophrenia (2014)	2.59	8	3	6.7	0.75	3.1e-02	DRD2 IGSF9B PCCB PLCL2 RERE SLC25A17 WDR82 ZDHHC5
HDL Cholesterol	2.58	6	2	4.4	0.56	1.9e-01	ARHGAP1 C1QTNF4 LRP4 MADD MMAB NUP160
Waist circumference	2.58	13	7	15.6	-0.03	9.2e-01	ANKK1 ARNTL ARPP21 C1QTNF4 FTSJ2 LINC00461 MADD NUP160 PTN RP11-196G11.2 SHISA4 TTC12 ZNF507
Headache pain in last month	2.56	4	1	2.2	0.99	5.1e-03	DFNA5 TLR4 WNT3 ZDHHC5
Long-standing illness, disability or infirmity	2.55	3	0	0.0	0.99	9.5e-03	ANKK1 TMEM161B-AS1 TTC12
Forced vital capacity (FVC)	2.54	8	7	15.6	0.04	9.2e-01	C1QTNF4 CENPW MADD NDST3 NUP160 PTCH1 RP11-196G11.2 WNT3
Sitting height	2.52	15	10	22.2	0.06	8.0e-01	AATK C1QTNF4 CENPW EIF4G3 FBXO31 GAPVD1 MADD MPRIPP1 NCOA6 NUP160 PTCH1 UBXN2A WDR82 WNT3 ZDHHC5
Verbal and Numeric Reasoning (VNR)	2.51	9	1	2.2	0.11	7.5e-01	C1QTNF4 CENPW LINC00461 MADD METTL13 NCAM1 NUP160 PLCL2 WDR82
Hand grip strength (left)	2.47	8	5	11.1	0.28	4.3e-01	AREL1 ARPP21 C1QTNF4 LINGO1 MADD NUP160 TCF4 WNT3
Systolic Blood Pressure	2.42	13	10	22.2	0.50	5.7e-02	AREL1 ARHGAP1 ARNTL C1QTNF4 GAPVD1 LRP4 MADD NUP160 ORC4L PAFAH1B1 RERE SREBF1 ZDHHC5
Fluid intelligence score	2.42	6	2	4.4	0.18	7.0e-01	C1QTNF4 MADD METTL13 NUP160 PCCB PLCL2
Other serious medical condition/disability diagnosed by doctor	2.41	2	0	0.0	1.00	3.5e-03	ANKK1 TTC12
Mean time to correctly identify matches	2.41	4	2	4.4	-0.43	5.7e-01	ARHGAP1 FBXO31 LRP4 TMEM161B-AS1
Stomach or abdominal pain in last month	2.40	1	0	0.0	0.00	1.0e+00	PCCB
Ever unenthusiastic/disinterested for a whole week	2.40	1	0	0.0	0.00	1.0e+00	WNT3
Average weekly red wine intake	2.40	3	0	0.0	0.00	1.0e+00	LOC645323 TMEM161B ZDHHC5
Medication: Paracetamol	2.38	1	1	2.2	0.00	1.0e+00	WNT3
Medication for pain relief, constipation, heartburn	2.37	5	1	2.2	-0.98	3.0e-03	AREL1 PCDH9 RABGAP1L RP11-165J3.6 WNT3
Qualifications: College or University degree	2.30	11	5	11.1	-0.53	7.7e-02	B3GALTL CELF4 FBXO31 FTSJ2 LINC00461 LOC645323 PTN SHISA4 TMEM161B WNT3 ZDHHC5
Ever smoked	2.29	4	1	2.2	-0.16	8.0e-01	AATK GAPVD1 TMEM161B-AS1 WDR82
Neck or shoulder pain in last month	2.27	2	1	2.2	0.00	1.0e+00	ASXL3 RABGAP1L
Comparative height size at age 10	2.26	15	6	13.3	-0.18	4.9e-01	ANKK1 C1QTNF4 CENPW DLST EIF4G3 MADD METTL13 NCOA6 NUP160 PCCB PTCH1 SNCA TCF4 WDR82 WNT3
Bipolar Disorder or Schizophrenia	2.24	8	2	4.4	0.80	1.7e-02	IGSF9B MED24 NDST3 PLCL2 RERE SLC12A5 SLC25A17 WDR82
Medication: Paracetamol	2.23	1	1	2.2	0.00	1.0e+00	WNT3
Schizophrenia (2018)	2.19	5	2	4.4	0.68	2.0e-01	IGSF9B PCCB RERE SLC25A17 ZDHHC5
Reaction Time	2.19	4	1	2.2	-0.56	4.4e-01	ARHGAP1 LRP4 MED24 RERE
Chronotype (morning person)	2.19	5	1	2.2	0.93	2.3e-02	C1QTNF4 EIF4G3 HYAL1 TMEM161B TMEM161B-AS1
Qualifications: None of the above	2.18	6	1	2.2	0.42	4.1e-01	B3GALTL CELF4 LOC645323 PLCL2 PTN TMEM161B
Chest pain or discomfort	2.18	2	0	0.0	0.00	1.0e+00	ASXL3 MED24
Back pain experienced in last month	2.18	1	0	0.0	0.00	1.0e+00	PTK2
Financial difficulties in last 2 years	2.17	1	0	0.0	0.00	1.0e+00	DRD2
Forced expiratory volume in 1-second (FEV1)	2.16	8	4	8.9	-0.03	9.4e-01	C1QTNF4 CENPW MADD NDST3 NUP160 PTCH1 RP11-196G11.2 WNT3
Past tobacco smoking	2.15	2	0	0.0	0.00	1.0e+00	GAPVD1 TMEM161B-AS1
Alcohol usually taken with meals	2.15	3	2	4.4	0.00	1.0e+00	CELF4 SLC30A9 ZDHHC5
Townsend deprivation index at recruitment	2.13	1	0	0.0	0.00	1.0e+00	MADD
Hip circumference	2.11	14	5	11.1	-0.29	2.7e-01	ANKK1 ANKRD10-IT1 C1QTNF4 CENPW FTSJ2 GAPVD1 LINC00461 MADD NUP160 PTCH1 RP11-196G11.2 SHISA4 SREBF1 ZNF507
Prospective memory result	2.09	1	0	0.0	0.00	1.0e+00	PLCL2
Average weekly champagne plus white wine intake	2.08	1	0	0.0	0.00	1.0e+00	WNT3
Alzheimer’s Disease (including proxy)	2.07	3	0	0.0	0.99	8.7e-03	C1QTNF4 MADD NUP160
Lung FVC	2.06	8	5	11.1	-0.37	3.7e-01	AHSA2 CENPW HYAL1 PTCH1 RP11-196G11.2 TCF4 UBXN2A WNT3
Forced expiratory volume in 1-second (FEV1), Best measure	2.06	7	4	8.9	0.16	7.0e-01	C1QTNF4 CENPW MADD NUP160 PTCH1 RP11-196G11.2 WNT3
Wheeze or whistling in the chest in last year	2.03	1	0	0.0	0.00	1.0e+00	ANKK1
Hair/balding pattern: Pattern 3	1.99	2	2	4.4	0.00	1.0e+00	CENPW WNT3
Knee pain experienced in last month	1.98	1	0	0.0	0.00	1.0e+00	RABGAP1L
Qualifications: nursing, teaching	1.96	1	0	0.0	0.00	1.0e+00	B3GALTL
Standing height	1.93	16	11	24.4	0.17	4.9e-01	AATK C1QTNF4 CENPW EIF4G3 FTSJ2 MADD METTL13 NCOA6 NUP160 PTCH1 RP11-165J3.6 SNCA TMEM106B UBXN2A WDR82 WNT3
Handedness (chirality/laterality): Left-handed	1.93	1	1	2.2	0.00	1.0e+00	WNT3
Relative age of first facial hair	1.92	1	1	2.2	0.00	1.0e+00	WNT3
Schizophrenia vs Biploar Disorder	1.91	2	0	0.0	0.00	1.0e+00	ARNTL MED24
Myopia	1.91	2	0	0.0	0.00	1.0e+00	FTSJ2 MADD
Bipolar Disorder (2018)	1.89	2	0	0.0	0.00	1.0e+00	MED24 WDR82
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.89	1	0	0.0	0.00	1.0e+00	RABGAP1L
Waist Hip Ratio (WHR)	1.88	12	8	17.8	0.72	7.6e-03	CC2D2A CENPW GAPVD1 HYAL1 PCCB PLCL2 PTK2 SREBF1 TTC12 UBXN2A WDR82 WNT3
Alcohol drinker status: Never	1.88	1	0	0.0	0.00	1.0e+00	C1QTNF4
Qualifications: A levels/AS levels or equivalent	1.87	3	0	0.0	0.00	1.0e+00	LINC00461 METTL13 NDST3
Pack years adult smoking proportion	1.82	1	0	0.0	0.00	1.0e+00	CELF4
Systolic blood pressure, automated reading	1.80	8	2	4.4	0.00	1.0e+00	AREL1 ARNTL GAPVD1 LRP4 MADD PAFAH1B1 RERE ZDHHC5
Pack years of smoking	1.78	1	0	0.0	0.00	1.0e+00	CELF4
Hand grip strength (right)	1.77	7	3	6.7	0.21	5.9e-01	ARPP21 C1QTNF4 LINGO1 MADD NDST3 NUP160 WNT3
Alcohol intake versus 10 years previously	1.77	1	0	0.0	0.00	1.0e+00	FTSJ2
High blood pressure	1.76	5	2	4.4	0.24	6.9e-01	ARHGAP1 ARNTL LRP4 MADD RERE
Trunk fat-free mass	1.76	13	6	13.3	0.14	6.4e-01	ARHGAP1 ASCC3 C1QTNF4 CENPW EIF4G3 GAPVD1 MADD NCOA6 NUP160 PTCH1 SHISA4 TMEM161B UBXN2A
Trunk predicted mass	1.75	13	7	15.6	0.14	6.4e-01	ARHGAP1 ASCC3 C1QTNF4 CENPW EIF4G3 GAPVD1 MADD NCOA6 NUP160 PTCH1 SHISA4 TMEM161B UBXN2A
Heel T-Score	1.74	10	5	11.1	-0.18	6.2e-01	AREL1 ARHGAP1 B3GALTL DLST LRP4 MADD RERE SLC25A17 WNT3 ZDHHC5
Number of incorrect matches in round	1.73	1	0	0.0	0.00	1.0e+00	NDST3
Age at first live birth	1.73	1	0	0.0	0.00	1.0e+00	CELF4
Vascular/heart problems diagnosed by doctor	1.72	4	1	2.2	-0.50	5.0e-01	ARHGAP1 ARNTL LRP4 MADD
Hayfever, allergic rhinitis or eczema	1.71	4	1	2.2	-0.09	9.1e-01	MED24 PLCL2 RERE SLC30A9
Cardiovascular Disease	1.70	8	0	0.0	0.33	3.9e-01	ANKK1 ARNTL FTSJ2 PCCB RP11-196G11.2 SHISA4 SREBF1 TTC12
Relative age voice broke	1.70	1	1	2.2	0.00	1.0e+00	WNT3
Hypertension (Self-reported)	1.69	6	0	0.0	0.24	6.4e-01	ARHGAP1 ARNTL LRP4 MADD RERE SHISA4
Impedance of leg (left)	1.68	11	6	13.3	0.16	6.4e-01	AREL1 ASCC3 C1QTNF4 CENPW GAPVD1 HYAL1 LINC00461 MADD NCOA6 UBXN2A WNT3
Blood Red Count	1.67	16	11	24.4	0.51	4.4e-02	ANKRD10-IT1 ARNTL CC2D2A CENPW DRD2 EIF4G3 LINC00461 MADD METTL13 PLCL2 RP11-196G11.2 TMEM161B UBXN2A WDR82 WNT3 ZDHHC5
Height	1.67	27	18	40.0	-0.10	6.0e-01	AATK AREL1 C1QTNF4 CENPW EIF4G3 FTSJ2 GAPVD1 HYAL1 MADD METTL13 NCOA6 NDST3 NUP160 ORC4L PAFAH1B1 PCCB PTCH1 RABGAP1L RERE RP11-165J3.6 SLC30A9 SNCA TCF4 TMEM106B UBXN2A WDR82 WNT3
Allergy or Eczema	1.67	6	3	6.7	-0.09	8.6e-01	MED24 PLCL2 RERE SLC12A5 SLC25A17 SLC30A9
Allergy	1.67	3	2	4.4	0.00	1.0e+00	MED24 RERE SLC30A9
Time employed in main current job	1.67	1	1	2.2	0.00	1.0e+00	WNT3
Impedance of leg (right)	1.65	11	6	13.3	0.42	1.9e-01	AREL1 C1QTNF4 GAPVD1 HYAL1 LINC00461 MADD NCOA6 NUP160 PTCH1 SLC30A9 UBXN2A
Hair/balding pattern: Pattern 2	1.64	2	1	2.2	0.00	1.0e+00	CENPW WNT3
Peak expiratory flow (PEF)	1.64	2	1	2.2	0.00	1.0e+00	NDST3 WNT3
Hearing difficulty/problems: Yes	1.62	3	0	0.0	0.00	1.0e+00	FBXL17 MMAB PTK2
Medication: Metformin	1.62	2	0	0.0	0.00	1.0e+00	C1QTNF4 MADD
Leg pain on walking	1.61	1	0	0.0	0.00	1.0e+00	WNT3
Mouth/teeth dental problems	1.60	1	0	0.0	0.00	1.0e+00	WNT3
Weight	1.58	13	4	8.9	-0.21	4.6e-01	ANKK1 ARPP21 ASCC3 C1QTNF4 CENPW GAPVD1 LINC00461 MADD NCOA6 RP11-196G11.2 SHISA4 TMEM161B ZNF507
Forced expiratory volume in 1-second (FEV1), predicted	1.58	4	1	2.2	0.54	4.6e-01	C1QTNF4 CENPW NUP160 PTCH1
Qualifications: O levels/GCSEs or equivalent	1.57	1	0	0.0	0.00	1.0e+00	PLCL2
Average weekly beer plus cider intake	1.57	1	0	0.0	0.00	1.0e+00	CELF4
Risk taking	1.57	1	0	0.0	0.00	1.0e+00	PCCB
Birth weight	1.55	3	1	2.2	0.00	1.0e+00	C1QTNF4 CENPW PTCH1
Diastolic blood pressure, automated reading	1.55	6	4	8.9	0.16	7.7e-01	ARNTL LINC00461 MADD PAFAH1B1 RERE SHISA4
Fasting Glucose	1.52	1	1	2.2	0.00	1.0e+00	MADD
Eye problems/disorders: Diabetes related eye disease	1.52	1	0	0.0	0.00	1.0e+00	C1QTNF4
Illnesses of father: High blood pressure	1.52	1	0	0.0	0.00	1.0e+00	MADD
Heel bone mineral density (BMD) T-score, automated (right)	1.51	3	3	6.7	0.00	1.0e+00	ARHGAP1 LRP4 RERE
Emphysema/chronic bronchitis	1.50	1	0	0.0	0.00	1.0e+00	MED24
Mineral and other dietary supplements	1.49	1	0	0.0	0.00	1.0e+00	SLC30A9
Ever had prostate specific antigen (PSA) test	1.49	2	0	0.0	0.00	1.0e+00	PAFAH1B1 TMEM161B
Whole body fat-free mass	1.48	9	4	8.9	0.18	6.4e-01	ASCC3 CENPW GAPVD1 LINC00461 NCOA6 PTCH1 SHISA4 TMEM161B UBXN2A
Arm fat-free mass (left)	1.48	8	5	11.1	0.26	5.4e-01	ASCC3 CENPW GAPVD1 LINC00461 NCOA6 PTCH1 SHISA4 TMEM161B
Arm fat-free mass (right)	1.47	8	5	11.1	0.23	5.8e-01	ASCC3 CENPW GAPVD1 LINC00461 NCOA6 PTCH1 SHISA4 TMEM161B
Whole body water mass	1.47	9	4	8.9	0.19	6.3e-01	ASCC3 CENPW GAPVD1 LINC00461 NCOA6 PTCH1 SHISA4 TMEM161B UBXN2A
Impedance of whole body	1.47	12	7	15.6	-0.17	5.9e-01	AREL1 ASCC3 CENPW GAPVD1 HYAL1 LINC00461 NCOA6 SHISA4 SLC30A9 UBXN2A WDR82 WNT3
Arm predicted mass (left)	1.47	8	6	13.3	0.26	5.3e-01	ASCC3 CENPW GAPVD1 LINC00461 NCOA6 PTCH1 SHISA4 TMEM161B
Basal cell carcinoma (self-reported)	1.46	1	0	0.0	0.00	1.0e+00	NCOA6
Arm predicted mass (right)	1.45	8	4	8.9	0.23	5.8e-01	ASCC3 CENPW GAPVD1 LINC00461 NCOA6 PTCH1 SHISA4 TMEM161B
Impedance of arm (left)	1.44	10	5	11.1	-0.15	6.8e-01	ASCC3 CENPW GAPVD1 HYAL1 NCOA6 SHISA4 TMEM161B WDR82 WNT3 ZDHHC5
Rheumatoid Arthritis	1.42	2	0	0.0	0.00	1.0e+00	CD40 SLC12A5
Hair Pigment	1.41	4	2	4.4	-0.43	5.7e-01	FBXO31 NCOA6 SLC25A17 WNT3
Number of full brothers	1.41	1	0	0.0	0.00	1.0e+00	WNT3
Respiratory disease	1.40	2	2	4.4	0.00	1.0e+00	MED24 RERE
Impedance of arm (right)	1.40	11	6	13.3	-0.20	5.6e-01	ASCC3 CENPW GAPVD1 HYAL1 NCOA6 SHISA4 TMEM106B TMEM161B WDR82 WNT3 ZDHHC5
Lung FEV1/FVC ratio	1.39	8	6	13.3	-0.39	3.4e-01	AHSA2 AREL1 CENPW DLST PTCH1 RERE SHISA4 ZDHHC5
Basal metabolic rate	1.39	8	6	13.3	0.24	5.7e-01	ASCC3 CENPW GAPVD1 LINC00461 NCOA6 PTCH1 SHISA4 TMEM161B
Asthma	1.38	2	1	2.2	0.00	1.0e+00	MED24 RERE
Medication for cholesterol, blood pressure or diabetes	1.37	1	0	0.0	0.00	1.0e+00	TMEM161B-AS1
Mean Putamen Volume	1.36	1	0	0.0	0.00	1.0e+00	WNT3
Supplements: Glucosamine	1.36	1	0	0.0	0.00	1.0e+00	SLC30A9
Leg fat-free mass (right)	1.36	7	5	11.1	0.21	6.4e-01	C1QTNF4 CENPW GAPVD1 LINC00461 NCOA6 PTCH1 SHISA4
Leg predicted mass (right)	1.36	7	5	11.1	0.21	6.5e-01	C1QTNF4 CENPW GAPVD1 LINC00461 NCOA6 PTCH1 SHISA4
Leg predicted mass (left)	1.35	8	5	11.1	0.23	5.8e-01	ASCC3 C1QTNF4 CENPW GAPVD1 LINC00461 NCOA6 PTCH1 SHISA4
Leg fat-free mass (left)	1.34	8	5	11.1	0.24	5.7e-01	ASCC3 C1QTNF4 CENPW GAPVD1 LINC00461 NCOA6 PTCH1 SHISA4
Birth weight of first child	1.34	1	0	0.0	0.00	1.0e+00	PAFAH1B1
Heel bone mineral density (BMD) T-score, automated (left)	1.33	3	3	6.7	0.00	1.0e+00	ARHGAP1 LRP4 RERE
Asthma (self-reported)	1.33	2	1	2.2	0.00	1.0e+00	MED24 RERE
Fractured/broken bones in last 5 years	1.30	1	0	0.0	0.00	1.0e+00	WNT3
Hypothyroidism (self reported)	1.29	3	1	2.2	0.00	1.0e+00	C1QTNF4 MADD RERE
Vitamin and mineral supplements	1.28	1	0	0.0	0.00	1.0e+00	SLC30A9
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.28	2	2	4.4	0.00	1.0e+00	RP11-196G11.2 WNT3
Pulse rate, automated reading	1.26	5	0	0.0	0.99	1.8e-03	LINC00461 ORC4L RABGAP1L TMEM161B-AS1 ZDHHC5
Mouth/teeth dental problems: Mouth ulcers	1.23	1	1	2.2	0.00	1.0e+00	WNT3
Diabetes diagnosed by doctor	1.21	1	0	0.0	0.00	1.0e+00	CENPW
Type 2 Diabetes (T2D) (2018)	1.20	2	0	0.0	0.00	1.0e+00	C1QTNF4 CENPW
Pulse rate	1.20	1	0	0.0	0.00	1.0e+00	SEP15
Hypothyroidism/myxoedema (self-reported)	1.17	1	0	0.0	0.00	1.0e+00	RERE
Supplements: Vitamin C	1.16	1	0	0.0	0.00	1.0e+00	WNT3
Ovarian Cancer	1.14	1	1	2.2	0.00	1.0e+00	WNT3
Triglycerides	1.14	1	0	0.0	0.00	1.0e+00	NCOA6
Number of live births	1.14	1	0	0.0	0.00	1.0e+00	WNT3
Irritable Bowel Disease (IBD)	1.12	3	1	2.2	0.00	1.0e+00	AHSA2 CD40 SLC12A5
Primary Biliary Cirrhosis	1.07	2	0	0.0	0.00	1.0e+00	PLCL2 WNT3
Medication: Ventolin 100micrograms inhaler	1.06	1	0	0.0	0.00	1.0e+00	MED24
Blood Eosinophil Count	1.05	10	5	11.1	-0.66	3.8e-02	AHSA2 EIF4G3 MED24 ORC4L PLCL2 RERE SLC25A17 SREBF1 WDR82 WNT3
Ulcerative Colitis (UC)	1.04	2	1	2.2	0.00	1.0e+00	AHSA2 MED24
Crohns Disease (2017)	1.03	3	0	0.0	0.00	1.0e+00	AHSA2 CD40 SLC12A5
Illnesses of father: Heart disease	1.02	1	0	0.0	0.00	1.0e+00	WNT3
Blood Platelet Count	0.96	12	11	24.4	0.08	7.9e-01	AREL1 C1QTNF4 DLST HYAL1 LINC00461 MADD MED24 METTL13 NUP160 PCCB WDR82 ZDHHC5
Breast Cancer	0.92	1	1	2.2	0.00	1.0e+00	WNT3

Associations by panel

study	tissue	# hits	% hits/tests	avg chisq
GTEx	Uterus	9	1.59	3.3
GTEx	Small Intestine Terminal Ileum	5	1.08	3.2
GTEx	Brain Hippocampus	7	1.34	3.1
GTEx	Brain Cortex	14	1.35	3.0
GTEx	Ovary	11	1.21	3.0
GTEx	Artery Coronary	15	1.27	2.9
GTEx	Brain Frontal Cortex BA9	10	1.08	2.9
GTEx	Vagina	5	0.79	2.9
GTEx	Brain Hypothalamus	5	0.85	2.8
GTEx	Brain Nucleus accumbens basal ganglia	10	1.15	2.8
GTEx	Brain Putamen basal ganglia	6	0.96	2.8
GTEx	Cells EBV-transformed lymphocytes	13	0.91	2.8
GTEx	Esophagus Gastroesophageal Junction	16	1.11	2.8
GTEx	Liver	9	1.26	2.8
GTEx	Brain Caudate basal ganglia	9	0.98	2.7
GTEx	Prostate	6	0.72	2.7
GTEx	Spleen	12	0.85	2.7
GTEx	Stomach	14	0.96	2.7
The Cancer Genome Atlas	Esophageal Carcinoma	6	0.88	2.7
GTEx	Brain Cerebellar Hemisphere	12	0.81	2.6
GTEx	Breast Mammary Tissue (Female)	14	0.85	2.6
GTEx	Colon Sigmoid	14	0.96	2.6
GTEx	Colon Transverse	19	0.92	2.6
GTEx	Esophagus Muscularis	24	0.74	2.6
GTEx	Heart Atrial Appendage	14	0.89	2.6
GTEx	Heart Left Ventricle	13	0.85	2.6
GTEx	Pancreas	13	0.80	2.6
GTEx	Pituitary	12	1.08	2.6
GTEx	Skin Not Sun Exposed Suprapubic	18	0.73	2.6
GTEx	Testis	25	0.79	2.6
GTEx	Adipose Visceral Omentum	14	0.69	2.5
GTEx	Adrenal Gland	10	0.69	2.5
GTEx	Artery Aorta	18	0.60	2.5
GTEx	Brain Cerebellum	13	0.66	2.5
GTEx	Breast Mammary Tissue	18	0.91	2.5
GTEx	Breast Mammary Tissue (Male)	10	0.84	2.5
GTEx	Skin Sun Exposed Lower leg	23	0.63	2.5
GTEx	Esophagus Mucosa	24	0.72	2.4
GTEx	Lung	13	0.45	2.4
GTEx	Muscle Skeletal	18	0.62	2.4
GTEx	Thyroid	23	0.58	2.4
GTEx	Whole Blood	12	0.60	2.4
GTEx	Artery Tibial	14	0.37	2.3
GTEx	Cells Transformed fibroblasts	21	0.50	2.3
GTEx	Nerve Tibial	19	0.44	2.3
ROSMAP	Brain Pre-frontal Cortex	19	0.43	2.3
The Cancer Genome Atlas	Bladder Urothelial Carcinoma	12	0.73	2.3
The Cancer Genome Atlas	Glioblastoma Multiforme	6	0.59	2.3
The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	14	0.56	2.3
The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	11	0.69	2.3
The Cancer Genome Atlas	Pancreatic Adenocarcinoma	6	0.36	2.3
The Cancer Genome Atlas	Soft Tissue Sarcoma	6	0.56	2.3
The Cancer Genome Atlas	Stomach Adenocarcinoma	10	0.60	2.3
The Cancer Genome Atlas	Uterine Corpus Endometrial Carcinoma	2	0.39	2.3
GTEx	Adipose Subcutaneous	15	0.43	2.2
NTR	Blood	7	0.29	2.2
CommonMind	Brain Pre-frontal Cortex	14	0.26	2.2
The Cancer Genome Atlas	Cervical Squamous Cell Carcinoma	6	0.55	2.2
The Cancer Genome Atlas	Colon Adenocarcinoma	7	0.34	2.2
The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	16	0.59	2.2
The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	14	0.68	2.2
The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	5	0.45	2.2
The Cancer Genome Atlas	Lung Adenocarcinoma	13	0.44	2.2
The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	6	0.45	2.2
The Cancer Genome Atlas	Rectum Adenocarcinoma	3	0.43	2.2
The Cancer Genome Atlas	Testicular Germ Cell Tumors	4	0.31	2.2
METSIM	Adipose	15	0.33	2.1
The Cancer Genome Atlas	Breast Invasive Carcinoma	15	0.34	2.1
The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	15	0.37	2.1
The Cancer Genome Atlas	Prostate Adenocarcinoma	21	0.45	2.1
The Cancer Genome Atlas	Skin Cutaneous Melanoma	2	0.38	2.1
The Cancer Genome Atlas	Thyroid Carcinoma	22	0.43	2.1
YFS	Blood	17	0.37	2.0
The Cancer Genome Atlas	Brain Lower Grade Glioma	14	0.33	2.0