Best TWAS P=3.89e-08 · Best GWAS P=1.16e-07 conditioned to 0.0202
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Caudate basal ganglia | OCLN | 0.20 | 0.00 | enet | 22 | 0.13 | 1.3e-04 | -2.3 | -5.1 | 2.7e-07 | 0.34 | 0.02 | 0.08 | FALSE |
| 2 | GTEx | Brain Hypothalamus | GUSBP3 | 0.47 | 0.03 | lasso | 7 | 0.08 | 5.8e-03 | -4.5 | -5.5 | 3.9e-08 | 0.64 | 0.01 | 0.54 | TRUE |
| 3 | GTEx | Skin Not Sun Exposed Suprapubic | OCLN | 0.15 | 0.03 | enet | 14 | 0.11 | 1.3e-06 | -5.1 | -5.1 | 2.8e-07 | 0.82 | 0.00 | 0.99 | FALSE |