TWAS
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Models
Genes
Traits
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Traits
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Blood Red Count
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chr5:75,315,161-76,721,754
Best TWAS P=4.25e-10 · Best GWAS P=4.47e-13 conditioned to 0.000109
75.4M
75.6M
75.8M
76M
76.2M
76.4M
76.6M
76.8M
0
2
4
6
8
10
12
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
3
The Cancer Genome Atlas
Prostate Adenocarcinoma
F2RL1
0.02
0.01
blup
50
0.02
2.2e-03
5.3
-6.2
4.2e-10
-0.26
0.01
0.60
TRUE
2
YFS
Blood
F2R
0.08
0.07
bslmm
562
0.08
1.4e-23
5.8
-5.4
8.0e-08
-0.41
0.93
0.07
TRUE
1
GTEx
Heart Left Ventricle
F2R
0.14
0.02
lasso
6
0.03
1.4e-02
4.5
5.7
1.4e-08
0.42
0.19
0.07
FALSE
4
The Cancer Genome Atlas
Thyroid Carcinoma
F2RL1
0.05
0.03
enet
7
0.03
2.7e-04
4.9
-5.5
4.3e-08
-0.27
0.04
0.31
FALSE