Best TWAS P=4.25e-10 · Best GWAS P=4.47e-13 conditioned to 0.000109
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Heart Left Ventricle | F2R | 0.14 | 0.02 | lasso | 6 | 0.03 | 1.4e-02 | 4.5 | 5.7 | 1.4e-08 | 0.42 | 0.19 | 0.07 | FALSE |
| 2 | YFS | Blood | F2R | 0.08 | 0.07 | bslmm | 562 | 0.08 | 1.4e-23 | 5.8 | -5.4 | 8.0e-08 | -0.41 | 0.93 | 0.07 | TRUE |
| 3 | The Cancer Genome Atlas | Prostate Adenocarcinoma | F2RL1 | 0.02 | 0.01 | blup | 50 | 0.02 | 2.2e-03 | 5.3 | -6.2 | 4.2e-10 | -0.26 | 0.01 | 0.60 | TRUE |
| 4 | The Cancer Genome Atlas | Thyroid Carcinoma | F2RL1 | 0.05 | 0.03 | enet | 7 | 0.03 | 2.7e-04 | 4.9 | -5.5 | 4.3e-08 | -0.27 | 0.04 | 0.31 | FALSE |