Best TWAS P=9.04e-09 · Best GWAS P=4.76e-08 conditioned to 0.409
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | GSTA1 | 0.04 | 0.03 | blup | 34 | 0.04 | 4.0e-04 | 5.4 | 5.8 | 9.0e-09 | 0.88 | 0.01 | 0.95 | TRUE |
2 | The Cancer Genome Atlas | Colon Adenocarcinoma | GSTA1 | 0.08 | 0.06 | blup | 34 | 0.09 | 7.2e-06 | -5.0 | 5.5 | 5.0e-08 | 0.87 | 0.02 | 0.97 | FALSE |
3 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | GSTA1 | 0.16 | 0.17 | lasso | 4 | 0.12 | 1.1e-05 | -5.0 | 5.5 | 4.2e-08 | 0.84 | 0.02 | 0.98 | FALSE |
4 | The Cancer Genome Atlas | Prostate Adenocarcinoma | GSTA1 | 0.04 | 0.03 | blup | 34 | 0.06 | 1.5e-06 | -5.1 | 5.3 | 1.3e-07 | 0.87 | 0.02 | 0.98 | FALSE |
5 | The Cancer Genome Atlas | Stomach Adenocarcinoma | GSTA1 | 0.12 | 0.10 | enet | 4 | 0.11 | 1.4e-08 | -5.0 | 5.5 | 3.8e-08 | 0.93 | 0.01 | 0.99 | FALSE |