Best TWAS P=3.64e-10 · Best GWAS P=3.92e-12 conditioned to 0.00234
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | NTR | Blood | MLLT4 | 0.02 | 0.02 | lasso | 4 | 0.02 | 4.1e-06 | 4.4 | -6.3 | 3.6e-10 | 0.86 | 0.04 | 0.96 | TRUE |
2 | The Cancer Genome Atlas | Testicular Germ Cell Tumors | MLLT4 | 0.16 | 0.04 | blup | 138 | 0.08 | 1.2e-03 | -2.8 | -5.3 | 1.3e-07 | 0.74 | 0.04 | 0.50 | FALSE |