Hub : Genes

MLLT4

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.1450 0.0330 1.2e-13 0.137 0.122 0.134 0.138 0.134 2.7e-16 1.2e-14 5.0e-16 1.8e-16 5.3e-16
2 GTEx Adipose Visceral Omentum 0.2530 0.0790 2.1e-03 -0.005 NA 0.001 NA -0.004 8.8e-01 NA 2.6e-01 NA 6.4e-01
3 GTEx Adrenal Gland 0.1399 0.0600 6.8e-03 0.077 NA 0.028 NA 0.034 1.0e-03 NA 3.6e-02 NA 2.2e-02
4 GTEx Artery Aorta 0.1370 0.0470 4.2e-04 0.091 NA 0.076 NA 0.079 1.1e-05 NA 5.2e-05 NA 4.1e-05
5 GTEx Artery Tibial 0.0824 0.0324 9.3e-04 0.047 NA -0.002 NA 0.025 1.4e-04 NA 5.5e-01 NA 4.1e-03
6 GTEx Brain Cerebellum 0.2260 0.0790 2.4e-03 0.003 NA 0.006 NA 0.004 2.5e-01 NA 2.1e-01 NA 2.4e-01
7 GTEx Muscle Skeletal 0.1359 0.0470 5.1e-04 0.013 NA 0.027 NA 0.021 1.7e-02 NA 9.8e-04 NA 3.2e-03
8 GTEx Skin Sun Exposed Lower leg 0.0550 0.0240 7.2e-03 0.025 NA 0.002 NA 0.015 3.7e-03 NA 2.0e-01 NA 1.9e-02
9 GTEx Whole Blood 0.2480 0.0540 2.5e-06 0.058 NA 0.144 NA 0.142 4.7e-06 NA 3.3e-13 NA 4.8e-13
10 METSIM Adipose 0.0874 0.0229 7.6e-08 0.054 0.058 0.063 0.065 0.065 1.7e-08 3.9e-09 1.1e-09 5.0e-10 4.5e-10
11 NTR Blood 0.0202 0.0069 9.5e-05 0.015 0.013 0.012 0.012 0.016 7.2e-06 3.1e-05 6.1e-05 5.4e-05 4.1e-06
12 ROSMAP Brain Pre-frontal Cortex 0.0575 0.0194 3.1e-04 0.053 0.019 0.029 0.027 0.039 2.1e-07 1.5e-03 1.1e-04 1.7e-04 8.9e-06
13 TCGA Pancreatic Adenocarcinoma 0.4690 0.1090 1.1e-03 -0.004 0.046 0.079 NA 0.058 5.3e-01 5.3e-03 3.2e-04 NA 1.9e-03
14 TCGA Testicular Germ Cell Tumors 0.1610 0.0890 6.4e-03 0.039 0.076 0.034 NA 0.070 1.6e-02 1.2e-03 2.3e-02 NA 1.8e-03

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14
Bipolar Disorder (2018) 2.4 3.9 8.5 -2.9 0.1 -2.9 0.0 -2.7 1.3 -0.5 -2.8 0.0 -1.9 -2.0 -2.8 -0.5 -2.1
Bipolar Disorder or Schizophrenia 1.8 4.3 10.0 -3.2 0.5 -3.1 0.0 -3.0 -0.6 -0.0 -3.0 0.0 -1.5 -2.3 -3.1 0.4 -2.0
Depressed Affect (Nagel 2018) 1.0 2.1 6.5 0.9 -1.2 1.6 1.3 1.0 1.6 1.3 1.0 1.6 0.3 2.3 1.4 0.6 2.5
Depression (Nagel 2018) 0.4 0.7 3.0 0.2 -1.0 0.5 0.2 0.2 0.8 -0.2 0.1 1.6 -0.1 1.7 0.2 0.1 1.3
Intelligence (Savage-Jansen 2018) 0.3 1.1 2.7 -1.0 0.0 -1.2 -0.7 -1.2 -0.7 0.2 -1.0 -0.9 1.0 -1.6 -1.0 1.2 -1.4
Neuroticism (Nagel 2018) 0.6 1.4 4.8 0.4 -0.1 1.6 1.0 0.6 0.9 1.1 0.5 1.6 0.9 1.7 1.3 0.7 2.2
Schizophrenia (2018) 0.8 1.6 3.3 -1.8 0.8 -1.6 0.0 -1.7 -1.8 0.4 -1.6 0.0 -0.4 -1.3 -1.7 0.9 -0.9
Schizophrenia vs Biploar Disorder 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.6 0.0 0.0 -0.4
Worry (Nagel 2018) 0.6 1.3 3.3 0.6 1.3 1.7 1.3 1.0 -0.3 0.2 0.9 0.8 1.0 1.8 1.3 -0.1 1.8
Alzheimer’s Disease (in mother) 0.8 0.9 2.4 0.9 -0.5 0.9 1.3 1.1 0.7 -0.4 1.0 0.9 -0.4 1.5 0.9 0.1 1.6
Alzheimer’s Disease (in father) 2.1 2.3 5.1 2.1 0.4 1.7 1.6 1.7 -0.0 0.9 1.8 1.8 2.3 0.5 1.9 -1.5 0.8
Alzheimer’s Disease (including proxy) 2.5 3.6 6.8 2.4 -0.3 2.4 2.4 2.6 0.7 0.2 2.6 1.6 1.7 1.6 2.5 -0.5 2.1
Crohns Disease (2017) 0.3 0.6 2.9 0.4 -0.5 0.3 0.9 0.5 0.5 1.7 0.3 0.5 0.9 1.1 0.4 1.1 -0.4
Irritable Bowel Disease (IBD) 0.2 0.4 2.8 0.1 -0.6 0.1 0.3 -0.0 -0.2 1.7 -0.1 -0.4 0.8 0.1 0.5 0.2 -1.1
Ulcerative Colitis (UC) 0.4 0.7 2.7 -0.4 -0.3 -0.2 -0.7 -0.8 -1.1 0.9 -0.8 -1.0 0.2 -0.9 0.1 -1.0 -1.6
Major Depression (MDD) 0.3 0.4 3.0 0.6 0.6 0.6 0.5 0.4 0.5 -0.4 0.4 1.7 0.6 0.0 0.3 0.2 0.2
Reaction Time 1.8 3.5 7.7 -2.8 -1.2 -2.5 -2.4 -2.7 -0.2 0.2 -2.7 0.8 -1.3 -1.0 -2.6 0.6 -1.4
Verbal and Numeric Reasoning (VNR) 0.2 0.6 2.6 -0.0 0.1 -0.3 0.4 -0.0 -0.5 1.1 0.1 -1.2 1.6 -1.0 -0.0 0.8 0.6
Breast Cancer 2.4 5.7 19.0 2.4 0.6 2.7 2.6 2.4 -0.3 2.8 2.5 1.2 4.4 1.8 3.1 0.9 2.3
Ovarian Cancer 1.2 1.6 4.5 -1.9 -0.8 -1.1 -1.6 -1.6 -1.0 0.6 -1.6 -2.1 -0.6 -1.1 -1.1 -0.5 0.5
Prostate Cancer 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
Age at First Birth 0.2 0.3 3.0 -0.3 0.3 0.1 -0.4 -0.0 1.7 0.1 -0.0 0.0 0.3 -0.4 0.1 1.0 -0.4
Bipolar Disorder (2011) 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0
Body Mass Index (BMI) (2010) 0.2 0.2 1.9 0.2 -0.0 0.4 0.4 0.3 -0.5 0.3 0.3 0.0 -0.3 0.1 0.4 -1.4 -0.2
Coronary Artery Disease (CAD) 1.2 1.5 5.0 -1.6 -0.4 -1.4 0.0 -1.5 -2.1 0.8 -1.4 0.0 0.3 -2.2 -1.1 0.0 -0.3
Crohns Disease (2012) 0.2 0.4 1.1 -0.7 -0.1 -1.0 0.0 -0.6 0.6 1.0 -0.6 0.0 0.1 -0.3 -0.9 0.3 -1.1
Mean Putamen Volume 2.0 2.3 6.1 1.5 0.4 1.7 1.7 1.4 0.1 2.5 1.4 0.5 1.9 1.5 1.7 0.9 1.9
Fasting Glucose 0.4 0.5 1.1 -0.6 -1.1 -1.1 -0.5 -0.6 -0.1 -0.9 -0.5 0.6 -0.5 -0.5 -0.7 -1.0 -0.7
HbA1C 0.5 0.6 1.9 0.8 -0.8 0.7 0.5 0.7 0.2 -0.3 0.6 0.4 -0.5 0.9 0.9 -1.3 1.4
HDL Cholesterol 0.4 0.6 3.7 0.5 -0.7 0.6 0.2 0.3 -1.0 0.8 0.5 0.0 1.9 -0.6 0.8 0.1 0.7
LDL Cholesterol 0.3 0.4 2.0 0.3 1.4 0.1 0.1 0.4 -0.3 1.2 0.5 0.0 1.2 -0.0 0.5 -0.5 -0.3
Lupus 0.9 1.4 5.1 -1.3 0.9 -0.7 -1.1 -1.1 0.4 1.6 -1.1 -0.9 0.8 -2.2 -0.6 -1.6 -0.3
Neuroticism (2016) 0.8 1.2 4.4 1.0 -0.2 1.0 1.2 0.9 -0.4 -0.2 0.9 1.7 -0.1 1.8 0.8 0.2 2.1
Primary Biliary Cirrhosis 0.2 0.3 2.6 0.1 -0.9 -0.1 0.1 0.1 0.4 -0.7 0.1 0.0 -0.1 0.7 0.1 -1.6 -0.3
Rheumatoid Arthritis 0.9 1.3 3.3 -1.8 0.1 -1.2 0.0 -1.7 -1.0 -0.2 -1.6 -1.4 -0.2 -1.7 -1.3 -0.1 -0.3
Schizophrenia (2014) 1.3 3.0 7.5 -2.6 0.2 -2.5 0.0 -2.5 -2.0 0.1 -2.4 0.0 -0.7 -1.4 -2.7 -0.3 -1.5
Triglycerides 0.3 0.5 1.6 -0.6 0.5 -0.7 -0.7 -0.4 1.3 -0.9 -0.5 0.0 -1.2 -0.1 -0.7 0.3 -0.7
Type 2 Diabetes (T2D) (2012) 0.4 0.5 2.3 0.5 -0.2 0.7 0.0 0.5 -1.0 0.5 0.6 0.0 1.3 0.1 0.8 0.0 1.5
Ulcerative Colitis 0.7 1.0 8.0 -0.8 -0.1 -0.4 0.0 -0.8 -2.8 0.1 -0.8 0.0 0.5 -1.4 -0.2 -0.3 -1.5
Blood Eosinophil Count 0.0 0.2 0.7 -0.2 0.8 -0.2 -0.5 -0.2 0.6 -0.2 -0.2 -0.3 0.8 -0.2 0.4 -0.2 -0.8
Blood Platelet Count 0.1 1.1 3.1 1.0 -1.8 1.2 0.9 0.9 1.1 0.5 0.9 0.8 1.5 0.7 1.0 0.8 -0.5
Blood Red Count 1.3 12.8 39.3 -4.3 0.1 -4.3 -4.1 -4.3 -2.2 2.1 -3.9 -0.6 0.9 -6.3 -3.6 0.5 -5.3
Blood White Count 0.1 0.4 1.5 0.8 0.7 0.8 0.5 0.9 -0.5 0.3 0.9 0.3 1.2 0.1 0.6 0.1 0.0
Heel T-Score 0.8 6.0 18.8 2.2 -0.5 1.9 1.1 1.9 -4.3 1.7 2.2 -4.3 3.6 -1.9 2.2 1.9 1.0
BMI 0.2 1.1 3.2 1.4 -1.8 0.8 1.1 1.3 0.4 1.5 1.4 -0.1 0.9 0.0 1.0 0.6 0.5
Height 0.3 5.9 12.0 -3.0 0.5 -3.3 -2.8 -3.2 -1.9 -2.1 -3.5 -1.5 -1.9 -1.4 -3.3 -1.9 -1.4
Waist Hip Ratio (WHR) 0.5 2.3 4.6 -2.1 -0.5 -1.9 -1.9 -1.9 -0.9 -1.9 -1.9 -1.1 -1.0 -0.7 -1.8 -1.3 -0.9
Systolic Blood Pressure 0.1 0.6 1.9 0.8 0.5 1.2 0.6 0.6 0.6 -0.4 0.6 0.8 -0.2 0.7 0.9 1.4 -0.5
Smoking Status 0.2 0.4 4.7 -0.4 -0.4 -0.4 -0.3 -0.4 -0.2 -0.1 -0.5 0.2 -0.2 0.1 -0.5 -2.2 0.2
Allergy or Eczema 0.5 1.3 2.9 -1.3 -0.2 -1.1 -1.5 -1.2 -0.6 1.0 -1.1 -1.6 0.6 -1.7 -1.3 -0.5 -1.0
Cardiovascular Disease 0.5 1.5 4.9 0.9 -2.2 1.0 1.3 0.8 1.3 0.7 0.8 1.6 -1.1 1.8 0.8 0.6 1.2
Hypothyroidism (self reported) 0.4 1.0 4.8 0.8 -2.2 1.0 0.6 0.8 0.7 -0.1 0.8 0.2 -0.0 1.3 0.7 1.2 1.2
Respiratory disease 0.2 0.3 2.0 0.4 -0.4 0.1 -0.1 0.1 0.8 0.1 0.1 -0.8 0.2 -0.5 0.0 -0.9 -1.4
Type 2 Diabetes (T2D) (2018) 0.3 0.6 1.6 -1.3 -0.2 -0.4 -0.9 -1.1 -0.9 1.1 -1.1 -0.5 -0.0 -0.2 -0.5 -0.1 0.5
Lung FEV1/FVC ratio 0.4 2.0 5.3 -1.7 -1.3 -2.3 -1.5 -1.8 -0.6 0.1 -1.6 0.5 -0.3 -2.0 -2.1 0.4 -0.8
Lung FVC 0.3 1.4 3.4 1.1 -0.7 1.4 1.2 1.3 -1.1 1.4 1.5 0.7 1.9 -0.4 1.7 0.0 0.7
Neuroticism 0.5 1.2 3.1 0.8 0.9 1.4 1.2 0.9 0.1 1.8 0.8 0.7 1.1 0.9 1.4 0.4 1.7
Chronotype (morning person) 0.9 2.2 7.7 -0.5 2.2 -0.9 -1.2 -0.9 -0.0 1.2 -0.9 -2.1 0.3 -2.8 -0.3 1.4 -2.3
Hair Pigment 0.1 2.3 10.1 1.1 0.9 1.2 0.7 1.0 -1.0 2.4 1.2 -1.4 3.2 -1.5 2.0 0.8 0.2
Tanning 0.1 0.8 5.1 0.3 -0.9 0.6 0.2 0.6 -0.9 -2.3 0.5 -1.1 -0.8 0.9 0.4 -0.5 -0.3
Hand grip strength (left) 0.1 0.3 1.2 0.6 0.3 -0.0 0.5 0.4 0.2 0.8 0.4 -0.3 1.1 -0.5 0.2 -0.5 0.4
Number of treatments/medications taken 0.3 0.5 1.8 -0.8 -1.3 -0.7 -0.3 -0.4 -0.7 -0.4 -0.5 0.3 -1.4 0.6 -0.8 -0.0 0.1
Average weekly spirits intake 0.8 1.0 2.8 1.5 -0.2 1.3 0.9 1.1 0.3 -1.1 1.1 -0.7 0.1 0.7 1.1 1.7 -0.6
Sensitivity / hurt feelings 0.2 0.3 1.5 -0.1 0.3 0.7 0.1 -0.0 -0.8 0.1 -0.1 -0.4 0.1 -0.5 0.7 1.2 0.0
Frequency of depressed mood in last 2 weeks 0.5 0.7 2.0 -0.2 -1.4 -0.6 -0.2 -0.4 0.6 -0.5 -0.5 1.4 -1.3 1.4 -0.7 -0.1 0.6
Hearing difficulty/problems: Yes 1.0 1.6 5.2 -0.9 0.8 -1.0 -1.2 -1.1 -2.3 -1.9 -1.1 -1.0 1.1 -1.9 -0.8 1.0 0.4
Relative age of first facial hair 1.1 2.2 4.2 1.8 0.8 2.0 1.6 1.9 1.0 1.1 2.0 -0.2 0.6 1.6 1.8 0.2 1.9
Other serious medical condition/disability diagnosed by doctor 0.7 0.9 5.1 0.8 -0.9 0.5 0.7 0.7 1.0 -1.0 0.5 -0.1 -1.4 2.3 0.2 0.8 0.0
Ever used hormone-replacement therapy (HRT) 1.0 1.2 2.9 -1.7 0.2 -1.5 -1.0 -1.6 -1.1 0.3 -1.6 -0.4 -1.1 -0.4 -1.6 -0.5 -0.2
Ever had hysterectomy (womb removed) 0.9 1.0 3.7 0.1 -0.8 0.1 0.6 0.1 1.9 -0.2 -0.1 1.4 -1.9 1.7 -0.2 -1.0 0.3
Systolic blood pressure, automated reading 0.1 0.4 2.3 0.0 -0.3 0.6 -0.1 0.0 1.2 -0.6 0.0 1.5 -0.1 -0.4 0.6 -0.8 -0.2
Eye problems/disorders: Diabetes related eye disease 0.3 0.4 1.9 0.5 -0.2 0.3 0.5 0.6 -1.4 0.7 0.6 0.1 1.0 -0.1 0.6 -0.3 0.1
Angina 0.2 0.3 1.4 0.2 -0.0 0.5 0.6 0.5 0.5 1.0 0.3 1.2 0.5 0.2 0.5 0.1 0.4
Medication for hormone replacement therapy 0.4 0.5 1.8 0.7 0.5 0.7 0.8 0.7 0.6 0.2 0.6 -0.5 1.3 0.7 0.6 0.8 0.5
Vitamin and mineral supplements 2.2 2.9 7.5 2.1 0.1 2.5 2.0 2.1 0.3 -0.2 2.1 1.9 0.9 1.8 2.7 -0.6 1.5
Supplements: Zinc 0.4 0.4 2.2 0.4 -0.3 -0.3 0.2 0.3 1.0 1.5 0.3 -0.5 0.6 -0.2 -0.2 0.5 -1.0
Medication: Co-codamol 0.9 1.1 2.7 1.1 -1.0 1.0 0.7 1.1 -1.1 -1.6 1.0 -0.1 -0.7 0.6 0.8 -1.6 1.1
Medication: Metformin 0.3 0.4 1.5 0.1 -1.2 0.2 0.3 0.2 0.3 1.2 0.2 -0.8 0.3 0.9 0.3 -0.8 0.6
Diabetes (father) 0.3 0.3 2.4 0.4 -0.2 -0.2 -0.2 0.0 -0.3 -0.4 -0.1 -0.2 -0.6 -0.2 -0.2 -1.5 -1.1
Diabetes (mother) 1.6 2.1 5.8 -1.8 0.5 -1.7 -1.7 -1.7 0.3 1.0 -1.7 0.9 -2.4 -0.1 -2.0 -1.5 -0.6
Severe depression (siblings) 0.4 0.5 1.1 -0.7 0.0 -0.5 -0.6 -0.8 -0.8 0.5 -0.7 -0.5 1.0 -0.9 -0.2 1.0 -0.9
Pack years adult smoking proportion 1.9 2.9 5.8 2.4 0.6 2.0 2.2 2.1 0.4 0.8 2.2 1.9 -0.4 2.0 2.1 -1.6 1.1
Impedance of leg (right) 0.1 0.3 1.3 -0.4 0.2 -0.2 -0.1 -0.3 0.7 -0.8 -0.4 0.6 -0.5 1.1 -0.3 -0.3 0.1
Leg fat-free mass (left) 0.1 0.6 3.2 -0.4 -0.2 -0.8 -0.3 -0.6 -1.0 0.6 -0.6 -1.8 -0.3 -1.0 -0.6 0.6 0.3
Trunk fat percentage 0.4 1.5 6.6 1.2 -2.6 0.8 1.4 1.3 0.1 0.5 1.4 0.6 0.3 1.2 0.9 -0.7 1.7
Hand grip strength (right) 0.1 0.3 1.1 0.4 0.4 0.3 0.2 0.3 1.0 0.1 0.3 -0.0 0.7 -0.4 0.3 -1.0 0.3
Townsend deprivation index at recruitment 5.2 7.3 12.3 3.4 -1.0 3.5 3.4 3.4 1.8 1.6 3.4 1.6 1.2 3.0 3.5 0.7 3.4
Current tobacco smoking 0.3 0.5 2.1 0.4 -0.0 0.3 0.5 0.4 -0.6 0.0 0.4 0.4 -0.7 1.4 0.2 -1.3 0.7
Average weekly fortified wine intake 0.6 0.7 1.9 -0.8 0.3 -0.7 -0.8 -0.6 -1.1 -1.0 -0.8 0.6 -0.9 -1.0 -0.6 -0.8 -1.4
Maternal smoking around birth 0.3 0.5 2.2 0.1 -1.5 0.6 -0.4 -0.2 -0.2 -1.3 -0.1 0.7 -0.1 0.7 0.2 0.9 0.5
Fed-up feelings 0.7 1.3 2.8 1.2 0.1 1.3 1.3 1.1 0.9 1.0 1.2 1.1 -0.0 1.7 1.2 0.9 1.6
Frequency of unenthusiasm / disinterest in last 2 weeks 0.8 1.1 4.8 0.8 -1.2 0.8 0.9 0.9 0.4 0.4 0.8 2.2 0.2 1.5 0.5 -1.0 1.4
Relative age voice broke 1.0 1.6 2.8 1.3 -1.1 1.5 1.3 1.5 1.5 1.2 1.5 0.1 1.0 1.1 1.7 0.5 1.3
Taking other prescription medications 0.3 0.4 1.9 0.3 -1.4 0.3 0.3 0.3 0.6 -1.0 0.3 0.5 -0.9 1.1 -0.0 0.4 0.5
Age when periods started (menarche) 0.5 1.3 8.6 -1.2 0.7 -1.4 -0.7 -0.8 0.0 2.9 -0.8 -0.5 0.2 -1.2 -1.0 -1.1 -0.2
Bilateral oophorectomy (both ovaries removed) 0.2 0.2 0.6 0.5 0.4 0.8 0.8 0.4 0.1 0.2 0.3 0.1 -0.2 0.7 0.5 -0.4 -0.1
Heel bone mineral density (BMD) T-score, automated (left) 0.7 1.7 5.0 0.8 0.3 1.3 0.7 0.7 -2.2 0.1 0.9 -2.1 1.7 -1.0 1.3 1.3 1.5
Tinnitus: Yes, but not now, but have in the past 0.4 0.4 1.1 -1.0 -0.2 -0.8 -0.8 -0.8 0.3 0.1 -0.8 0.6 -0.3 -0.3 -0.6 0.9 -0.1
Qualifications: CSEs or equivalent 0.5 0.7 3.2 -0.1 0.1 -0.7 -0.6 -0.2 -1.8 -1.1 -0.3 -0.5 -1.2 0.2 -0.7 -1.0 -1.0
Serious illness, injury or assault to yourself 0.8 0.9 3.2 -0.9 -0.9 -1.0 -1.0 -0.8 0.4 -0.5 -1.0 0.1 -1.8 -0.5 -1.1 0.7 -1.4
High blood pressure 0.3 1.0 3.3 -0.1 -1.7 0.1 0.3 0.1 0.0 -0.1 0.0 1.4 -1.7 1.8 0.0 -1.3 0.8
Hayfever, allergic rhinitis or eczema 0.9 2.0 5.3 -1.8 0.3 -1.5 -2.1 -1.8 -0.2 0.7 -1.7 -1.2 0.5 -2.3 -1.5 0.7 -1.4
Multivitamins +/- minerals 1.8 2.2 6.3 -1.6 -0.4 -2.4 -1.5 -1.7 0.4 0.5 -1.7 -0.2 -1.7 -1.7 -2.5 0.1 -1.7
Stomach or abdominal pain in last month 1.5 1.9 4.5 -1.5 -1.0 -1.6 -1.4 -1.8 -0.8 -0.7 -1.9 0.7 -2.1 -0.6 -1.9 -1.3 -0.8
Supplements: Glucosamine 0.1 0.2 0.9 -0.1 1.0 -0.8 0.2 -0.0 -0.4 0.1 -0.1 -0.1 0.4 -0.4 -0.6 -0.1 -0.3
Diverticular disease/diverticulitis (self-reported) 0.3 0.3 2.7 0.0 -1.6 -0.3 -0.1 -0.1 -0.1 0.8 -0.1 0.1 0.1 0.1 -0.5 -0.8 0.0
Medication: Atenolol 1.7 2.1 6.4 -1.3 -2.0 -1.7 -1.1 -1.1 -1.4 -1.5 -1.3 0.9 -2.5 0.5 -1.6 -1.1 -1.1
Medication: Levothyroxine sodium 0.2 0.4 1.3 0.3 -0.8 0.3 0.1 0.5 -0.9 -1.1 0.4 0.7 -0.7 0.8 0.1 -0.5 0.8
Sitting height 0.2 1.5 4.9 -1.3 0.5 -1.4 -1.1 -1.5 -1.0 0.5 -1.6 -2.2 -1.4 -1.2 -1.4 0.0 0.0
Chronic bronchitis/emphysema (father) 0.2 0.3 1.0 -0.4 -0.7 -0.0 -0.2 -0.2 -0.7 0.6 -0.1 0.7 0.9 -0.1 0.0 -1.0 0.4
High blood pressure (mother) 0.3 0.5 2.6 -0.4 0.6 -0.1 -0.3 -0.4 -1.5 0.3 -0.3 -1.6 -0.2 -0.2 -0.1 0.7 0.3
Body mass index (BMI) 0.4 1.9 4.3 2.0 -2.1 1.5 1.5 1.8 0.5 0.6 1.9 -0.1 0.8 0.8 1.7 -0.3 1.5
Impedance of leg (left) 0.1 0.5 3.3 0.2 -0.1 0.3 0.4 0.3 1.2 -0.7 0.2 1.0 -0.6 1.8 0.1 -0.3 0.6
Leg predicted mass (left) 0.1 0.6 3.3 -0.4 -0.1 -0.7 -0.3 -0.5 -1.1 0.7 -0.6 -1.8 -0.3 -1.0 -0.6 0.6 0.2
Trunk fat mass 0.2 1.0 3.7 1.2 -1.9 0.7 1.2 1.2 0.0 0.5 1.2 -0.1 0.4 0.8 0.8 -0.6 1.5
Waist circumference 0.2 0.8 3.1 0.9 -1.8 0.6 0.9 0.9 -0.6 0.1 0.8 -0.8 0.5 0.8 0.8 -0.7 1.3
Number of incorrect matches in round 0.2 0.4 1.2 -0.1 -0.6 -0.2 -0.3 -0.1 1.1 0.6 -0.2 1.0 -0.4 0.8 -0.4 0.2 1.1
Past tobacco smoking 0.5 1.0 5.9 -0.3 0.2 -0.5 -0.4 -0.4 0.3 -0.5 -0.4 0.6 -2.1 1.0 -0.8 2.4 0.2
Alcohol usually taken with meals 1.2 1.9 4.0 -1.9 -0.9 -1.9 -1.7 -1.8 -0.6 -0.3 -1.8 -0.4 0.3 -1.5 -2.0 1.0 -1.3
Nervous feelings 0.8 1.4 6.3 0.8 -0.9 1.6 1.3 1.0 0.7 -0.8 1.0 2.5 0.5 1.7 1.3 -0.4 0.5
Frequency of tenseness / restlessness in last 2 weeks 0.6 0.9 1.9 1.1 -0.9 0.9 1.0 1.0 -0.3 0.3 0.8 1.2 -0.1 1.4 0.7 -1.1 1.4
Hearing difficulty/problems with background noise 0.7 1.1 3.6 -0.8 -0.1 -1.1 -0.8 -1.0 -1.7 -1.9 -1.0 -0.0 -0.2 -1.4 -1.0 -0.7 0.6
Hair/balding pattern: Pattern 2 0.9 1.1 2.6 1.4 -0.5 1.0 1.3 1.3 -0.7 -1.6 1.3 0.1 1.5 0.9 0.9 -0.0 -0.0
Had menopause 0.6 0.7 3.2 0.2 1.8 0.7 0.6 0.5 -0.8 0.6 0.5 -1.1 0.9 -0.0 1.0 -0.9 0.9
Had other major operations 0.2 0.2 1.1 -0.0 -0.4 -0.2 -0.3 -0.2 0.4 -0.1 -0.2 1.0 -0.6 0.5 -0.2 -0.1 -0.7
Forced vital capacity (FVC) 0.1 0.4 2.0 -0.0 0.4 -0.2 0.1 -0.3 -1.4 0.9 -0.2 -0.3 0.8 -0.7 -0.2 0.9 0.7
Heel bone mineral density (BMD) T-score, automated (right) 0.6 1.4 4.4 0.8 0.6 1.2 0.7 0.8 -2.1 0.4 0.9 -1.6 1.7 -0.8 1.1 1.4 1.1
Ever unenthusiastic/disinterested for a whole week 0.9 1.1 2.8 -1.1 -1.7 -0.9 -1.4 -1.1 1.4 0.1 -1.1 -0.1 -0.5 -0.8 -1.0 0.6 -1.6
Qualifications: None of the above 0.1 0.2 0.5 0.0 -0.4 0.0 0.4 -0.0 0.3 -0.3 -0.1 0.7 -0.4 0.7 -0.1 0.5 0.6
Financial difficulties in last 2 years 0.3 0.3 1.3 0.6 -0.6 0.7 0.5 0.4 -0.3 0.6 0.5 0.6 1.2 0.2 0.7 0.5 0.3
Mouth/teeth dental problems 0.5 0.8 3.0 -0.6 -0.7 -0.8 -1.0 -0.9 -1.7 0.3 -0.9 -0.1 0.3 -1.1 -0.5 0.6 -1.3
Heart attack 1.5 1.9 5.0 1.6 0.1 1.5 1.8 1.9 0.6 -0.1 1.8 0.9 0.5 1.3 1.6 0.6 2.2
Allergy 0.6 1.3 5.4 0.9 -0.6 1.0 1.4 1.0 0.4 -0.8 0.9 1.2 -1.1 2.3 0.9 -0.2 1.6
Pain all over the body in last month 0.6 0.7 3.0 -0.3 -1.7 -0.5 0.2 -0.3 -0.3 0.6 -0.3 1.6 -0.9 1.1 -0.5 1.0 0.2
Diabetes (self-reported) 0.3 0.5 3.1 -0.4 -1.1 -0.2 0.1 -0.4 1.1 1.8 -0.4 -0.1 0.9 0.5 0.1 -0.1 0.5
Hayfever/allergic rhinitis (self-reported) 0.5 0.6 2.6 -0.8 0.3 -0.5 -1.1 -0.8 -0.7 -0.2 -0.8 -1.6 0.1 -0.8 -0.4 -0.4 -0.9
Medication: Ramipril 0.2 0.2 1.5 0.0 0.3 -0.1 0.4 0.3 -1.2 -0.1 0.3 0.7 0.1 0.4 0.0 -0.5 0.2
Medication: Simvastatin 0.4 0.6 3.0 0.5 0.4 0.2 1.0 0.5 0.7 1.7 0.5 1.2 0.2 0.1 0.5 -0.8 0.4
Fluid intelligence score 0.2 0.5 1.7 -0.7 -1.0 -0.6 -0.3 -0.7 -0.2 -0.1 -0.6 -0.3 1.3 -1.3 -0.5 0.5 -0.4
Illnesses of siblings 0.3 0.4 1.5 0.2 0.5 -0.1 0.3 0.3 0.9 0.8 0.2 0.6 1.2 -0.1 0.2 1.1 -0.4
Neuroticism score 0.2 0.4 1.2 0.6 0.1 0.7 0.7 0.4 0.2 0.2 0.3 1.1 0.4 0.7 0.8 0.6 0.8
Weight 0.1 0.5 1.8 0.9 -1.3 0.4 0.8 0.7 -0.0 0.6 0.7 -1.2 0.1 0.2 0.5 -0.1 1.1
Impedance of arm (right) 0.3 1.4 3.7 -1.7 -0.3 -1.8 -1.1 -1.5 -0.5 -0.2 -1.5 1.3 -1.3 0.1 -1.9 -0.0 -0.4
Arm fat percentage (right) 0.3 1.2 6.1 1.1 -2.5 0.6 1.0 1.2 -0.1 0.0 1.2 0.5 0.0 1.1 0.7 -0.6 1.6
Trunk fat-free mass 0.1 0.8 7.0 -0.4 0.8 -0.5 -0.4 -0.7 -0.6 -0.0 -0.8 -2.6 -0.2 -1.1 -0.4 0.7 -0.4
Hip circumference 0.2 0.9 2.1 1.4 -1.3 0.8 1.1 1.1 -0.4 0.4 1.1 -0.8 0.6 0.5 0.9 0.9 1.4
Time employed in main current job 1.5 1.7 6.4 1.7 1.2 1.5 1.0 1.5 2.5 -1.0 1.5 0.6 0.3 1.3 1.4 0.5 0.7
Alcohol intake versus 10 years previously 0.3 0.4 1.0 -0.2 -0.8 -0.3 -0.5 -0.6 -0.9 0.6 -0.5 -0.3 -0.5 -1.0 -0.1 -1.0 -0.6
Father’s age at death 0.3 0.4 1.4 -0.5 0.7 -0.1 -0.5 -0.5 -0.5 0.7 -0.4 -0.6 -0.0 -0.4 -0.3 1.0 1.2
Worrier / anxious feelings 0.2 0.4 2.3 0.2 1.5 0.2 0.2 0.1 -0.7 -0.8 0.0 0.3 0.8 -0.1 0.5 -0.1 -0.6
Frequency of tiredness / lethargy in last 2 weeks 0.7 1.2 7.2 0.6 -2.0 0.4 0.7 0.6 0.6 0.8 0.5 1.4 0.1 1.1 0.3 -0.2 2.7
Falls in the last year 1.3 1.7 7.6 -0.6 -0.2 -0.6 -1.3 -0.7 -1.9 -2.8 -0.9 -1.4 -2.0 -0.2 -1.1 -0.4 -1.2
Hair/balding pattern: Pattern 3 0.7 1.0 2.2 0.6 0.0 1.3 1.2 1.1 0.1 1.2 1.1 0.9 0.1 1.5 1.0 -0.8 1.4
Number of live births 0.3 0.4 2.2 0.2 -0.6 0.3 0.7 0.4 0.5 0.5 0.3 0.5 -0.3 1.0 0.2 0.7 1.5
Forced expiratory volume in 1-second (FEV1) 0.1 0.5 1.9 -0.2 0.2 -0.4 -0.1 -0.4 -1.1 1.4 -0.3 -0.1 0.8 -1.0 -0.4 0.9 0.9
Pulse rate 0.7 1.2 3.2 -1.1 -0.4 -1.0 -1.1 -1.1 0.8 -1.6 -1.2 -1.8 -0.2 -0.9 -1.0 -0.3 -1.2
Happiness 0.6 0.8 2.5 0.9 0.4 0.9 0.8 0.7 0.4 1.6 0.8 -0.6 0.2 0.9 1.0 -0.7 1.4
Noisy workplace 0.4 0.4 3.2 0.2 0.3 0.1 -0.2 0.2 -0.3 -1.8 0.0 -0.6 -0.2 0.8 -0.0 -1.3 0.2
Qualifications: A levels/AS levels or equivalent 1.0 2.2 9.2 1.2 1.1 1.8 1.5 1.5 3.0 -0.5 1.6 -0.0 1.1 1.4 1.7 0.3 1.5
Serious illness, injury or assault of a close relative in last 2 years 0.5 0.6 2.5 1.0 0.4 0.5 0.7 0.8 -0.1 1.6 0.8 -0.1 0.4 0.2 0.7 -1.3 -0.7
Mouth/teeth dental problems: Dentures 0.7 1.2 3.6 1.2 -0.3 0.7 1.5 1.4 0.5 -1.0 1.4 0.3 -0.1 1.9 0.6 -0.9 1.7
Asthma 1.0 2.0 4.3 -1.6 -0.8 -1.8 -1.7 -1.7 -0.6 -0.7 -1.7 -0.9 -0.5 -1.8 -1.8 -0.5 -2.1
Medication: Ibuprofen (e.g. Nurofen) 0.5 0.7 4.7 -0.0 -0.2 -0.3 -0.2 -0.3 -0.7 2.2 -0.2 1.6 -0.4 0.0 -0.5 0.8 0.5
Medication: Cholesterol lowering 0.2 0.3 1.1 0.1 1.0 0.2 0.4 0.3 0.1 0.9 0.3 0.6 -0.2 0.2 0.4 -1.0 0.1
Depression (self-reported) 1.1 1.3 10.2 0.3 -3.2 0.4 0.1 0.1 1.9 -1.0 0.2 0.8 0.2 0.9 0.3 -0.0 1.0
Medication: Lansoprazole 0.2 0.2 1.1 0.6 -1.1 0.1 0.5 0.3 -0.8 -0.1 0.4 -0.1 0.5 0.1 0.1 -0.3 0.0
Prospective memory result 1.2 1.5 3.6 1.4 0.7 1.3 1.2 1.6 1.1 1.4 1.5 0.6 0.2 1.9 1.1 -0.2 1.2
Lung cancer (father) 0.8 0.9 4.5 0.1 -2.1 0.1 0.2 -0.0 1.8 0.6 0.0 2.1 0.5 -0.2 0.3 0.3 0.6
Illnesses of mother 0.5 0.6 1.8 -0.5 -0.2 -0.6 -0.5 -0.5 0.4 0.2 -0.4 1.3 1.0 -1.1 -0.7 -0.2 -1.3
Forced expiratory volume in 1-second (FEV1), Best measure 0.1 0.3 1.2 -0.3 -0.3 -0.4 -0.3 -0.5 -0.5 1.1 -0.4 0.1 0.4 -0.6 -0.5 0.5 0.5
Pulse wave Arterial Stiffness index 0.8 0.9 7.9 -0.6 -2.8 -0.7 -0.6 -0.7 0.6 0.3 -0.7 0.9 0.0 -0.8 -0.5 -0.7 0.6
Impedance of arm (left) 0.3 1.2 2.8 -1.6 -0.0 -1.5 -0.9 -1.3 0.2 0.2 -1.3 1.7 -1.1 0.0 -1.6 -0.2 -0.7
Arm fat mass (right) 0.2 1.0 3.6 1.2 -1.9 0.8 1.1 1.1 0.2 0.3 1.2 -0.2 0.4 0.7 0.9 -0.4 1.5
Trunk predicted mass 0.1 0.8 7.0 -0.4 0.8 -0.6 -0.4 -0.7 -0.6 -0.1 -0.8 -2.6 -0.3 -1.1 -0.5 0.7 -0.4
Standing height 0.2 2.4 4.8 -1.9 1.6 -2.0 -1.2 -2.0 -0.8 -0.0 -2.2 -2.2 -1.2 -1.2 -2.0 0.6 -0.6
Length of working week for main job 1.2 1.3 2.7 1.3 0.2 1.2 0.8 1.2 -1.3 -0.4 1.2 -0.5 -0.8 1.4 1.2 1.6 1.4
Exposure to tobacco smoke at home 0.3 0.4 1.4 0.2 -0.4 0.7 0.5 0.3 0.3 0.7 0.3 -0.9 0.1 1.0 0.5 -0.5 1.2
Breastfed as a baby 0.5 0.6 3.0 -0.3 0.2 -0.3 0.4 0.1 -1.4 1.6 -0.0 -0.2 0.5 0.3 -0.4 -1.7 -0.1
Tense / ‘highly strung’ 1.0 1.7 2.9 1.6 -0.7 1.7 1.7 1.6 -0.5 0.7 1.5 0.3 1.7 1.3 1.7 0.5 1.3
Seen doctor (GP) for nerves, anxiety, tension or depression 0.3 0.4 2.1 0.5 -1.4 0.3 0.3 0.3 0.5 0.1 0.3 0.7 -1.2 0.7 0.1 -0.6 0.2
Hair/balding pattern: Pattern 4 0.8 1.9 3.5 1.5 1.6 1.5 1.4 1.6 0.2 -0.2 1.6 -1.9 1.5 1.1 1.7 0.2 1.4
Birth weight of first child 1.1 2.0 5.1 -1.6 -0.1 -1.8 -1.5 -1.7 -0.3 -1.6 -1.8 0.0 -1.5 -0.2 -1.8 2.3 -0.7
Peak expiratory flow (PEF) 1.9 4.4 9.8 -2.5 -0.5 -2.7 -2.6 -2.7 -3.1 0.8 -2.6 -0.4 -1.3 -2.5 -2.8 -1.2 -0.2
Pulse wave reflection index 0.6 0.7 2.4 0.6 -1.6 0.6 0.4 0.3 0.3 1.0 0.5 1.0 1.0 -0.8 0.7 -0.9 1.1
Ever highly irritable/argumentative for 2 days 0.6 0.8 2.5 1.0 -1.6 0.6 0.8 0.9 0.9 -0.7 0.9 1.0 0.0 1.2 0.6 0.2 0.8
Loud music exposure frequency 0.2 0.2 1.2 0.3 0.9 -0.4 0.4 0.3 -0.3 -0.1 0.4 -0.2 1.1 -0.3 -0.2 -0.6 -0.2
Qualifications: O levels/GCSEs or equivalent 0.2 0.3 1.0 0.6 0.2 0.4 0.3 0.5 0.3 -0.1 0.7 1.0 0.8 -0.9 0.6 -0.6 0.1
Mouth/teeth dental problems: Bleeding gums 0.7 0.9 2.0 0.6 -0.4 1.4 0.7 0.8 1.4 1.2 0.8 1.4 0.3 0.8 1.1 -0.7 1.1
Blood clot in the leg (DVT) 0.5 0.6 2.9 0.2 -0.3 0.2 0.2 0.2 0.1 1.6 0.4 0.2 1.7 -1.3 0.5 -1.2 0.0
Medication: Paracetamol 0.3 0.6 3.3 0.4 0.3 0.7 0.3 0.5 -1.8 0.5 0.4 -0.7 -0.2 0.5 0.6 0.4 1.5
Headache pain in last month 1.0 1.6 4.6 -1.1 0.3 -1.2 -1.2 -1.3 -1.2 2.1 -1.1 1.1 0.8 -2.0 -0.8 -0.1 -1.9
Medication for cholesterol, blood pressure or diabetes 0.3 0.6 2.9 0.9 -0.2 0.6 0.3 0.6 1.0 -0.9 0.5 -0.8 0.5 0.3 0.4 1.7 -0.3
Glaucoma (self-reported) 0.8 0.9 4.1 -0.5 1.6 -0.5 -0.6 -0.6 -0.7 -2.0 -0.6 -1.1 -0.5 -1.1 -0.5 1.2 0.3
Gout (self-reported) 0.5 0.7 4.7 0.5 0.1 1.1 0.5 0.5 0.9 0.2 0.6 -0.5 2.2 -0.8 1.0 -0.2 -0.1
Hypothyroidism/myxoedema (self-reported) 0.3 0.5 2.4 -0.3 -1.6 -0.4 -0.7 -0.3 -0.2 -0.8 -0.4 0.0 -1.4 0.8 -0.7 0.2 -0.2
Medication: Amlodipine 0.4 0.6 3.3 -0.6 0.6 -0.5 -0.3 -0.6 -0.8 -0.0 -0.6 -0.5 -0.8 -0.6 -0.5 -1.8 -0.9
Medication: Ventolin 100micrograms inhaler 0.8 1.1 2.5 -0.9 0.2 -1.4 -0.9 -1.1 -1.6 0.1 -1.1 0.8 -1.3 -0.7 -1.3 -0.4 -1.4
Birth weight 0.3 0.6 3.8 -0.2 0.5 -0.2 0.3 0.1 1.4 -2.0 -0.0 -1.1 0.2 0.4 -0.2 0.7 0.3
Chronic bronchitis/emphysema (mother) 0.4 0.5 3.2 -0.2 0.5 -0.0 -0.6 -0.4 -1.8 -0.9 -0.5 -1.2 -0.7 -0.1 -0.2 0.3 0.3
High blood pressure (siblings) 1.0 1.4 4.2 -1.3 -1.1 -1.3 -1.1 -1.4 -1.3 -0.5 -1.5 -0.5 -2.0 -0.1 -1.6 0.6 0.6
Forced vital capacity (FVC), Best measure 0.1 0.2 1.6 0.1 -0.4 0.1 0.2 -0.0 -0.5 1.3 0.1 0.1 0.6 -0.3 0.0 0.3 0.6
Body fat percentage 0.6 2.2 6.8 1.8 -2.6 1.2 1.8 1.8 0.3 0.5 1.8 0.7 0.3 1.7 1.3 -0.7 2.0
Leg fat percentage (right) 1.0 3.6 6.5 2.4 -2.5 1.9 2.2 2.4 0.9 0.8 2.3 0.7 0.6 2.5 2.1 -1.1 2.3
Arm fat-free mass (right) 0.1 0.6 6.5 0.5 0.1 0.4 0.5 0.3 0.1 0.2 0.2 -2.5 0.4 -0.4 0.5 0.5 0.4
Exposure to tobacco smoke outside home 0.4 0.5 1.2 0.5 -0.8 1.1 0.2 0.4 0.1 0.8 0.5 -0.5 1.0 -0.0 1.0 -0.3 1.1
Comparative body size at age 10 0.4 1.2 5.1 0.4 -1.5 0.9 0.2 0.5 1.4 -2.3 0.3 -1.7 -0.5 1.1 0.9 0.6 0.0
Number of full brothers 0.4 0.5 3.2 -0.1 0.6 0.3 -0.1 -0.1 0.9 -1.8 -0.1 -0.8 0.4 0.3 0.1 0.2 1.1
Worry too long after embarrassment 1.1 1.8 5.5 -1.7 0.9 -1.3 -1.6 -1.8 -0.0 0.4 -1.8 0.8 0.3 -2.3 -1.1 0.0 -1.9
Seen a psychiatrist for nerves, anxiety, tension or depression 0.4 0.5 1.5 -0.3 -1.0 -0.5 -0.2 -0.2 1.2 -1.0 -0.3 0.7 -0.7 0.7 -0.6 -0.4 -1.1
Wheeze or whistling in the chest in last year 0.9 1.5 2.7 -1.2 -1.0 -1.4 -1.3 -1.4 0.9 -1.0 -1.4 1.6 -1.6 -0.5 -1.5 0.5 -1.2
Number of children fathered 0.5 0.6 1.0 -0.9 -1.0 -0.5 -1.0 -1.0 -0.8 -0.6 -0.9 0.9 -0.9 0.1 -0.8 0.0 0.3
Reason for reducing amount of alcohol drunk: Health precaution 0.6 0.7 4.0 0.0 -0.4 -0.5 -0.4 -0.2 2.0 1.6 -0.3 -0.2 0.1 -0.5 -0.4 1.4 -0.4
Age at first live birth 0.9 1.6 3.6 -1.9 0.6 -1.4 -1.5 -1.8 -0.1 -0.4 -1.9 1.2 -0.7 -1.4 -1.6 0.7 -0.7
Pulse wave peak to peak time 0.8 1.0 8.8 0.3 3.0 0.4 0.5 0.4 -0.7 -0.3 0.4 -1.1 -0.3 0.7 0.2 0.9 -0.7
Health satisfaction 0.7 0.9 3.1 0.9 -1.8 0.8 0.3 0.5 1.0 -0.8 0.3 -0.0 -1.2 1.7 0.3 1.0 -0.0
Shortness of breath walking on level ground 1.1 1.3 3.7 1.4 -1.6 1.1 1.1 1.3 0.9 -1.3 1.3 0.5 0.3 1.9 0.9 0.7 0.6
Qualifications: College or University degree 0.1 0.4 2.9 -0.6 1.0 -0.3 -0.3 -0.4 0.4 -0.2 -0.4 -0.5 0.3 -0.3 -0.4 1.7 -0.4
Eye problems/disorders: None of the above 1.2 1.4 4.3 0.3 0.1 0.9 0.9 0.8 1.6 2.1 0.9 0.4 2.0 -0.2 1.1 0.8 2.0
Mouth/teeth dental problems: Loose teeth 0.6 0.7 2.4 1.0 0.2 0.8 1.2 1.0 0.5 -0.0 1.0 0.8 0.9 0.0 1.0 -1.5 0.2
Emphysema/chronic bronchitis 1.0 1.1 4.7 1.5 0.3 1.2 0.8 1.1 1.0 -0.0 1.1 2.2 0.1 1.0 1.1 -0.1 -0.6
Medication for pain relief, constipation, heartburn 0.8 1.3 4.1 1.0 1.8 1.1 0.3 0.8 2.0 -0.9 0.8 -0.7 1.3 -0.3 1.2 -1.5 -1.1
Neck or shoulder pain in last month 0.3 0.4 2.2 -0.1 -1.1 -0.2 -0.1 -0.3 -0.8 -0.5 -0.3 0.4 -0.0 0.5 -0.3 1.5 0.9
Medication: Blood pressure 0.7 1.2 3.7 -1.4 0.1 -1.2 -1.0 -1.1 -1.9 -0.7 -1.1 0.4 -1.1 -0.3 -1.1 -1.6 -0.1
Angina (self-reported) 0.4 0.5 1.5 0.5 0.0 0.7 0.8 0.7 0.4 1.1 0.6 1.2 0.7 0.2 0.8 0.2 0.5
Migraine (self-reported) 1.9 2.4 4.7 -2.0 0.4 -2.0 -1.9 -2.0 -0.9 0.1 -2.0 0.6 -1.2 -1.5 -2.2 -1.3 -1.7
Medication: Ibuprofen 0.4 0.5 1.3 -0.5 0.3 -0.7 -0.6 -0.6 -1.1 1.0 -0.6 1.0 -0.4 -0.1 -1.0 0.0 0.3
Medication: Allopurinol 0.9 1.2 6.9 0.6 0.3 1.1 0.8 0.7 0.6 0.8 0.8 -1.7 2.6 -0.4 1.2 -0.4 0.8
Medication: Omeprazole 1.3 1.6 4.9 -1.2 -0.2 -1.3 -1.3 -1.4 -0.0 0.0 -1.4 0.1 -0.6 -2.2 -1.4 1.5 -2.0
Medication: Seretide 50 evohaler 1.0 1.1 2.9 -1.3 0.6 -1.2 -1.4 -1.2 -1.3 0.5 -1.1 0.0 -0.5 -1.7 -1.1 0.0 -1.0
Mean time to correctly identify matches 1.1 2.0 4.6 -2.2 -1.5 -1.6 -1.5 -2.0 0.9 1.4 -2.0 1.2 0.1 -0.6 -1.7 -0.5 -1.0
Heart disease (mother) 0.5 0.6 2.6 -0.7 -0.9 -0.7 -0.8 -0.9 1.6 0.1 -0.9 0.2 -0.3 -0.4 -0.7 0.6 -0.8
Reproduciblity of spirometry measurement using ERS/ATS criteria 0.4 0.5 1.2 -0.6 -1.0 -0.7 -0.6 -0.7 -1.1 0.3 -0.7 -0.6 -1.1 -0.9 -0.5 -0.1 -0.3
Whole body fat mass 0.3 1.4 3.8 1.5 -1.9 1.0 1.4 1.5 0.2 0.4 1.5 -0.2 0.5 1.0 1.1 -0.4 1.8
Leg fat mass (right) 0.5 1.8 3.8 1.8 -1.8 1.3 1.6 1.7 0.5 0.5 1.7 0.0 0.2 1.4 1.4 -0.7 1.9
Arm predicted mass (right) 0.1 0.5 5.6 0.3 -0.1 0.2 0.3 0.1 0.1 0.2 0.0 -2.4 0.2 -0.4 0.3 0.5 0.2
Pulse rate, automated reading 0.6 1.8 4.8 -1.1 -0.2 -1.2 -1.2 -1.0 0.3 -1.8 -1.1 -2.2 0.0 -1.5 -0.9 -1.9 -2.0
Alcohol intake frequency. 0.2 0.5 2.6 0.2 -0.2 -0.3 -0.1 -0.2 -0.7 1.1 -0.0 1.6 -1.3 -0.7 -0.1 0.6 -0.2
Comparative height size at age 10 0.2 0.9 3.0 -0.3 1.1 -0.6 -0.3 -0.6 -1.7 -1.7 -0.8 -1.4 -0.3 -0.4 -0.8 -1.0 0.1
Number of full sisters 0.3 0.4 2.0 0.1 -0.7 -0.3 -0.5 -0.3 1.1 0.4 -0.3 0.1 -0.0 -0.6 -0.3 0.8 -1.4
Suffer from ‘nerves’ 0.5 0.8 1.8 -1.1 1.4 -1.1 -1.0 -1.1 -0.9 -0.5 -1.1 1.1 -0.5 -0.7 -1.0 0.2 -0.2
Overall health rating 0.8 1.7 3.1 1.4 -1.4 1.6 1.5 1.4 1.1 0.1 1.4 1.0 1.1 1.6 1.4 -0.0 1.8
Chest pain or discomfort 0.9 1.2 3.5 -1.1 0.7 -1.2 -1.2 -1.4 -0.7 0.6 -1.4 -0.1 -0.7 -1.1 -1.2 1.9 -1.1
Had major operations 1.4 1.7 8.2 -0.8 0.5 -0.8 -1.5 -0.9 -0.1 -2.0 -1.0 0.0 -2.9 0.3 -1.4 -1.5 -1.0
Age at last live birth 0.5 0.7 1.7 -1.0 0.8 -0.5 -0.8 -0.9 -0.4 0.1 -0.9 1.3 0.7 -1.2 -0.6 -0.8 0.7
Family relationship satisfaction 0.2 0.2 1.2 -0.1 0.9 -0.3 0.1 -0.1 0.3 0.3 -0.1 -1.1 0.4 0.6 -0.1 0.3 -0.1
Leg pain on walking 2.1 2.6 7.0 1.8 -1.6 1.4 1.6 1.7 2.0 -2.6 1.6 0.7 -0.6 2.3 1.2 1.3 0.8
Qualifications: NVQ or HND or HNC or equivalent 0.9 1.0 7.7 0.6 -1.5 0.3 -0.1 0.8 -0.5 0.2 0.7 0.9 0.9 0.4 0.4 -2.8 -0.8
Commuting to job workplace: Car/motor vehicle 0.5 0.6 2.7 -0.4 -1.1 -0.8 -0.1 -0.3 -1.6 -1.0 -0.3 -0.4 0.3 -0.0 -0.8 -0.9 -0.6
Illness, injury, bereavement, stress in last 2 years 0.6 0.8 5.8 -0.7 -0.3 -0.8 -0.6 -0.6 0.8 -2.4 -0.6 -0.6 0.2 -0.5 -0.6 0.9 0.2
Medication: Aspirin 1.3 1.7 4.6 -2.2 -1.9 -1.7 -1.0 -1.6 -1.0 0.3 -1.6 0.6 -0.6 -0.5 -1.6 1.2 0.6
Supplements: Vitamin C 0.5 0.6 1.3 -1.0 -0.2 -1.1 -0.9 -0.9 0.9 -0.3 -0.9 -0.6 -0.4 -0.1 -1.1 0.4 -0.8
Knee pain experienced in last month 0.3 0.5 1.7 0.5 0.6 0.8 0.3 0.6 0.3 -1.0 0.5 0.7 -0.7 0.8 0.5 -1.3 -0.2
Hypertension (Self-reported) 0.3 0.9 3.1 0.1 -1.8 0.2 0.4 0.2 0.2 0.0 0.1 1.4 -1.3 1.7 0.1 -1.2 1.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.5 0.6 1.8 0.3 0.9 0.0 -0.1 0.1 -0.7 -0.4 0.2 -1.2 1.1 -0.9 0.1 1.4 -1.2
Illnesses of father: Heart disease 1.9 2.6 6.1 -2.3 -0.8 -2.1 -1.9 -2.0 0.1 0.4 -2.0 0.3 -1.5 -0.7 -2.2 -0.7 -2.5
Illnesses of siblings: Diabetes 0.7 0.9 2.2 -1.0 0.4 -0.9 -1.3 -1.5 0.4 0.1 -1.4 0.5 -0.6 -0.9 -1.1 -0.4 -1.4
Smoking status: Previous 0.4 0.6 3.2 0.5 -0.1 0.6 0.5 0.5 -0.0 0.4 0.5 -0.4 1.5 -0.4 0.8 -1.8 -0.4
Forced expiratory volume in 1-second (FEV1), predicted 1.0 2.0 5.0 -1.2 0.2 -2.1 -1.1 -1.4 -2.1 0.1 -1.5 -0.7 -0.5 -1.5 -2.0 0.3 -2.2
Whole body fat-free mass 0.1 0.7 5.6 -0.3 0.4 -0.5 -0.3 -0.6 -0.8 0.2 -0.6 -2.4 -0.3 -1.0 -0.4 0.6 -0.0
Leg fat-free mass (right) 0.1 0.5 2.3 -0.2 -0.1 -0.6 -0.2 -0.4 -0.9 0.9 -0.5 -1.5 -0.4 -0.9 -0.5 0.6 0.3
Arm fat percentage (left) 0.3 1.2 5.6 1.2 -2.4 0.7 1.2 1.2 0.4 0.4 1.3 0.7 0.2 0.9 0.8 -0.6 1.2
Average weekly red wine intake 1.3 1.9 4.0 -1.8 -0.8 -1.9 -1.6 -1.8 -0.9 1.0 -1.8 0.1 -1.3 -1.0 -2.0 0.7 -1.3
Handedness (chirality/laterality): Left-handed 0.4 0.4 3.1 0.1 -0.0 -0.3 0.1 -0.2 0.1 0.6 -0.2 -1.4 -0.2 0.2 -0.3 1.8 -0.4
Mood swings 1.2 2.1 6.7 1.2 -2.6 1.4 1.4 1.1 1.7 0.4 1.0 1.3 -0.3 2.0 1.3 0.5 2.2
Loneliness, isolation 1.2 1.6 8.3 0.8 0.2 0.6 0.9 0.8 1.4 -0.4 0.6 2.9 -1.6 1.8 0.5 -1.7 0.8
Long-standing illness, disability or infirmity 0.8 1.2 7.0 0.6 -2.6 0.5 0.3 0.4 1.0 -1.5 0.2 0.6 -1.0 1.9 0.2 1.1 -0.3
Ever had bowel cancer screening 0.8 1.0 4.6 -0.5 -1.1 0.3 0.3 -0.1 -0.5 -1.1 -0.2 2.1 -0.1 0.8 0.2 -2.1 0.9
Diabetes diagnosed by doctor 0.6 0.9 3.3 0.3 -1.2 0.6 0.8 0.4 1.2 1.8 0.3 0.3 1.1 1.2 0.9 0.2 1.4
Ever had stillbirth, spontaneous miscarriage or termination 0.8 0.8 1.9 1.0 1.4 0.9 1.1 1.2 -0.3 0.9 1.1 -0.5 0.1 1.0 1.0 -0.8 0.6
Friendships satisfaction 0.4 0.5 1.9 -0.3 1.4 -0.1 0.1 -0.2 -1.4 1.4 -0.2 -0.7 0.1 0.3 0.1 0.4 0.4
Qualifications: nursing, teaching 0.9 1.4 2.9 -1.5 1.2 -1.3 -1.6 -1.5 1.0 0.6 -1.5 0.0 0.2 -1.7 -1.3 0.7 -0.8
Commuting to job workplace: Walk 1.1 1.1 4.6 -0.3 2.1 -0.4 -0.6 -0.4 -0.4 0.6 -0.4 -2.1 0.7 -1.7 -0.0 0.6 -1.5
Eye problems/disorders: Cataract 2.6 3.0 8.8 -0.9 -1.0 -1.8 -1.3 -1.4 -2.1 -1.8 -1.6 0.6 -3.0 0.3 -2.2 -1.7 -2.4
Mouth/teeth dental problems: Mouth ulcers 0.6 0.9 5.1 0.1 2.3 0.8 0.5 0.6 1.2 0.6 0.5 -1.4 0.8 -0.1 0.7 0.6 1.1
Medication for cholesterol 1.3 2.0 7.2 -1.4 1.7 -1.4 -1.7 -1.5 -0.4 -0.8 -1.4 -0.1 0.8 -2.7 -1.1 0.8 -1.9
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.8 0.9 4.5 -0.9 -1.7 -0.8 -0.5 -0.9 -2.1 -0.7 -0.9 -0.2 -0.5 -0.1 -1.0 -0.0 0.7
Back pain experienced in last month 0.4 0.6 1.9 1.1 -1.0 0.6 1.0 0.9 0.0 -0.5 0.8 -0.7 0.5 0.9 0.5 -0.3 1.4
Mineral and other dietary supplements 0.6 0.8 2.6 -0.6 -0.6 -0.4 -1.1 -1.0 -1.6 -0.6 -0.9 -1.6 -0.5 -1.2 -0.4 -0.3 -0.7
Breast cancer (self-reported) 1.5 1.8 3.5 -1.8 -0.6 -1.8 -1.8 -1.9 -0.8 -0.8 -1.8 -0.2 -1.2 -1.2 -1.7 0.1 -1.1
Asthma (self-reported) 0.9 1.8 3.2 -1.4 -0.8 -1.7 -1.6 -1.6 -0.7 -0.7 -1.6 -0.9 -0.8 -1.5 -1.8 -0.6 -1.8
Osteoporosis (self-reported) 0.3 0.3 2.4 -0.1 0.8 -0.2 -0.0 -0.1 0.4 -0.5 -0.1 0.6 -0.2 -0.3 -0.4 1.6 -0.5
Osteoarthritis (self-reported) 0.5 0.6 1.8 1.0 0.2 0.4 1.1 0.7 -0.6 -0.8 0.6 0.2 -0.7 0.7 0.6 1.2 1.3
Medication: Aspirin 1.1 1.4 4.3 -1.9 -2.1 -1.4 -0.9 -1.3 -0.6 -0.2 -1.4 0.1 -0.9 -0.1 -1.4 1.3 0.6
Medication: Gliclazide 0.2 0.2 0.9 -0.3 0.6 -0.5 -0.3 -0.3 -0.8 -0.8 -0.4 -1.0 -0.1 0.2 -0.3 -0.2 -0.2
Illnesses of father: None of the above (group 1) 0.5 0.6 4.1 -0.5 -0.1 -0.7 -0.5 -0.5 0.0 -0.3 -0.5 -1.3 0.2 -0.8 -0.4 2.0 0.3
Smoking status: Current 0.3 0.5 1.7 0.3 -0.4 0.1 0.5 0.3 -0.9 -0.1 0.3 0.4 -0.9 1.3 0.0 -1.2 0.9
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.2 0.5 2.8 0.6 0.6 0.8 0.8 0.7 -0.3 0.4 0.8 -0.2 0.7 0.2 0.6 -0.3 1.7
Whole body water mass 0.1 0.5 5.3 -0.2 0.2 -0.3 -0.2 -0.4 -0.6 0.2 -0.5 -2.3 -0.2 -0.8 -0.3 0.7 0.1
Leg predicted mass (right) 0.1 0.4 2.3 -0.2 -0.2 -0.6 -0.2 -0.4 -0.9 0.7 -0.5 -1.5 -0.4 -0.9 -0.5 0.6 0.4
Arm fat mass (left) 0.2 1.0 3.8 1.3 -2.0 0.9 1.1 1.2 0.3 0.2 1.3 -0.0 0.4 0.6 1.0 -0.6 1.0
Number of self-reported non-cancer illnesses 0.5 0.9 4.1 -0.2 -1.5 -0.4 -0.1 -0.3 1.3 -0.4 -0.4 1.4 -1.1 0.4 -0.3 -2.0 -0.2
Average weekly champagne plus white wine intake 0.7 1.0 2.1 -1.4 -0.6 -0.8 -1.0 -1.1 1.0 1.2 -1.1 -0.4 0.8 -0.4 -1.0 1.2 1.1
Miserableness 0.3 0.5 1.9 -0.0 -1.2 -0.1 -0.0 -0.2 0.1 1.1 -0.2 0.5 0.9 0.0 -0.0 1.4 0.8
Guilty feelings 0.4 0.6 4.4 -0.1 0.1 -0.3 -0.0 -0.3 1.2 1.1 -0.3 2.1 -0.2 -0.2 -0.1 -0.8 -0.6
Wears glasses or contact lenses 0.7 0.8 3.4 -0.8 1.4 -0.9 -0.3 -0.4 0.7 -1.0 -0.5 -1.9 -0.3 -0.6 -0.8 1.1 0.1
Ever taken oral contraceptive pill 0.8 0.9 3.0 -0.9 0.9 -0.9 -1.0 -0.8 -0.7 -0.7 -0.9 -0.4 -1.2 0.0 -1.3 0.9 -1.7
Hearing aid user 1.1 1.3 2.4 -1.4 -1.4 -1.0 -1.3 -1.3 0.1 -1.4 -1.3 1.3 -1.5 -0.6 -1.2 0.4 -0.6
Mother’s age at death 1.0 1.2 2.6 1.1 -0.1 1.0 0.9 1.2 0.6 -1.6 1.1 -1.3 -0.8 1.6 1.1 -0.8 1.5
Financial situation satisfaction 0.1 0.1 0.8 0.1 0.0 0.2 -0.4 -0.2 -0.6 -0.0 -0.1 -0.4 -0.2 0.4 -0.0 0.9 -0.2
Tinnitus: Yes, now most or all of the time 0.5 0.6 1.7 -0.8 -0.5 -0.8 -1.0 -1.0 -0.1 0.7 -0.9 -0.5 -0.0 -1.3 -0.6 -0.3 -1.0
Commuting to job workplace: Public transport 0.4 0.5 3.0 -0.4 -0.2 -0.2 -0.5 -0.4 0.8 -1.7 -0.4 0.2 -0.2 -0.6 -0.2 1.3 -0.0
Eye problems/disorders: Glaucoma 0.8 1.0 3.0 -0.9 0.8 -1.0 -0.8 -1.0 -0.2 -0.2 -0.9 -1.2 -0.1 -1.7 -1.0 1.6 -0.4
Medication: Blood pressure 0.8 1.5 6.6 0.7 -1.9 0.9 1.2 1.0 0.3 0.8 0.9 0.3 -1.1 2.6 0.7 -1.4 1.4
Pain type(s) experienced in last month: Hip pain 0.7 0.8 2.1 0.7 -1.5 0.5 1.0 0.9 -0.4 0.9 0.8 -0.2 -0.1 1.3 0.6 -0.9 1.4
Supplements: Fish oil (including cod liver oil) 0.9 1.2 4.2 0.8 -0.5 0.6 1.2 1.1 1.6 0.2 1.0 2.0 -0.1 1.6 0.5 -0.3 1.3
High cholesterol (Self-reported) 1.9 3.4 6.2 2.1 -0.0 2.1 2.3 2.0 1.8 1.1 2.0 2.5 0.5 2.0 2.1 -1.3 2.0
Medication: Bendroflumethiazide 0.6 0.9 4.5 -1.1 -0.5 -0.6 -0.7 -0.7 -1.4 0.4 -0.8 -2.1 -0.5 0.3 -0.7 -1.2 1.1
Medication: Paracetamol 0.2 0.3 1.2 -0.0 -0.2 0.1 0.0 0.1 -1.1 -0.6 -0.0 -0.7 -0.5 0.5 -0.1 0.7 0.7
Medication: Lisinopril 1.2 1.5 6.0 -1.2 -1.4 -1.0 -1.0 -1.1 2.5 0.8 -1.2 0.8 -0.3 -1.1 -1.1 -1.7 -0.8
Medication: Atorvastatin 3.3 4.1 11.1 1.8 -1.9 2.4 1.9 2.2 2.0 -0.3 2.1 0.8 -0.6 3.3 2.1 -0.7 3.3
Illnesses of father: High blood pressure 0.3 0.3 1.5 0.0 0.7 -0.3 -0.4 -0.4 -0.5 -0.5 -0.5 -1.2 -0.6 -0.3 -0.5 -0.4 -0.9
Alcohol drinker status: Never 0.4 0.5 3.5 0.4 -0.8 0.4 0.3 0.1 0.1 -0.5 0.1 0.3 -0.6 0.6 0.2 1.9 1.0
Ever smoked 0.6 1.1 9.3 0.5 0.3 0.4 0.6 0.7 0.1 0.4 0.7 -0.5 1.6 -0.5 0.8 -3.1 0.4
Basal metabolic rate 0.1 0.4 4.0 -0.0 -0.1 -0.2 -0.0 -0.2 -0.5 0.3 -0.3 -2.0 -0.3 -0.6 -0.2 0.5 0.3
Leg fat percentage (left) 1.3 4.5 7.7 2.7 -2.6 2.2 2.5 2.7 1.1 0.9 2.7 0.6 0.6 2.8 2.2 -1.1 2.7
Arm fat-free mass (left) 0.1 0.4 4.1 0.5 -0.4 0.3 0.4 0.3 -0.3 -0.2 0.2 -2.0 -0.2 -0.0 0.3 0.3 0.5
Number of operations (self-reported) 2.0 3.0 11.5 -1.6 0.1 -1.7 -2.0 -1.8 0.9 -1.5 -2.0 -0.6 -3.4 -0.3 -2.0 -1.7 -2.0
Average weekly beer plus cider intake 0.3 0.5 2.1 -0.4 -0.5 -0.1 -0.5 -0.3 -1.4 -1.3 -0.3 -0.2 -1.1 0.7 -0.3 -0.9 0.1
Irritability 0.4 0.6 3.6 0.6 -0.9 0.9 0.3 0.4 0.3 0.3 0.3 0.1 -0.5 1.3 0.4 0.6 1.9
Risk taking 0.3 0.5 2.3 0.1 -1.5 -0.2 -0.2 -0.0 -1.0 0.2 -0.1 -0.4 -0.6 0.8 -0.2 -1.4 0.1
Ever had prostate specific antigen (PSA) test 0.5 0.5 2.2 -0.6 -0.1 -0.8 -0.9 -0.7 0.0 -1.5 -0.7 -0.5 -0.7 -0.9 -0.9 -0.2 -0.3
Fractured/broken bones in last 5 years 0.7 1.0 4.2 -0.6 0.1 -1.1 -0.5 -0.9 -1.2 0.5 -1.0 1.0 -2.0 -0.0 -1.4 -0.9 0.2
Age started oral contraceptive pill 2.1 2.7 5.1 1.9 0.3 2.0 2.0 1.8 1.6 0.4 1.9 1.0 1.4 1.7 2.3 1.2 1.8
Diastolic blood pressure, automated reading 1.1 3.6 8.6 -2.3 0.6 -1.9 -2.5 -2.4 -0.6 -0.1 -2.4 -0.5 -0.8 -2.9 -1.7 -1.4 -2.8
Ever depressed for a whole week 0.7 0.9 3.7 -0.8 -1.9 -0.7 -0.9 -0.6 -0.4 -1.2 -0.7 -0.1 -1.2 -0.2 -0.6 -0.9 -1.3
Unable to work because of sickness or disability 1.0 1.4 8.6 1.1 -2.9 0.6 1.3 1.2 0.4 0.0 1.1 0.6 0.6 1.3 0.6 1.0 0.6
Commuting to job workplace: Cycle 0.7 0.9 2.0 0.9 0.4 1.4 0.7 1.0 0.6 0.9 1.1 1.1 0.9 0.7 1.2 0.5 1.0
Myopia 0.7 1.0 2.0 -1.1 1.3 -0.5 -1.4 -1.2 -0.8 -0.6 -1.3 0.2 -1.4 -0.8 -0.8 0.6 -0.9
Vascular/heart problems diagnosed by doctor 0.3 0.9 2.8 -0.0 1.6 -0.5 -0.5 -0.3 -0.3 -0.0 -0.2 -1.7 1.2 -1.6 -0.4 1.3 -1.1
Cholesterol lowering medication 0.8 1.1 3.0 1.0 -1.4 0.9 1.2 0.9 1.1 0.9 0.9 1.1 -0.6 1.4 0.8 0.3 1.7
Medication: Omeprazole (e.g. Zanprol) 1.0 1.2 3.1 -1.1 -0.8 -1.1 -0.9 -1.2 -0.1 0.0 -1.2 0.0 -0.5 -1.8 -1.2 1.4 -1.6
Pain experienced in last month 0.4 0.7 4.1 0.2 2.0 0.8 0.1 0.4 0.1 0.2 0.5 -1.4 0.8 -0.5 0.8 1.0 0.1
Supplements: Calcium 0.7 0.8 6.9 0.0 1.5 -0.3 0.3 0.1 1.0 0.8 0.2 -0.2 0.0 0.3 -0.3 2.6 0.6
Basal cell carcinoma (self-reported) 0.6 0.7 4.3 0.8 0.1 1.1 0.5 0.5 -0.9 -0.3 0.7 -0.2 0.8 0.2 0.9 -2.1 0.2
Heart attack/myocardial infarction (self-reported) 1.3 1.7 4.7 1.5 0.1 1.4 1.8 1.8 0.6 0.1 1.8 0.7 0.8 1.2 1.5 0.7 2.2
Deep venous thrombosis (DVT) (self-reported) 0.6 0.8 3.8 0.4 -0.5 0.4 0.4 0.4 0.2 1.6 0.5 0.1 2.0 -0.9 0.6 -1.3 0.4
Heart disease (siblings) 0.5 0.7 1.5 0.8 0.6 1.1 0.8 1.0 -1.0 -0.1 1.0 -1.2 0.4 -0.1 1.2 -0.3 -0.4
Alcohol drinker status: Previous 0.5 0.6 2.2 -0.2 1.5 -0.6 -0.5 -0.3 -0.6 0.4 -0.2 0.9 -1.2 -1.0 -0.4 0.1 -1.2
Pack years of smoking 2.3 3.4 6.5 2.5 0.9 2.2 2.4 2.3 0.5 0.7 2.4 2.0 -0.2 2.1 2.3 -1.3 1.4
Impedance of whole body 0.1 0.5 1.8 -0.8 -0.1 -0.8 -0.3 -0.6 0.2 -0.4 -0.6 1.4 -0.8 0.8 -1.0 -0.0 -0.1
Leg fat mass (left) 0.5 2.1 4.5 2.0 -1.8 1.4 1.7 1.8 0.5 0.4 1.8 -0.0 0.1 1.6 1.5 -0.8 2.1
Arm predicted mass (left) 0.1 0.4 4.4 0.4 -0.4 0.1 0.3 0.0 -0.5 0.0 -0.0 -2.1 -0.5 -0.2 0.1 0.4 0.5