Best TWAS P=5.14e-08 · Best GWAS P=1.79e-08 conditioned to 0.106
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | The Cancer Genome Atlas | Brain Lower Grade Glioma | PMS2CL | 0.10 | 0.12 | blup | 22 | 0.12 | 4.6e-14 | 5.6 | -5.5 | 5.1e-08 | -0.91 | 0 | 1.00 | TRUE |
2 | The Cancer Genome Atlas | Testicular Germ Cell Tumors | PMS2CL | 0.14 | 0.10 | lasso | 2 | 0.07 | 1.5e-03 | 5.3 | -5.3 | 1.2e-07 | -0.90 | 0 | 0.86 | FALSE |
3 | The Cancer Genome Atlas | Thyroid Carcinoma | PMS2CL | 0.08 | 0.12 | lasso | 5 | 0.11 | 1.0e-10 | 5.3 | -5.3 | 9.2e-08 | -0.90 | 0 | 0.99 | FALSE |