Best TWAS P=4.66e-08 · Best GWAS P=2.55e-09 conditioned to 0.0159
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | KBTBD2 | 0.11 | 0.04 | enet | 22 | 0.02 | 1.6e-02 | -5.4 | -5.4 | 7.4e-08 | -0.71 | 0.01 | 0.93 | FALSE |
| 2 | GTEx | Skin Sun Exposed Lower leg | KBTBD2 | 0.17 | 0.08 | lasso | 2 | 0.06 | 1.2e-05 | -5.2 | -5.2 | 2.0e-07 | -0.67 | 0.09 | 0.90 | FALSE |
| 3 | The Cancer Genome Atlas | Breast Invasive Carcinoma | KBTBD2 | 0.02 | 0.01 | enet | 4 | 0.01 | 5.4e-03 | 6.0 | -5.5 | 4.7e-08 | -0.94 | 0.00 | 0.98 | TRUE |