Best TWAS P=1.88e-08 · Best GWAS P=1.88e-09 conditioned to 5.68e-09
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Adipose Subcutaneous | DDX6 | 0.07 | 0.04 | lasso | 1 | 0.01 | 3.2e-02 | -5.6 | -5.6 | 1.9e-08 | 0.13 | 0.01 | 0.94 | TRUE |
2 | GTEx | Nerve Tibial | HINFP | 0.15 | 0.17 | lasso | 3 | 0.16 | 2.9e-11 | -4.6 | -5.1 | 2.8e-07 | -0.09 | 0.53 | 0.46 | FALSE |
3 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | HINFP | 0.10 | 0.05 | blup | 46 | 0.05 | 3.0e-03 | 4.3 | -5.3 | 1.0e-07 | -0.09 | 0.01 | 0.46 | TRUE |