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chr11:110,469,326-112,335,631

Best TWAS P=1.86e-09 · Best GWAS P=3.64e-14 conditioned to 0.00344

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex PPP2R1B 0.14 0.18 enet 19 0.19 8.3e-23 4.7 5.1 3.0e-07 0.12 1.00 0.00 FALSE
2 GTEx Adipose Subcutaneous PPP2R1B 0.11 0.05 enet 16 0.08 4.4e-07 2.8 6.0 1.9e-09 0.32 0.96 0.00 TRUE
3 GTEx Adipose Visceral Omentum PPP2R1B 0.07 0.00 lasso 9 0.00 2.2e-01 4.6 5.6 1.6e-08 0.21 0.32 0.23 FALSE
4 GTEx Artery Aorta COLCA2 0.09 0.10 lasso 2 0.07 1.3e-04 -5.6 -5.5 3.2e-08 -0.55 0.18 0.32 FALSE
5 GTEx Brain Cortex PPP2R1B 0.16 0.07 lasso 2 0.09 1.8e-03 4.6 5.2 2.2e-07 0.09 0.15 0.14 FALSE
6 GTEx Lung PPP2R1B 0.12 0.10 lasso 4 0.10 5.6e-08 4.6 5.4 7.9e-08 0.19 0.97 0.00 FALSE
7 GTEx Nerve Tibial COLCA1 0.18 0.04 lasso 4 0.03 2.3e-03 5.7 5.4 8.0e-08 0.82 0.18 0.73 FALSE
8 GTEx Ovary PPP2R1B 0.40 -0.01 enet 36 0.10 1.5e-03 2.1 6.0 2.6e-09 0.27 0.07 0.19 FALSE
9 The Cancer Genome Atlas Prostate Adenocarcinoma C11orf92 0.03 0.02 blup 54 0.02 2.5e-03 3.7 -5.3 1.5e-07 -0.75 0.22 0.41 TRUE
10 The Cancer Genome Atlas Prostate Adenocarcinoma C11orf93 0.04 0.00 blup 58 0.02 1.7e-03 3.7 -5.9 2.9e-09 -0.75 0.06 0.29 FALSE