Best TWAS P=1.93e-08 · Best GWAS P=1.73e-09 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Muscle Skeletal | FBXO21 | 0.17 | 0.13 | lasso | 10 | 0.14 | 1.0e-13 | -5.9 | 5.6 | 1.9e-08 | -0.95 | 0.01 | 0.99 | TRUE |
| 2 | GTEx | Nerve Tibial | FBXO21 | 0.26 | 0.17 | lasso | 4 | 0.16 | 1.7e-11 | -5.5 | 5.3 | 9.1e-08 | -0.57 | 0.12 | 0.88 | FALSE |
| 3 | The Cancer Genome Atlas | Prostate Adenocarcinoma | FBXO21 | 0.03 | 0.03 | blup | 55 | 0.02 | 2.0e-03 | -4.9 | 5.4 | 5.4e-08 | -0.82 | 0.03 | 0.76 | FALSE |