Best TWAS P=1.87e-23 · Best GWAS P=6.26e-27 conditioned to 1.02e-06
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells EBV-transformed lymphocytes | FBRSL1 | 0.35 | 0.07 | lasso | 7 | 0.09 | 6.1e-04 | 8.7 | -10.0 | 1.9e-23 | -0.61 | 0.01 | 0.86 | TRUE |
| 2 | GTEx | Nerve Tibial | RP13-977J11.5 | 0.22 | 0.00 | enet | 26 | 0.03 | 1.7e-03 | 3.1 | 5.3 | 1.3e-07 | 0.16 | 0.05 | 0.10 | TRUE |
| 3 | GTEx | Pancreas | FBRSL1 | 0.49 | 0.38 | lasso | 5 | 0.36 | 3.2e-16 | 8.7 | 9.8 | 8.1e-23 | 0.82 | 0.08 | 0.92 | FALSE |
| 4 | METSIM | Adipose | FBRSL1 | 0.09 | 0.01 | blup | 286 | 0.03 | 1.7e-05 | -7.8 | -7.6 | 2.2e-14 | -0.15 | 0.56 | 0.02 | FALSE |