Best TWAS P=9.62e-08 · Best GWAS P=6.45e-09 conditioned to 0.00656
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Skin Sun Exposed Lower leg | THUMPD1 | 0.06 | 0.01 | enet | 18 | 0.00 | 4.5e-01 | -5.7 | 5.2 | 2.7e-07 | -0.57 | 0.04 | 0.78 | FALSE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | ACSM1 | 0.07 | 0.06 | lasso | 8 | 0.06 | 1.0e-07 | -5.2 | -5.2 | 2.0e-07 | 0.75 | 0.07 | 0.93 | FALSE |
| 3 | The Cancer Genome Atlas | Brain Lower Grade Glioma | ACSM1 | 0.11 | 0.06 | lasso | 4 | 0.05 | 1.9e-06 | -5.1 | -5.3 | 9.6e-08 | 0.75 | 0.09 | 0.91 | TRUE |