[Hub]/) : Traits : Blood Red Count :

chr19:53,922,287-55,427,510

Best TWAS P=7.19e-10 · Best GWAS P=2.84e-09 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous TMC4 0.19 0.19 lasso 4 0.17 1.4e-13 -5.3 5.4 5.2e-08 0.03 0.07 0.93 FALSE
2 GTEx Artery Aorta TMC4 0.23 0.05 lasso 5 0.06 2.0e-04 -5.3 5.2 1.8e-07 0.04 0.13 0.72 FALSE
3 GTEx Artery Tibial TMC4 0.17 0.07 lasso 6 0.13 3.9e-10 3.5 5.4 7.1e-08 0.06 0.35 0.65 FALSE
4 GTEx Brain Caudate basal ganglia CTD-3093M3.1 0.57 -0.01 lasso 13 0.01 1.3e-01 2.8 5.1 2.7e-07 0.16 0.05 0.13 FALSE
5 GTEx Brain Cortex TMC4 0.28 0.26 lasso 4 0.24 2.8e-07 -5.3 5.5 3.3e-08 0.04 0.09 0.75 FALSE
6 GTEx Brain Frontal Cortex BA9 TMC4 0.44 0.10 enet 20 0.09 1.9e-03 -5.3 5.6 1.8e-08 0.12 0.12 0.54 FALSE
7 GTEx Breast Mammary Tissue TMC4 0.23 0.17 lasso 5 0.17 3.8e-09 -5.3 5.2 1.5e-07 0.03 0.09 0.90 FALSE
8 GTEx Esophagus Mucosa TMC4 0.47 0.50 lasso 2 0.50 1.9e-38 -5.3 5.3 1.4e-07 0.04 0.07 0.93 FALSE
9 GTEx Esophagus Muscularis TMC4 0.23 0.17 lasso 3 0.16 9.9e-10 -5.3 5.3 1.1e-07 0.02 0.08 0.92 FALSE
10 GTEx Heart Atrial Appendage TMC4 0.33 0.18 lasso 4 0.28 9.2e-13 3.5 5.2 2.4e-07 0.01 0.29 0.71 FALSE
11 GTEx Heart Left Ventricle TMC4 0.38 0.24 lasso 6 0.25 1.6e-13 -5.3 5.3 9.2e-08 0.02 0.08 0.92 FALSE
12 GTEx Muscle Skeletal TMC4 0.25 0.26 enet 21 0.26 1.1e-25 -5.3 5.8 7.3e-09 0.03 0.07 0.93 TRUE
13 GTEx Nerve Tibial PRPF31 0.17 0.08 lasso 6 0.10 9.2e-08 -4.7 5.3 9.9e-08 0.03 0.51 0.44 FALSE
14 GTEx Skin Not Sun Exposed Suprapubic TMC4 0.45 0.28 lasso 6 0.26 3.0e-14 -5.3 5.3 1.2e-07 0.04 0.07 0.93 FALSE
15 GTEx Spleen TMC4 0.46 0.14 enet 17 0.26 3.0e-07 -5.2 5.5 3.8e-08 0.03 0.15 0.53 FALSE
16 GTEx Whole Blood TMC4 0.27 0.25 lasso 7 0.28 1.6e-25 -5.3 5.8 8.7e-09 0.02 0.07 0.93 FALSE
17 NTR Blood LILRA3 0.30 0.34 enet 10 0.35 1.0e-116 5.9 -6.2 7.2e-10 -0.97 0.00 1.00 TRUE
18 YFS Blood LILRA3 0.67 0.60 bslmm 410 0.72 0.0e+00 5.9 -5.7 1.4e-08 -0.89 0.00 1.00 FALSE
19 YFS Blood MBOAT7 0.08 0.02 enet 26 0.05 5.5e-16 -2.3 5.5 3.1e-08 0.09 0.49 0.50 FALSE
20 YFS Blood TMC4 0.13 0.14 bslmm 409 0.16 6.0e-49 -5.3 5.4 7.8e-08 0.00 0.08 0.92 FALSE
21 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma TMC4 0.03 0.03 blup 7 0.03 1.2e-04 -4.0 5.2 1.7e-07 0.03 0.00 0.84 FALSE
22 The Cancer Genome Atlas Soft Tissue Sarcoma TMC4 0.11 0.08 lasso 1 0.08 2.4e-05 -5.2 5.2 2.2e-07 -0.01 0.00 0.98 FALSE
23 The Cancer Genome Atlas Thyroid Carcinoma PRPF31 0.07 0.01 enet 6 0.03 1.0e-03 -5.2 5.3 1.1e-07 0.05 0.00 0.96 FALSE