Best TWAS P=1.65e-07 · Best GWAS P=1.86e-12 conditioned to 2.41e-06
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Colon Transverse | LY75 | 0.16 | 0.13 | lasso | 4 | 0.16 | 8.1e-08 | -5.5 | -5.2 | 1.7e-07 | -0.73 | 0.52 | 0.48 | TRUE |
| 2 | GTEx | Uterus | LY75 | 0.24 | 0.23 | lasso | 5 | 0.23 | 1.5e-05 | 4.4 | -5.2 | 1.8e-07 | -0.63 | 0.27 | 0.09 | FALSE |
| 3 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | LY75 | 0.05 | 0.08 | lasso | 3 | 0.07 | 1.0e-08 | 5.2 | -5.2 | 2.1e-07 | -0.69 | 0.97 | 0.02 | FALSE |