Best TWAS P=3.93e-11 · Best GWAS P=1.61e-16 conditioned to 3.43e-08
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Muscularis | GRB14 | 0.14 | 0.09 | lasso | 7 | 0.06 | 0.00016 | -5.3 | 5.2 | 2.3e-07 | -0.47 | 0.27 | 0.45 | FALSE |
| 2 | The Cancer Genome Atlas | Colon Adenocarcinoma | GRB14 | 0.09 | 0.01 | blup | 82 | 0.03 | 0.00464 | -6.7 | 6.6 | 3.9e-11 | -0.55 | 0.02 | 0.64 | TRUE |