TWAS
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Usage
Models
Genes
Traits
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Traits
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Blood Red Count
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chr5:61,013,371-62,621,119
Best TWAS P=8.09e-09 · Best GWAS P=8.94e-08 conditioned to 0.0236
61M
61.2M
61.4M
61.6M
61.8M
62M
62.2M
62.4M
62.6M
0
2
4
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
CommonMind
Brain Pre-frontal Cortex
IPO11
0.07
0.03
lasso
6
0.08
1.3e-09
-3.6
-5.8
8.1e-09
-0.62
0.10
0.89
TRUE
2
The Cancer Genome Atlas
Prostate Adenocarcinoma
IPO11
0.03
0.00
blup
127
0.01
3.0e-02
-4.1
-5.5
2.9e-08
-0.56
0.03
0.34
FALSE