Hub : Genes

IPO11

Models

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0670	0.0320	6.8e-06	0.033	0.041	0.074	0.049	0.077	6.0e-05	9.2e-06	2.5e-09	1.1e-06	1.3e-09
2	GTEx	Breast Mammary Tissue	0.1860	0.0680	1.4e-03	-0.005	NA	0.002	NA	-0.004	7.1e-01	NA	2.4e-01	NA	6.2e-01
3	GTEx	Breast Mammary Tissue (Male)	0.0101	0.0517	4.4e-01	-0.001	NA	-0.009	NA	0.017	3.4e-01	NA	6.1e-01	NA	1.3e-01
4	GTEx	Nerve Tibial	0.1416	0.0588	2.6e-03	-0.001	NA	-0.001	NA	-0.003	3.8e-01	NA	3.6e-01	NA	5.5e-01
5	GTEx	Testis	0.1660	0.0880	2.2e-03	0.022	NA	0.043	NA	0.019	3.7e-02	NA	5.6e-03	NA	4.8e-02
6	METSIM	Adipose	0.0644	0.0269	1.5e-03	0.003	0.023	0.008	0.026	0.008	1.1e-01	1.7e-04	1.9e-02	7.6e-05	1.8e-02
7	YFS	Blood	0.0299	0.0119	2.8e-04	0.000	0.018	0.014	0.018	0.004	2.2e-01	1.0e-06	1.1e-05	1.2e-06	1.3e-02
8	TCGA	Bladder Urothelial Carcinoma	0.0750	0.0490	2.0e-03	0.018	0.006	0.000	NA	0.006	1.1e-02	9.6e-02	2.9e-01	NA	9.3e-02
9	TCGA	Breast Invasive Carcinoma	0.0950	0.0375	2.6e-13	0.059	0.066	0.064	NA	0.062	3.4e-12	1.7e-13	4.3e-13	NA	1.2e-12
10	TCGA	Esophageal Carcinoma	0.1350	0.0720	7.0e-03	0.009	0.012	0.003	NA	0.015	1.7e-01	1.3e-01	2.4e-01	NA	1.1e-01
11	TCGA	Head and Neck Squamous Cell Carcinoma	0.0732	0.0431	6.8e-06	0.021	0.047	0.050	NA	0.043	1.7e-03	5.3e-06	2.3e-06	NA	1.1e-05
12	TCGA	Brain Lower Grade Glioma	0.0405	0.0233	2.1e-03	0.031	0.014	0.019	NA	0.017	1.6e-04	9.2e-03	2.6e-03	NA	4.3e-03
13	TCGA	Lung Adenocarcinoma	0.0635	0.0474	2.4e-03	0.026	0.022	0.025	NA	0.026	4.6e-04	1.3e-03	5.1e-04	NA	4.2e-04
14	TCGA	Lung Squamous Cell Carcinoma	0.0804	0.0389	7.2e-06	0.043	0.047	0.040	NA	0.041	1.1e-05	4.2e-06	1.9e-05	NA	1.6e-05
15	TCGA	Prostate Adenocarcinoma	0.0329	0.0212	8.6e-03	-0.001	0.010	-0.002	NA	-0.001	4.2e-01	3.0e-02	5.5e-01	NA	4.6e-01
16	TCGA	Soft Tissue Sarcoma	0.0800	0.0490	5.3e-03	0.007	-0.001	-0.003	NA	0.044	1.2e-01	3.7e-01	5.8e-01	NA	1.3e-03
17	TCGA	Stomach Adenocarcinoma	0.1390	0.0970	5.3e-04	0.053	0.026	0.019	NA	0.034	1.1e-04	5.1e-03	1.5e-02	NA	1.6e-03

Trait associations

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17
Bipolar Disorder (2018)	0.6	0.9	3.4	0.9	-1.4	0.3	-0.5	0.5	0.4	-0.7	1.0	1.2	1.0	0.0	0.7	0.9	1.1	1.8	1.3	0.9
Bipolar Disorder or Schizophrenia	0.4	0.9	3.6	1.5	-1.0	0.3	-0.4	-0.3	-1.1	0.3	-0.9	-0.4	-1.2	-1.9	-0.2	-1.2	-0.8	-0.3	-0.8	-1.2
Depressed Affect (Nagel 2018)	0.7	1.6	4.0	-0.7	-1.4	-0.5	-0.8	0.9	-2.0	0.5	-1.4	-1.8	-1.1	-1.8	-1.0	-1.5	-1.5	-0.1	-0.8	-1.5
Depression (Nagel 2018)	1.6	2.4	9.5	0.5	-0.5	-2.2	0.8	1.3	-1.0	-0.5	-1.7	-1.9	-1.8	-3.1	-0.6	-2.0	-2.1	0.3	-0.5	-1.9
Intelligence (Savage-Jansen 2018)	0.8	2.5	12.9	-3.6	1.0	-0.3	1.7	-3.0	1.4	0.3	0.8	0.2	0.7	3.0	1.1	0.7	1.0	-0.9	0.5	0.0
Neuroticism (Nagel 2018)	2.2	5.3	14.6	1.5	-2.7	-0.5	-0.9	2.9	-3.0	-0.4	-2.6	-3.1	-2.3	-3.8	-2.0	-2.6	-3.0	0.2	-1.1	-2.1
Schizophrenia (2018)	1.3	2.7	6.0	1.1	-0.2	0.1	-0.2	-0.7	-1.6	0.9	-1.9	-1.5	-2.4	-2.5	-0.7	-2.3	-1.9	-1.9	-2.1	-2.2
Schizophrenia vs Biploar Disorder	2.7	3.5	8.5	2.2	0.6	0.5	1.9	1.0	-0.2	-0.1	-2.3	-1.7	-2.9	-2.9	-1.6	-2.9	-2.6	-1.3	-1.7	-1.6
Worry (Nagel 2018)	2.1	4.3	9.5	1.5	-2.6	-1.0	-0.4	1.5	-2.6	-0.6	-2.4	-2.9	-2.4	-3.1	-2.2	-2.7	-2.6	-0.8	-1.3	-2.0
Alzheimer’s Disease (in mother)	0.3	0.4	1.9	1.0	0.2	-1.4	0.2	0.6	-0.7	0.0	0.2	0.4	0.3	-0.3	-1.2	-0.1	0.2	0.7	-0.1	-0.2
Alzheimer’s Disease (in father)	0.9	1.0	4.8	1.3	-0.6	0.0	1.1	0.2	1.0	-1.0	0.9	0.9	0.7	1.0	2.2	0.7	0.6	0.6	1.0	1.3
Alzheimer’s Disease (including proxy)	0.2	0.2	1.5	1.2	0.1	-0.9	0.6	0.0	-0.5	-0.6	0.4	0.4	0.3	-0.1	0.1	0.2	0.2	0.2	-0.1	0.1
Crohns Disease (2017)	0.5	1.1	2.2	-1.2	-1.0	-0.6	0.1	-1.2	-1.4	0.7	-0.8	-1.2	-0.9	-1.4	-1.5	-1.0	-0.6	-1.1	-0.5	-1.3
Irritable Bowel Disease (IBD)	1.0	2.3	5.8	-1.3	-1.9	-0.2	-0.5	-1.1	-2.0	0.1	-1.5	-2.4	-1.7	-1.4	-1.5	-1.6	-1.5	-2.1	-1.3	-1.6
Ulcerative Colitis (UC)	1.0	1.9	5.3	-1.0	-2.0	0.0	-1.0	-0.6	-1.9	-0.3	-1.4	-2.3	-1.5	-1.0	-0.8	-1.4	-1.5	-1.8	-1.4	-1.1
Major Depression (MDD)	1.3	1.5	4.2	2.0	-1.6	-0.6	-1.2	1.7	-0.1	-2.0	0.7	0.5	0.7	-1.4	0.7	0.8	0.6	2.1	1.3	0.8
Reaction Time	0.9	1.7	4.5	0.1	0.2	-1.2	0.4	-0.4	0.6	0.2	-1.8	-1.6	-2.1	-1.4	-1.4	-1.9	-1.9	-1.0	-1.2	-1.6
Verbal and Numeric Reasoning (VNR)	0.3	0.7	3.2	-1.8	1.1	-0.1	1.1	-0.8	0.3	-1.0	-0.6	-1.0	-0.5	0.8	0.9	-0.6	-0.7	-0.8	-0.3	-0.4
Breast Cancer	1.0	2.5	5.4	-0.4	-0.1	0.8	-0.3	-0.9	0.9	-0.8	2.3	2.2	1.8	1.4	1.6	2.2	2.2	1.7	1.7	2.2
Ovarian Cancer	1.5	2.0	5.1	0.8	1.2	0.6	2.2	0.3	2.0	0.2	1.3	2.2	1.5	1.5	0.4	1.8	1.2	1.4	1.2	1.3
Prostate Cancer	0.3	0.4	1.3	-1.2	0.5	-0.2	-0.9	0.6	0.5	-0.6	0.4	0.3	0.4	0.1	0.9	0.5	0.4	0.7	0.8	0.4
Age at First Birth	0.8	1.2	7.5	0.2	1.9	0.0	2.7	-0.8	2.0	0.8	-0.3	0.6	-0.7	1.1	0.2	-0.8	-0.3	-0.5	0.4	0.4
Bipolar Disorder (2011)	0.4	0.4	1.4	1.2	-1.1	0.0	-0.5	0.5	-0.8	-0.7	0.0	0.3	0.3	-0.9	-0.5	0.3	0.0	0.7	-0.0	0.0
Body Mass Index (BMI) (2010)	0.8	1.0	2.5	-0.2	0.2	-1.5	-0.6	-0.2	-1.3	0.7	-1.6	-1.2	-1.2	-0.9	-0.7	-1.2	-1.3	-0.8	-1.2	-0.9
Coronary Artery Disease (CAD)	0.6	0.7	4.0	0.5	-1.8	-0.6	-0.4	-1.3	-2.0	0.6	-0.3	-0.6	-0.2	-0.0	-0.6	-0.6	-0.3	-0.1	-0.6	0.0
Crohns Disease (2012)	0.3	0.6	3.1	-1.7	-0.6	0.0	-1.0	0.3	-1.8	-1.1	0.1	-0.4	0.2	-0.5	-0.0	0.2	0.2	-0.5	-0.2	-0.0
Mean Putamen Volume	0.2	0.2	0.5	-0.3	0.7	0.6	0.1	-0.6	0.4	0.5	0.5	0.2	0.3	0.2	0.2	0.1	0.6	-0.2	0.1	0.7
Fasting Glucose	0.3	0.4	1.4	-0.5	0.2	0.7	-0.1	0.0	0.6	0.0	-0.8	-0.5	-0.9	-0.7	0.6	-0.5	-1.0	-0.4	0.0	-1.2
HbA1C	0.6	0.7	3.3	-0.1	-1.8	0.1	-1.2	-1.3	-1.7	0.5	-0.2	-0.3	0.3	-0.4	-1.1	0.2	0.1	-0.2	-0.4	-0.2
HDL Cholesterol	0.3	0.6	1.6	-0.8	0.2	1.3	-0.2	-0.8	0.5	1.1	-0.7	-0.7	-0.7	-0.1	0.4	-0.9	-0.6	-0.8	-0.4	-1.1
LDL Cholesterol	0.4	0.6	1.8	-1.1	-0.6	0.1	0.0	-0.8	-0.3	-0.1	-1.0	-0.9	-0.9	0.5	-0.8	-0.7	-0.7	-1.3	-0.5	-0.7
Lupus	0.2	0.4	2.3	-0.7	-0.2	-0.4	-0.4	0.9	0.2	-1.5	0.4	-0.0	0.4	-0.5	-0.3	0.6	0.4	0.7	0.7	0.2
Neuroticism (2016)	1.2	1.7	8.9	1.2	-3.0	0.0	-1.8	1.2	-2.1	-1.3	0.4	-0.6	0.1	-1.2	1.1	0.4	0.2	1.5	0.9	0.8
Primary Biliary Cirrhosis	0.6	0.9	4.2	-0.8	-0.5	-2.0	0.9	-1.1	0.2	1.5	-0.9	-1.0	-0.8	-0.3	-0.8	-1.1	-0.9	-0.4	-0.4	-0.4
Rheumatoid Arthritis	0.3	0.4	1.7	0.5	0.6	-1.0	-0.3	0.7	-0.2	1.0	-0.4	0.2	-0.4	-1.3	-0.1	-0.7	-0.3	0.1	-0.4	-0.5
Schizophrenia (2014)	1.8	4.0	8.4	2.1	0.0	-0.4	0.2	-0.6	-1.8	0.9	-2.5	-1.9	-2.8	-2.9	-1.7	-2.8	-2.5	-1.9	-2.4	-2.5
Triglycerides	0.3	0.5	1.3	-1.1	-0.3	-0.3	-0.7	-0.7	-0.5	0.3	1.1	0.9	0.8	0.4	0.6	1.0	1.1	0.0	0.4	-0.0
Type 2 Diabetes (T2D) (2012)	0.4	0.5	1.6	-1.3	-0.6	0.5	-1.2	-0.7	-0.8	0.8	0.4	0.7	0.7	0.3	0.4	0.0	1.1	0.0	-0.1	0.0
Ulcerative Colitis	1.1	1.6	4.7	-1.6	-0.3	0.0	0.1	-0.4	-1.0	0.0	-1.6	-2.2	-1.8	-0.7	-0.4	-1.8	-1.8	-1.8	-1.3	-1.3
Blood Eosinophil Count	0.1	0.4	2.5	-0.1	-0.9	-0.5	-1.0	1.6	-0.9	0.0	-0.1	-0.3	0.2	-0.2	-0.6	0.2	-0.2	0.9	-0.2	-0.0
Blood Platelet Count	2.8	32.7	85.2	4.1	0.6	-1.4	1.3	7.0	-1.6	-4.8	-7.5	-5.7	-7.3	-9.2	-5.6	-7.5	-7.9	-2.7	-5.8	-6.4
Blood Red Count	1.4	13.1	33.3	-5.8	2.3	-0.1	0.4	-3.9	-1.7	3.5	-4.0	-4.6	-4.0	-1.0	-2.6	-3.5	-3.7	-5.5	-4.1	-4.4
Blood White Count	0.0	0.2	1.5	-0.1	0.7	-0.6	-0.2	1.2	-0.2	-0.3	0.0	-0.4	0.0	0.1	-0.2	0.6	-0.2	-0.0	-0.4	0.1
Heel T-Score	0.6	4.6	10.2	-1.7	0.4	1.2	-1.4	0.3	-2.6	-0.1	-2.6	-2.3	-2.7	-2.0	-2.4	-2.3	-2.5	-2.6	-3.2	-2.7
BMI	0.3	1.7	7.5	0.3	-0.0	0.3	-1.2	2.7	-2.0	-1.7	-0.9	-1.8	-0.6	-1.6	-1.9	0.0	-1.2	0.1	-1.0	-0.3
Height	0.2	3.9	8.1	1.0	-1.9	0.8	0.1	-1.1	0.8	0.4	2.6	2.4	2.3	1.6	2.8	2.0	2.6	2.1	2.7	2.8
Waist Hip Ratio (WHR)	0.6	2.6	9.8	2.0	-1.0	1.9	-0.8	3.0	-1.9	-0.8	-1.2	-1.2	-0.9	-3.1	-1.8	-1.5	-1.3	1.1	-0.7	-0.5
Systolic Blood Pressure	5.8	29.1	56.2	2.0	-1.8	-0.6	-1.0	1.3	3.9	-0.5	7.4	7.0	7.2	5.7	5.6	6.7	6.9	6.9	7.2	7.5
Smoking Status	0.4	0.9	4.8	0.2	1.4	-2.2	0.6	0.8	0.7	-0.8	0.5	0.2	0.6	-0.1	0.9	0.8	0.3	1.4	0.6	1.0
Allergy or Eczema	0.6	1.6	4.6	2.1	-1.3	-0.3	1.5	1.2	0.2	-1.7	1.1	1.4	1.0	0.5	-0.0	1.0	0.8	2.1	1.2	1.3
Cardiovascular Disease	3.2	10.6	26.7	2.1	-1.6	-0.7	-0.0	2.7	2.4	-3.4	3.8	3.4	3.7	1.7	3.1	3.6	3.3	5.2	4.8	4.8
Hypothyroidism (self reported)	1.4	3.2	8.8	1.0	-0.4	0.9	-0.6	0.6	-1.9	-0.5	-2.3	-2.2	-2.1	-1.6	-2.7	-1.9	-2.2	-1.9	-3.0	-1.8
Respiratory disease	0.1	0.3	0.7	-0.8	-0.8	-0.8	-0.3	0.2	0.3	-0.5	-0.6	-0.4	-0.9	-0.5	-0.5	-0.7	-0.5	-0.2	0.0	-0.7
Type 2 Diabetes (T2D) (2018)	0.6	1.2	2.8	-1.0	-0.2	0.2	0.5	-0.4	-0.5	-0.9	-1.1	-1.7	-1.7	-1.2	-0.8	-1.4	-1.3	-1.5	-1.3	-1.0
Lung FEV1/FVC ratio	0.8	4.1	7.7	0.7	-1.1	1.3	0.7	0.6	-1.3	-0.8	-2.8	-2.6	-2.7	-2.3	-2.0	-2.5	-2.7	-2.4	-2.4	-2.5
Lung FVC	0.6	3.2	18.0	4.2	0.2	0.1	-0.7	4.2	-0.6	-2.2	0.1	0.7	0.3	-2.3	0.1	-0.9	0.1	2.2	0.2	0.4
Neuroticism	1.5	3.5	8.9	1.2	-2.5	-0.1	-1.1	2.0	-3.0	-0.8	-2.0	-2.7	-1.8	-2.9	-1.3	-2.0	-2.2	-0.4	-1.2	-1.7
Chronotype (morning person)	0.3	0.7	2.4	-0.1	-1.3	0.0	0.2	-1.5	0.6	1.4	0.6	0.4	0.8	0.7	0.4	0.7	0.6	0.7	1.3	0.6
Hair Pigment	0.2	6.7	16.0	-4.0	3.2	-1.1	0.9	-1.7	-0.3	2.2	-3.0	-2.4	-3.2	-0.5	-1.4	-2.5	-2.8	-4.0	-3.1	-3.4
Tanning	0.1	1.3	4.0	2.0	-1.6	-0.9	-0.8	1.8	-1.7	-0.3	0.5	-0.1	0.3	-1.4	-0.9	0.3	0.3	1.8	0.5	0.5
Hand grip strength (left)	2.7	7.0	13.5	-0.8	-0.7	0.8	-1.0	-0.3	2.1	-0.8	3.7	3.0	3.4	3.2	3.6	3.5	3.7	2.3	3.1	3.6
Number of treatments/medications taken	0.7	1.3	3.7	1.9	0.1	-1.1	0.9	1.5	1.4	-0.4	0.7	1.3	0.6	-0.5	0.8	0.4	0.5	1.9	1.5	1.2
Average weekly spirits intake	1.2	1.5	9.2	-0.9	2.1	0.0	2.2	1.4	3.0	-1.2	-0.5	-0.1	-0.6	-0.0	0.7	-0.1	-0.7	0.5	0.7	-0.4
Sensitivity / hurt feelings	1.4	2.5	5.5	0.5	-0.1	0.1	0.9	0.6	-0.8	0.1	-2.3	-2.2	-2.3	-2.0	-1.6	-2.2	-2.3	-1.4	-1.4	-1.8
Frequency of depressed mood in last 2 weeks	2.7	3.8	14.7	1.1	-0.1	-1.1	1.9	3.0	-1.1	-1.7	-2.2	-2.2	-2.2	-3.8	-1.3	-2.1	-2.5	0.2	-0.8	-1.7
Hearing difficulty/problems: Yes	0.7	1.1	2.2	-0.0	-1.2	0.4	0.5	1.3	-0.8	-1.4	-1.2	-1.4	-0.8	-1.4	-1.5	-0.7	-1.2	-0.2	-0.8	-1.0
Relative age of first facial hair	0.7	1.5	5.5	2.3	0.0	0.9	0.3	2.0	0.6	-1.3	1.1	1.8	1.1	0.4	0.6	0.9	1.1	1.5	0.6	1.4
Other serious medical condition/disability diagnosed by doctor	0.9	1.1	6.2	0.4	1.4	-1.9	1.1	2.5	0.8	-1.2	-0.1	0.4	-0.1	-1.0	-0.8	-0.5	-0.3	1.2	0.1	-0.6
Ever used hormone-replacement therapy (HRT)	0.6	0.8	3.2	-1.2	1.8	1.1	1.4	-0.5	1.3	1.4	-0.1	0.7	-0.2	0.8	0.4	-0.0	-0.0	-0.5	-0.1	-0.7
Ever had hysterectomy (womb removed)	0.3	0.3	2.4	-0.1	0.9	0.3	1.5	0.3	0.9	-0.5	-0.3	-0.4	-0.2	-0.1	-0.2	-0.2	-0.2	0.0	-0.1	-0.1
Systolic blood pressure, automated reading	5.8	16.8	32.1	0.5	-0.2	-1.1	-2.1	0.7	1.9	0.4	5.6	5.6	5.7	4.4	4.6	5.6	5.6	4.7	5.0	5.4
Eye problems/disorders: Diabetes related eye disease	0.3	0.4	1.3	0.5	0.5	0.3	0.5	1.0	0.4	-1.1	-0.7	-0.3	-0.5	-0.7	-0.3	-0.6	-0.7	-0.1	-0.5	-0.8
Angina	1.1	1.5	3.0	-0.5	1.6	0.6	1.2	0.8	1.7	0.9	-1.7	-0.5	-1.7	-1.5	-0.1	-1.7	-1.6	-0.8	-0.8	-1.2
Medication for hormone replacement therapy	0.4	0.5	2.8	-1.7	0.7	0.6	0.2	-0.5	1.3	-0.1	0.6	0.2	0.4	0.8	0.6	0.7	0.5	-0.1	0.6	-0.1
Vitamin and mineral supplements	1.4	1.9	7.3	1.3	-1.6	-1.6	-0.4	1.9	-0.9	-0.4	-1.5	-1.5	-1.2	-2.7	-1.0	-1.3	-1.7	0.7	-0.4	-1.2
Supplements: Zinc	2.4	2.6	6.8	0.9	0.8	0.4	-0.0	-0.2	0.1	0.7	2.0	2.6	2.1	1.8	2.1	1.8	1.8	1.9	2.2	2.3
Medication: Co-codamol	0.8	0.9	2.6	-0.6	0.7	0.9	-0.6	0.8	0.8	-0.3	1.0	0.7	1.1	0.5	1.4	1.3	0.9	1.2	1.6	0.3
Medication: Metformin	0.6	0.9	2.0	0.8	0.2	-0.6	0.9	0.8	0.0	-1.3	-1.1	-1.4	-1.3	-1.2	-1.0	-1.4	-1.2	-0.4	-0.6	-0.3
Diabetes (father)	1.0	1.3	2.7	-1.4	0.6	1.5	-0.1	-1.3	-0.2	0.5	-1.3	-1.6	-1.4	-1.1	0.3	-1.0	-1.3	-1.5	-0.6	-1.4
Diabetes (mother)	0.3	0.4	1.4	-0.6	-0.1	0.8	-0.8	-0.5	0.4	-0.6	0.6	0.3	0.7	1.2	0.7	0.7	0.6	0.1	0.4	-0.1
Severe depression (siblings)	0.4	0.4	1.6	0.0	-0.3	0.7	0.4	0.8	-0.6	-0.2	-0.7	-1.0	-0.6	0.1	0.9	-0.9	-0.7	-0.5	-1.3	-0.3
Pack years adult smoking proportion	1.0	1.5	3.1	-1.7	0.4	0.5	0.3	-0.1	-0.2	1.1	-1.7	-1.7	-1.8	-1.6	-0.9	-1.6	-1.6	-1.1	-0.7	-1.6
Impedance of leg (right)	0.1	0.6	2.8	1.2	-0.3	-0.6	0.9	0.7	0.9	0.5	0.4	0.9	0.5	0.1	0.4	0.2	0.2	1.7	1.4	0.2
Leg fat-free mass (left)	0.1	0.4	2.1	-0.2	-0.5	1.1	-0.5	0.8	-1.1	-1.4	0.1	-0.8	0.1	-0.7	-0.0	0.6	0.1	-0.2	-0.3	0.6
Trunk fat percentage	0.5	2.1	8.9	1.5	-0.2	-0.1	-1.1	3.0	-2.0	-2.1	-1.0	-1.4	-0.8	-2.3	-1.9	-0.3	-1.1	0.4	-0.9	-0.6
Hand grip strength (right)	2.7	7.3	15.5	-1.6	-1.6	1.2	-1.7	-2.2	1.4	-0.1	3.7	2.6	3.5	3.6	3.6	3.5	3.9	1.4	2.5	3.6
Townsend deprivation index at recruitment	0.7	1.0	2.7	-0.5	0.4	1.6	-0.3	1.4	-1.3	-1.0	-1.2	-1.6	-0.6	-1.6	-0.5	-0.4	-1.1	-0.2	-0.6	-0.6
Current tobacco smoking	0.4	0.7	3.4	-1.7	1.8	0.3	0.3	0.5	0.9	-0.3	0.6	0.1	0.9	0.1	0.2	1.0	0.5	1.0	0.5	0.4
Average weekly fortified wine intake	2.8	3.3	10.4	2.2	-2.3	-1.4	0.4	1.1	1.3	-1.0	1.7	1.6	1.9	0.8	0.9	1.5	1.5	2.8	3.2	2.7
Maternal smoking around birth	0.4	0.6	3.4	-1.2	0.4	0.7	-0.4	1.9	0.5	-0.9	0.4	0.2	0.6	0.6	1.0	0.9	0.4	0.5	0.8	0.3
Fed-up feelings	0.8	1.5	6.5	-0.1	-1.2	1.2	-0.3	0.7	-2.5	0.9	-1.0	-1.3	-0.8	-2.0	-1.9	-1.1	-1.0	-0.1	-0.9	-1.1
Frequency of unenthusiasm / disinterest in last 2 weeks	1.7	2.3	6.7	-0.5	1.5	-2.2	1.6	0.2	-0.1	1.0	-1.7	-1.3	-1.8	-2.6	-0.7	-2.1	-1.8	-0.6	-0.8	-2.1
Relative age voice broke	0.2	0.3	1.6	0.2	-0.0	1.3	-0.1	0.2	0.5	0.2	0.5	0.8	0.4	0.4	-0.1	0.2	0.4	0.5	1.1	0.2
Taking other prescription medications	1.2	1.9	4.4	-1.4	-0.3	-1.2	-0.5	0.5	-0.4	-0.6	-1.6	-1.9	-1.6	-1.7	-1.6	-1.8	-1.6	-1.3	-1.3	-2.1
Age when periods started (menarche)	0.3	0.6	3.5	0.7	0.3	0.8	1.5	-1.9	0.6	1.3	-0.1	-0.2	-0.4	0.2	-0.2	-0.8	-0.1	-0.5	-0.0	0.9
Bilateral oophorectomy (both ovaries removed)	0.4	0.4	1.5	1.1	-0.7	1.2	-0.2	1.0	-0.7	-0.7	0.0	-0.1	0.1	-1.1	0.1	-0.1	0.0	0.8	0.4	0.0
Heel bone mineral density (BMD) T-score, automated (left)	0.6	1.5	7.5	-2.6	0.9	-0.5	-0.9	-2.7	0.1	1.7	-0.6	-1.0	-0.8	0.7	-0.0	-0.6	-0.5	-1.6	-0.3	-0.9
Tinnitus: Yes, but not now, but have in the past	0.3	0.3	1.1	0.9	0.3	0.4	0.3	0.9	0.1	0.5	-0.2	0.3	-0.1	-0.9	0.4	-0.6	-0.3	1.1	0.5	0.2
Qualifications: CSEs or equivalent	0.5	0.7	2.0	0.7	0.5	0.2	0.4	1.2	-0.8	-0.6	-1.1	-0.6	-0.6	-1.3	-0.9	-0.6	-1.0	-0.4	-0.8	-1.4
Serious illness, injury or assault to yourself	1.5	1.9	10.0	0.8	1.1	-0.3	0.2	2.0	-0.1	-0.4	-1.7	-1.0	-1.5	-3.2	-1.3	-1.5	-1.8	0.4	-0.7	-1.3
High blood pressure	3.9	10.8	30.1	3.2	-2.5	-0.0	0.2	3.0	2.8	-3.0	3.5	3.3	3.5	0.7	2.7	3.1	3.1	5.5	5.2	4.6
Hayfever, allergic rhinitis or eczema	0.2	0.5	3.3	1.8	-1.3	-0.3	0.8	0.9	-0.2	-1.0	-0.2	0.1	-0.3	-0.4	-0.7	-0.1	-0.3	0.7	0.0	-0.1
Multivitamins +/- minerals	1.6	2.1	7.5	-1.0	0.6	2.2	-0.6	-1.7	0.1	0.0	1.7	1.4	1.4	2.7	1.4	1.8	1.7	-0.5	0.6	1.6
Stomach or abdominal pain in last month	0.8	1.0	3.3	-0.3	-0.2	1.0	-0.2	1.3	-1.0	-0.4	-1.1	-1.3	-0.9	-1.8	-1.3	-0.9	-1.1	-0.7	-0.9	-1.4
Supplements: Glucosamine	1.7	2.2	6.6	-0.8	2.4	2.0	0.1	-1.0	2.6	1.4	1.1	1.3	1.1	2.0	1.9	0.8	1.1	0.4	1.6	1.4
Diverticular disease/diverticulitis (self-reported)	1.1	1.4	6.5	0.9	0.0	-1.0	0.1	2.5	-0.4	-2.5	-0.9	-0.9	-0.8	-1.7	-0.6	-0.5	-1.2	1.0	0.1	-0.2
Medication: Atenolol	1.0	1.3	4.5	0.3	-2.1	-1.0	-0.5	-0.1	0.3	-0.9	1.5	1.1	1.3	0.7	-0.4	1.4	1.4	1.2	1.1	1.6
Medication: Levothyroxine sodium	2.0	3.4	10.0	0.6	-0.3	0.2	0.5	0.1	-1.0	-0.4	-2.5	-2.5	-2.4	-1.9	-3.2	-2.3	-2.4	-1.9	-2.5	-2.0
Sitting height	0.1	0.7	4.0	0.9	-1.2	0.2	1.1	0.0	0.2	-2.0	0.6	0.4	0.5	0.3	0.5	0.8	0.3	1.0	1.0	1.0
Chronic bronchitis/emphysema (father)	1.4	1.6	3.1	1.0	-0.0	1.3	-0.5	1.6	-0.8	-1.6	-1.4	-1.3	-1.5	-1.8	-1.3	-1.2	-1.3	-0.7	-1.3	-1.5
High blood pressure (mother)	2.2	3.1	8.3	1.2	-0.6	0.2	-1.6	1.7	0.4	-1.1	2.3	2.2	2.5	0.9	-0.0	2.2	2.3	2.9	2.0	2.1
Body mass index (BMI)	0.3	1.4	5.0	0.3	-0.2	-0.1	-1.4	2.2	-1.9	-1.7	-0.7	-1.4	-0.5	-1.7	-1.6	0.0	-0.8	0.1	-1.0	-0.4
Impedance of leg (left)	0.1	0.5	1.7	0.8	0.1	-0.9	1.3	0.5	1.2	0.4	0.3	0.9	0.4	0.3	0.1	0.1	0.1	1.3	1.1	0.0
Leg predicted mass (left)	0.1	0.5	2.1	-0.3	-0.6	1.1	-0.6	0.7	-1.1	-1.4	0.2	-0.8	0.2	-0.6	0.0	0.7	0.2	-0.2	-0.2	0.7
Trunk fat mass	0.4	1.7	6.7	1.3	-0.2	0.3	-0.8	2.6	-1.9	-2.0	-0.8	-1.3	-0.7	-2.1	-1.6	-0.1	-0.9	0.3	-0.8	-0.2
Waist circumference	0.5	1.8	7.8	0.3	-0.3	0.4	-0.8	2.8	-1.9	-2.1	-0.9	-1.4	-0.7	-2.2	-1.7	-0.2	-1.0	0.6	-0.7	-0.4
Number of incorrect matches in round	0.4	0.7	3.3	-0.2	-0.3	-1.8	1.0	-1.7	0.8	1.2	0.5	1.1	0.2	0.4	0.7	0.1	0.7	-0.2	0.3	0.1
Past tobacco smoking	0.2	0.4	2.0	-0.1	-1.4	0.8	-0.2	-1.2	-0.5	1.2	0.1	0.0	0.2	0.6	0.3	0.3	0.2	-0.4	0.4	-0.2
Alcohol usually taken with meals	0.2	0.4	1.4	-0.4	-0.2	0.6	0.7	0.2	1.2	-0.1	0.2	1.2	0.3	1.1	-0.4	0.6	0.2	0.3	0.7	-0.0
Nervous feelings	1.4	2.6	8.5	0.3	-1.9	-2.7	-0.7	-0.7	-2.9	1.2	-1.4	-1.7	-1.5	-1.8	-1.6	-1.8	-1.2	-1.3	-1.4	-1.3
Frequency of tenseness / restlessness in last 2 weeks	1.5	2.3	10.2	0.9	-0.5	-0.5	1.8	1.5	-0.7	-0.3	-1.8	-1.8	-1.9	-3.2	-1.0	-2.0	-2.0	-0.1	-0.4	-1.2
Hearing difficulty/problems with background noise	1.1	1.8	7.4	-0.3	-2.0	-0.3	-0.2	1.8	-1.1	-2.7	-1.3	-1.5	-1.1	-1.9	-1.5	-0.4	-1.4	-0.2	-0.6	-1.4
Hair/balding pattern: Pattern 2	2.1	2.7	5.4	-0.6	-0.7	1.5	-1.1	-1.8	0.5	1.4	2.2	1.8	2.0	2.2	1.9	1.7	2.3	0.7	1.4	2.3
Had menopause	1.7	2.1	11.7	0.5	3.4	0.4	2.3	-0.2	1.4	1.5	-1.4	-0.2	-1.4	-0.0	-0.4	-1.7	-1.4	-1.5	-1.6	-0.8
Had other major operations	0.4	0.4	1.8	-1.3	1.3	1.2	0.5	-0.0	0.9	0.2	0.3	-0.1	0.5	0.2	0.2	0.1	0.4	0.7	0.6	0.2
Forced vital capacity (FVC)	0.5	2.0	9.1	3.0	-0.8	0.4	0.1	3.0	0.0	-2.3	0.4	0.6	0.5	-1.5	1.0	0.1	0.3	1.9	1.0	0.7
Heel bone mineral density (BMD) T-score, automated (right)	1.2	2.7	7.4	-2.4	0.9	-0.5	-0.6	-2.0	-0.4	0.8	-1.9	-2.1	-2.0	-0.0	-0.9	-1.9	-1.7	-2.7	-1.6	-2.1
Ever unenthusiastic/disinterested for a whole week	1.5	1.9	5.6	0.8	-1.8	-0.0	-1.4	1.7	-1.8	-2.4	-1.1	-1.1	-1.0	-1.9	-1.4	-1.1	-1.1	-0.6	-1.1	-1.1
Qualifications: None of the above	1.6	3.4	11.7	-0.9	1.9	-0.8	-0.9	-1.6	-1.0	3.4	-1.9	-1.6	-1.8	-0.2	-2.1	-1.7	-1.6	-2.7	-2.6	-1.9
Financial difficulties in last 2 years	0.2	0.3	0.7	-0.2	0.2	-0.6	-0.6	0.8	-0.6	-0.6	0.3	-0.3	0.7	-0.6	0.0	0.7	0.3	0.8	0.5	0.1
Mouth/teeth dental problems	0.5	0.7	2.8	0.3	-0.5	-0.2	-0.1	0.9	-1.4	-0.9	-0.8	-1.1	-0.7	-1.7	-0.0	-0.4	-0.8	-0.4	-1.3	-0.9
Heart attack	0.9	1.2	6.2	-2.5	0.6	1.1	1.0	-1.2	2.1	0.7	-0.5	-0.5	-0.9	1.0	0.3	-0.8	-0.5	-1.0	0.2	-0.9
Allergy	0.3	0.6	1.9	-1.4	0.6	0.2	-1.0	-1.0	-0.1	0.3	0.9	0.4	0.9	0.9	1.0	0.8	1.0	-0.4	0.3	0.7
Pain all over the body in last month	0.2	0.3	1.8	0.2	0.0	-0.0	-0.5	-1.0	-0.4	1.3	-0.2	-0.0	-0.3	0.1	-0.8	-0.1	-0.3	-0.1	-0.2	-0.0
Diabetes (self-reported)	0.8	1.2	3.1	0.1	0.5	0.1	1.1	-0.0	0.3	-0.4	-1.4	-1.5	-1.8	-1.4	-0.8	-1.4	-1.5	-1.5	-1.1	-1.0
Hayfever/allergic rhinitis (self-reported)	0.7	0.9	3.8	0.2	-0.0	-2.0	0.7	-1.5	0.8	-0.0	1.1	1.0	0.9	1.0	0.5	0.9	1.3	0.0	0.6	0.7
Medication: Ramipril	0.4	0.5	1.6	0.5	-0.9	-1.3	0.3	0.3	-1.1	0.6	-0.7	-1.0	-0.7	-1.1	-0.2	-0.6	-0.6	-0.2	-0.6	-0.4
Medication: Simvastatin	0.5	0.7	3.6	1.8	0.2	-1.9	0.7	1.1	0.9	-0.7	-0.2	0.2	-0.4	-1.1	-0.1	-0.4	-0.3	0.8	0.3	0.5
Fluid intelligence score	0.2	0.5	2.6	-1.2	0.5	0.3	1.4	-0.4	0.3	-1.6	0.0	-0.3	-0.1	0.7	0.7	-0.2	-0.1	-0.3	0.2	0.2
Illnesses of siblings	0.5	0.6	3.5	0.3	0.3	-0.2	0.0	-0.8	-0.6	1.9	-0.6	-0.6	-0.8	-0.2	-1.4	-1.1	-0.7	-0.5	-0.9	-0.4
Neuroticism score	2.4	4.9	12.5	0.5	-1.6	0.0	-0.5	1.3	-3.0	0.4	-2.8	-3.4	-2.8	-3.5	-1.9	-3.1	-2.9	-1.2	-1.5	-2.2
Weight	0.2	0.8	3.2	0.6	-0.4	0.3	-0.7	1.7	-1.5	-1.8	-0.1	-0.9	0.0	-1.2	-0.8	0.6	-0.2	0.5	-0.3	0.5
Impedance of arm (right)	0.0	0.2	0.8	0.9	-0.7	-0.4	-0.1	-0.1	0.0	-0.2	-0.1	0.3	-0.1	-0.4	-0.5	-0.3	-0.0	0.3	0.5	-0.8
Arm fat percentage (right)	0.4	1.8	5.7	1.1	-0.7	-0.0	-1.7	2.4	-2.2	-1.8	-0.6	-1.3	-0.5	-1.9	-2.0	0.0	-0.8	0.4	-0.8	-0.4
Trunk fat-free mass	0.1	0.7	2.3	-0.1	-0.6	0.9	0.2	0.1	-0.4	-1.2	1.1	0.2	1.0	0.4	0.8	1.3	1.0	0.6	0.5	1.5
Hip circumference	0.2	0.7	4.6	-0.3	-0.4	-0.6	-0.6	1.6	-1.2	-2.1	-0.1	-0.8	-0.0	-0.8	-1.0	0.7	-0.2	0.4	0.0	0.1
Time employed in main current job	1.2	1.3	8.7	0.1	3.0	-0.4	0.6	0.8	-0.1	1.9	-1.0	0.0	-0.9	-1.6	-0.5	-1.4	-1.0	-0.1	-0.6	-1.1
Alcohol intake versus 10 years previously	0.7	1.1	2.5	-0.4	0.8	0.8	0.8	0.5	-0.4	-0.4	-1.4	-1.6	-1.4	-0.9	-0.9	-1.6	-1.4	-1.2	-0.9	-1.2
Father’s age at death	1.2	1.6	4.1	2.0	0.1	1.5	1.1	1.0	-1.2	-0.1	-1.3	-0.9	-1.3	-1.2	-1.9	-1.8	-1.3	-0.6	-1.0	-0.9
Worrier / anxious feelings	1.8	3.4	8.2	1.5	-2.9	-0.9	-0.8	1.9	-2.6	-1.2	-1.8	-2.4	-1.9	-2.9	-1.6	-2.1	-1.9	-0.4	-0.6	-1.3
Frequency of tiredness / lethargy in last 2 weeks	3.4	5.6	13.7	-1.3	0.9	-1.4	1.5	1.0	-0.5	-0.4	-3.2	-3.0	-3.3	-3.7	-2.4	-3.5	-3.2	-1.6	-1.6	-3.0
Falls in the last year	2.4	3.2	12.3	-0.0	-0.4	0.1	-1.0	1.4	-2.5	-0.3	-2.0	-2.3	-1.9	-3.5	-1.9	-1.6	-2.1	-0.7	-1.7	-2.3
Hair/balding pattern: Pattern 3	0.7	1.1	3.1	-0.2	-0.5	-0.0	-0.8	0.9	-1.7	-0.6	-1.2	-1.2	-1.1	-1.2	-0.4	-0.7	-1.3	-0.7	-1.3	-1.7
Number of live births	0.3	0.5	2.5	1.6	0.5	0.1	0.6	1.5	-0.8	0.2	0.4	1.0	0.4	-0.0	0.0	0.6	0.3	0.6	-0.2	0.3
Forced expiratory volume in 1-second (FEV1)	0.6	1.9	7.8	2.5	-1.3	1.0	0.1	2.8	-0.9	-2.4	-0.7	-0.7	-0.6	-2.4	-0.0	-0.9	-0.8	0.6	-0.0	-0.5
Pulse rate	0.6	1.1	4.0	-1.4	0.0	-0.3	-0.9	-2.0	1.2	0.8	0.7	0.7	0.8	1.9	0.7	1.1	0.8	-0.3	1.0	0.6
Happiness	2.0	2.5	5.8	0.5	-2.4	-1.0	0.1	0.6	-1.7	-1.1	-2.0	-1.7	-1.9	-2.3	-1.9	-2.0	-2.1	-0.2	-0.6	-1.6
Noisy workplace	0.8	1.0	5.9	0.5	-0.7	-0.5	-2.4	0.6	-0.9	-0.2	1.0	0.5	1.5	0.6	0.0	1.6	1.1	0.8	0.5	0.8
Qualifications: A levels/AS levels or equivalent	0.6	1.4	4.5	-0.3	0.5	1.5	1.2	-0.0	1.6	-0.2	1.2	1.3	0.8	1.3	2.1	0.6	1.1	1.1	1.8	1.3
Serious illness, injury or assault of a close relative in last 2 years	0.6	0.7	4.1	2.0	0.1	0.0	0.6	0.8	-0.9	-0.7	-0.7	-0.2	-0.7	-1.4	-0.4	-0.9	-0.8	0.1	-0.7	-0.0
Mouth/teeth dental problems: Dentures	0.7	1.1	6.6	-1.3	0.6	-1.6	0.8	-2.6	0.8	1.2	0.4	0.1	-0.0	1.6	0.5	0.2	0.4	-1.0	0.2	0.6
Asthma	0.3	0.6	1.6	-0.5	-0.3	0.4	1.1	-0.1	0.9	-0.2	-1.0	-0.8	-1.2	-0.5	-0.3	-1.2	-0.9	-0.9	-0.4	-0.7
Medication: Ibuprofen (e.g. Nurofen)	1.1	1.4	3.8	1.2	-0.1	0.9	0.5	1.4	0.4	-0.4	1.3	1.5	1.3	0.9	1.1	1.3	1.0	2.0	1.7	1.2
Medication: Cholesterol lowering	1.3	2.0	8.7	2.2	-0.5	-1.5	-0.2	1.6	-0.5	-1.0	-1.4	-0.9	-1.6	-3.0	-1.5	-1.8	-1.5	0.3	-0.5	-0.5
Depression (self-reported)	4.0	4.8	10.0	0.9	-1.9	-0.1	0.0	1.5	-2.0	-2.8	-2.7	-3.2	-2.5	-2.6	-2.5	-2.5	-2.9	-1.4	-2.2	-2.1
Medication: Lansoprazole	1.9	2.2	5.7	-0.4	1.8	-0.6	-0.1	0.7	-0.8	-0.3	-1.7	-1.5	-1.9	-2.4	-1.9	-2.0	-1.9	-1.3	-1.8	-1.4
Prospective memory result	0.5	0.6	3.6	-0.0	0.8	-1.1	0.8	-0.2	1.5	1.9	-0.2	0.4	0.2	-0.1	-0.2	-0.5	-0.1	0.6	0.9	-0.8
Lung cancer (father)	0.4	0.5	2.8	0.9	0.3	-1.7	1.4	0.8	-0.5	-0.0	-0.3	-0.2	0.1	0.1	-0.7	0.2	-0.4	0.8	0.0	0.6
Illnesses of mother	1.1	1.4	3.1	-1.3	-0.4	1.3	1.4	-1.1	0.3	0.8	-1.4	-1.8	-1.7	-0.8	0.4	-1.4	-1.5	-1.4	-0.8	-0.7
Forced expiratory volume in 1-second (FEV1), Best measure	0.5	1.5	7.7	1.5	-1.8	1.4	-0.3	2.4	-0.1	-2.8	0.3	0.2	0.4	-1.1	0.4	0.2	0.3	1.1	1.1	-0.1
Pulse wave Arterial Stiffness index	1.1	1.3	4.9	-1.1	1.8	0.4	-0.5	1.0	0.9	0.7	-1.4	-0.6	-1.4	-0.9	-0.2	-1.1	-1.3	-1.2	-1.2	-2.2
Impedance of arm (left)	0.0	0.2	1.4	1.2	-0.4	-0.1	-0.3	0.1	-0.1	0.2	-0.1	0.4	-0.0	-0.6	-0.4	-0.5	0.0	0.3	0.4	-0.6
Arm fat mass (right)	0.3	1.2	4.2	0.6	-0.5	0.1	-1.1	2.0	-1.8	-1.9	-0.4	-1.2	-0.4	-1.7	-1.5	0.2	-0.5	0.3	-0.7	-0.0
Trunk predicted mass	0.1	0.6	2.1	-0.1	-0.5	0.9	0.2	0.2	-0.3	-1.3	1.0	0.2	1.0	0.4	0.8	1.2	0.9	0.5	0.4	1.4
Standing height	0.1	1.2	3.0	0.7	-0.8	0.9	1.2	-0.6	0.7	-0.8	1.3	0.9	1.1	0.7	1.4	1.2	1.2	1.1	1.7	1.7
Length of working week for main job	1.5	1.7	3.7	-1.3	1.2	1.3	-0.4	0.8	0.5	0.5	-1.8	-1.6	-1.5	-1.6	-1.3	-1.8	-1.9	-0.2	-0.4	-1.8
Exposure to tobacco smoke at home	1.1	1.3	4.4	1.3	-1.6	0.0	-1.3	1.3	0.0	-0.5	0.9	0.9	0.8	-0.8	1.1	1.1	0.7	2.1	1.5	0.8
Breastfed as a baby	0.7	0.9	5.7	2.4	-0.3	0.2	0.6	0.8	-1.2	0.5	-0.8	-0.8	-0.7	-1.3	-0.3	-1.3	-1.0	0.5	-0.6	-0.0
Tense / ‘highly strung’	2.8	4.7	16.6	1.9	-0.8	0.5	0.3	3.0	-1.7	0.4	-2.6	-2.3	-2.4	-4.1	-2.3	-3.4	-2.7	-0.0	-1.2	-1.6
Seen doctor (GP) for nerves, anxiety, tension or depression	1.6	2.5	8.2	2.0	-1.6	-0.3	1.0	2.9	0.2	-2.8	-1.0	-1.0	-1.2	-2.8	-1.2	-1.5	-1.4	0.9	0.3	-0.7
Hair/balding pattern: Pattern 4	1.6	3.9	10.0	-2.2	1.7	-0.8	0.1	-1.0	-0.5	-1.0	-2.4	-2.5	-2.5	-1.3	-1.6	-2.0	-2.2	-3.2	-2.6	-2.7
Birth weight of first child	0.9	1.7	4.4	0.0	-0.8	0.5	0.0	0.0	-1.3	-0.8	-1.6	-1.5	-1.6	-1.4	-2.1	-1.2	-1.5	-1.8	-1.9	-1.4
Peak expiratory flow (PEF)	0.6	1.4	6.7	1.6	-1.4	0.4	-1.8	2.0	-1.0	-2.6	-0.1	-0.5	0.1	-1.4	0.1	0.3	-0.2	1.0	0.4	0.4
Pulse wave reflection index	0.7	0.9	6.0	0.9	0.9	2.0	0.5	2.5	1.0	-0.3	-0.1	0.5	-0.2	-0.4	0.8	-0.1	-0.2	1.1	0.4	0.2
Ever highly irritable/argumentative for 2 days	0.4	0.5	1.6	0.5	-0.1	-0.3	-0.4	1.1	-1.3	-0.9	-0.7	-0.7	-0.4	-1.1	-1.0	-0.5	-0.7	0.0	-0.6	-0.5
Loud music exposure frequency	0.7	0.7	2.3	-0.2	-0.5	0.3	-0.3	1.1	0.7	-0.9	0.8	0.7	0.9	0.8	-0.2	1.2	0.7	1.4	1.5	0.3
Qualifications: O levels/GCSEs or equivalent	0.8	1.2	2.5	-0.4	0.0	1.1	0.2	-0.0	0.2	-1.0	1.5	1.1	1.4	0.9	1.4	1.6	1.5	1.1	1.4	1.3
Mouth/teeth dental problems: Bleeding gums	1.1	1.4	3.5	-0.6	-0.6	1.3	-0.4	-0.6	0.2	0.5	-1.6	-1.6	-1.7	-0.6	-1.4	-1.9	-1.5	-1.1	-0.6	-1.7
Blood clot in the leg (DVT)	0.9	1.1	3.3	1.7	1.2	0.1	1.3	1.4	0.9	1.2	0.3	1.2	0.4	-0.2	0.5	0.3	0.2	1.8	1.3	1.4
Medication: Paracetamol	0.8	1.3	5.0	2.2	-1.0	-0.9	-0.6	1.6	-0.6	-1.6	0.7	1.4	0.9	-0.7	0.3	1.0	0.8	1.6	0.9	0.7
Headache pain in last month	1.4	2.4	6.0	1.4	-2.4	-0.5	-0.0	2.1	-1.2	-2.4	-1.4	-1.7	-1.2	-2.3	-2.0	-1.5	-1.6	0.4	-0.3	-1.2
Medication for cholesterol, blood pressure or diabetes	1.1	1.8	7.2	-2.6	1.1	2.7	0.2	-1.6	0.3	0.5	0.6	0.0	0.6	2.3	1.0	0.7	0.8	-1.7	-0.5	-0.4
Glaucoma (self-reported)	1.2	1.4	7.4	1.7	-0.2	0.4	-0.7	2.7	-1.3	-2.1	-0.0	-0.5	0.1	-2.0	-0.9	-0.3	-0.2	1.3	0.1	0.5
Gout (self-reported)	1.8	2.4	7.0	2.3	-1.1	1.4	-0.3	2.6	-0.5	-2.3	1.4	1.2	1.5	-0.1	1.3	1.5	1.1	2.0	1.3	1.8
Hypothyroidism/myxoedema (self-reported)	1.7	3.2	6.4	1.3	-0.6	0.9	-0.1	0.9	-1.9	-1.0	-2.4	-2.3	-2.1	-1.8	-2.3	-1.8	-2.4	-1.6	-2.5	-2.0
Medication: Amlodipine	0.7	0.9	4.6	1.4	-0.9	-2.1	-0.1	0.8	0.8	-0.7	0.4	0.5	0.7	0.2	-1.2	0.5	0.3	1.5	1.2	0.6
Medication: Ventolin 100micrograms inhaler	1.2	1.5	4.0	-0.2	0.2	0.8	0.2	-0.0	-0.7	0.4	-1.6	-1.4	-2.0	-1.8	-0.6	-1.9	-1.8	-1.3	-1.4	-1.3
Birth weight	0.6	1.4	4.0	0.5	0.9	0.0	0.1	2.0	-1.4	-0.3	-1.5	-0.7	-1.2	-1.8	-1.1	-1.1	-1.6	-0.3	-1.5	-1.3
Chronic bronchitis/emphysema (mother)	0.4	0.5	1.3	-0.4	0.9	-0.6	0.2	-0.6	0.4	0.6	-0.8	-1.1	-0.8	-0.6	0.6	-0.9	-0.8	-0.7	-0.2	-0.6
High blood pressure (siblings)	1.3	1.8	3.5	0.1	0.5	0.2	0.1	0.9	1.5	-1.3	1.5	1.8	1.8	1.1	1.2	1.7	1.5	1.8	1.9	1.7
Forced vital capacity (FVC), Best measure	0.7	2.6	7.5	2.0	-1.8	1.3	-0.1	2.3	0.5	-2.7	1.5	1.4	1.5	-0.1	1.3	1.2	1.4	2.2	2.0	1.2
Body fat percentage	0.5	2.0	8.8	1.2	-0.2	0.2	-1.1	3.0	-1.9	-1.9	-1.0	-1.4	-0.8	-2.1	-2.0	-0.2	-1.1	0.4	-0.9	-0.6
Leg fat percentage (right)	0.4	1.4	8.2	1.1	-0.4	0.4	-1.3	2.9	-1.8	-1.5	-0.6	-1.2	-0.3	-1.6	-1.3	0.2	-0.8	0.7	-0.6	-0.3
Arm fat-free mass (right)	0.1	0.6	2.8	-0.5	-0.1	0.8	0.2	0.4	-0.3	-1.2	0.9	0.1	0.9	0.5	0.9	1.3	0.8	0.4	0.3	1.7
Exposure to tobacco smoke outside home	0.4	0.5	1.5	-0.9	0.2	1.2	-1.2	0.5	0.1	-0.6	0.9	0.5	1.0	0.1	0.2	0.9	1.0	0.5	-0.1	0.3
Comparative body size at age 10	0.3	1.0	4.0	-1.2	0.9	1.1	-1.4	0.2	-2.0	0.4	-0.5	-0.9	-0.3	-0.0	-1.1	-0.1	-0.5	-1.0	-1.5	-0.9
Number of full brothers	0.4	0.5	3.3	-0.1	1.8	0.8	-0.4	0.2	-0.3	1.4	-0.5	-0.3	-0.4	-0.1	0.2	-0.2	-0.5	-0.7	-0.9	-0.1
Worry too long after embarrassment	1.9	3.1	8.8	2.1	-2.0	-0.2	-1.7	2.0	-1.6	-0.9	-2.1	-2.3	-1.9	-3.0	-0.7	-2.0	-2.2	-0.4	-0.6	-1.7
Seen a psychiatrist for nerves, anxiety, tension or depression	1.4	1.8	9.0	1.9	-0.9	0.1	-0.0	3.0	-0.7	-2.4	-1.0	-0.9	-0.9	-2.1	-0.5	-1.1	-1.4	0.9	-0.2	-0.0
Wheeze or whistling in the chest in last year	0.6	1.1	4.1	-0.1	0.2	-0.3	0.7	2.0	0.7	-1.5	-1.1	-0.9	-1.1	-1.7	-1.2	-0.9	-1.4	0.4	-0.3	-1.1
Number of children fathered	1.2	1.4	3.4	1.2	-1.6	1.4	-1.5	1.5	0.1	-1.7	1.2	1.1	1.2	0.3	0.2	1.9	0.9	1.0	0.7	1.1
Reason for reducing amount of alcohol drunk: Health precaution	0.8	1.0	5.7	2.4	0.3	-0.1	-0.4	2.0	-1.4	-0.8	-0.7	-0.3	-0.5	-1.1	-0.0	-0.5	-0.8	0.4	-0.7	-0.3
Age at first live birth	1.2	2.1	4.5	1.6	-1.0	0.5	0.4	0.1	0.5	0.1	1.6	2.1	1.8	1.7	1.2	1.4	1.6	1.9	2.1	1.9
Pulse wave peak to peak time	1.2	1.4	5.3	1.1	-1.8	-0.7	0.6	-1.1	-0.7	-0.6	1.4	0.6	1.3	0.9	0.3	1.0	1.3	1.2	1.2	2.3
Health satisfaction	1.2	1.6	7.5	0.8	-0.5	-0.5	0.7	0.4	-0.5	-1.7	-1.3	-1.5	-1.3	-1.6	-2.7	-1.5	-1.3	-0.8	-0.9	-0.7
Shortness of breath walking on level ground	1.5	1.8	3.6	-0.8	1.9	-1.5	1.2	-0.3	1.2	0.3	-1.7	-1.5	-1.6	-1.3	-1.3	-1.8	-1.7	-1.4	-0.8	-1.3
Qualifications: College or University degree	1.2	3.9	9.3	1.2	-1.9	1.6	1.0	0.4	1.3	-1.0	2.6	2.1	2.4	2.2	1.7	2.1	2.3	2.3	2.4	3.1
Eye problems/disorders: None of the above	0.2	0.3	1.5	-1.0	0.1	0.1	-0.1	-1.2	-0.5	0.7	-0.1	-0.2	0.1	0.6	0.2	0.3	-0.1	-0.5	-0.5	-0.2
Mouth/teeth dental problems: Loose teeth	0.5	0.5	3.2	-0.1	-0.1	-0.6	-1.8	-0.3	-1.1	1.1	0.1	-0.3	0.0	-0.4	-0.9	0.0	0.3	-0.8	-1.1	-0.6
Emphysema/chronic bronchitis	1.9	2.2	6.9	0.8	0.7	-2.6	0.2	0.5	0.4	-0.5	-2.1	-1.3	-2.0	-1.8	-1.0	-2.1	-2.1	-0.7	-0.8	-1.8
Medication for pain relief, constipation, heartburn	0.9	1.5	7.6	-2.8	2.6	1.1	0.9	-1.1	0.5	0.4	-0.6	-0.8	-0.5	0.9	-0.3	-0.2	-0.4	-1.9	-1.4	-0.8
Neck or shoulder pain in last month	1.4	1.9	3.6	-1.8	1.2	-0.8	0.2	-0.7	0.2	0.4	-1.8	-1.7	-1.8	-1.9	-1.1	-1.9	-1.6	-1.5	-1.1	-1.8
Medication: Blood pressure	0.7	1.2	6.7	2.2	-1.5	-2.6	0.2	0.4	0.5	-0.4	0.1	0.3	0.1	-1.2	-0.4	0.0	-0.1	1.7	1.1	0.6
Angina (self-reported)	1.6	2.2	5.0	-0.5	1.5	0.5	1.3	1.1	1.5	0.8	-2.1	-1.0	-2.2	-2.0	-0.4	-2.2	-2.1	-0.9	-0.9	-1.6
Migraine (self-reported)	1.7	2.2	4.6	0.9	-2.1	-0.5	-1.7	-0.5	-0.9	-0.6	1.9	1.5	2.0	1.3	1.3	1.6	1.8	1.7	1.6	1.6
Medication: Ibuprofen	0.8	0.9	2.3	0.5	0.0	0.8	0.0	1.2	0.2	-0.8	1.0	1.3	1.2	0.8	1.1	1.3	0.8	1.5	1.3	0.9
Medication: Allopurinol	1.2	1.6	7.3	1.7	-1.3	2.2	-0.9	2.7	-1.2	-2.5	0.2	0.1	0.4	-0.7	-0.0	0.7	0.0	0.9	0.1	0.6
Medication: Omeprazole	0.7	0.8	2.5	-1.6	-1.3	-1.4	0.6	-0.5	0.5	0.2	-1.0	-0.9	-1.1	-0.5	-0.3	-0.7	-1.0	-0.3	0.2	-1.2
Medication: Seretide 50 evohaler	0.5	0.5	3.1	-0.1	0.5	-1.8	0.2	0.2	0.2	-0.6	-0.8	-0.3	-0.9	-1.3	-0.5	-1.0	-0.7	-0.2	-0.5	-0.4
Mean time to correctly identify matches	0.6	1.1	3.1	0.4	0.7	-0.6	0.2	-0.7	0.5	0.4	-1.5	-1.0	-1.7	-0.4	-0.6	-1.6	-1.6	-1.1	-1.2	-1.2
Heart disease (mother)	0.8	0.9	3.2	1.1	1.3	-1.5	-0.1	1.8	0.3	-1.3	-0.9	-0.2	-0.8	-0.7	-0.2	-0.7	-0.9	-0.6	-1.1	-0.9
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.5	0.6	2.1	0.4	-0.2	-0.3	-0.8	1.3	-0.8	-1.4	-0.6	-0.7	-0.3	-1.3	-1.0	0.1	-0.6	0.1	-0.7	-0.4
Whole body fat mass	0.4	1.5	6.6	1.0	-0.3	0.2	-0.8	2.6	-1.8	-2.0	-0.7	-1.3	-0.5	-1.9	-1.7	0.1	-0.8	0.4	-0.7	-0.1
Leg fat mass (right)	0.3	1.2	5.9	0.6	-0.4	0.5	-0.9	2.4	-1.7	-1.6	-0.7	-1.4	-0.5	-1.6	-1.3	0.2	-0.8	0.3	-0.7	-0.1
Arm predicted mass (right)	0.1	0.6	2.8	-0.5	-0.1	1.1	0.2	0.4	-0.5	-0.9	0.9	-0.0	0.8	0.2	0.8	1.2	0.8	0.3	0.2	1.7
Pulse rate, automated reading	0.4	1.3	3.9	-0.7	-0.0	-0.5	-1.3	-1.9	0.4	-0.2	1.2	1.0	1.4	1.8	1.1	2.0	1.4	0.1	0.8	1.2
Alcohol intake frequency.	0.2	0.5	1.8	-0.1	-0.1	1.0	0.1	-1.3	0.2	0.4	-0.6	-1.1	-0.6	0.1	0.6	-0.8	-0.6	-1.1	-0.3	-0.4
Comparative height size at age 10	0.1	0.4	1.2	-1.1	0.3	0.6	-0.9	-0.8	-0.5	0.4	0.5	0.1	0.6	0.7	0.2	1.0	0.6	-0.1	0.1	0.4
Number of full sisters	1.3	1.6	7.1	1.1	-1.2	2.7	-0.9	2.6	-1.2	-0.6	-0.0	-0.3	0.2	-2.0	-1.8	-0.3	-0.1	1.1	0.0	0.3
Suffer from ‘nerves’	0.9	1.4	5.0	-1.0	-1.5	0.3	-0.6	-0.7	-1.2	0.7	-1.2	-2.2	-1.4	-0.7	-1.2	-1.2	-1.4	-1.3	-0.8	-1.1
Overall health rating	1.6	3.3	8.5	-0.4	1.2	-1.7	1.3	0.2	-0.3	0.1	-2.3	-2.3	-2.6	-2.4	-2.9	-2.5	-2.5	-1.0	-1.3	-1.9
Chest pain or discomfort	0.9	1.3	3.1	-0.3	-0.4	-0.9	1.6	0.7	0.3	-1.0	-1.3	-1.6	-1.6	-1.8	-0.9	-1.4	-1.6	0.2	0.4	-0.9
Had major operations	1.4	1.6	10.0	-2.2	1.1	-1.7	1.9	-0.2	3.2	0.8	-0.0	0.2	-0.0	0.1	0.2	-0.5	-0.1	1.2	1.6	-0.1
Age at last live birth	1.2	1.7	3.8	1.7	-0.2	1.0	-0.5	-0.1	-0.4	0.3	1.4	1.8	2.0	1.7	1.1	1.4	1.5	1.6	1.3	1.8
Family relationship satisfaction	1.1	1.3	5.4	1.1	-1.3	-1.1	-0.1	1.0	-1.3	-0.8	1.1	1.0	1.1	-0.8	-0.5	1.0	1.1	2.3	1.1	1.6
Leg pain on walking	0.3	0.4	1.1	-0.7	0.7	1.0	-0.9	-0.3	-0.4	-0.5	0.7	0.1	0.5	0.4	-0.9	0.6	0.8	-0.1	0.2	0.5
Qualifications: NVQ or HND or HNC or equivalent	1.0	1.2	5.4	1.7	-2.1	0.1	-0.5	1.5	-0.2	-2.3	0.5	0.6	0.7	-0.6	-0.4	1.1	0.3	1.5	0.9	0.1
Commuting to job workplace: Car/motor vehicle	0.3	0.3	2.4	0.8	0.2	0.1	-0.5	1.5	0.1	0.2	-0.1	0.7	0.2	-0.6	-0.2	-0.1	0.0	0.8	0.3	0.3
Illness, injury, bereavement, stress in last 2 years	0.5	0.6	2.5	-1.6	-0.4	1.0	-0.4	-0.8	0.3	1.5	0.1	0.1	-0.2	1.3	-0.6	-0.1	0.2	-0.9	-0.0	-0.5
Medication: Aspirin	0.4	0.5	1.9	1.4	-0.4	-0.7	0.3	0.4	0.8	1.1	-0.3	-0.1	-0.4	-1.0	0.3	-1.0	-0.3	0.7	0.8	0.2
Supplements: Vitamin C	0.9	1.0	3.1	-1.5	1.2	-0.4	0.5	-1.6	1.1	-0.5	0.8	0.8	0.6	1.8	1.5	0.8	1.0	-0.8	0.2	0.2
Knee pain experienced in last month	0.5	0.7	3.3	-0.6	1.8	0.6	-0.1	0.7	-0.2	-1.5	-0.8	-1.1	-0.6	-0.5	-0.2	-0.4	-0.8	-0.8	-1.0	-0.7
Hypertension (Self-reported)	3.3	9.3	27.7	3.0	-2.2	-0.7	0.4	2.6	2.6	-2.7	3.2	3.2	3.2	0.6	2.4	2.9	2.8	5.3	4.8	4.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.2	1.5	4.5	-1.7	0.0	-0.5	-0.5	0.1	-0.8	-0.8	-1.6	-2.1	-1.5	-1.3	-0.1	-1.4	-1.6	-1.1	-1.1	-1.5
Illnesses of father: Heart disease	1.1	1.5	8.6	-2.9	-0.6	0.0	0.6	-0.3	2.4	-0.9	0.9	0.8	0.7	1.5	1.4	1.1	0.9	0.2	1.2	0.5
Illnesses of siblings: Diabetes	0.3	0.4	1.6	-1.0	-0.5	-0.2	0.6	0.0	0.4	-0.2	0.5	0.4	0.5	0.4	1.3	1.0	0.5	0.4	1.0	-0.0
Smoking status: Previous	0.4	0.6	1.3	0.6	0.7	-0.9	0.2	0.7	0.4	-0.8	-0.8	-0.6	-1.0	-0.9	-0.5	-1.2	-0.9	-0.5	-1.0	-0.5
Forced expiratory volume in 1-second (FEV1), predicted	0.4	0.7	1.9	-0.8	-0.8	1.4	-0.1	-1.2	0.7	-0.2	0.9	0.2	0.8	1.1	1.2	1.1	0.9	-0.3	0.6	0.8
Whole body fat-free mass	0.1	0.5	1.8	-0.3	-0.4	0.9	-0.0	0.4	-0.5	-1.3	0.8	-0.1	0.7	0.1	0.6	1.1	0.7	0.3	0.3	1.4
Leg fat-free mass (right)	0.1	0.4	2.1	-0.6	-0.3	1.0	-0.3	0.5	-0.9	-1.4	0.1	-0.8	0.1	-0.5	-0.1	0.5	0.1	-0.5	-0.5	0.5
Arm fat percentage (left)	0.5	1.9	5.7	1.1	-0.6	0.3	-1.8	2.4	-2.3	-1.6	-0.7	-1.4	-0.6	-2.1	-2.0	-0.2	-0.8	0.1	-1.0	-0.4
Average weekly red wine intake	2.6	3.8	8.5	0.2	-1.3	1.1	-0.5	0.3	0.3	-0.3	2.9	2.8	2.6	1.8	0.9	2.9	2.7	2.5	2.5	2.4
Handedness (chirality/laterality): Left-handed	0.9	1.1	2.7	1.7	1.5	1.3	-0.3	1.1	0.3	0.6	0.9	1.0	1.1	1.0	1.6	0.8	0.9	0.4	-0.2	1.3
Mood swings	0.8	1.5	3.9	-0.4	-1.5	-0.1	-1.1	1.4	-1.8	0.9	-1.4	-1.6	-1.1	-2.0	-1.0	-1.3	-1.3	-0.0	-0.5	-1.0
Loneliness, isolation	4.1	5.6	14.1	-0.1	-0.5	-0.2	0.6	0.9	-1.8	0.5	-3.3	-3.3	-3.1	-3.8	-2.2	-3.0	-3.2	-2.2	-2.6	-3.2
Long-standing illness, disability or infirmity	0.5	0.8	3.2	0.8	0.9	-1.7	0.4	1.0	0.3	-0.0	-0.8	-0.6	-0.6	-1.8	-0.7	-1.1	-0.8	0.7	-0.0	-0.2
Ever had bowel cancer screening	1.4	1.6	4.0	-0.2	0.7	-0.6	1.2	0.9	0.3	-0.5	-1.8	-1.2	-2.0	-1.4	-1.5	-1.8	-1.8	-1.0	-0.8	-1.5
Diabetes diagnosed by doctor	1.1	1.7	4.1	0.0	0.5	-0.1	0.7	0.3	0.1	-0.7	-1.8	-1.9	-2.0	-1.5	-1.2	-1.8	-1.9	-1.5	-1.2	-1.6
Ever had stillbirth, spontaneous miscarriage or termination	0.4	0.5	1.4	0.3	-0.8	1.2	0.0	0.8	-1.0	-0.1	-0.8	-0.9	-0.6	-1.0	-0.5	-0.5	-0.8	-0.0	-0.3	-0.5
Friendships satisfaction	0.8	1.0	3.3	1.7	-1.0	0.4	1.8	0.6	-0.5	-0.9	-1.1	-0.6	-1.1	-1.6	-0.2	-1.2	-1.2	0.1	0.0	-0.6
Qualifications: nursing, teaching	2.0	3.1	11.2	0.2	-2.1	0.9	-0.4	1.4	1.6	-3.3	2.0	1.7	1.8	1.2	1.5	1.9	1.9	2.0	2.2	1.5
Commuting to job workplace: Walk	0.3	0.3	3.6	0.0	0.1	1.9	0.9	-0.2	0.1	0.1	0.0	-0.1	-0.0	0.0	-0.2	-0.4	-0.0	0.3	0.4	0.3
Eye problems/disorders: Cataract	0.2	0.2	0.4	0.6	-0.0	0.2	-0.1	0.6	0.4	-0.0	-0.4	-0.3	-0.6	-0.4	-0.7	-0.6	-0.2	-0.5	-0.3	-0.6
Mouth/teeth dental problems: Mouth ulcers	1.1	1.7	11.2	1.6	1.1	-0.3	0.3	3.4	1.0	-1.1	0.3	1.3	0.9	-0.8	-0.6	0.0	0.3	2.4	1.6	0.6
Medication for cholesterol	1.7	2.5	5.4	0.4	1.2	0.4	-0.4	-0.3	-2.2	1.1	-2.2	-1.6	-1.7	-1.0	-2.0	-2.0	-2.0	-1.8	-2.3	-1.7
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.5	0.6	2.4	0.9	-1.4	0.3	-0.6	1.6	-1.1	-0.4	0.0	0.6	-0.1	-1.5	0.2	-0.3	-0.0	0.3	-0.5	-0.2
Back pain experienced in last month	1.1	1.5	4.4	-1.1	1.1	-1.0	-0.0	0.7	0.8	0.1	-1.9	-1.4	-2.1	-1.2	0.2	-1.6	-2.1	-0.8	-0.7	-1.4
Mineral and other dietary supplements	0.9	1.3	2.9	-0.3	-1.5	-1.2	-0.2	-0.2	-1.7	0.4	-1.2	-1.7	-1.1	-1.4	-1.2	-0.8	-1.3	-0.6	-1.2	-1.4
Breast cancer (self-reported)	0.3	0.3	2.1	0.5	-0.2	0.4	-0.5	0.9	0.1	-1.4	0.2	0.5	0.6	0.1	0.0	0.9	0.3	0.6	0.3	-0.1
Asthma (self-reported)	0.2	0.4	1.6	-0.4	-0.3	0.5	1.1	0.2	1.3	-0.3	-0.7	-0.5	-0.9	-0.3	-0.2	-0.9	-0.7	-0.4	0.1	-0.3
Osteoporosis (self-reported)	0.7	0.8	3.5	1.9	-1.1	0.8	-0.3	0.9	1.1	-0.6	0.5	0.7	0.4	0.2	-1.3	0.4	0.3	1.3	1.1	0.5
Osteoarthritis (self-reported)	1.6	2.0	8.0	-2.8	2.8	0.8	1.0	-1.2	2.8	1.1	-0.4	-0.6	-0.8	1.5	0.6	-0.6	-0.6	-1.3	0.1	-0.7
Medication: Aspirin	0.3	0.4	1.7	1.3	0.1	-0.2	0.3	0.7	0.8	0.8	-0.4	-0.1	-0.4	-1.0	0.5	-1.0	-0.4	0.5	0.5	-0.1
Medication: Gliclazide	0.8	0.9	2.0	0.6	1.2	0.3	0.2	0.9	-0.2	-0.7	-1.3	-1.3	-1.4	-1.0	-0.5	-1.4	-1.4	-0.6	-1.0	-0.5
Illnesses of father: None of the above (group 1)	1.2	1.5	3.6	-0.3	1.8	-1.3	0.3	-1.0	-1.5	1.4	-1.3	-1.0	-1.0	-0.3	-1.0	-1.2	-1.2	-1.6	-1.9	-1.1
Smoking status: Current	0.5	0.8	2.6	-1.5	1.6	-0.3	0.5	0.5	0.9	-0.5	0.9	0.3	1.1	0.3	0.6	1.3	0.8	1.3	0.8	0.7
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.6	1.3	3.2	1.1	-1.8	-0.8	-0.6	0.9	-1.1	-1.3	-1.3	-0.9	-1.0	-1.6	-0.3	-1.3	-1.1	-0.6	-1.0	-1.7
Whole body water mass	0.1	0.5	1.8	-0.3	-0.4	0.7	-0.1	0.4	-0.5	-1.3	0.8	-0.1	0.7	0.1	0.6	1.1	0.7	0.3	0.3	1.3
Leg predicted mass (right)	0.1	0.4	2.2	-0.6	-0.3	1.0	-0.3	0.5	-0.9	-1.5	0.1	-0.7	0.1	-0.5	-0.1	0.6	0.1	-0.5	-0.5	0.5
Arm fat mass (left)	0.3	1.1	3.4	0.6	-0.4	0.3	-1.3	1.8	-1.8	-1.5	-0.5	-1.2	-0.4	-1.6	-1.5	0.1	-0.5	0.1	-0.7	-0.0
Number of self-reported non-cancer illnesses	0.7	1.1	6.7	1.3	-0.1	-0.5	1.0	2.6	0.6	-1.9	0.0	0.3	-0.2	-1.4	0.5	-0.4	-0.2	1.5	0.9	0.7
Average weekly champagne plus white wine intake	1.2	1.6	4.8	0.1	-2.2	2.0	-1.4	0.2	-0.6	-1.1	1.4	0.9	1.6	1.0	0.6	1.8	1.4	1.1	1.1	0.9
Miserableness	0.5	0.8	6.2	0.1	-2.5	-0.3	-1.0	0.8	-1.2	-0.6	-0.4	-1.0	-0.3	-1.0	-0.5	-0.5	-0.6	0.9	0.8	-0.1
Guilty feelings	3.8	5.8	14.2	1.8	-0.8	1.0	0.5	3.0	-1.9	-0.4	-3.0	-3.4	-3.0	-3.8	-2.4	-3.2	-3.5	-0.5	-1.5	-2.4
Wears glasses or contact lenses	0.4	0.4	2.3	-0.4	0.5	-0.6	-0.2	-0.8	1.3	-0.9	0.1	0.3	0.1	1.5	0.7	0.5	0.1	-0.5	0.1	-0.4
Ever taken oral contraceptive pill	0.7	0.8	3.3	0.7	-0.5	-1.8	-1.0	1.2	-1.1	-0.7	-0.5	-0.7	-0.4	-0.7	-1.6	0.1	-0.7	0.6	-0.0	-0.6
Hearing aid user	0.8	0.9	2.9	0.3	0.4	-0.7	-0.6	0.3	1.7	-0.1	1.0	1.0	1.1	0.9	1.4	0.9	0.9	1.2	1.1	1.0
Mother’s age at death	0.3	0.3	2.1	0.3	0.5	-1.4	0.0	-0.5	-0.1	-0.6	0.5	1.1	0.5	0.1	0.3	0.2	0.5	0.7	0.5	0.1
Financial situation satisfaction	0.9	1.1	4.4	2.1	-1.8	-0.1	-0.6	1.8	-1.1	-1.6	-0.3	-0.5	0.0	-1.1	-0.8	0.0	-0.5	1.2	0.5	0.8
Tinnitus: Yes, now most or all of the time	0.3	0.4	1.7	0.0	-0.1	1.2	-0.8	0.6	-1.3	-0.7	-0.2	-0.5	0.1	-0.4	0.3	0.1	-0.1	-0.0	-0.8	0.3
Commuting to job workplace: Public transport	0.8	1.0	2.6	-0.5	1.2	1.0	0.5	-0.6	0.5	1.0	1.3	1.1	1.3	1.6	0.9	1.2	1.2	0.4	0.5	1.1
Eye problems/disorders: Glaucoma	0.7	0.8	2.7	1.2	0.2	0.6	-0.8	1.6	-0.7	-1.3	0.8	0.1	0.7	-0.8	-0.1	0.3	0.6	1.3	0.6	1.3
Medication: Blood pressure	1.5	2.8	5.9	0.2	-1.5	-0.7	0.8	0.6	1.8	-0.8	2.2	2.1	1.9	1.2	1.7	1.6	2.2	2.1	2.4	2.2
Pain type(s) experienced in last month: Hip pain	0.7	0.9	4.1	0.6	0.7	2.0	-0.4	0.8	-0.3	-1.0	-0.8	-0.9	-0.8	-1.6	-0.9	-0.9	-0.9	0.0	-0.1	-1.0
Supplements: Fish oil (including cod liver oil)	0.3	0.4	1.9	1.3	-0.0	1.1	0.1	1.0	0.5	-1.4	0.2	0.8	0.3	0.2	0.4	0.1	0.2	0.3	0.1	0.4
High cholesterol (Self-reported)	1.1	1.9	6.6	1.3	0.1	-0.5	-0.2	2.4	0.2	-2.6	1.2	1.4	1.2	-0.1	0.8	1.4	1.1	2.2	1.0	1.6
Medication: Bendroflumethiazide	1.7	2.6	4.9	0.8	-2.2	-1.6	-0.8	-0.5	0.9	0.3	2.1	1.9	1.9	0.6	1.5	1.7	2.2	1.9	2.1	2.0
Medication: Paracetamol	0.6	1.0	4.2	2.1	-0.7	0.0	-0.4	1.6	-0.6	-1.4	0.4	1.2	0.7	-0.6	0.9	0.9	0.5	1.2	0.7	0.7
Medication: Lisinopril	1.2	1.5	4.1	0.5	1.2	-1.6	1.9	-0.1	2.0	1.2	1.1	1.6	0.6	0.4	0.8	0.5	0.8	1.6	1.6	1.4
Medication: Atorvastatin	0.6	0.8	4.0	-0.8	0.1	1.7	-1.3	1.6	-0.5	-2.0	0.3	-0.1	0.4	-0.1	0.6	0.3	0.4	0.4	0.2	0.2
Illnesses of father: High blood pressure	2.9	3.5	14.4	2.0	-1.7	2.3	-0.5	3.8	0.7	-3.0	1.4	1.2	1.5	-0.5	0.1	1.2	1.1	3.0	1.7	1.7
Alcohol drinker status: Never	0.5	0.5	2.7	0.0	0.3	0.1	-0.1	-1.6	0.1	1.4	-0.5	-0.5	-0.6	0.4	1.3	-0.8	-0.6	-0.6	-0.1	0.3
Ever smoked	0.3	0.5	1.7	0.2	1.3	-0.8	0.5	1.0	0.8	-1.1	0.4	0.3	0.3	-0.3	-0.4	0.2	0.3	0.9	0.1	0.8
Basal metabolic rate	0.1	0.4	2.1	-0.1	-0.5	0.7	-0.2	0.7	-0.8	-1.4	0.6	-0.4	0.5	-0.2	0.3	1.0	0.5	0.3	0.1	1.1
Leg fat percentage (left)	0.3	1.2	6.9	0.8	-0.1	0.2	-0.9	2.6	-1.5	-1.5	-0.6	-1.1	-0.4	-1.4	-1.4	0.1	-0.8	0.5	-0.8	-0.3
Arm fat-free mass (left)	0.1	0.5	2.2	-0.4	-0.0	0.4	0.3	0.6	-0.2	-1.5	0.8	-0.0	0.8	0.2	0.6	1.2	0.7	0.4	0.2	1.4
Number of operations (self-reported)	0.9	1.3	7.9	-1.0	1.8	0.5	1.2	0.1	2.8	0.7	0.6	1.1	0.5	0.3	1.1	0.1	0.7	1.2	1.4	0.5
Average weekly beer plus cider intake	1.5	2.2	4.5	-1.3	2.1	-0.7	0.4	1.0	-0.2	-0.3	-2.0	-2.1	-1.9	-1.8	-0.3	-1.8	-2.1	-1.0	-1.3	-2.0
Irritability	1.2	2.0	5.1	-0.8	0.1	1.2	-0.6	-0.2	-0.6	1.5	-2.1	-2.3	-2.0	-1.6	-0.3	-2.3	-2.1	-0.9	-0.5	-1.3
Risk taking	1.3	1.9	4.9	1.7	-0.8	-0.2	-1.1	2.2	-2.0	-1.0	-1.1	-1.8	-1.1	-2.2	-1.3	-0.8	-1.4	0.2	-1.6	-0.4
Ever had prostate specific antigen (PSA) test	2.0	2.3	9.8	1.8	0.3	-0.4	0.9	2.6	1.3	-1.4	0.9	1.8	0.9	-0.7	0.1	0.8	0.8	3.1	2.5	1.0
Fractured/broken bones in last 5 years	0.9	1.1	3.9	1.1	-0.8	1.0	-1.6	2.0	-1.3	-1.4	0.7	0.3	0.8	-0.4	-0.5	0.9	0.6	1.5	-0.0	0.9
Age started oral contraceptive pill	0.7	0.9	3.2	0.2	0.6	-0.0	1.2	-1.4	0.8	1.8	0.8	1.4	0.6	1.5	0.8	0.6	0.9	-0.4	0.7	0.4
Diastolic blood pressure, automated reading	7.4	23.1	47.7	2.2	-1.7	-1.1	-2.0	1.4	2.3	-1.6	6.5	6.2	6.5	4.5	4.3	6.9	6.1	6.2	6.2	6.7
Ever depressed for a whole week	0.8	1.0	5.7	0.8	-0.2	-0.7	-0.3	2.4	0.0	-2.0	-0.9	-0.8	-0.7	-1.2	0.1	-0.5	-1.2	0.5	-0.2	-0.3
Unable to work because of sickness or disability	1.7	2.2	7.2	0.1	0.6	0.1	-0.9	1.6	-1.6	-0.7	-1.6	-1.9	-1.6	-2.7	-2.0	-1.6	-1.7	-0.4	-1.6	-1.5
Commuting to job workplace: Cycle	0.6	0.7	1.9	-0.1	0.6	0.3	0.8	-0.8	-0.1	0.0	-1.2	-0.9	-1.2	-0.7	-1.0	-1.4	-1.3	-0.7	-1.1	-0.6
Myopia	0.7	1.0	3.1	-0.9	1.2	1.4	0.2	-0.2	1.0	1.3	0.8	1.0	0.8	1.8	1.2	0.8	0.8	0.4	0.7	0.6
Vascular/heart problems diagnosed by doctor	2.8	7.6	21.2	-2.8	2.4	-0.4	-0.2	-2.9	-2.4	3.0	-2.8	-2.7	-2.7	-0.4	-2.2	-2.4	-2.5	-4.6	-4.2	-3.8
Cholesterol lowering medication	0.6	0.8	3.6	-0.4	0.9	0.6	0.3	1.2	1.9	-1.1	0.9	0.8	0.6	0.5	0.9	0.8	0.9	0.8	1.0	0.8
Medication: Omeprazole (e.g. Zanprol)	0.6	0.7	2.1	-0.9	-1.4	-0.6	1.0	0.1	0.6	-0.5	-1.0	-1.0	-1.3	-0.6	-0.4	-0.8	-1.2	-0.2	0.3	-1.1
Pain experienced in last month	0.7	1.1	3.7	0.3	0.9	-0.4	-0.2	-0.2	0.2	1.0	1.3	1.9	1.3	1.2	0.9	1.4	1.5	0.8	0.6	1.3
Supplements: Calcium	0.5	0.6	3.4	-0.4	1.6	-0.1	-0.6	-1.1	1.9	-0.0	-0.0	0.4	-0.1	0.9	-1.0	-0.1	0.0	-0.6	0.2	-0.5
Basal cell carcinoma (self-reported)	0.6	0.8	3.1	0.4	0.9	0.3	1.8	0.5	0.3	-0.8	-0.8	-0.7	-0.9	-1.7	-0.8	-1.1	-0.9	0.2	-0.0	-0.4
Heart attack/myocardial infarction (self-reported)	0.9	1.2	7.0	-2.6	0.7	1.0	0.9	-1.3	2.2	0.9	-0.2	-0.3	-0.6	1.4	0.6	-0.5	-0.2	-0.8	0.4	-0.6
Deep venous thrombosis (DVT) (self-reported)	0.9	1.1	3.0	1.6	1.5	0.1	1.3	1.4	0.7	1.2	0.4	1.2	0.4	0.0	0.6	0.4	0.2	1.7	1.2	1.6
Heart disease (siblings)	0.8	1.0	3.7	-0.7	-0.2	0.1	0.5	-0.5	-0.3	-1.0	-1.3	-1.3	-1.1	-0.4	-0.4	-0.7	-1.1	-1.9	-1.3	-1.5
Alcohol drinker status: Previous	0.5	0.5	1.8	-0.3	-0.7	0.3	0.3	0.3	-0.7	-1.4	1.0	0.9	1.2	0.1	-0.4	1.0	1.1	0.7	0.3	0.2
Pack years of smoking	0.8	1.1	2.5	-1.4	0.0	0.3	0.2	-0.1	-0.2	1.0	-1.4	-1.4	-1.6	-1.3	-0.8	-1.5	-1.3	-1.0	-0.5	-1.5
Impedance of whole body	0.0	0.2	0.9	0.9	-0.2	-0.5	0.6	0.3	0.5	0.1	0.0	0.6	0.1	-0.2	-0.3	-0.3	-0.0	0.7	0.7	-0.4
Leg fat mass (left)	0.3	1.3	5.5	0.5	-0.2	0.2	-0.7	2.3	-1.6	-1.6	-0.8	-1.4	-0.6	-1.6	-1.5	0.0	-0.9	0.2	-0.9	-0.2
Arm predicted mass (left)	0.1	0.6	2.6	-0.6	-0.1	0.4	0.0	0.3	-0.3	-1.2	1.0	0.1	0.9	0.6	0.7	1.4	0.9	0.5	0.3	1.6