[Hub]/) : Traits : Respiratory disease : ← →

chr6:134,905,567-136,516,257

Best TWAS P=8.1e-10 · Best GWAS P=4.09e-08 conditioned to 0.651

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Artery Aorta	AHI1	0.28	0.01	enet	27	0.08	3.2e-05	3.4	-5.7	1.2e-08	-0.74	0.04	0.91	FALSE
2	GTEx	Artery Tibial	AHI1	0.11	0.03	enet	16	0.09	1.8e-07	4.0	-5.3	1.1e-07	-0.71	0.04	0.96	FALSE
3	GTEx	Brain Caudate basal ganglia	AHI1	0.25	0.06	enet	24	0.15	5.4e-05	2.7	-5.2	1.9e-07	-0.67	0.04	0.74	FALSE
4	GTEx	Brain Cortex	RP3-388E23.2	0.28	0.16	enet	13	0.19	5.8e-06	3.4	-5.4	5.8e-08	-0.72	0.10	0.80	FALSE
5	GTEx	Brain Frontal Cortex BA9	AHI1	0.19	0.00	enet	14	0.05	1.5e-02	2.3	-6.1	8.1e-10	-0.52	0.05	0.30	TRUE
6	GTEx	Breast Mammary Tissue	AHI1	0.34	0.29	lasso	4	0.35	1.1e-18	3.4	-5.2	2.5e-07	-0.66	0.92	0.02	FALSE
7	GTEx	Cells EBV-transformed lymphocytes	AHI1	0.38	0.24	enet	19	0.23	5.4e-08	5.2	-5.9	3.7e-09	-0.64	0.01	0.99	TRUE
8	GTEx	Cells EBV-transformed lymphocytes	RP3-388E23.2	0.26	0.05	lasso	6	0.02	7.1e-02	5.4	-5.3	1.0e-07	-0.66	0.01	0.94	FALSE
9	GTEx	Cells Transformed fibroblasts	AHI1	0.44	0.21	enet	22	0.32	4.4e-24	4.8	-5.5	3.5e-08	-0.69	0.08	0.92	FALSE
10	GTEx	Esophagus Mucosa	AHI1	0.30	0.24	lasso	8	0.32	4.6e-22	5.4	-5.7	9.8e-09	-0.69	0.01	0.99	FALSE
11	GTEx	Skin Not Sun Exposed Suprapubic	AHI1	0.41	0.31	lasso	7	0.40	9.1e-24	5.5	-5.8	8.0e-09	-0.72	0.00	0.99	FALSE
12	GTEx	Skin Not Sun Exposed Suprapubic	RP3-388E23.2	0.14	0.03	enet	17	0.12	3.7e-07	5.1	-5.7	1.5e-08	-0.76	0.02	0.95	FALSE
13	GTEx	Skin Sun Exposed Lower leg	AHI1	0.33	0.22	enet	14	0.34	1.0e-28	3.4	-5.6	2.2e-08	-0.71	0.35	0.62	FALSE
14	GTEx	Spleen	AHI1	0.31	0.21	lasso	3	0.38	8.6e-11	5.1	-5.8	5.5e-09	-0.78	0.01	0.96	FALSE
15	GTEx	Testis	AHI1	0.37	0.32	enet	25	0.37	3.5e-17	5.4	-5.9	2.8e-09	-0.71	0.01	0.99	FALSE
16	GTEx	Testis	RP3-388E23.2	0.23	0.19	lasso	3	0.24	5.7e-11	3.4	-5.2	2.5e-07	-0.64	0.14	0.84	FALSE
17	METSIM	Adipose	AHI1	0.25	0.22	lasso	7	0.28	1.1e-42	5.2	-5.7	1.1e-08	-0.68	0.01	0.99	FALSE
18	NTR	Blood	AHI1	0.11	0.14	lasso	6	0.15	3.2e-47	5.4	-5.2	2.0e-07	-0.57	0.01	0.99	FALSE
19	YFS	Blood	AHI1	0.24	0.30	bslmm	414	0.33	1.4e-110	5.5	-5.6	2.4e-08	-0.68	0.01	0.99	FALSE
20	The Cancer Genome Atlas	Breast Invasive Carcinoma	AHI1	0.06	0.02	lasso	7	0.02	1.3e-04	5.4	-5.7	1.4e-08	-0.78	0.01	0.99	FALSE
21	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	AHI1	0.18	0.19	lasso	4	0.18	6.4e-20	5.5	-5.5	4.3e-08	-0.64	0.00	0.99	FALSE
22	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	AHI1	0.05	0.00	blup	73	0.02	7.1e-04	3.4	-5.3	1.4e-07	-0.67	0.01	0.44	FALSE
23	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	AHI1	0.13	0.16	lasso	3	0.16	1.2e-17	5.4	-5.6	2.1e-08	-0.68	0.00	1.00	FALSE
24	The Cancer Genome Atlas	Ovarian Serous Cystadenocarcinoma	AHI1	0.05	0.05	lasso	1	0.04	1.5e-03	5.2	-5.2	1.6e-07	-0.61	0.01	0.92	FALSE
25	The Cancer Genome Atlas	Testicular Germ Cell Tumors	AHI1	0.36	0.30	lasso	3	0.29	1.0e-10	5.2	-5.7	1.3e-08	-0.72	0.01	0.99	FALSE