[Hub]/) : Traits : Respiratory disease :

chr6:134,905,567-136,516,257

Best TWAS P=8.1e-10 · Best GWAS P=4.09e-08 conditioned to 0.651

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Aorta AHI1 0.28 0.01 enet 27 0.08 3.2e-05 3.4 -5.7 1.2e-08 -0.74 0.04 0.91 FALSE
2 GTEx Artery Tibial AHI1 0.11 0.03 enet 16 0.09 1.8e-07 4.0 -5.3 1.1e-07 -0.71 0.04 0.96 FALSE
3 GTEx Brain Caudate basal ganglia AHI1 0.25 0.06 enet 24 0.15 5.4e-05 2.7 -5.2 1.9e-07 -0.67 0.04 0.74 FALSE
4 GTEx Brain Cortex RP3-388E23.2 0.28 0.16 enet 13 0.19 5.8e-06 3.4 -5.4 5.8e-08 -0.72 0.10 0.80 FALSE
5 GTEx Brain Frontal Cortex BA9 AHI1 0.19 0.00 enet 14 0.05 1.5e-02 2.3 -6.1 8.1e-10 -0.52 0.05 0.30 TRUE
6 GTEx Breast Mammary Tissue AHI1 0.34 0.29 lasso 4 0.35 1.1e-18 3.4 -5.2 2.5e-07 -0.66 0.92 0.02 FALSE
7 GTEx Cells EBV-transformed lymphocytes AHI1 0.38 0.24 enet 19 0.23 5.4e-08 5.2 -5.9 3.7e-09 -0.64 0.01 0.99 TRUE
8 GTEx Cells EBV-transformed lymphocytes RP3-388E23.2 0.26 0.05 lasso 6 0.02 7.1e-02 5.4 -5.3 1.0e-07 -0.66 0.01 0.94 FALSE
9 GTEx Cells Transformed fibroblasts AHI1 0.44 0.21 enet 22 0.32 4.4e-24 4.8 -5.5 3.5e-08 -0.69 0.08 0.92 FALSE
10 GTEx Esophagus Mucosa AHI1 0.30 0.24 lasso 8 0.32 4.6e-22 5.4 -5.7 9.8e-09 -0.69 0.01 0.99 FALSE
11 GTEx Skin Not Sun Exposed Suprapubic AHI1 0.41 0.31 lasso 7 0.40 9.1e-24 5.5 -5.8 8.0e-09 -0.72 0.00 0.99 FALSE
12 GTEx Skin Not Sun Exposed Suprapubic RP3-388E23.2 0.14 0.03 enet 17 0.12 3.7e-07 5.1 -5.7 1.5e-08 -0.76 0.02 0.95 FALSE
13 GTEx Skin Sun Exposed Lower leg AHI1 0.33 0.22 enet 14 0.34 1.0e-28 3.4 -5.6 2.2e-08 -0.71 0.35 0.62 FALSE
14 GTEx Spleen AHI1 0.31 0.21 lasso 3 0.38 8.6e-11 5.1 -5.8 5.5e-09 -0.78 0.01 0.96 FALSE
15 GTEx Testis AHI1 0.37 0.32 enet 25 0.37 3.5e-17 5.4 -5.9 2.8e-09 -0.71 0.01 0.99 FALSE
16 GTEx Testis RP3-388E23.2 0.23 0.19 lasso 3 0.24 5.7e-11 3.4 -5.2 2.5e-07 -0.64 0.14 0.84 FALSE
17 METSIM Adipose AHI1 0.25 0.22 lasso 7 0.28 1.1e-42 5.2 -5.7 1.1e-08 -0.68 0.01 0.99 FALSE
18 NTR Blood AHI1 0.11 0.14 lasso 6 0.15 3.2e-47 5.4 -5.2 2.0e-07 -0.57 0.01 0.99 FALSE
19 YFS Blood AHI1 0.24 0.30 bslmm 414 0.33 1.4e-110 5.5 -5.6 2.4e-08 -0.68 0.01 0.99 FALSE
20 The Cancer Genome Atlas Breast Invasive Carcinoma AHI1 0.06 0.02 lasso 7 0.02 1.3e-04 5.4 -5.7 1.4e-08 -0.78 0.01 0.99 FALSE
21 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma AHI1 0.18 0.19 lasso 4 0.18 6.4e-20 5.5 -5.5 4.3e-08 -0.64 0.00 0.99 FALSE
22 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma AHI1 0.05 0.00 blup 73 0.02 7.1e-04 3.4 -5.3 1.4e-07 -0.67 0.01 0.44 FALSE
23 The Cancer Genome Atlas Lung Squamous Cell Carcinoma AHI1 0.13 0.16 lasso 3 0.16 1.2e-17 5.4 -5.6 2.1e-08 -0.68 0.00 1.00 FALSE
24 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma AHI1 0.05 0.05 lasso 1 0.04 1.5e-03 5.2 -5.2 1.6e-07 -0.61 0.01 0.92 FALSE
25 The Cancer Genome Atlas Testicular Germ Cell Tumors AHI1 0.36 0.30 lasso 3 0.29 1.0e-10 5.2 -5.7 1.3e-08 -0.72 0.01 0.99 FALSE